PE20040713A1 - Avermectina b1 y derivados de monosacaridos de avermectina b1 que tienen un sustituyente alcoximetilo en la posicion 4" o 4' - Google Patents
Avermectina b1 y derivados de monosacaridos de avermectina b1 que tienen un sustituyente alcoximetilo en la posicion 4" o 4'Info
- Publication number
- PE20040713A1 PE20040713A1 PE2003001284A PE2003001284A PE20040713A1 PE 20040713 A1 PE20040713 A1 PE 20040713A1 PE 2003001284 A PE2003001284 A PE 2003001284A PE 2003001284 A PE2003001284 A PE 2003001284A PE 20040713 A1 PE20040713 A1 PE 20040713A1
- Authority
- PE
- Peru
- Prior art keywords
- avermectin
- alkyl
- cycloalkyl
- alcoximethyl
- monosaccharid
- Prior art date
Links
- IBSREHMXUMOFBB-JFUDTMANSA-N 5u8924t11h Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O3)C=C[C@H](C)[C@@H](C(C)C)O4)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 IBSREHMXUMOFBB-JFUDTMANSA-N 0.000 title 2
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- SYSQUGFVNFXIIT-UHFFFAOYSA-N n-[4-(1,3-benzoxazol-2-yl)phenyl]-4-nitrobenzenesulfonamide Chemical compound C1=CC([N+](=O)[O-])=CC=C1S(=O)(=O)NC1=CC=C(C=2OC3=CC=CC=C3N=2)C=C1 SYSQUGFVNFXIIT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/22—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
DE FORMULA (I) DONDE: n ES 0 o 1; A-B ES -CH=CH- o -CH2-CH2-; R1 ES ALQUILO C1-C12, CICLOALQUILO C3-C8 o ALQUENILO C2-C12; R2 ES, ENTRE OTROS, ALQUILO C1-C12, ALQUENILO C2-C12 O ALQUINILO C2-C12, SUSTITUIDOS O NO CON UNO A CINCO SUSTITUYENTES SELECCIONADOS DEL GRUPO FORMADO POR OH, HALOGENO, CN, -N3, -NO2, CICLOALQUILO C3-C8, NORBORNILENIL-, CICLOALQUENILO C3-C8, HALOCICLOALQUILO C3-C8, ALCOXI C1-C12, CICLOALCOXI C3-C8, HALOALCOXI C1-C12, ALQUILTIO C1-C12, CICLOALQUILTIO C3-C8, HALOALQUILTIO C1-C12, ALQUILSULFINILO C1-C12, CICLOALQUILSULFINILO C3-C8, HALOALQUILSULFINILO C1-C12, HALOCICLOALQUILSULFINILO C3-C8, ALQUILSULFONILO C1-C12, CICLOALQUILSULFONILO C3-C8, HALOALQUILSULFONILO C1-C12, HALOCICLOALQUILSULFONILO C3-C8; R3 ES ENTRE OTROS, H, ALQUILO C1-C12 o ALQUILO C1-C12 SUSTITUIDO O NO Y, DONDE FUERE APLICABLE, A ISOMEROS E/Z, MEZCLAS DE ISOMEROS E/Z Y/O TAUTOMEROS
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0229804.0A GB0229804D0 (en) | 2002-12-20 | 2002-12-20 | Avermection b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"- or 4'-position |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20040713A1 true PE20040713A1 (es) | 2004-12-02 |
Family
ID=9950151
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2003001284A PE20040713A1 (es) | 2002-12-20 | 2003-12-12 | Avermectina b1 y derivados de monosacaridos de avermectina b1 que tienen un sustituyente alcoximetilo en la posicion 4" o 4' |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US7737261B2 (es) |
| EP (1) | EP1581546B1 (es) |
| JP (2) | JP4851094B2 (es) |
| KR (1) | KR101109500B1 (es) |
| CN (1) | CN1738828B (es) |
