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Application filed by Pomorski Uniwersytet Medyczny W Szczecinie, Cezary Cybulski, Jan LubińskifiledCriticalPomorski Uniwersytet Medyczny W Szczecinie
Priority to PL410186ApriorityCriticalpatent/PL236572B1/en
Publication of PL410186A1publicationCriticalpatent/PL410186A1/en
Publication of PL236572B1publicationCriticalpatent/PL236572B1/en
Measuring Or Testing Involving Enzymes Or Micro-Organisms
(AREA)
Abstract
Wynalazek ujawnia sposoby i produkty znajdujące zastosowanie w diagnozowaniu genetycznej predyspozycji do chorób u ludzi i polega na ocenie czy w materiale biologicznym badanej osoby występuje specyficzna zmiana konstytucyjna w genie PALB2. Wynalazek dotyczy nowej metody diagnostycznej wykrywającej wysoką genetyczną predyspozycję do inwazyjnego raka piersi o złym rokowaniu. Sposób i zestaw diagnostyczny dotyczy opracowania nowego markera złego rokowania dla raka piersi.The invention discloses methods and products used in the diagnosis of genetic predisposition to human diseases and consists in assessing whether a specific constitutional change in the PALB2 gene occurs in the biological material of the examined person. The invention relates to a new diagnostic method detecting a high genetic predisposition to invasive breast cancer with poor prognosis. The method and diagnostic kit concerns the development of a new marker of poor prognosis for breast cancer.
PL410186A2014-11-202014-11-20Method, application and a set for detecting high risk breast cancer with bad prognosis
PL236572B1
(en)
method for identifying an individual with a disease or dysfunction, method for predicting the responsiveness of an individual with a disease or dysfunction, method for determining the likelihood that an individual with a disease or dysfunction will exhibit benefit from treatment, method for selecting a therapy, Uses of a pd-11 Axis Binding Antagonist, Assay to Identify an Individual with a Disease, Diagnostic Kit, Method to Evaluate a Treatment Response, and Method to Monitor the Response of a Treated Individual