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PL2061897T3 - Proces fermentacji okresowej z zasilaniem o wysokiej gęstości komórek do produkcji rekombinowanego białka - Google Patents

Proces fermentacji okresowej z zasilaniem o wysokiej gęstości komórek do produkcji rekombinowanego białka

Info

Publication number
PL2061897T3
PL2061897T3 PL07836299T PL07836299T PL2061897T3 PL 2061897 T3 PL2061897 T3 PL 2061897T3 PL 07836299 T PL07836299 T PL 07836299T PL 07836299 T PL07836299 T PL 07836299T PL 2061897 T3 PL2061897 T3 PL 2061897T3
Authority
PL
Poland
Prior art keywords
recombinant protein
cell density
fermentation process
batch fermentation
producing recombinant
Prior art date
Application number
PL07836299T
Other languages
English (en)
Inventor
Wei-Qiang Willie Sun
Earl Pursell
Original Assignee
Wyeth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Llc filed Critical Wyeth Llc
Publication of PL2061897T3 publication Critical patent/PL2061897T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL07836299T 2006-07-27 2007-07-21 Proces fermentacji okresowej z zasilaniem o wysokiej gęstości komórek do produkcji rekombinowanego białka PL2061897T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83347906P 2006-07-27 2006-07-27
EP07836299.3A EP2061897B1 (en) 2006-07-27 2007-07-21 High-cell density fed-batch fermentation process for producing recombinant protein
PCT/US2007/016917 WO2008013943A2 (en) 2006-07-27 2007-07-21 High-cell density fed-batch fermentation process for producing recombinant protein

Publications (1)

Publication Number Publication Date
PL2061897T3 true PL2061897T3 (pl) 2020-09-07

Family

ID=38982103

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07836299T PL2061897T3 (pl) 2006-07-27 2007-07-21 Proces fermentacji okresowej z zasilaniem o wysokiej gęstości komórek do produkcji rekombinowanego białka

Country Status (20)

Country Link
US (3) US8632995B2 (pl)
EP (2) EP2061897B1 (pl)
JP (2) JP2009544321A (pl)
KR (1) KR101419958B1 (pl)
CN (2) CN101535493A (pl)
AU (1) AU2007277081B2 (pl)
BR (1) BRPI0715360B8 (pl)
CA (1) CA2657135C (pl)
DK (1) DK2061897T3 (pl)
ES (1) ES2788001T3 (pl)
HK (1) HK1217969A1 (pl)
HU (1) HUE048973T2 (pl)
IL (1) IL196496A (pl)
MX (1) MX2009000813A (pl)
PL (1) PL2061897T3 (pl)
PT (1) PT2061897T (pl)
RU (1) RU2451070C2 (pl)
SG (1) SG174013A1 (pl)
SI (1) SI2061897T1 (pl)
WO (1) WO2008013943A2 (pl)

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MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
CA2657135C (en) 2006-07-27 2016-03-15 Wyeth High-cell density fed-batch fermentation process for producing recombinant protein
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
PL3831406T3 (pl) 2010-08-23 2024-09-09 Wyeth Llc Stabilne preparaty antygenów rLP2086 Neisseria meningitidis
JP5976652B2 (ja) 2010-09-10 2016-08-24 ワイス・エルエルシー 髄膜炎菌ｏｒｆ２０８６抗原の非脂質化変異体
EP2670839B1 (en) * 2011-01-31 2017-11-08 Novozymes A/S Use of browned glucose for the fermentative production of thaxtomin.
KR101763625B1 (ko) 2012-03-09 2017-08-01 화이자 인코포레이티드 수막염균 조성물 및 이의 사용 방법
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
EP2825633B1 (en) * 2012-03-12 2019-03-06 Hanmi Science Co., Ltd. Method of culturing e. coli cells for high density
EP2964665B1 (en) 2013-03-08 2018-08-01 Pfizer Inc Immunogenic fusion polypeptides
KR101905278B1 (ko) 2013-09-08 2018-10-08 화이자 인코포레이티드 나이세리아 메닌지티디스 조성물 및 그의 방법
RU2561467C1 (ru) * 2014-04-24 2015-08-27 Сергей Михайлович Юдин Способ получения препарата для повышения мясной и молочной продуктивности сельскохозяйственных животных (варианты) и препарат, полученный на его основе
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US10322304B2 (en) * 2015-01-29 2019-06-18 Sandy Kronenberg Nasal air filter
KR20190049940A (ko) 2015-02-19 2019-05-09 화이자 인코포레이티드 나이세리아 메닌지티디스 조성물 및 그의 방법
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
EP4467565A3 (en) 2016-12-21 2025-03-12 Amgen Inc. Anti-tnf alpha antibody formulations
AU2018215585B2 (en) 2017-01-31 2022-03-17 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
US11991994B2 (en) 2019-10-30 2024-05-28 Future Fields Cellular Agriculture and Research LTD. Method for producing recombinant proteins in insects
CN117510596A (zh) * 2023-11-13 2024-02-06 中山迈托姆生物技术有限公司 一种大肠杆菌高密度表达犬瘟热抗原的发酵工艺及其应用

