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PL2943493T3 - Związki terapeutyczne do leczenia zakażeń wirusowych - Google Patents

Związki terapeutyczne do leczenia zakażeń wirusowych

Info

Publication number
PL2943493T3
PL2943493T3 PL14701647T PL14701647T PL2943493T3 PL 2943493 T3 PL2943493 T3 PL 2943493T3 PL 14701647 T PL14701647 T PL 14701647T PL 14701647 T PL14701647 T PL 14701647T PL 2943493 T3 PL2943493 T3 PL 2943493T3
Authority
PL
Poland
Prior art keywords
treatment
viral infections
therapeutic compounds
therapeutic
compounds
Prior art date
Application number
PL14701647T
Other languages
English (en)
Inventor
Steven S. Bondy
Carina E. Cannizzaro
Chien-Hung Chou
Yunfeng Eric Hu
John O. Link
Qi Liu
Scott D. Schroeder
Winston C. Tse
Jennifer R. Zhang
Original Assignee
Gilead Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences, Inc. filed Critical Gilead Sciences, Inc.
Publication of PL2943493T3 publication Critical patent/PL2943493T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL14701647T 2013-01-09 2014-01-09 Związki terapeutyczne do leczenia zakażeń wirusowych PL2943493T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361750759P 2013-01-09 2013-01-09
EP14701647.1A EP2943493B1 (en) 2013-01-09 2014-01-09 Therapeutic compounds for the treatment of viral infections
PCT/US2014/010937 WO2014110296A1 (en) 2013-01-09 2014-01-09 Therapeutic compounds for the treatment of viral infections

Publications (1)

Publication Number Publication Date
PL2943493T3 true PL2943493T3 (pl) 2017-12-29

Family

ID=50023885

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14701647T PL2943493T3 (pl) 2013-01-09 2014-01-09 Związki terapeutyczne do leczenia zakażeń wirusowych

Country Status (11)

Country Link
US (1) US9012441B2 (pl)
EP (1) EP2943493B1 (pl)
JP (1) JP5860197B1 (pl)
AU (1) AU2014205315B2 (pl)
CA (1) CA2897268C (pl)
ES (1) ES2642265T3 (pl)
NZ (2) NZ727792A (pl)
PL (1) PL2943493T3 (pl)
PT (1) PT2943493T (pl)
SI (1) SI2943493T1 (pl)
WO (1) WO2014110296A1 (pl)

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US10202353B2 (en) 2014-02-28 2019-02-12 Gilead Sciences, Inc. Therapeutic compounds
PT3186239T (pt) 2014-08-29 2019-01-10 Gilead Sciences Inc Agentes antirretrovirais
SG10202105371YA (en) 2014-12-26 2021-07-29 Univ Emory N4-hydroxycytidine and derivatives and anti-viral uses related thereto
SI3597646T1 (sl) 2016-08-19 2023-10-30 Gilead Sciences, Inc. Terapevtske spojine, uporabne za profilaktično ali terapevtsko zdravljenje okužbe z virusom hiv
UY37710A (es) 2017-05-02 2018-11-30 Viiv Healthcare Uk No 5 Ltd Inhibidores de la replicación del virus de la inmunodeficiencia humana
AR112412A1 (es) 2017-08-17 2019-10-23 Gilead Sciences Inc Formas de sal de colina de un inhibidor de la cápside del vih
AR112413A1 (es) 2017-08-17 2019-10-23 Gilead Sciences Inc Formas sólidas de un inhibidor de la cápside del vih
CA3082191C (en) 2017-12-07 2021-09-21 Emory University N4-hydroxycytidine and derivatives and anti-viral uses related thereto
CN111836805B (zh) 2018-02-15 2023-07-14 吉利德科学公司 吡啶衍生物及其用于治疗hiv感染的用途
CN116854630A (zh) 2018-02-16 2023-10-10 吉利德科学公司 用于制备可用于治疗逆转录病毒科病毒感染的治疗性化合物的方法和中间体
US11505543B2 (en) 2018-04-11 2022-11-22 VIIV Healthcare UK (No.5) Limited 4-oxo-3,4-dihydroquinazoline compounds as inhibitors of human immunodeficiency virus replication
CA3216031A1 (en) 2018-07-16 2020-01-23 Gilead Sciences, Inc. Capsid inhibitors for the treatment of hiv
US11958834B2 (en) 2018-08-09 2024-04-16 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
JP7361766B2 (ja) 2018-09-14 2023-10-16 ヴィーブ ヘルスケア ユーケー(ナンバー5)リミテッド ヒト免疫不全ウイルス複製の阻害剤
US11919897B2 (en) 2018-09-20 2024-03-05 Viiv Healthcare Uk (No. 5) Limited Inhibitors of human immunodeficiency virus replication
WO2020084491A1 (en) 2018-10-24 2020-04-30 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
JP7398448B2 (ja) 2018-10-24 2023-12-14 ヴィーブ ヘルスケア ユーケー(ナンバー5)リミテッド ヒト免疫不全ウイルス複製の阻害剤
PT3870575T (pt) 2018-10-25 2023-05-12 Viiv Healthcare Uk No 5 Ltd Inibidores da replicação do vírus da imunodeficiência humana
ES2969030T3 (es) 2018-10-29 2024-05-16 Viiv Healthcare Uk No 5 Ltd Derivados de quinazolinil-indazol y su uso como inhibidores de replicación de virus de inmunodeficiencia humana
WO2020095176A1 (en) 2018-11-05 2020-05-14 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
EP3877387A1 (en) 2018-11-05 2021-09-15 ViiV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
CA3124783A1 (en) * 2018-12-27 2020-07-02 Taisho Pharmaceutical Co., Ltd. Pyrazolo[1,5-a]pyrimidine macrocyclic compound
UY38559A (es) 2019-02-01 2020-07-31 Viiv Healthcare Uk No 5 Ltd Inhibidores de la replicación del virus de la inmunodeficiencia humana
US20220211704A1 (en) 2019-04-30 2022-07-07 Viiv Healthcare Uk (No. 5) Limited Inhibitors of human immunodeficiency virus replication
FI3986561T3 (fi) 2019-06-19 2024-05-02 Viiv Healthcare Uk No 5 Ltd Pyrido[2,3-d]pyrimidiinijohdannaisia ihmisen immuunikatoviruksen replikaation estäjinä
EP4038068A1 (en) 2019-10-01 2022-08-10 VIIV Healthcare UK (No.5) Limited N-substituted-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl derivatives as inhibitors of the human immunodeficiency virus replication
WO2021064570A1 (en) 2019-10-01 2021-04-08 VIIV Healthcare UK (No.5) Limited N-substututed-6-oxo-1,6-dihydropyrimidine-2-yl derivatives as inhibitors of the human immunodeficiency virus replication
TW202128648A (zh) 2019-10-04 2021-08-01 英商Viiv醫療保健英國(No 5)有限公司 人類免疫不全病毒複製之抑制劑
JP2022551691A (ja) 2019-10-08 2022-12-13 ビーブ、ヘルスケア、ユーケー、(ナンバー5)、リミテッド ヒト免疫不全ウイルスの複製阻害剤
TWI854067B (zh) 2019-11-26 2024-09-01 美商基利科學股份有限公司 預防hiv之蛋白殼抑制劑
EP4066839A4 (en) 2019-11-28 2023-12-27 Shionogi & Co., Ltd PROPHYLACTIC AND THERAPEUTIC PHARMACEUTICAL AGENT FOR HIV INFECTIOUS DISEASES, CHARACTERIZED IN THAT IT COMPRISES A COMBINATION OF AN INTEGRASE INHIBITOR AND AN ANTI-HIV AGENT
US20230106880A1 (en) 2020-03-06 2023-04-06 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
MX2022011016A (es) 2020-03-06 2022-11-30 Viiv Healthcare Uk No 5 Ltd Inhibidores de la replicacion del virus de inmunodeficiencia humana.
WO2021209900A1 (en) 2020-04-15 2021-10-21 VIIV Healthcare UK (No.5) Limited Inhibitors of human immunodeficiency virus replication
EP4172157A1 (en) 2020-06-25 2023-05-03 Gilead Sciences, Inc. Capsid inhibitors for the treatment of hiv
TW202412779A (zh) 2021-12-03 2024-04-01 美商基利科學股份有限公司 用於hiv病毒感染之治療性化合物
EP4440700A1 (en) 2021-12-03 2024-10-09 Gilead Sciences, Inc. Therapeutic compounds for hiv virus infection
TW202515516A (zh) 2023-06-15 2025-04-16 英商Viiv醫療保健英國(No 5)有限公司 用於製備化合物之方法及中間物

