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PA8660301A1 - Pirazolo piridinas sustituidas, composiciones que las contienen, procedimiento de fabricacion y utilizacion - Google Patents

Pirazolo piridinas sustituidas, composiciones que las contienen, procedimiento de fabricacion y utilizacion

Info

Publication number
PA8660301A1
PA8660301A1 PA20068660301A PA8660301A PA8660301A1 PA 8660301 A1 PA8660301 A1 PA 8660301A1 PA 20068660301 A PA20068660301 A PA 20068660301A PA 8660301 A PA8660301 A PA 8660301A PA 8660301 A1 PA8660301 A1 PA 8660301A1
Authority
PA
Panama
Prior art keywords
compositions
replaced
contain
piridinas
pirazolo
Prior art date
Application number
PA20068660301A
Other languages
English (en)
Inventor
Ronan Baptiste
Michel Tabart
Franck Halley
Eric Bacque
Catherine Souaille
Antonio Ugolini
Fabrice Viviani
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36593766&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PA8660301(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR0500555A external-priority patent/FR2880891B1/fr
Priority claimed from FR0507505A external-priority patent/FR2888579A1/fr
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of PA8660301A1 publication Critical patent/PA8660301A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PIRAZOLO PIRIDINAS SUSTITUIDAS, COMPOSICIONES QUE LAS CONTIENEN, PROCEDIMIENTO DE FABRICACION Y DE UTILIZACION. LA PRESENTE INVENCION SE REFIERE PARTICULARMENTE A LA PREPARACION DE PIRAZOLO PIRIDINAS SUSTITUIDAS, A LAS COMPOSICIONES QUE LAS CONTIENEN, AL PROCEDIMIENTO PARA SU PREPARACION, Y A SU UTILIZACION COMO MEDICAMENTO, EN PARTICULAR COMO AGENTES ANTICANCEROSOS.
PA20068660301A 2005-01-19 2006-01-19 Pirazolo piridinas sustituidas, composiciones que las contienen, procedimiento de fabricacion y utilizacion PA8660301A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0500555A FR2880891B1 (fr) 2005-01-19 2005-01-19 Pyrazolo pyridines substituees, compositions les contenant, procede de fabrication et utilisation
FR0507505A FR2888579A1 (fr) 2005-07-13 2005-07-13 Pyrazolo pyridines substituees, compositions les contenant, procede de fabrication et utilisation

Publications (1)

Publication Number Publication Date
PA8660301A1 true PA8660301A1 (es) 2006-09-08

Family

ID=36593766

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20068660301A PA8660301A1 (es) 2005-01-19 2006-01-19 Pirazolo piridinas sustituidas, composiciones que las contienen, procedimiento de fabricacion y utilizacion

Country Status (24)

Country Link
US (2) US8008322B2 (es)
EP (1) EP1845978B1 (es)
JP (1) JP2008527025A (es)
KR (1) KR20070098923A (es)
AR (1) AR052357A1 (es)
AT (1) ATE477799T1 (es)
AU (1) AU2006207442A1 (es)
BR (1) BRPI0606504A2 (es)
CA (1) CA2595041A1 (es)
CY (1) CY1110926T1 (es)
DE (1) DE602006016233D1 (es)
DK (1) DK1845978T3 (es)
HR (1) HRP20100624T8 (es)
IL (1) IL184524A0 (es)
MX (1) MX2007008790A (es)
PA (1) PA8660301A1 (es)
PE (1) PE20061119A1 (es)
PL (1) PL1845978T3 (es)
PT (1) PT1845978E (es)
RU (1) RU2375360C2 (es)
SI (1) SI1845978T1 (es)
TW (1) TW200639173A (es)
UY (1) UY29341A1 (es)
WO (1) WO2006077319A1 (es)

