PH18748A - Myocardium-protecting pyridine derivatives having an anti-arrythmic activity and an activity as blood-platelets antiaggregents - Google Patents

Myocardium-protecting pyridine derivatives having an anti-arrythmic activity and an activity as blood-platelets antiaggregents

Info

Publication number: PH18748A
Authority: PH; Philippines
Prior art keywords: activity; antiaggregents; myocardium; platelets; protecting
Prior art date: 1979-10-11

Application number

PH24692A

Other languages

English (en)

Inventor

Henri Demarne

Jacqueline Lansen

Claude Bernhart

Original Assignee

Sanofi Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-10-11

Filing date

1980-10-09

Publication date

1985-09-19

1980-10-09 Application filed by Sanofi Sa filed Critical Sanofi Sa

1985-09-19 Publication of PH18748A publication Critical patent/PH18748A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/57—Nitriles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

PH24692A 1979-10-11 1980-10-09 Myocardium-protecting pyridine derivatives having an anti-arrythmic activity and an activity as blood-platelets antiaggregents PH18748A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR7925370A FR2467200A1 (fr)	1979-10-11	1979-10-11	Derives du pyrrole actifs sur les troubles du rythme cardiovasculaire

Publications (1)

Publication Number	Publication Date
PH18748A true PH18748A (en)	1985-09-19

Family

ID=9230594

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PH24692A PH18748A (en)	1979-10-11	1980-10-09	Myocardium-protecting pyridine derivatives having an anti-arrythmic activity and an activity as blood-platelets antiaggregents

Country Status (26)

Country	Link
US (1)	US4356177A (xx)
EP (1)	EP0027412B1 (xx)
JP (1)	JPS5661355A (xx)
AR (2)	AR231129A1 (xx)
AT (1)	ATE5561T1 (xx)
AU (1)	AU540556B2 (xx)
BR (1)	BR8006547A (xx)
CA (1)	CA1156653A (xx)
CS (2)	CS225840B2 (xx)
DD (1)	DD153549A5 (xx)
DE (1)	DE3065906D1 (xx)
DK (1)	DK156650C (xx)
ES (1)	ES8200347A1 (xx)
FI (1)	FI75339C (xx)
FR (1)	FR2467200A1 (xx)
GR (1)	GR69616B (xx)
HU (1)	HU184330B (xx)
IE (1)	IE50827B1 (xx)
IL (1)	IL61250A (xx)
NO (1)	NO153849C (xx)
NZ (1)	NZ195233A (xx)
PH (1)	PH18748A (xx)
PT (1)	PT71888B (xx)
SU (2)	SU1011048A3 (xx)
YU (2)	YU42537B (xx)
ZA (1)	ZA806180B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2535722B1 (fr) *	1982-11-08	1985-06-28	Sanofi Sa	Derives de la g-butyrolactone protecteurs du myocarde presentant une activite antiarythmique, procede pour leur preparation et medicaments en contenant
FR2535721A1 (fr) *	1982-11-08	1984-05-11	Sanofi Sa	Derives de la piperidinedione protecteurs du myocarde presentant une acticite antiarythmique, leur procede de preparation et les medicaments qui contiennent lesdits derives
US4783537A (en) *	1985-11-13	1988-11-08	Pennwalt Corporation	α-(aminoalkyl)-arylacetic acid derivatives
US4847301A (en) *	1985-11-13	1989-07-11	Pennwalt Corporation	Methods of use of α-(aminoalkyl)-arylacetic acid derivatives
FR2856061A1 (fr) *	2003-06-11	2004-12-17	Chrysalon	Derives polycycliques ortho-condenses de l'aminopyrrole a substituant electroattracteur chimiotheques combinatoires desdits derives et leur procede d'obtention

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL70757C (xx) *	1947-10-13
GB915804A (en) *	1958-04-12	1963-01-16	Degussa	Process for the production of basically substituted carboxylic acid amides
FR2485M (fr) *	1961-05-17	1964-04-27	Searle & Co	Nouveaux régulateurs cardiaques.
CA1073892A (en) *	1976-08-03	1980-03-18	John M. Holmes	Mixed metal amide catalysts for h-d exchange in amines

1979
- 1979-10-11 FR FR7925370A patent/FR2467200A1/fr active Granted
1980
- 1980-10-07 ZA ZA00806180A patent/ZA806180B/xx unknown
- 1980-10-07 US US06/194,829 patent/US4356177A/en not_active Expired - Lifetime
- 1980-10-08 AT AT80401433T patent/ATE5561T1/de not_active IP Right Cessation
- 1980-10-08 DE DE8080401433T patent/DE3065906D1/de not_active Expired
- 1980-10-08 ES ES495745A patent/ES8200347A1/es not_active Expired
- 1980-10-08 EP EP80401433A patent/EP0027412B1/fr not_active Expired
- 1980-10-08 PT PT71888A patent/PT71888B/pt unknown
- 1980-10-09 HU HU802460A patent/HU184330B/hu not_active IP Right Cessation
- 1980-10-09 PH PH24692A patent/PH18748A/en unknown
- 1980-10-09 JP JP14184280A patent/JPS5661355A/ja active Granted
- 1980-10-10 YU YU2611/80A patent/YU42537B/xx unknown
- 1980-10-10 CS CS814303A patent/CS225840B2/cs unknown
- 1980-10-10 NZ NZ195233A patent/NZ195233A/xx unknown
- 1980-10-10 BR BR8006547A patent/BR8006547A/pt unknown
- 1980-10-10 IL IL61250A patent/IL61250A/xx unknown
- 1980-10-10 GR GR63114A patent/GR69616B/el unknown
- 1980-10-10 DD DD80224466A patent/DD153549A5/de unknown
- 1980-10-10 FI FI803221A patent/FI75339C/fi not_active IP Right Cessation
- 1980-10-10 NO NO803051A patent/NO153849C/no unknown
- 1980-10-10 AR AR282847A patent/AR231129A1/es active
- 1980-10-10 SU SU802996293A patent/SU1011048A3/ru active
- 1980-10-10 DK DK428280A patent/DK156650C/da not_active IP Right Cessation
- 1980-10-10 CS CS806875A patent/CS225823B2/cs unknown
- 1980-10-10 IE IE2112/80A patent/IE50827B1/en not_active IP Right Cessation
- 1980-10-10 CA CA000362149A patent/CA1156653A/en not_active Expired
- 1980-10-15 AU AU63283/80A patent/AU540556B2/en not_active Ceased
1981
- 1981-09-07 SU SU813328597A patent/SU1127529A3/ru active
- 1981-12-21 AR AR287891A patent/AR231975A1/es active
1983
- 1983-01-31 YU YU00212/83A patent/YU21283A/xx unknown

