[go: up one dir, main page]

PL2790687T3 - Modulatory trpc4 do stosowania w leczeniu lub zapobieganiu bólowi - Google Patents

Modulatory trpc4 do stosowania w leczeniu lub zapobieganiu bólowi

Info

Publication number
PL2790687T3
PL2790687T3 PL12806318T PL12806318T PL2790687T3 PL 2790687 T3 PL2790687 T3 PL 2790687T3 PL 12806318 T PL12806318 T PL 12806318T PL 12806318 T PL12806318 T PL 12806318T PL 2790687 T3 PL2790687 T3 PL 2790687T3
Authority
PL
Poland
Prior art keywords
trpc4
modulators
pain
prevention
treatment
Prior art date
Application number
PL12806318T
Other languages
English (en)
Inventor
Eric M. Ostertag
John Stuart Crawford
Original Assignee
Poseida Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Poseida Therapeutics, Inc. filed Critical Poseida Therapeutics, Inc.
Publication of PL2790687T3 publication Critical patent/PL2790687T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
PL12806318T 2011-12-16 2012-12-14 Modulatory trpc4 do stosowania w leczeniu lub zapobieganiu bólowi PL2790687T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161576619P 2011-12-16 2011-12-16
PCT/US2012/069753 WO2013090722A1 (en) 2011-12-16 2012-12-14 Trpc4 modulators for use in the treatment or prevention of pain
EP12806318.7A EP2790687B1 (en) 2011-12-16 2012-12-14 Trpc4 modulators for use in the treatment or prevention of pain

Publications (1)

Publication Number Publication Date
PL2790687T3 true PL2790687T3 (pl) 2019-03-29

Family

ID=47430150

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12806318T PL2790687T3 (pl) 2011-12-16 2012-12-14 Modulatory trpc4 do stosowania w leczeniu lub zapobieganiu bólowi

Country Status (18)

Country Link
US (2) US10131634B2 (pl)
EP (2) EP2790687B1 (pl)
JP (3) JP2015500345A (pl)
AU (2) AU2012352083B2 (pl)
CA (1) CA2859283C (pl)
CY (1) CY1121293T1 (pl)
DK (1) DK2790687T3 (pl)
ES (1) ES2692546T3 (pl)
HR (1) HRP20181746T1 (pl)
HU (1) HUE041294T2 (pl)
LT (1) LT2790687T (pl)
PL (1) PL2790687T3 (pl)
PT (1) PT2790687T (pl)
RS (1) RS57919B1 (pl)
SI (1) SI2790687T1 (pl)
SM (1) SMT201800613T1 (pl)
TR (1) TR201815535T4 (pl)
WO (1) WO2013090722A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013090722A1 (en) * 2011-12-16 2013-06-20 Transposagen Biopharmaceuticals, Inc. Trpc4 modulators for use in the treatment or prevention of pain
CN114096247B (zh) * 2019-04-11 2024-04-26 帝人制药株式会社 苯并咪唑衍生物及其用途