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US8513186B2 (en) * 2007-06-29 2013-08-20 Gilead Sciences, Inc. Antiviral compounds
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CA2707418C (en) 2007-11-16 2013-11-19 Boehringer Ingelheim International Gmbh Inhibitors of human immunodeficiency virus replication
US8338441B2 (en) 2009-05-15 2012-12-25 Gilead Sciences, Inc. Inhibitors of human immunodeficiency virus replication
US20130165489A1 (en) 2010-05-03 2013-06-27 The Trustees Of The University Of Pennsylvania Small Molecule Modulators of HIV-1 Capsid Stability and Methods Thereof
PT2588450T (pt) 2010-07-02 2017-08-03 Gilead Sciences Inc Derivados do ácido naft-2-ilacético para tratamento da sida
CA2802492C (en) 2010-07-02 2018-10-16 Gilead Sciences, Inc. 2-quinolinyl-acetic acid derivatives as hiv antiviral compounds
KR20140027295A (ko) 2011-04-21 2014-03-06 길리애드 사이언시즈, 인코포레이티드 벤조티아졸 화합물 및 이들의 약학적 용도
EP2729448B1 (en) 2011-07-06 2015-09-09 Gilead Sciences, Inc. Compounds for the treatment of hiv
CN102863512B (zh) 2011-07-07 2016-04-20 上海泓博智源医药技术有限公司 抗病毒化合物
UY34750A (es) 2012-04-20 2013-11-29 Gilead Sciences Inc ?compuestos para el tratamiento del hiv, composiciones,métodos de preparación, intermediarios y métodos terapéuticos?.
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JP5941598B2 (ja) 2013-01-09 2016-06-29 ギリアード サイエンシーズ, インコーポレイテッド 5員ヘテロアリールおよびそれらの抗ウイルス剤としての使用

Also Published As

Publication number Publication date
ES2642265T3 (es) 2017-11-16
JP5860197B1 (ja) 2016-02-16
AU2014205315B2 (en) 2016-11-17
NZ727792A (en) 2018-04-27
AU2014205315A1 (en) 2015-07-16
CA2897268C (en) 2018-12-04
PT2943493T (pt) 2017-10-23
JP2016508150A (ja) 2016-03-17
HK1216421A1 (en) 2016-11-11
US9012441B2 (en) 2015-04-21
EP2943493A1 (en) 2015-11-18
EP2943493B1 (en) 2017-08-02
US20140221417A1 (en) 2014-08-07
NZ631726A (en) 2017-01-27
WO2014110296A1 (en) 2014-07-17
CA2897268A1 (en) 2014-07-17
SI2943493T1 (sl) 2017-11-30

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