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US4414329A (en) * 1980-01-15 1983-11-08 Phillips Petroleum Company Biochemical conversions by yeast fermentation at high cell densities
GB8516415D0 (en) * 1985-06-28 1985-07-31 Celltech Ltd Culture of animal cells
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US5681718A (en) 1986-03-14 1997-10-28 Celltech Limited Methods for enhanced production of tissue plasminogen activator in cell culture using alkanoic acids or salts thereof
RU2111246C1 (ru) * 1992-06-03 1998-05-20 Дербышев Виктор Викторович Способ получения биомассы аэробнорастущих микроорганизмов
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AR005035A1 (es) * 1995-12-11 1999-04-07 Merck Patent Ges Mit Beschränkter Haftung Procedimiento para preparar proteinas recombinantes en e. coli, mediante fermentacion con gran concentracion de celulas.
JP2001500015A (ja) 1996-09-06 2001-01-09 トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア Ｔ７ポリメラーゼを利用する組換えアデノ随伴ウイルスの誘導可能な製造方法
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CA2657135C (en) * 2006-07-27 2016-03-15 Wyeth High-cell density fed-batch fermentation process for producing recombinant protein

Also Published As

Publication number Publication date
CA2657135A1 (en) 2008-01-31
US20080026425A1 (en) 2008-01-31
JP2009544321A (ja) 2009-12-17
BRPI0715360B1 (pt) 2021-01-19
RU2451070C2 (ru) 2012-05-20
WO2008013943A2 (en) 2008-01-31
IL196496A0 (en) 2011-08-01
ES2788001T3 (es) 2020-10-20
JP5925175B2 (ja) 2016-05-25
CA2657135C (en) 2016-03-15
EP2061897B1 (en) 2020-03-25
KR20090034375A (ko) 2009-04-07
JP2014064583A (ja) 2014-04-17
PT2061897T (pt) 2020-05-08
DK2061897T3 (da) 2020-06-02
US8632995B2 (en) 2014-01-21
EP2061897A2 (en) 2009-05-27
SI2061897T1 (sl) 2020-07-31
EP3705579A1 (en) 2020-09-09
HK1217969A1 (zh) 2017-01-27
RU2008152445A (ru) 2010-09-10
HUE048973T2 (hu) 2020-09-28
EP2061897A4 (en) 2012-03-07
US20160289725A1 (en) 2016-10-06
IL196496A (en) 2016-05-31
BRPI0715360B8 (pt) 2022-01-04
US9279000B2 (en) 2016-03-08
AU2007277081B2 (en) 2014-02-06
CN101535493A (zh) 2009-09-16
MX2009000813A (es) 2009-02-03
CN105463045A (zh) 2016-04-06
KR101419958B1 (ko) 2014-07-16
SG174013A1 (en) 2011-09-29
WO2008013943A3 (en) 2009-04-02
BRPI0715360A2 (pt) 2013-06-18
AU2007277081A1 (en) 2008-01-31
US10301663B2 (en) 2019-05-28
US20140113329A1 (en) 2014-04-24

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