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399216A (en) 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
HU198036B (en) * 1983-08-22 1989-07-28 Hoechst Roussel Pharma Process for production of derivatives of 3-piperidil-/1h/-indasole and medical preparatives containing them
US5506337A (en) 1985-03-15 1996-04-09 Antivirals Inc. Morpholino-subunit combinatorial library and method
US5010175A (en) 1988-05-02 1991-04-23 The Regents Of The University Of California General method for producing and selecting peptides with specific properties
IE66205B1 (en) 1990-06-14 1995-12-13 Paul A Bartlett Polypeptide analogs
US5650489A (en) 1990-07-02 1997-07-22 The Arizona Board Of Regents Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
WO1992021029A1 (en) 1991-05-10 1992-11-26 Genentech, Inc. Selecting ligand agonists and antagonists
US5573905A (en) 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5288514A (en) 1992-09-14 1994-02-22 The Regents Of The University Of California Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support
US5519134A (en) 1994-01-11 1996-05-21 Isis Pharmaceuticals, Inc. Pyrrolidine-containing monomers and oligomers
US5593853A (en) 1994-02-09 1997-01-14 Martek Corporation Generation and screening of synthetic drug libraries
US5539083A (en) 1994-02-23 1996-07-23 Isis Pharmaceuticals, Inc. Peptide nucleic acid combinatorial libraries and improved methods of synthesis
US5525735A (en) 1994-06-22 1996-06-11 Affymax Technologies Nv Methods for synthesizing diverse collections of pyrrolidine compounds
US5549974A (en) 1994-06-23 1996-08-27 Affymax Technologies Nv Methods for the solid phase synthesis of thiazolidinones, metathiazanones, and derivatives thereof
US5656449A (en) * 1995-03-06 1997-08-12 Molecular Probes, Inc. Neutral unsymmetrical cyanine dyes
ATE483733T1 (de) 1995-06-14 2010-10-15 Univ California Hochaffine humane antikörper gegen tumorantigene
US5569588A (en) 1995-08-09 1996-10-29 The Regents Of The University Of California Methods for drug screening
DK0974111T3 (da) 1997-04-11 2003-04-22 California Inst Of Techn Apparat og metode til automatiseret design af proteiner
US6403312B1 (en) 1998-10-16 2002-06-11 Xencor Protein design automatic for protein libraries
WO2000064877A1 (en) * 1999-04-26 2000-11-02 Neurogen Corporation 2-aminoquinolinecarboxamides: neurokinin receptor ligands
US7375125B2 (en) 1999-08-04 2008-05-20 Ore Pharmaceuticals, Inc. Melanocortin-4 receptor binding compounds and methods of use thereof
AU7645700A (en) 1999-10-07 2001-05-10 Maxygen Aps Single-chain antagonist polypeptides
US20020072101A1 (en) 2000-01-21 2002-06-13 Gaughan Glen T. Novel human nucleic acid molecules and polypeptides encoding cation channels
IL155613A0 (en) 2000-12-01 2003-11-23 Bristol Myers Squibb Co Novel human nucleic acid molecules and polypeptides emcoding a novel human ion channel expressed in spinal cord and brain
US7223557B2 (en) 2001-05-22 2007-05-29 Bristol-Myers Squibb Company Polynucleotide encoding a TRP channel family member, TRP-PLIK2
EP1427408A4 (en) * 2001-09-17 2005-10-26 Bristol Myers Squibb Co CYCLIC HYDROXAMINE ACIDS AS INHIBITORS OF MATRIX METALLOPROTEINASES AND / OR TNF-a-CONVERTASE (TACE TNF-a-CONVERTING ENZYM)
PE20030701A1 (es) * 2001-12-20 2003-08-21 Schering Corp Compuestos para el tratamiento de trastornos inflamatorios
WO2003057843A2 (en) * 2001-12-31 2003-07-17 Algos Therapeutics, Inc. Methods and materials for modulating trpc4
US20050103029A1 (en) * 2002-01-15 2005-05-19 Keizou Kawahara Refrigerator having alarm device for alarming leakage of refrigerant
WO2004039463A1 (ja) * 2002-10-31 2004-05-13 Kunihiro Tamura グラヴィティ ルールを実感するゴルフクラブ
US7256200B2 (en) 2003-02-10 2007-08-14 The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois Method and composition for potentiating an oplate analgesic
KR100561646B1 (ko) * 2003-10-23 2006-03-20 엘지.필립스 엘시디 주식회사 표시 소자용 박막 트랜지스터 기판 및 그 제조 방법
WO2005087742A1 (en) * 2004-03-08 2005-09-22 Exelixis, Inc. Metabolic kinase modulators and methods of use as pesticides
US20070196866A1 (en) 2004-03-13 2007-08-23 Irm Llc Modulators of ion channel trpa1
US7524862B2 (en) 2004-04-14 2009-04-28 Boehringer Ingelheim International Gmbh Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds
DE102004017932A1 (de) * 2004-04-14 2005-11-03 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel
WO2007025613A2 (en) * 2005-07-15 2007-03-08 Laboratorios Del Dr. Esteve, S.A. Use of compounds binding to the sigma receptor for the treatment of diabetes-associated pain
CA2657702A1 (en) 2006-07-03 2008-01-10 Vereniging Voor Christelijk Hoger Onderwijs Wetenschappelijk Onderzoek E N Patieentenzorg Quinazolines and related heterocyclic comp0unds, and their therapeutic use
GB0615136D0 (en) 2006-07-29 2006-09-06 Univ Edinburgh Induction of analgesia in neuropathic pain
US20090131302A1 (en) 2007-04-11 2009-05-21 Pasricha Pankaj J Transient receptor potential vanilloid 1 and uses thereof
JP5241832B2 (ja) * 2007-06-27 2013-07-17 ドルビー ラボラトリーズ ライセンシング コーポレイション マルチメディアコンテンツの特定のためのシグネチャポインターを含む検索ツリーのインクレメンタル構造
EP2203411B1 (en) 2007-09-20 2016-01-06 Ramot at Tel-Aviv University Ltd. N-phenyl anthranilic acid derivatives and uses thereof
US8084616B2 (en) 2007-10-24 2011-12-27 Abbott Laboratories TRPV1 antagonists
US7998993B2 (en) 2007-10-25 2011-08-16 Abbott Laboratories TRPV1 antagonists
KR20090047637A (ko) 2007-11-08 2009-05-13 재단법인서울대학교산학협력재단 커큐민 또는 이의 약학적으로 허용가능한 염을유효성분으로 함유하는 통증 예방 및 치료용 조성물
AU2008344922A1 (en) 2007-12-18 2012-01-19 Glenmark Pharmaceuticals, S.A. Chromane derivatives as TRPV3 modulators
EP2219646A4 (en) * 2007-12-21 2010-12-22 Univ Rochester PROCESS FOR EXTENDING THE LIFE OF EUKARYOTIC ORGANISMS
CN102016909A (zh) * 2008-12-19 2011-04-13 松下电器产业株式会社 图像检索装置以及图像检索方法
WO2011022634A2 (en) * 2009-08-20 2011-02-24 Transposagen Biopharmaceuticals, Inc. Genetically modified rat models for pain
US20120148604A1 (en) 2009-08-20 2012-06-14 Transposagen Biopharmaceuticals, Inc. Trp inhibitors and uses thereof
DE102009046649A1 (de) 2009-11-12 2011-05-19 Robert Bosch Gmbh Klimakompressor für ein Fahrzeug, Fahrzeug
AU2011253003B2 (en) 2010-05-13 2014-05-01 Amgen Inc. Heteroaryloxyheterocyclyl compounds as PDE10 inhibitors
WO2013090722A1 (en) * 2011-12-16 2013-06-20 Transposagen Biopharmaceuticals, Inc. Trpc4 modulators for use in the treatment or prevention of pain

