PL2943493T3 - Związki terapeutyczne do leczenia zakażeń wirusowych - Google Patents
Związki terapeutyczne do leczenia zakażeń wirusowychInfo
- Publication number
- PL2943493T3 PL2943493T3 PL14701647T PL14701647T PL2943493T3 PL 2943493 T3 PL2943493 T3 PL 2943493T3 PL 14701647 T PL14701647 T PL 14701647T PL 14701647 T PL14701647 T PL 14701647T PL 2943493 T3 PL2943493 T3 PL 2943493T3
- Authority
- PL
- Poland
- Prior art keywords
- treatment
- viral infections
- therapeutic compounds
- therapeutic
- compounds
- Prior art date
Links
- 208000036142 Viral infection Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 230000009385 viral infection Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361750759P | 2013-01-09 | 2013-01-09 | |
EP14701647.1A EP2943493B1 (en) | 2013-01-09 | 2014-01-09 | Therapeutic compounds for the treatment of viral infections |
PCT/US2014/010937 WO2014110296A1 (en) | 2013-01-09 | 2014-01-09 | Therapeutic compounds for the treatment of viral infections |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2943493T3 true PL2943493T3 (pl) | 2017-12-29 |
Family
ID=50023885
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL14701647T PL2943493T3 (pl) | 2013-01-09 | 2014-01-09 | Związki terapeutyczne do leczenia zakażeń wirusowych |
Country Status (11)
Country | Link |
---|---|
US (1) | US9012441B2 (pl) |
EP (1) | EP2943493B1 (pl) |
JP (1) | JP5860197B1 (pl) |
AU (1) | AU2014205315B2 (pl) |
CA (1) | CA2897268C (pl) |
ES (1) | ES2642265T3 (pl) |
NZ (2) | NZ727792A (pl) |
PL (1) | PL2943493T3 (pl) |
PT (1) | PT2943493T (pl) |
SI (1) | SI2943493T1 (pl) |
WO (1) | WO2014110296A1 (pl) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2729448B1 (en) | 2011-07-06 | 2015-09-09 | Gilead Sciences, Inc. | Compounds for the treatment of hiv |
TW201443037A (zh) | 2013-01-09 | 2014-11-16 | Gilead Sciences Inc | 治療用化合物 |
JP5941598B2 (ja) | 2013-01-09 | 2016-06-29 | ギリアード サイエンシーズ, インコーポレイテッド | 5員ヘテロアリールおよびそれらの抗ウイルス剤としての使用 |
TWI706945B (zh) | 2013-03-01 | 2020-10-11 | 美商基利科學股份有限公司 | 供治療反轉錄病毒科病毒感染之治療性化合物 |
US10202353B2 (en) | 2014-02-28 | 2019-02-12 | Gilead Sciences, Inc. | Therapeutic compounds |
PT3186239T (pt) | 2014-08-29 | 2019-01-10 | Gilead Sciences Inc | Agentes antirretrovirais |
SG10202105371YA (en) | 2014-12-26 | 2021-07-29 | Univ Emory | N4-hydroxycytidine and derivatives and anti-viral uses related thereto |
SI3597646T1 (sl) | 2016-08-19 | 2023-10-30 | Gilead Sciences, Inc. | Terapevtske spojine, uporabne za profilaktično ali terapevtsko zdravljenje okužbe z virusom hiv |
UY37710A (es) | 2017-05-02 | 2018-11-30 | Viiv Healthcare Uk No 5 Ltd | Inhibidores de la replicación del virus de la inmunodeficiencia humana |
AR112412A1 (es) | 2017-08-17 | 2019-10-23 | Gilead Sciences Inc | Formas de sal de colina de un inhibidor de la cápside del vih |
AR112413A1 (es) | 2017-08-17 | 2019-10-23 | Gilead Sciences Inc | Formas sólidas de un inhibidor de la cápside del vih |
CA3082191C (en) | 2017-12-07 | 2021-09-21 | Emory University | N4-hydroxycytidine and derivatives and anti-viral uses related thereto |
CN111836805B (zh) | 2018-02-15 | 2023-07-14 | 吉利德科学公司 | 吡啶衍生物及其用于治疗hiv感染的用途 |
CN116854630A (zh) | 2018-02-16 | 2023-10-10 | 吉利德科学公司 | 用于制备可用于治疗逆转录病毒科病毒感染的治疗性化合物的方法和中间体 |
US11505543B2 (en) | 2018-04-11 | 2022-11-22 | VIIV Healthcare UK (No.5) Limited | 4-oxo-3,4-dihydroquinazoline compounds as inhibitors of human immunodeficiency virus replication |
