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PL2528599T4 - Nowy polimorf chlorowodorku estru (6-dwumetyloamino metylo-2-naftalenylowego) kwasu (4-hydroksykarbamoilo-fenylo)-karbamowego - Google Patents

Nowy polimorf chlorowodorku estru (6-dwumetyloamino metylo-2-naftalenylowego) kwasu (4-hydroksykarbamoilo-fenylo)-karbamowego

Info

Publication number
PL2528599T4
PL2528599T4 PL10796492T PL10796492T PL2528599T4 PL 2528599 T4 PL2528599 T4 PL 2528599T4 PL 10796492 T PL10796492 T PL 10796492T PL 10796492 T PL10796492 T PL 10796492T PL 2528599 T4 PL2528599 T4 PL 2528599T4
Authority
PL
Poland
Prior art keywords
hydroxycarbamoyl
naphthalenyl
hydrochloride
phenyl
ester
Prior art date
Application number
PL10796492T
Other languages
English (en)
Other versions
PL2528599T3 (pl
Inventor
Stefano Turchetta
Maurizio Zenoni
Original Assignee
Chemi Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemi Spa filed Critical Chemi Spa
Publication of PL2528599T3 publication Critical patent/PL2528599T3/pl
Publication of PL2528599T4 publication Critical patent/PL2528599T4/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C07C271/28Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PL10796492T 2010-01-28 2010-12-03 Nowy polimorf chlorowodorku estru (6-dwumetyloamino metylo-2-naftalenylowego) kwasu (4-hydroksykarbamoilo-fenylo)-karbamowego PL2528599T4 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI2010A000121A IT1397912B1 (it) 2010-01-28 2010-01-28 Nuovo polimorfo dell'estere 6-dietilamminometil-2-naftilico dell'acido 4-idrossicarbamoil-fenil-carbammico cloridrato.
EP10796492.6A EP2528599B1 (en) 2010-01-28 2010-12-03 Novel polymorph of the hydrochloride of the (4-hydroxycarbamoyl-phenyl)-carbamic acid (6-dimethylamino methyl-2-naphthalenyl) ester
PCT/IB2010/055560 WO2011092556A1 (en) 2010-01-28 2010-12-03 Novel polymorph of the hydrochloride of the (4-hydroxycarbamoyl-phenyl)-carbamic acid (6-dimethylamino methyl-2-naphtalenyl) ester

Publications (2)

Publication Number Publication Date
PL2528599T3 PL2528599T3 (pl) 2014-10-31
PL2528599T4 true PL2528599T4 (pl) 2014-11-28

Family

ID=42288805

Family Applications (1)

Application Number Title Priority Date Filing Date
PL10796492T PL2528599T4 (pl) 2010-01-28 2010-12-03 Nowy polimorf chlorowodorku estru (6-dwumetyloamino metylo-2-naftalenylowego) kwasu (4-hydroksykarbamoilo-fenylo)-karbamowego

Country Status (19)

Country Link
US (1) US8518988B2 (pl)
EP (1) EP2528599B1 (pl)
JP (1) JP2013518091A (pl)
KR (1) KR101723532B1 (pl)
CN (1) CN102665712B (pl)
AU (1) AU2010344330B2 (pl)
BR (1) BR112012018626B1 (pl)
CA (1) CA2780432C (pl)
CY (1) CY1115409T1 (pl)
DK (1) DK2528599T3 (pl)
ES (1) ES2489467T3 (pl)
HR (1) HRP20140610T1 (pl)
IT (1) IT1397912B1 (pl)
MX (1) MX2012008777A (pl)
PL (1) PL2528599T4 (pl)
PT (1) PT2528599E (pl)
RU (1) RU2552354C2 (pl)
SI (1) SI2528599T1 (pl)
WO (1) WO2011092556A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015512869A (ja) * 2012-02-03 2015-04-30 イタルファルマコ ソシエタ ペル アチオニItalfarmaco Societa Per Azioni 筋ジストロフィーの治療に用いられるジエチル−[6−(4−ヒドロキシカルバモイル−フェニル−カルバモイルオキシ−メチル)−ナフタレン−2−イル−メチル]−アンモニウムクロリド
ITUB20155193A1 (it) * 2015-11-03 2017-05-03 Italfarmaco Spa Sospensioni orali di Givinostat fisicamente e chimicamente stabili
IT201900003281A1 (it) 2019-03-06 2020-09-06 Chemi Spa Processo per preparare {6-[(dietilammino)metil]naftalen-2-il}metil [4-(idrossicarbamoil)fenil]carbammato ad elevata purezza

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3574185B2 (ja) * 1994-09-02 2004-10-06 小松屋化学株式会社 無水クエン酸トリマグネシウムおよびその製法
IT1283637B1 (it) * 1996-05-14 1998-04-23 Italfarmaco Spa Composti ad attivita' antinfiammatoria ed immunosoppressiva
WO1997046526A1 (en) * 1996-06-07 1997-12-11 Eisai Co., Ltd. Stable polymorphs of donepezil (1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine) hydrochloride and process for production
ITMI20030063A1 (it) * 2003-01-17 2004-07-18 Italfarmaco Spa Cloridrato monoidrato dell'estere (6-dietilamminometil-naftalen-2-il)metilico dell'acido (4-idrossicarbammoil-fenil)carbammico.
JP2008538581A (ja) * 2005-04-22 2008-10-30 ワイス {[(2r)−7−(2,6−ジクロロフェニル)−5−フルオロ−2,3−ジヒドロ−1−ベンゾフラン−2−イル]メチル}アミン塩酸塩の結晶形態
EP1805148A2 (en) * 2005-08-16 2007-07-11 Teva Pharmaceutical Industries Ltd. Crystalline rosuvastatin intermediate
KR100830003B1 (ko) * 2006-10-31 2008-05-15 씨제이제일제당 (주) 결정성 s-(-)-암로디핀 아디핀산 염 무수물 및 이의 제조방법
WO2009019205A1 (en) * 2007-08-03 2009-02-12 Boehringer Ingelheim International Gmbh Crystalline form of a dihydropteridione derivative

Also Published As

Publication number Publication date
CY1115409T1 (el) 2017-01-04
BR112012018626A8 (pt) 2017-12-19
CA2780432A1 (en) 2011-08-04
KR20120123259A (ko) 2012-11-08
PT2528599E (pt) 2014-07-18
HRP20140610T1 (hr) 2014-08-15
CA2780432C (en) 2017-02-21
PL2528599T3 (pl) 2014-10-31
HK1175699A1 (en) 2013-07-12
CN102665712A (zh) 2012-09-12
EP2528599B1 (en) 2014-05-21
BR112012018626B1 (pt) 2021-06-08
JP2013518091A (ja) 2013-05-20
WO2011092556A1 (en) 2011-08-04
RU2012134703A (ru) 2014-03-10
ES2489467T3 (es) 2014-09-02
CN102665712B (zh) 2013-10-16
AU2010344330B2 (en) 2014-11-13
IT1397912B1 (it) 2013-02-04
KR101723532B1 (ko) 2017-04-06
DK2528599T3 (da) 2014-06-30
BR112012018626A2 (pt) 2016-05-03
US8518988B2 (en) 2013-08-27
RU2552354C2 (ru) 2015-06-10
EP2528599A1 (en) 2012-12-05
AU2010344330A1 (en) 2012-05-24
SI2528599T1 (sl) 2014-09-30
US20120302633A1 (en) 2012-11-29
MX2012008777A (es) 2012-09-07
ITMI20100121A1 (it) 2011-07-29

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