Also Published As

Publication number Publication date
CA2859283A1 (en) 2013-06-20
DK2790687T3 (en) 2018-11-19
JP2015500345A (ja) 2015-01-05
US20190135759A1 (en) 2019-05-09
JP6858808B2 (ja) 2021-04-14
AU2018202172A1 (en) 2018-04-26
AU2012352083B2 (en) 2018-01-04
RS57919B1 (sr) 2019-01-31
LT2790687T (lt) 2018-12-10
EP2790687A1 (en) 2014-10-22
US20140329856A1 (en) 2014-11-06
HRP20181746T1 (hr) 2018-12-28
SI2790687T1 (sl) 2019-01-31
JP6534716B2 (ja) 2019-06-26
PT2790687T (pt) 2018-11-13
AU2018202172B2 (en) 2019-12-19
AU2012352083A1 (en) 2014-07-17
HUE041294T2 (hu) 2019-05-28
ES2692546T3 (es) 2018-12-04
TR201815535T4 (tr) 2018-11-21
WO2013090722A1 (en) 2013-06-20
EP3485889B1 (en) 2023-09-06
EP2790687B1 (en) 2018-08-29
SMT201800613T1 (it) 2019-01-11
CY1121293T1 (el) 2020-05-29
CA2859283C (en) 2021-03-09
EP3485889A1 (en) 2019-05-22
JP2018030875A (ja) 2018-03-01
US10131634B2 (en) 2018-11-20
JP2019135271A (ja) 2019-08-15

Similar Documents

Publication Publication Date Title
IL261768B (en) Devices and methods for tissue treatment
EP2836270A4 (en) SYSTEMS AND METHODS RELATED TO THE TREATMENT OF BACK PAIN
IL229474A0 (en) Cannabinoids for use in the treatment of neuropathic pain
HK1184370A1 (zh) 用於治療疼痛的藥物組合
ZA201502290B (en) 2-phenyl-5-heterocyclyl-tetrahydro-2h-pyran-3-amine compounds for use in the treatment of diabetes and ist associated disorders
ZA201408055B (en) Compositions and methods for the treatment of local pain
HK1210585A1 (en) Alpha-1-microglobulin for use in the treatment of mitochondria- related diseases -1
HRP20181761T1 (hr) Novi pripravak alfentanila za liječenje akutne boli
HK1203054A1 (en) Dinuceloside polyphosphates for the treatment of pain
ZA201501503B (en) Bio-inoculant and use thereof for treatment of effluents
ZA201307058B (en) Use of polyaminoisoprenyl derrivatives in antobiotic or antisertic treatment
HRP20181746T1 (hr) Trpc4 modulatori za uporabu u liječenju ili prevenciji bola
HK1214771A1 (zh) 用於治療皮膚病的製劑
LT2863932T (lt) Kompozicija, skirta naudoti limfedemos gydymui
AU2012900796A0 (en) Pain treatment
GB201013068D0 (en) Liquid treatment
ZA201303790B (en) Formulation useful for treating pain and/or inflammation
AU2012903356A0 (en) Improvements in Medical Treatment