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PH12022550133A1 - Immunogenic composition comprising multivalent streptococcus pneumoniae polysaccharide-protein conjugates and pharmaceutical use thereof - Google Patents

Immunogenic composition comprising multivalent streptococcus pneumoniae polysaccharide-protein conjugates and pharmaceutical use thereof

Info

Publication number
PH12022550133A1
PH12022550133A1 PH1/2022/550133A PH12022550133A PH12022550133A1 PH 12022550133 A1 PH12022550133 A1 PH 12022550133A1 PH 12022550133 A PH12022550133 A PH 12022550133A PH 12022550133 A1 PH12022550133 A1 PH 12022550133A1
Authority
PH
Philippines
Prior art keywords
streptococcus pneumoniae
immunogenic composition
protein conjugates
multivalent
pharmaceutical use
Prior art date
Application number
PH1/2022/550133A
Inventor
Ji Hyoun Cha
Jun Won Chwa
Kyung Min Jo
Pan Kyeom Kim
Wan Geun La
Soo Young Lee
Original Assignee
Celltrion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltrion Inc filed Critical Celltrion Inc
Publication of PH12022550133A1 publication Critical patent/PH12022550133A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to an immunogenic composition comprising multivalent Streptococcus pneumoniae polysaccharide-protein conjugates. The respective conjugates comprise capsular polysaccharides of different Streptococcus pneumoniae serotypes conjugated to carrier proteins, and thus can induce immune responses to a wider variety of serotypes compared with existing Prevenar 13. The multivalent immunogenic composition according to the present invention can be advantageously used in preventing diseases caused by Streptococcus pneumoniae in infants, children, and adults.
PH1/2022/550133A 2019-07-18 2020-07-17 Immunogenic composition comprising multivalent streptococcus pneumoniae polysaccharide-protein conjugates and pharmaceutical use thereof PH12022550133A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20190087004 2019-07-18
PCT/KR2020/009474 WO2021010798A1 (en) 2019-07-18 2020-07-17 Immunogenic composition comprising multivalent streptococcus pneumoniae polysaccharide-protein conjugates

Publications (1)

Publication Number Publication Date
PH12022550133A1 true PH12022550133A1 (en) 2022-11-14

Family

ID=74211166

Family Applications (1)

Application Number Title Priority Date Filing Date
PH1/2022/550133A PH12022550133A1 (en) 2019-07-18 2020-07-17 Immunogenic composition comprising multivalent streptococcus pneumoniae polysaccharide-protein conjugates and pharmaceutical use thereof

Country Status (8)

Country Link
JP (1) JP7441301B2 (en)
KR (1) KR20210010412A (en)
CN (1) CN114364397B (en)
AU (1) AU2020315673B2 (en)
MY (1) MY207971A (en)
PH (1) PH12022550133A1 (en)
TW (1) TWI864052B (en)
WO (1) WO2021010798A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019050814A1 (en) * 2017-09-07 2019-03-14 Merck Sharp & Dohme Corp. Pneumococcal polysaccharides and their use in immunogenic polysaccharide-carrier protein conjugates
US11116828B2 (en) 2017-12-06 2021-09-14 Merck Sharp & Dohme Corp. Compositions comprising Streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
GEP20247633B (en) 2018-12-19 2024-06-25 Merck Sharp & Dohme Llc Compositions comprising streptococcus pneumoniae polysaccharide-protein conjugates and methods of use thereof
KR20220102871A (en) * 2021-01-14 2022-07-21 (주)셀트리온 The immunogenic composition comprising multivalent pneumococcal polysaccharide-protein conjugate
GB2614916A (en) * 2022-01-25 2023-07-26 Optivalent Ltd Intradermal vaccine complement
CN116942804A (en) * 2022-04-19 2023-10-27 上海瑞宙生物科技有限公司 Component of multivalent pneumococcal polysaccharide conjugate vaccine and application thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1973564T (en) * 2005-12-22 2017-01-24 Glaxosmithkline Biologicals Sa Vaccine comprising streptococcus pneumoniae capsular polysaccharide conjugates
TW201136603A (en) * 2010-02-09 2011-11-01 Merck Sharp & Amp Dohme Corp 15-valent pneumococcal polysaccharide-protein conjugate vaccine composition
HRP20211288T1 (en) 2014-01-21 2021-11-26 Pfizer Inc. Streptococcus pneumoniae capsular polysaccharides and conjugates thereof
CN104069504B (en) * 2014-05-11 2019-09-24 江苏康泰生物医学技术有限公司 A method of enhancing polysaccharide protein conjugate immunogenicity
AU2017336806B2 (en) * 2016-09-30 2024-06-27 Biological E Limited Multivalent pneumococcal vaccine compositions comprising polysaccharide-protein conjugates
ES3024474T3 (en) * 2016-12-30 2025-06-04 Vaxcyte Inc Polypeptide-antigen conjugates with non-natural amino acids
KR102101879B1 (en) * 2017-03-15 2020-05-29 주식회사 엘지화학 Multivalent vaccine composition against streptococcus
CN108079286B (en) 2018-01-19 2020-07-31 云南沃森生物技术股份有限公司 13-valent pneumococcal polysaccharide-protein conjugate composition and preparation method and application thereof

Also Published As

Publication number Publication date
TWI864052B (en) 2024-12-01
MY207971A (en) 2025-03-31
TW202116352A (en) 2021-05-01
JP7441301B2 (en) 2024-02-29
AU2020315673A1 (en) 2022-02-10
WO2021010798A1 (en) 2021-01-21
KR20210010412A (en) 2021-01-27
JP2022540718A (en) 2022-09-16
CN114364397B (en) 2024-03-29
CN114364397A (en) 2022-04-15
AU2020315673B2 (en) 2025-01-23

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