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FR2871158A1 (fr) 2004-06-04 2005-12-09 Aventis Pharma Sa Indazoles substitues, compositions les contenant, procede de fabrication et utilisation
FR2889526B1 (fr) 2005-08-04 2012-02-17 Aventis Pharma Sa 7-aza-indazoles substitues, compositions les contenant, procede de fabrication et utilisation
TW200815438A (en) * 2006-06-13 2008-04-01 Bayer Schering Pharma Ag Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
EP1870410A1 (en) * 2006-06-13 2007-12-26 Bayer Schering Pharma Aktiengesellschaft Substituted arylpyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
EP1932845A1 (en) * 2006-12-15 2008-06-18 Bayer Schering Pharma Aktiengesellschaft 3-H-pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
CA2672367A1 (en) * 2006-12-15 2008-06-19 Bayer Schering Pharma Aktiengesellschaft 3-h-pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
EP2042500A1 (en) * 2007-09-21 2009-04-01 Bayer Schering Pharma Aktiengesellschaft N-[4-(1-H-pyrazolo[3,4-c]pyridin-4-yl)phenyl]-N'-[(hetero)aryl]-urea compounds, pharmaceutical compositions comprising them, their preparation and their use as Tie2-kinase inhibitors
US20110160232A1 (en) 2007-10-04 2011-06-30 Pingda Ren Certain chemical entities and therapeutic uses thereof
AU2008331733A1 (en) * 2007-11-02 2009-06-11 Vertex Pharmaceuticals Incorporated [1H- pyrazolo [3, 4-b] pyridine-4-yl] -phenyle or -pyridin-2-yle derivatives as protein kinase C-theta
EP2070929A1 (en) 2007-12-11 2009-06-17 Bayer Schering Pharma Aktiengesellschaft Alkynylaryl compounds and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
US8841304B2 (en) 2008-01-08 2014-09-23 Array Biopharma, Inc. Pyrrolopyridines as kinase inhibitors
CN101965347B (zh) 2008-01-09 2013-01-02 阵列生物制药公司 作为激酶抑制剂的吡唑并吡啶
JP5547099B2 (ja) * 2008-03-14 2014-07-09 インテリカイン， エルエルシー キナーゼ阻害剤および使用方法
WO2009114874A2 (en) * 2008-03-14 2009-09-17 Intellikine, Inc. Benzothiazole kinase inhibitors and methods of use
MX2011000216A (es) 2008-07-08 2011-03-29 Intellikine Inc Inhibidores de cinasa y metodos para su uso.
US8476282B2 (en) * 2008-11-03 2013-07-02 Intellikine Llc Benzoxazole kinase inhibitors and methods of use
RU2011142182A (ru) * 2009-03-19 2013-04-27 Медикал Рисерч Каунсил Текнолоджи Соединения
WO2011019780A1 (en) 2009-08-11 2011-02-17 Bristol-Myers Squibb Company Azaindazoles as btk kinase modulators and use thereof
US8222416B2 (en) * 2009-12-14 2012-07-17 Hoffmann-La Roche Inc. Azaindole glucokinase activators
GB201008134D0 (en) * 2010-05-14 2010-06-30 Medical Res Council Technology Compounds
US8916553B2 (en) 2010-07-26 2014-12-23 Bristol-Myers Squibb Company Sulfonamide compounds useful as CYP17 inhibitors
GB201015949D0 (en) 2010-09-22 2010-11-03 Medical Res Council Technology Compounds
EP2638041B1 (en) 2010-11-12 2015-07-22 Bristol-Myers Squibb Company Substituted azaindazole compounds
JP6130305B2 (ja) 2011-02-23 2017-05-17 インテリカイン， エルエルシー キナーゼ阻害剤の組み合わせおよびそれらの使用
US20140161720A1 (en) * 2011-05-26 2014-06-12 The General Hospital Corporation Treatment of angiogenic- or vascular-associated diseases
BR112014003296A2 (pt) * 2011-08-12 2017-03-14 Hoffmann La Roche composto, composição farmacêutica, processo para a preparação de uma composição farmacêutica, método para o tratamento de uma doença ou distúrbio, conjunto para o tratamento de uma condição mediada pela quinase pim e utilização do composto
US9085578B2 (en) 2012-02-20 2015-07-21 Takeda Pharmaceutical Company Limited Heterocyclic compound
AU2013323508B2 (en) * 2012-09-28 2017-11-02 Merck Sharp & Dohme Corp. Novel compounds that are ERK inhibitors
ES2929906T3 (es) 2012-12-28 2022-12-02 Crystalgenomics Inc Derivado de 2,3-dihidro-isoindol-1-ona como supresor de cinasa BTK, y composición farmacéutica que lo incluye
TWI629275B (zh) * 2013-03-13 2018-07-11 賽諾菲公司 Ｎ－（４－（氮雜吲唑－６－基）－苯基）－磺醯胺及其作為醫藥之用途
CN103524421B (zh) * 2013-09-29 2015-04-01 镇江蓝德特药业科技有限公司 新型萘脲类衍生物及其医疗应用
US11873303B2 (en) 2018-04-05 2024-01-16 Merck Patent Gmbh Substituted pyrazoles as type II IRAK inhibitors
UY38349A (es) 2018-08-30 2020-03-31 Array Biopharma Inc Compuestos de pirazolo[3,4-b]piridina como inhibidores de cinasas tam y met
MX2024007885A (es) * 2021-12-22 2024-09-23 Anaxis Pharma Pty Ltd Compuestos de arilsulfonamida.

