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PL2346870T3 - Foliany znakowane fluorem-18 jako radioznaczniki pet - Google Patents

Foliany znakowane fluorem-18 jako radioznaczniki pet

Info

Publication number
PL2346870T3
PL2346870T3 PL09783938T PL09783938T PL2346870T3 PL 2346870 T3 PL2346870 T3 PL 2346870T3 PL 09783938 T PL09783938 T PL 09783938T PL 09783938 T PL09783938 T PL 09783938T PL 2346870 T3 PL2346870 T3 PL 2346870T3
Authority
PL
Poland
Prior art keywords
pet radiotracers
folates
labelled
labelled folates
radiotracers
Prior art date
Application number
PL09783938T
Other languages
English (en)
Inventor
Roger Schibli
Rudolf Moser
Cristina Magdalena Müller
Simon Mensah Ametamey
Tobias Ludwig Ross
Viola Groehn
Original Assignee
Merck & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Cie filed Critical Merck & Cie
Publication of PL2346870T3 publication Critical patent/PL2346870T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/02Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL09783938T 2008-10-10 2009-10-12 Foliany znakowane fluorem-18 jako radioznaczniki pet PL2346870T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08166356 2008-10-10
EP09783938.5A EP2346870B1 (en) 2008-10-10 2009-10-12 18f-labelled folates as pet radiotracers
PCT/EP2009/063258 WO2010040854A1 (en) 2008-10-10 2009-10-12 18f-labelled folates as pet radiotracers

Publications (1)

Publication Number Publication Date
PL2346870T3 true PL2346870T3 (pl) 2016-01-29

Family

ID=41397772

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09783938T PL2346870T3 (pl) 2008-10-10 2009-10-12 Foliany znakowane fluorem-18 jako radioznaczniki pet

Country Status (17)

Country Link
US (2) US20110286921A1 (pl)
EP (1) EP2346870B1 (pl)
JP (1) JP5730771B2 (pl)
KR (1) KR101756793B1 (pl)
CN (1) CN102177160B (pl)
AU (1) AU2009301042B2 (pl)
CA (1) CA2736861C (pl)
DK (1) DK2346870T3 (pl)
EA (1) EA201100598A1 (pl)
ES (1) ES2548140T3 (pl)
HK (1) HK1158190A1 (pl)
IL (1) IL212216A (pl)
PL (1) PL2346870T3 (pl)
PT (1) PT2346870E (pl)
SG (1) SG195545A1 (pl)
WO (1) WO2010040854A1 (pl)
ZA (1) ZA201101643B (pl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2146944T3 (pl) * 2007-04-11 2014-05-30 Merck & Cie Sposób otrzymywania folianów znakowanych fluorem-18
WO2013026842A1 (en) * 2011-08-22 2013-02-28 Merck & Cie 18f-saccharide-folates
US9629918B2 (en) * 2012-02-29 2017-04-25 Purdue Research Foundation Folate receptor alpha binding ligands
AU2013258027B2 (en) 2012-05-08 2017-11-30 Merck & Cie 18F-labelled follate/antifolate analogues
CN103267330A (zh) * 2013-05-13 2013-08-28 张汉兵 一种具有消毒作用的快速加湿器
CN103333079B (zh) * 2013-07-03 2016-08-17 广东回旋医药科技股份有限公司 亚氨基酸类pet显像剂及其制备方法与应用
US11162937B2 (en) 2013-11-19 2021-11-02 Purdue Research Foundation Patient selection method for inflammation
CN105963724B (zh) * 2016-05-11 2019-01-15 厦门大学 一种放射性标记的肿瘤显像剂、其制备方法和应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4202976A (en) 1973-09-11 1980-05-13 Bayly Russell J Selenium-75 labelled derivatives of folates
GB1501119A (en) 1974-12-20 1978-02-15 Radiochemical Centre Ltd Folate compounds
US4276280A (en) 1976-09-29 1981-06-30 Becton, Dickinson And Company Radiolabeled derivatives of folic acid
US4298735A (en) 1979-04-30 1981-11-03 Union Carbide Corporation Folic acid derivatives
US4314988A (en) 1979-10-31 1982-02-09 Baker Instruments Corp. Folic acid derivatives and process for preparation
JPS6144890A (ja) * 1984-08-08 1986-03-04 Shionogi & Co Ltd 含フツ素メトトレキサ−ト誘導体
US4584375A (en) * 1984-08-21 1986-04-22 Rensselaer Polytechnic Institute Fluorine-containing antifolates incapable of polyglutamate formation
US4628090A (en) 1984-08-21 1986-12-09 Rensselaer Polytechnic Institute Fluorine-containing antifolates incapable of polyglutanayte formation related compounds
US5066828A (en) 1990-04-12 1991-11-19 Merrell Dow Pharmaceuticals Inc. Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
US5286726A (en) 1990-04-12 1994-02-15 The Regents Of The University Of Michigan Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
DE4040651A1 (de) * 1990-12-19 1992-06-25 Boehringer Mannheim Gmbh Pteridin-derivate, verfahren zu ihrer herstellung sowie deren verwendung zur herstellung von immunogenen
CA2494704A1 (en) 2002-08-02 2004-12-23 Mallinckrodt Inc. Radioactively labelled amino acid analogues, their preparation and use
GB0428012D0 (en) * 2004-12-22 2005-01-26 Hammersmith Imanet Ltd Radiolabelling methods
ES2731448T3 (es) 2004-12-23 2019-11-15 Purdue Research Foundation Procedimiento de análisis por imagen mediante tomografía por emisión de positrones
EP2086924B1 (de) 2006-11-01 2018-09-12 Piramal Imaging SA [f-18]markierte l-glutaminsäure, [f-18]markiertes l-glutamin, ihre derivate und ihre verwendung sowie verfahren zu ihrer herstellung
JP5869205B2 (ja) 2007-02-07 2016-02-24 パーデュー・リサーチ・ファウンデーションPurdue Research Foundation ポジトロン放射断層画像法
PL2146944T3 (pl) 2007-04-11 2014-05-30 Merck & Cie Sposób otrzymywania folianów znakowanych fluorem-18
WO2008125617A2 (en) 2007-04-11 2008-10-23 Merck Eprova Ag 18f-labelled folates
DK2144912T3 (da) 2007-04-11 2013-01-14 Merck & Cie 18 f-mærkede folater

Also Published As

Publication number Publication date
AU2009301042A1 (en) 2010-04-15
WO2010040854A1 (en) 2010-04-15
ES2548140T3 (es) 2015-10-14
HK1158190A1 (en) 2012-07-13
JP2012505186A (ja) 2012-03-01
IL212216A (en) 2016-02-29
JP5730771B2 (ja) 2015-06-10
CN102177160A (zh) 2011-09-07
CA2736861A1 (en) 2010-04-15
US10961246B2 (en) 2021-03-30
AU2009301042B2 (en) 2015-07-23
CA2736861C (en) 2017-11-14
IL212216A0 (en) 2011-06-30
PT2346870E (pt) 2015-10-21
SG195545A1 (en) 2013-12-30
US20110286921A1 (en) 2011-11-24
KR101756793B1 (ko) 2017-07-11
ZA201101643B (en) 2011-11-30
EP2346870A1 (en) 2011-07-27
EP2346870B1 (en) 2015-08-05
DK2346870T3 (en) 2015-08-17
CN102177160B (zh) 2014-11-26
KR20110079895A (ko) 2011-07-11
US20180072734A1 (en) 2018-03-15
EA201100598A1 (ru) 2011-12-30

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