Also Published As

Publication number	Publication date
JPH0115501B2 (xx)	1989-03-17
YU42537B (en)	1988-10-31
CA1156653A (en)	1983-11-08
CS225840B2 (en)	1984-02-13
YU261180A (en)	1983-09-30
SU1011048A3 (ru)	1983-04-07
FR2467200B1 (xx)	1982-07-02
HU184330B (en)	1984-08-28
YU21283A (en)	1983-09-30
FI75339B (fi)	1988-02-29
AU6328380A (en)	1981-04-30
DK156650C (da)	1990-02-12
AU540556B2 (en)	1984-11-22
DK428280A (da)	1981-04-12
AR231975A1 (es)	1985-04-30
IL61250A (en)	1983-11-30
CS225823B2 (en)	1984-02-13
FR2467200A1 (fr)	1981-04-17
PT71888B (fr)	1981-08-14
EP0027412B1 (fr)	1983-12-14
BR8006547A (pt)	1981-04-14
PT71888A (fr)	1980-11-01
NZ195233A (en)	1983-05-10
NO803051L (no)	1981-04-13
ES495745A0 (es)	1981-11-16
FI803221L (fi)	1981-04-12
IE802112L (en)	1981-04-11
JPS5661355A (en)	1981-05-26
ES8200347A1 (es)	1981-11-16
ATE5561T1 (de)	1983-12-15
IL61250A0 (en)	1980-12-31
EP0027412A1 (fr)	1981-04-22
DE3065906D1 (en)	1984-01-19
FI75339C (fi)	1988-06-09
NO153849B (no)	1986-02-24
NO153849C (no)	1986-06-04
GR69616B (xx)	1982-07-05
DD153549A5 (de)	1982-01-13
AR231129A1 (es)	1984-09-28
DK156650B (da)	1989-09-18
ZA806180B (en)	1981-11-25
SU1127529A3 (ru)	1984-11-30
IE50827B1 (en)	1986-07-23
US4356177A (en)	1982-10-26

Publication	Publication Date	Title
DE3065190D1 (en)	1983-11-10	Enzyme derivatives, and their preparation
JPS5764653A (en)	1982-04-19	Agmatilene derivative and manufacture
EP0003383A3 (en)	1979-09-05	4-amino-3-sulfonamido pyridine derivatives and their use
AU531458B2 (en)	1983-08-25	Derivatives of oxalane substituted with pyridyl pyrrolyl and azacyclopentadiene group with herbicidal activity
GB2051062B (en)	1983-10-12	3-vinyl-cephalosporin derivatives and their preparation
NZ193904A (en)	1981-11-19	Phenoxypyridine derivatives and herbicidal compositions
AU535880B2 (en)	1984-04-12	5h-furanone-2 and 3h-dihydrofuranone-2 derivatives
IL59538A0 (en)	1980-06-30	3-substituted pyridine derivatives,their preparation and their use as funigicides
GB2001630B (en)	1982-03-17	Inosadiamine derivatives and their preparation
IL61261A0 (en)	1980-12-31	Pyridine and pyrimidine derivatives
JPS55162784A (en)	1980-12-18	Hydroxyaminooeburnane derivatives and their manufacture
PH18748A (en)	1985-09-19	Myocardium-protecting pyridine derivatives having an anti-arrythmic activity and an activity as blood-platelets antiaggregents
IL54473A0 (en)	1978-07-31	4-alkylthio-2-trifluoromethylalkane-sulfonanilides and derivatives thereof
IL54252A0 (en)	1978-06-15	Novel -aryl-acetamide derivatives and their preparation
GB2055370B (en)	1983-05-05	Ergol-8-ene and ergoline derivatives
IL54013A0 (en)	1978-04-30	Everninomicin derivatives and their preparation
GB2000776B (en)	1982-02-10	Tunicamine derivatives and their preparation
CY1334A (en)	1986-10-24	17-cycloalkylmethyl-6-methylene-morphinane derivatives and their preparation
IL60541A0 (en)	1980-09-16	Tallysomicin derivatives and their preparation
ZA80273B (en)	1981-03-25	4-phenylthioalkanesulfonanilides and derivatives thereof
JPS579777A (en)	1982-01-19	1-epi-2-deoxyfortimicin b and derivative
IL53859A (en)	1982-09-30	Dioxatricyclodecane derivatives and their preparation
JPS5610189A (en)	1981-02-02	Novel pyridine derivatives and drug containing them
GB2117375B (en)	1984-05-02	N-alkysulfonyl-and n-alkoxycarbonyl-substituted alkanesulfonanilides and derivatives thereof
PH16300A (en)	1983-09-05	Notrothiazoline derivatives and their use as schistosonicidal agents