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JP4272338B2 (ja) * 2000-09-22 2009-06-03 バイエル アクチェンゲゼルシャフト ピリジン誘導体
FR2827603B1 (fr) 2001-07-18 2003-10-17 Oreal Composes derives de diaminopyrazole substitues par un radical heteroaromatique et leur utilisation en teinture d'oxydation des fibres keratiniques
GB0128287D0 (en) * 2001-11-26 2002-01-16 Smithkline Beecham Plc Novel method and compounds
EP1534389A2 (en) * 2002-07-23 2005-06-01 SmithKline Beecham Corporation Pyrazolopyrimidines as kinase inhibitors
BR0313396A (pt) * 2002-08-12 2005-06-28 Sugen Inc 3-pirrolil-piridopirazóis e 3-pirrolil-indazóis, como inibidores de quinase
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WO2005009389A2 (en) 2003-07-23 2005-02-03 Exelixis, Inc. Anaplastic lymphoma kinase modulators and methods of use
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US7812166B2 (en) * 2004-10-29 2010-10-12 Abbott Laboratories Kinase inhibitors
US7563781B2 (en) 2005-01-14 2009-07-21 Janssen Pharmaceutica Nv Triazolopyrimidine derivatives
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JP2008533032A (ja) 2005-03-10 2008-08-21 シージーアイ ファーマシューティカルズ，インコーポレイティド 或る種の置換アミド、その製造方法及び使用方法
FR2889526B1 (fr) 2005-08-04 2012-02-17 Aventis Pharma Sa 7-aza-indazoles substitues, compositions les contenant, procede de fabrication et utilisation
CA2627089A1 (en) 2005-11-09 2007-05-18 Memory Pharmaceuticals Corporation 1 h-indazoles, benzothiazoles, 1,2-benzoisoxazoles, 1,2-benzoisothiazoles, and chromones and preparation and uses thereof
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EP1870410A1 (en) * 2006-06-13 2007-12-26 Bayer Schering Pharma Aktiengesellschaft Substituted arylpyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
TW200815438A (en) * 2006-06-13 2008-04-01 Bayer Schering Pharma Ag Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same

Also Published As

Publication number Publication date
AR052357A1 (es) 2007-03-14
BRPI0606504A2 (pt) 2009-06-30
MX2007008790A (es) 2007-09-11
ATE477799T1 (de) 2010-09-15
DE602006016233D1 (de) 2010-09-30
RU2007131274A (ru) 2009-02-27
US20080039491A1 (en) 2008-02-14
EP1845978B1 (fr) 2010-08-18
WO2006077319A1 (fr) 2006-07-27
PL1845978T3 (pl) 2011-02-28
CY1110926T1 (el) 2015-06-10
IL184524A0 (en) 2007-10-31
EP1845978A1 (fr) 2007-10-24
HRP20100624T1 (hr) 2010-12-31
CA2595041A1 (fr) 2006-07-27
JP2008527025A (ja) 2008-07-24
US8008322B2 (en) 2011-08-30
PT1845978E (pt) 2010-11-29
PE20061119A1 (es) 2006-11-27
US20110190337A1 (en) 2011-08-04
DK1845978T3 (da) 2010-12-13
TW200639173A (en) 2006-11-16
RU2375360C2 (ru) 2009-12-10
UY29341A1 (es) 2006-08-31
SI1845978T1 (sl) 2010-12-31
HRP20100624T8 (en) 2011-01-31
KR20070098923A (ko) 2007-10-05
AU2006207442A1 (en) 2006-07-27

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