| AR (1) | AR042533A1 (es) |
| AU (1) | AU2003302284B2 (es) |
| BR (1) | BR0317601A (es) |
| CA (1) | CA2507774C (es) |
| CO (1) | CO5690647A1 (es) |
| ES (1) | ES2742899T3 (es) |
| GB (1) | GB0229804D0 (es) |
| IL (1) | IL169092A (es) |
| MA (1) | MA27646A1 (es) |
| MX (1) | MXPA05006036A (es) |
| PE (1) | PE20040713A1 (es) |
| PL (1) | PL211483B1 (es) |
| RU (1) | RU2330857C2 (es) |
| TW (1) | TW200512214A (es) |
| UA (1) | UA81281C2 (es) |
| WO (1) | WO2004056844A1 (es) |
| ZA (1) | ZA200504353B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0229804D0 (en) * | 2002-12-20 | 2003-01-29 | Syngenta Participations Ag | Avermection b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"- or 4'-position |
| JP2010006703A (ja) * | 2006-11-07 | 2010-01-14 | Hokko Chem Ind Co Ltd | アベルメクチンモノ配糖体誘導体 |
| RU2472801C1 (ru) * | 2011-05-11 | 2013-01-20 | Игорь Викторович Заварзин | 5-о-производные авермектина, способ их получения и антипаразитарные средства на их основе |
| RU2453553C1 (ru) * | 2011-05-11 | 2012-06-20 | Игорь Викторович Заварзин | 5-о-сукциноилавермектин, способ его получения и антипаразитарное средство на его основе |
| CN103613625B (zh) * | 2013-12-02 | 2016-03-02 | 兰州大学 | 一种阿维菌素类化合物及其制备方法和在农药中的用途 |
| CN104402954A (zh) * | 2014-11-28 | 2015-03-11 | 大庆志飞生物化工有限公司 | 甲胺基阿维菌素单糖化合物及其制备方法和用途 |
| CN104402953B (zh) * | 2014-11-28 | 2017-07-28 | 大庆志飞生物化工有限公司 | 阿维菌素单糖化合物及其制备方法和用途 |
| JP6577184B2 (ja) | 2014-12-24 | 2019-09-18 | Ntn株式会社 | 転がり軸受 |
| CN107501368B (zh) * | 2017-09-30 | 2020-02-21 | 中国科学院成都生物研究所 | 一种多拉菌素衍生物的合成及其杀虫应用 |
| CN113150053B (zh) * | 2020-01-22 | 2024-10-01 | 华东理工大学 | 偶氮苯类阿维菌素衍生物及其制备方法和应用 |
| CN113817008B (zh) * | 2021-07-15 | 2023-05-23 | 湖州师范学院 | 新型琥珀酰基十六元大环内酯的制备方法及用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US18993A (en) * | 1857-12-29 | Cider-mill | ||
| US87519A (en) * | 1869-03-02 | Improvement in furnace-stoves and registers | ||
| US148520A (en) * | 1874-03-10 | Improvement in faucets | ||
| SE434277B (sv) * | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
| GB8811037D0 (en) * | 1988-05-10 | 1988-06-15 | Glaxo Group Ltd | Chemical compounds |
| EP0353959A2 (en) | 1988-08-02 | 1990-02-07 | Beecham Group Plc | Antihelmintic macrolide antibiotics |
| SE465605B (sv) * | 1990-02-26 | 1991-10-07 | Harry Nilsson | Skivfilter |
| JP2622197B2 (ja) * | 1990-03-01 | 1997-06-18 | 三共株式会社 | １３−エーテル置換ミルベマイシン誘導体 |
| US5169839A (en) * | 1990-05-11 | 1992-12-08 | Merck & Co., Inc. | Derivatives of 3'- and 3"-o-desmethyl avermectin compounds, compositions and methods of treating melmintic and parasitic infections |
| US5262400A (en) * | 1991-06-20 | 1993-11-16 | Merck & Co., Inc. | 4α-substituted avermectin derivatives |
| US5411737A (en) * | 1991-10-15 | 1995-05-02 | Merck & Co., Inc. | Slow release syneresing polymeric drug delivery device |