CA3216031A1 (en) | 2018-07-16 | 2020-01-23 | Gilead Sciences, Inc. | Capsid inhibitors for the treatment of hiv |
US11958834B2 (en) | 2018-08-09 | 2024-04-16 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
JP7361766B2 (ja) | 2018-09-14 | 2023-10-16 | ヴィーブ ヘルスケア ユーケー(ナンバー5)リミテッド | ヒト免疫不全ウイルス複製の阻害剤 |
US11919897B2 (en) | 2018-09-20 | 2024-03-05 | Viiv Healthcare Uk (No. 5) Limited | Inhibitors of human immunodeficiency virus replication |
WO2020084491A1 (en) | 2018-10-24 | 2020-04-30 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
JP7398448B2 (ja) | 2018-10-24 | 2023-12-14 | ヴィーブ ヘルスケア ユーケー(ナンバー5)リミテッド | ヒト免疫不全ウイルス複製の阻害剤 |
PT3870575T (pt) | 2018-10-25 | 2023-05-12 | Viiv Healthcare Uk No 5 Ltd | Inibidores da replicação do vírus da imunodeficiência humana |
ES2969030T3 (es) | 2018-10-29 | 2024-05-16 | Viiv Healthcare Uk No 5 Ltd | Derivados de quinazolinil-indazol y su uso como inhibidores de replicación de virus de inmunodeficiencia humana |
WO2020095176A1 (en) | 2018-11-05 | 2020-05-14 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
EP3877387A1 (en) | 2018-11-05 | 2021-09-15 | ViiV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
CA3124783A1 (en) * | 2018-12-27 | 2020-07-02 | Taisho Pharmaceutical Co., Ltd. | Pyrazolo[1,5-a]pyrimidine macrocyclic compound |
UY38559A (es) | 2019-02-01 | 2020-07-31 | Viiv Healthcare Uk No 5 Ltd | Inhibidores de la replicación del virus de la inmunodeficiencia humana |
US20220211704A1 (en) | 2019-04-30 | 2022-07-07 | Viiv Healthcare Uk (No. 5) Limited | Inhibitors of human immunodeficiency virus replication |
FI3986561T3 (fi) | 2019-06-19 | 2024-05-02 | Viiv Healthcare Uk No 5 Ltd | Pyrido[2,3-d]pyrimidiinijohdannaisia ihmisen immuunikatoviruksen replikaation estäjinä |
EP4038068A1 (en) | 2019-10-01 | 2022-08-10 | VIIV Healthcare UK (No.5) Limited | N-substituted-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl derivatives as inhibitors of the human immunodeficiency virus replication |
WO2021064570A1 (en) | 2019-10-01 | 2021-04-08 | VIIV Healthcare UK (No.5) Limited | N-substututed-6-oxo-1,6-dihydropyrimidine-2-yl derivatives as inhibitors of the human immunodeficiency virus replication |
TW202128648A (zh) | 2019-10-04 | 2021-08-01 | 英商Viiv醫療保健英國(No 5)有限公司 | 人類免疫不全病毒複製之抑制劑 |
JP2022551691A (ja) | 2019-10-08 | 2022-12-13 | ビーブ、ヘルスケア、ユーケー、(ナンバー5)、リミテッド | ヒト免疫不全ウイルスの複製阻害剤 |
TWI854067B (zh) | 2019-11-26 | 2024-09-01 | 美商基利科學股份有限公司 | 預防hiv之蛋白殼抑制劑 |
EP4066839A4 (en) | 2019-11-28 | 2023-12-27 | Shionogi & Co., Ltd | PROPHYLACTIC AND THERAPEUTIC PHARMACEUTICAL AGENT FOR HIV INFECTIOUS DISEASES, CHARACTERIZED IN THAT IT COMPRISES A COMBINATION OF AN INTEGRASE INHIBITOR AND AN ANTI-HIV AGENT |
US20230106880A1 (en) | 2020-03-06 | 2023-04-06 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
MX2022011016A (es) | 2020-03-06 | 2022-11-30 | Viiv Healthcare Uk No 5 Ltd | Inhibidores de la replicacion del virus de inmunodeficiencia humana. |
WO2021209900A1 (en) | 2020-04-15 | 2021-10-21 | VIIV Healthcare UK (No.5) Limited | Inhibitors of human immunodeficiency virus replication |
EP4172157A1 (en) | 2020-06-25 | 2023-05-03 | Gilead Sciences, Inc. | Capsid inhibitors for the treatment of hiv |
TW202412779A (zh) | 2021-12-03 | 2024-04-01 | 美商基利科學股份有限公司 | 用於hiv病毒感染之治療性化合物 |
EP4440700A1 (en) | 2021-12-03 | 2024-10-09 | Gilead Sciences, Inc. | Therapeutic compounds for hiv virus infection |
