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PL406987A1 - Profile of blood protein markers as the test for detecting lung cancer - Google Patents

Profile of blood protein markers as the test for detecting lung cancer

Info

Publication number
PL406987A1
PL406987A1 PL406987A PL40698714A PL406987A1 PL 406987 A1 PL406987 A1 PL 406987A1 PL 406987 A PL406987 A PL 406987A PL 40698714 A PL40698714 A PL 40698714A PL 406987 A1 PL406987 A1 PL 406987A1
Authority
PL
Poland
Prior art keywords
lung cancer
drg
protein markers
test
profile
Prior art date
Application number
PL406987A
Other languages
Polish (pl)
Other versions
PL230661B1 (en
Inventor
Rafał Dziadziuszko
Witold Rzyman
Ewa Szutowicz-Zielińska
Jacek Jassem
Joanna Polańska
Piotr Widłak
Original Assignee
Gdański Uniwersytet Medyczny
Centrum Onkologii - Instytut Im. Marii Skłodowskiej-Curie, Oddział W Gliwicach
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gdański Uniwersytet Medyczny, Centrum Onkologii - Instytut Im. Marii Skłodowskiej-Curie, Oddział W Gliwicach filed Critical Gdański Uniwersytet Medyczny
Priority to PL406987A priority Critical patent/PL230661B1/en
Priority to PCT/PL2015/000009 priority patent/WO2015115922A1/en
Publication of PL406987A1 publication Critical patent/PL406987A1/en
Publication of PL230661B1 publication Critical patent/PL230661B1/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Przedmiotem wynalazku jest metoda predykcyjna do przewidywania i/lub wykluczenia obecności raka płuca polegająca na pomiarze stężenia markerów białkowych w surowicy krwi tj. DRG-cyfra21-1, IBL-hCRP, DRG-NSE, NT-CEA, NT-CA125, USCN-SCCA1, h_tPA, S-100, NT-CA19-9. Ponadto wynalazek obejmuje zestaw testowy do wykrywania raka płuca metodą ELISA, który zawiera wartość referencyjną podaną jako wartość górnego poziomu wartości referencyjnych dla danego markera białkowego w populacji osób zdrowych, do którego odnoszone jest jego stężenie w surowicy osoby badanej pozwalając na oznaczanie następujących markerów białkowych: DRG-cyfra21-1, IBL-hCRP, DRG-NSE, NT-CEA, NT-CA125, USCN-SCCA1, h_tPA, S-100, NT-CA19-9.The subject of the invention is a predictive method for predicting and / or ruling out the presence of lung cancer consisting in measuring the concentration of protein markers in blood serum, i.e. DRG-Cyfr21-1, IBL-hCRP, DRG-NSE, NT-CEA, NT-CA125, USCN-SCCA1 , h_tPA, S-100, NT-CA19-9. In addition, the invention includes a test kit for detecting lung cancer by ELISA, which contains a reference value given as the value of the upper level of reference values for a given protein marker in the population of healthy people, to which its concentration in the test subject's serum is referenced, allowing the determination of the following protein markers: DRG - digit 21-1, IBL-hCRP, DRG-NSE, NT-CEA, NT-CA125, USCN-SCCA1, h_tPA, S-100, NT-CA19-9.

PL406987A 2014-01-29 2014-01-29 Profile of blood protein markers as the test for detecting lung cancer PL230661B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PL406987A PL230661B1 (en) 2014-01-29 2014-01-29 Profile of blood protein markers as the test for detecting lung cancer
PCT/PL2015/000009 WO2015115922A1 (en) 2014-01-29 2015-01-29 A profile of blood protein markers as a test for the detection of lung cancer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL406987A PL230661B1 (en) 2014-01-29 2014-01-29 Profile of blood protein markers as the test for detecting lung cancer

Publications (2)

Publication Number Publication Date
PL406987A1 true PL406987A1 (en) 2015-08-03
PL230661B1 PL230661B1 (en) 2018-11-30

Family

ID=52633562

Family Applications (1)

Application Number Title Priority Date Filing Date
PL406987A PL230661B1 (en) 2014-01-29 2014-01-29 Profile of blood protein markers as the test for detecting lung cancer

Country Status (2)

Country Link
PL (1) PL230661B1 (en)
WO (1) WO2015115922A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023531860A (en) * 2020-04-28 2023-07-26 ルクセンブルク インスティテュート オブ ヘルス（エルアイエイチ） Biomarkers for lung cancer detection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007065463A1 (en) * 2005-12-09 2007-06-14 Indivumed Gmbh USE OF C3a AND DERIVATIVES THEREOF AS A BIOMARKER FOR BENIGN LUNG TISSUE ALTERATIONS AND MALIGN LUNG TUMORS, METHOD FOR DETECTION AND TEST SYSTEM
ES2372442T3 (en) * 2007-12-10 2012-01-19 F. Hoffmann-La Roche Ag SEPRASA AS A MARKER FOR CANCER.
US10815517B2 (en) * 2009-04-28 2020-10-27 Roche Diagnostics Operations, Inc. Use of DPPIV/seprase as a marker for cancer
US20120178111A1 (en) * 2009-09-23 2012-07-12 Diamandis Eleftherios P Methods and compositions for the detection of lung cancers

Also Published As

Publication number Publication date
PL230661B1 (en) 2018-11-30
WO2015115922A1 (en) 2015-08-06

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