| PL174488B1 (pl) * | 1993-05-10 | 1998-08-31 | Merck & Co Inc | Preparat do zwalczania pasożytów zwierząt oraz sposób wytwarzania preparatu do zwalczania pasożytów zwierząt |
| US5602107A (en) * | 1993-05-10 | 1997-02-11 | Merck & Co., Inc. | Pour-on formulations consisting of gylcols, glycerides and avermectin compounds |
| US5436355A (en) * | 1994-02-03 | 1995-07-25 | Merck & Co., Inc. | Process for making avermectin/zein compositions |
| TW327125B (en) * | 1994-02-07 | 1998-02-21 | Merck & Co Inc | Composition and method for protecting against pine exhausted |
| JPWO2002012261A1 (ja) | 2000-08-09 | 2004-01-15 | 社団法人北里研究所 | エバーメクチン誘導体 |
| CA2418975C (en) | 2000-08-09 | 2012-01-17 | Satoshi Omura | Avermectin derivatives |
| US20050169839A1 (en) * | 2002-03-05 | 2005-08-04 | Fong Tung M. | Biomarker for efficacy of appetite suppressant drugs |
| GB0229804D0 (en) * | 2002-12-20 | 2003-01-29 | Syngenta Participations Ag | Avermection b1 and avermectin b1 monosaccharide derivatives having an alkoxymethyl substituent in the 4"- or 4'-position |
-
2002
- 2002-12-20 GB GBGB0229804.0A patent/GB0229804D0/en not_active Ceased
-
2003
- 2003-12-12 PE PE2003001284A patent/PE20040713A1/es active IP Right Grant
- 2003-12-18 TW TW092135927A patent/TW200512214A/zh unknown
- 2003-12-18 AR ARP030104712A patent/AR042533A1/es active IP Right Grant
- 2003-12-19 MX MXPA05006036A patent/MXPA05006036A/es active IP Right Grant
- 2003-12-19 CN CN2003801088575A patent/CN1738828B/zh not_active Expired - Lifetime
- 2003-12-19 WO PCT/EP2003/014613 patent/WO2004056844A1/en active Application Filing
- 2003-12-19 JP JP2004561378A patent/JP4851094B2/ja not_active Expired - Fee Related
- 2003-12-19 AU AU2003302284A patent/AU2003302284B2/en not_active Ceased
- 2003-12-19 CA CA2507774A patent/CA2507774C/en not_active Expired - Fee Related
- 2003-12-19 UA UAA200507209A patent/UA81281C2/uk unknown
- 2003-12-19 PL PL377497A patent/PL211483B1/pl unknown
- 2003-12-19 ES ES03810843T patent/ES2742899T3/es not_active Expired - Lifetime
- 2003-12-19 RU RU2005122943/04A patent/RU2330857C2/ru active
- 2003-12-19 KR KR1020057011622A patent/KR101109500B1/ko active IP Right Grant
- 2003-12-19 BR BR0317601-0A patent/BR0317601A/pt not_active Application Discontinuation
- 2003-12-19 EP EP03810843.7A patent/EP1581546B1/en not_active Expired - Lifetime
- 2003-12-19 US US10/539,274 patent/US7737261B2/en active Active
-
2005
- 2005-06-09 IL IL169092A patent/IL169092A/en active IP Right Grant
- 2005-06-17 MA MA28349A patent/MA27646A1/fr unknown
- 2005-06-17 CO CO05059203A patent/CO5690647A1/es not_active Application Discontinuation
-
2006
- 2006-01-06 ZA ZA200504353A patent/ZA200504353B/en unknown
-
2010
- 2010-04-27 US US12/768,280 patent/US8017589B2/en not_active Expired - Fee Related
- 2010-12-22 JP JP2010286151A patent/JP5302297B2/ja not_active Expired - Fee Related
-
2011
- 2011-05-27 US US13/117,292 patent/US8263566B2/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration |