[go: up one dir, main page]

PL2222839T3 - Sposoby i kompozycje do modulowania i różnicowania pluripotencjalnych komórek - Google Patents

Sposoby i kompozycje do modulowania i różnicowania pluripotencjalnych komórek

Info

Publication number
PL2222839T3
PL2222839T3 PL08856546T PL08856546T PL2222839T3 PL 2222839 T3 PL2222839 T3 PL 2222839T3 PL 08856546 T PL08856546 T PL 08856546T PL 08856546 T PL08856546 T PL 08856546T PL 2222839 T3 PL2222839 T3 PL 2222839T3
Authority
PL
Poland
Prior art keywords
compositions
methods
pluripotential cells
modulating differentiation
differentiation
Prior art date
Application number
PL08856546T
Other languages
English (en)
Inventor
Irina Aizman
Original Assignee
Sanbio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanbio Inc filed Critical Sanbio Inc
Publication of PL2222839T3 publication Critical patent/PL2222839T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/42—Notch; Delta; Jagged; Serrate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PL08856546T 2007-12-03 2008-12-03 Sposoby i kompozycje do modulowania i różnicowania pluripotencjalnych komórek PL2222839T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US521107P 2007-12-03 2007-12-03
US12594108P 2008-04-30 2008-04-30
US13157708P 2008-06-10 2008-06-10
EP08856546.0A EP2222839B1 (en) 2007-12-03 2008-12-03 Methods and compositions for modulating differentiation of pluripotential cells
PCT/US2008/013299 WO2009073180A2 (en) 2007-12-03 2008-12-03 Methods and compositions for modulating differentiation of pluripotential cells

Publications (1)

Publication Number Publication Date
PL2222839T3 true PL2222839T3 (pl) 2016-02-29

Family

ID=40718417

Family Applications (1)

Application Number Title Priority Date Filing Date
PL08856546T PL2222839T3 (pl) 2007-12-03 2008-12-03 Sposoby i kompozycje do modulowania i różnicowania pluripotencjalnych komórek

Country Status (7)

Country Link
US (1) US20110306137A1 (pl)
EP (3) EP2222839B1 (pl)
DK (1) DK2222839T3 (pl)
ES (2) ES2787513T3 (pl)
PL (1) PL2222839T3 (pl)
PT (1) PT2222839E (pl)
WO (1) WO2009073180A2 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1479767T3 (da) 2002-02-06 2013-11-25 Sanbio Inc Fremgangsmåde til differentiering/inducering af stromaceller fra knoglemarv til nerveceller ved overføring af Notch-gen
EP3118308B1 (en) * 2008-04-30 2021-03-03 SanBio, Inc. Neural regenerating cells with alterations in dna methylation
CA2862309A1 (en) 2012-01-27 2013-08-01 Sanbio, Inc. Methods and compositions for modulating angiogenesis and vasculogenesis
US9828593B2 (en) 2012-05-16 2017-11-28 Sanbio, Inc. Methods and compositions for treatment of traumatic brain injury and for modulation of migration of neurogenic cells
CN104797264A (zh) 2012-10-09 2015-07-22 桑比欧公司 用于治疗视网膜变性的方法和组合物
WO2016210256A1 (en) * 2015-06-25 2016-12-29 The University Of Florida Research Foundation, Inc. Conductive nonwoven mat and method of using the conductive nonwoven mat

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2246085T3 (es) 1998-05-07 2006-02-01 University Of South Florida Celulas de medula osea como fuente de neuronas util para reparar la medula espinal y el cerebro.
US6534261B1 (en) 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US7015037B1 (en) * 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
WO2001059072A1 (en) 2000-02-11 2001-08-16 Philadelphia Health And Education Corporation Differentiation of bone marrow cells into neuronal cells and uses therefor
US20030003090A1 (en) 2001-05-31 2003-01-02 Prockop Darwin J. Directed in vitro differentiation of marrow stromal cells into neural cell progenitors
JP3886346B2 (ja) 2001-06-22 2007-02-28 サンバイオ，インコーポレイティド 骨髄間質細胞由来Ｓｃｈｗａｎｎ細胞を含む神経再生用医薬組成物
US7129034B2 (en) 2001-10-25 2006-10-31 Cedars-Sinai Medical Center Differentiation of whole bone marrow
DK1479767T3 (da) * 2002-02-06 2013-11-25 Sanbio Inc Fremgangsmåde til differentiering/inducering af stromaceller fra knoglemarv til nerveceller ved overføring af Notch-gen
US20030181380A1 (en) * 2002-03-08 2003-09-25 Pear Warren S. Modulating lymphoid commitment and survival
US20040235165A1 (en) 2003-05-19 2004-11-25 Darwin Prockop In vitro differentiation of adult stem cells
KR20130062359A (ko) 2004-04-12 2013-06-12 산바이오 인코포레이티드 뉴런의 전구 세포 특징들을 나타내는 세포

Also Published As

Publication number Publication date
ES2551356T3 (es) 2015-11-18
EP2222839A2 (en) 2010-09-01
EP2985341B1 (en) 2020-04-01
EP2985341A2 (en) 2016-02-17
WO2009073180A2 (en) 2009-06-11
WO2009073180A3 (en) 2009-10-15
EP2222839A4 (en) 2012-02-01
ES2787513T3 (es) 2020-10-16
EP3696261A1 (en) 2020-08-19
US20110306137A1 (en) 2011-12-15
DK2222839T3 (en) 2015-12-21
EP2985341A3 (en) 2016-06-01
EP2222839B1 (en) 2015-09-16
PT2222839E (pt) 2015-11-30

Similar Documents

Publication Publication Date Title
IL252119A0 (en) Improved composition of cells and methods for its preparation
GB0622394D0 (en) Differentiation of pluripotent cells
HK1216905A1 (zh) 多能幹細胞的分化
HK1196034A1 (zh) 細胞及組織的冷凍保存用組合物
TWI368618B (en) Compounds and compositions as modulators of gpr119 activity
ZA201008392B (en) Treatment of pluripotent cells
HK1142926A1 (en) Differentiation of human embryonic stem cells
IL202329A0 (en) Methods and compositions for stimulating cells
IL224959A (en) Methods and preparations for producing bax-free cell lines
PL2262471T3 (pl) Kompozycja i zastosowania do wpływania na wzrost włosów
WO2010123759A9 (en) Compositions and methods for treating burns
EP2129680A4 (en) COMBINED HAIR-ANTISENSE HAIR LOOP COMPOSITIONS AND METHODS FOR MODULATING EXPRESSION
EP2249789A4 (en) COMPOSITIONS AND METHODS FOR THE TREATMENT OF XEROSOMY
EP2192907A4 (en) ERYTHROPOETIN AND FIBRONECTINE COMPOSITIONS FOR THERAPEUTIC AND COSMETIC APPLICATIONS
ZA200907240B (en) Cell lines, compositions comprising them for the treatment of melanomas, procedures to prepare the compositions, and treatment methods
EP2015782A4 (en) COMPOSITIONS AND METHODS FOR MODULATING GENE EXPRESSION
PT2222839E (pt) Métodos e composições para modular a diferenciação de células pluripotentes
HK1141682A1 (en) New compositions and methods for cell killing
EP2300044A4 (en) METHOD AND COMPOSITIONS FOR TREATING PAIN WITH OMEGA CONOTOXINES
GB0904743D0 (en) Methods and compositions for modulating cardiac contractility
EP2142195A4 (en) COMPOSITION FOR PROMOTING THE MAINTENANCE AND FUNCTIONING OF MUSCLE-SPECIFIC PROVISIONAL CELLS
GB0808326D0 (en) Compositions and methods for the treatment of fybromyalgia
ZA201003689B (en) Compositions and methods for the treatment of xerostomia
AU2007903225A0 (en) Differentiation of human embryonic stem cells
IL203964A (en) Drugs of erythropoietin and fibronectin for medicinal and cosmetic uses