TW202515516A (zh) | 2023-06-15 | 2025-04-16 | 英商Viiv醫療保健英國(No 5)有限公司 | 用於製備化合物之方法及中間物 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0302957A2 (hu) * | 2000-04-19 | 2003-12-29 | Schering Corporation | Hepatitis C vírus alkil- és aril-alanin P2 csoportokat tartalmazó makrociklusos NS-3 szerin proteáz inhibitorai |
US8513186B2 (en) * | 2007-06-29 | 2013-08-20 | Gilead Sciences, Inc. | Antiviral compounds |
JP5433573B2 (ja) * | 2007-07-19 | 2014-03-05 | イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・エルレ・エルレ | 抗ウイルス剤としての大環状化合物 |
CA2707418C (en) | 2007-11-16 | 2013-11-19 | Boehringer Ingelheim International Gmbh | Inhibitors of human immunodeficiency virus replication |
US8338441B2 (en) | 2009-05-15 | 2012-12-25 | Gilead Sciences, Inc. | Inhibitors of human immunodeficiency virus replication |
US20130165489A1 (en) | 2010-05-03 | 2013-06-27 | The Trustees Of The University Of Pennsylvania | Small Molecule Modulators of HIV-1 Capsid Stability and Methods Thereof |
PT2588450T (pt) | 2010-07-02 | 2017-08-03 | Gilead Sciences Inc | Derivados do ácido naft-2-ilacético para tratamento da sida |
CA2802492C (en) | 2010-07-02 | 2018-10-16 | Gilead Sciences, Inc. | 2-quinolinyl-acetic acid derivatives as hiv antiviral compounds |
KR20140027295A (ko) | 2011-04-21 | 2014-03-06 | 길리애드 사이언시즈, 인코포레이티드 | 벤조티아졸 화합물 및 이들의 약학적 용도 |
EP2729448B1 (en) | 2011-07-06 | 2015-09-09 | Gilead Sciences, Inc. | Compounds for the treatment of hiv |
CN102863512B (zh) | 2011-07-07 | 2016-04-20 | 上海泓博智源医药技术有限公司 | 抗病毒化合物 |
UY34750A (es) | 2012-04-20 | 2013-11-29 | Gilead Sciences Inc | ?compuestos para el tratamiento del hiv, composiciones,métodos de preparación, intermediarios y métodos terapéuticos?. |
GB201213087D0 (en) | 2012-07-24 | 2012-09-05 | Medical Res Council | Inhibition of HIV-1 infection |
TW201443037A (zh) | 2013-01-09 | 2014-11-16 | Gilead Sciences Inc | 治療用化合物 |
JP5941598B2 (ja) | 2013-01-09 | 2016-06-29 | ギリアード サイエンシーズ, インコーポレイテッド | 5員ヘテロアリールおよびそれらの抗ウイルス剤としての使用 |
-
2014
- 2014-01-09 NZ NZ727792A patent/NZ727792A/en not_active IP Right Cessation
- 2014-01-09 WO PCT/US2014/010937 patent/WO2014110296A1/en active Application Filing
- 2014-01-09 NZ NZ631726A patent/NZ631726A/en not_active IP Right Cessation
- 2014-01-09 PL PL14701647T patent/PL2943493T3/pl unknown
- 2014-01-09 CA CA2897268A patent/CA2897268C/en not_active Expired - Fee Related
- 2014-01-09 US US14/151,762 patent/US9012441B2/en active Active
- 2014-01-09 ES ES14701647.1T patent/ES2642265T3/es active Active
- 2014-01-09 EP EP14701647.1A patent/EP2943493B1/en active Active
- 2014-01-09 JP JP2015551872A patent/JP5860197B1/ja not_active Expired - Fee Related
- 2014-01-09 AU AU2014205315A patent/AU2014205315B2/en not_active Ceased
- 2014-01-09 PT PT147016471T patent/PT2943493T/pt unknown
- 2014-01-09 SI SI201430412T patent/SI2943493T1/sl unknown
Also Published As
Publication number | Publication date |
---|---|
ES2642265T3 (es) | 2017-11-16 |
JP5860197B1 (ja) | 2016-02-16 |
AU2014205315B2 (en) | 2016-11-17 |
NZ727792A (en) | 2018-04-27 |
AU2014205315A1 (en) | 2015-07-16 |
CA2897268C (en) | 2018-12-04 |
PT2943493T (pt) | 2017-10-23 |
JP2016508150A (ja) | 2016-03-17 |
HK1216421A1 (en) | 2016-11-11 |
US9012441B2 (en) | 2015-04-21 |
EP2943493A1 (en) | 2015-11-18 |
EP2943493B1 (en) | 2017-08-02 |
US20140221417A1 (en) | 2014-08-07 |
NZ631726A (en) | 2017-01-27 |
WO2014110296A1 (en) | 2014-07-17 |
CA2897268A1 (en) | 2014-07-17 |
SI2943493T1 (sl) | 2017-11-30 |
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