[go: up one dir, main page]

PL3565526T3 - Topical detomidine formulations - Google Patents

Topical detomidine formulations

Info

Publication number
PL3565526T3
PL3565526T3 PL18701853.6T PL18701853T PL3565526T3 PL 3565526 T3 PL3565526 T3 PL 3565526T3 PL 18701853 T PL18701853 T PL 18701853T PL 3565526 T3 PL3565526 T3 PL 3565526T3
Authority
PL
Poland
Prior art keywords
detomidine
topical
formulations
topical detomidine
detomidine formulations
Prior art date
Application number
PL18701853.6T
Other languages
Polish (pl)
Inventor
Omer Tsipori
Mark ZAMANSKY
Original Assignee
Clexio Biosciences Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clexio Biosciences Ltd. filed Critical Clexio Biosciences Ltd.
Publication of PL3565526T3 publication Critical patent/PL3565526T3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41681,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/4174Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL18701853.6T 2017-01-06 2018-01-05 Topical detomidine formulations PL3565526T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762443174P 2017-01-06 2017-01-06
PCT/US2018/012579 WO2018129313A1 (en) 2017-01-06 2018-01-05 Topical detomidine formulations

Publications (1)

Publication Number Publication Date
PL3565526T3 true PL3565526T3 (en) 2024-09-09

Family

ID=61054537

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18701853.6T PL3565526T3 (en) 2017-01-06 2018-01-05 Topical detomidine formulations

Country Status (15)

Country Link
US (2) US20190343805A1 (en)
EP (1) EP3565526B1 (en)
JP (1) JP2020505322A (en)
KR (1) KR20190110561A (en)
CN (1) CN110114059A (en)
AU (1) AU2018205217B2 (en)
BR (1) BR112019011961A2 (en)
CA (1) CA3049389A1 (en)
DK (1) DK3565526T3 (en)
ES (1) ES2982022T3 (en)
HU (1) HUE068070T2 (en)
IL (1) IL266448B2 (en)
MX (1) MX382949B (en)
PL (1) PL3565526T3 (en)
WO (1) WO2018129313A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20210137830A1 (en) * 2018-07-11 2021-05-13 Clexio Biosciences Ltd. Topical detomidine formulations
US20210323929A1 (en) * 2018-07-18 2021-10-21 Clexio Biosciences Ltd. Purified Detomidine, Process of Preparing and Methods of Use
US20220211672A1 (en) 2019-05-01 2022-07-07 Clexio Biosciences Ltd. Methods of treating pruritus
KR20220002950A (en) 2019-05-01 2022-01-07 클렉시오 바이오사이언시스 리미티드 How to treat pruritus

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10256774A1 (en) * 2002-12-05 2004-06-24 Lts Lohmann Therapie-Systeme Ag Medicament for transmucosal or transdermal drug administration, containing combination of monoterpene and polyol, e.g. menthol and propanediol, as resorption improvers
FI20041425A0 (en) * 2004-11-05 2004-11-05 Orion Corp Transmucosal veterinary composition
EP2558101A4 (en) * 2010-04-15 2013-09-18 Univ Mcgill TOPICAL PAIN TREATMENTS
WO2013076160A1 (en) * 2011-11-21 2013-05-30 Université Libre de Bruxelles Sustained release formulations useful in the treatment of diseases
EP2803668A1 (en) * 2013-05-17 2014-11-19 Boehringer Ingelheim International Gmbh Novel (cyano-dimethyl-methyl)-isoxazoles and -[1,3,4]thiadiazoles
CA2921221A1 (en) * 2013-08-14 2015-02-19 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for controlling pain
US20150057351A1 (en) * 2013-08-22 2015-02-26 Sucampo Ag Method for treating neuropathic pain

Also Published As

Publication number Publication date
BR112019011961A2 (en) 2019-11-05
DK3565526T3 (en) 2024-05-13
CN110114059A (en) 2019-08-09
JP2020505322A (en) 2020-02-20
HUE068070T2 (en) 2024-12-28
EP3565526A1 (en) 2019-11-13
ES2982022T3 (en) 2024-10-14
IL266448A (en) 2019-06-30
AU2018205217B2 (en) 2023-11-09
IL266448B2 (en) 2023-11-01
KR20190110561A (en) 2019-09-30
US20190343805A1 (en) 2019-11-14
IL266448B1 (en) 2023-07-01
CA3049389A1 (en) 2018-07-12
EP3565526B1 (en) 2024-04-17
WO2018129313A1 (en) 2018-07-12
AU2018205217A1 (en) 2019-05-23
MX382949B (en) 2025-03-13
US20230172909A1 (en) 2023-06-08
MX2019008115A (en) 2019-10-24

Similar Documents

Publication Publication Date Title
IL289084A (en) Cannabinoid formulations
SG11202002653UA (en) Formulations
SG11202006782YA (en) Topical formulations comprising tofacitinib
IL269630A (en) Niraparib formulations
IL273282A (en) Niraparib formulations
IL269621A (en) Niraparib formulations
EP3302437A4 (en) Stable cannabinoid formulations
ZA201904704B (en) Topical cyclosporine-containing formulations and uses thereof
SG11201911318SA (en) Moisturizing topical preparation
IL279284A (en) Topical detomidine formulations
EP3145549A4 (en) Topical formulations and uses thereof
SG11202000615VA (en) Topical composition
SG11201706938XA (en) Topical formulation
IL268583A (en) Topical formulations and methods
IL266448A (en) Topical detomidine formulations
EP3383912A4 (en) Topical formulations
EP3349764A4 (en) Skin care compositions
IL272944A (en) Topical compositions
PL3373976T3 (en) Topical formulations and uses thereof
IL268374A (en) Topical composition
GB201713160D0 (en) Topical composition
GB201805338D0 (en) Cosmetic formulations
HK40111394A (en) Topical formulations and uses thereof
HK40112168A (en) Formulations
HK40114670A (en) Topical cyclosporine-containing formulations and uses thereof