[go: up one dir, main page]

PA8652001A1 - Metabolitos glucuronidos de tigeciclina y epimeros de los mismos - Google Patents

Metabolitos glucuronidos de tigeciclina y epimeros de los mismos

Info

Publication number
PA8652001A1
PA8652001A1 PA20058652001A PA8652001A PA8652001A1 PA 8652001 A1 PA8652001 A1 PA 8652001A1 PA 20058652001 A PA20058652001 A PA 20058652001A PA 8652001 A PA8652001 A PA 8652001A PA 8652001 A1 PA8652001 A1 PA 8652001A1
Authority
PA
Panama
Prior art keywords
tigecicline
glucuronid
metabolites
same
metabolite
Prior art date
Application number
PA20058652001A
Other languages
English (en)
Inventor
Ronald A Jordan
William Demaio
Matthew Hoffmann
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PA8652001A1 publication Critical patent/PA8652001A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

UN METABOLITO GLUCURONIDO DE TIGECICLINA Y SU CORRESPONDIENTE EPIMERO SE HAN IDENTIFICADO EN SERES HUMANOS TRATADOS CON TIGECICLINA. LOS DATOS DE ESPECTROSCOPIS DE MASAS SE HAN EMPLEADO PARA IDENTIFICART ESTAS ESTRUCTURAS.
PA20058652001A 2004-11-05 2005-11-02 Metabolitos glucuronidos de tigeciclina y epimeros de los mismos PA8652001A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62512104P 2004-11-05 2004-11-05

Publications (1)

Publication Number Publication Date
PA8652001A1 true PA8652001A1 (es) 2006-10-13

Family

ID=36337018

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20058652001A PA8652001A1 (es) 2004-11-05 2005-11-02 Metabolitos glucuronidos de tigeciclina y epimeros de los mismos

Country Status (22)

Country Link
US (1) US7534766B2 (es)
EP (1) EP1807441A2 (es)
JP (1) JP2008519038A (es)
KR (1) KR20070085761A (es)
CN (1) CN101132799A (es)
AR (1) AR051236A1 (es)
AU (1) AU2005304957A1 (es)
BR (1) BRPI0517715A (es)
CA (1) CA2586245A1 (es)
CR (1) CR9111A (es)
GT (1) GT200500320A (es)
HN (1) HN2005030775A (es)
IL (1) IL182640A0 (es)
MX (1) MX2007005105A (es)
NO (1) NO20072226L (es)
PA (1) PA8652001A1 (es)
PE (1) PE20061048A1 (es)
RU (1) RU2007116800A (es)
SV (1) SV2006002294A (es)
TW (1) TW200628485A (es)
WO (1) WO2006052717A2 (es)
ZA (1) ZA200703624B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2695259C (en) * 2007-07-31 2016-05-24 Gilead Colorado, Inc. Metabolites and derivatives of ambrisentan
US8766177B2 (en) * 2010-10-11 2014-07-01 University Of North Texas Nanomanipulation coupled nanospray mass spectrometry (NMS)
JP6134191B2 (ja) 2013-04-07 2017-05-24 村川 惠美 回転型セミバッチａｌｄ装置

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0536515T3 (da) 1991-10-04 2002-04-08 American Cyanamid Co Nye 7-substitueret-9-substitueret amino-6-demethyl-6-deoxytetracycliner
US5494903A (en) * 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US5284963A (en) 1992-08-13 1994-02-08 American Cyanamid Company Method of producing 7-(substituted)-9-[(substituted glycyl)-amidol]-6-demethyl-6-deoxytetra-cyclines
US5328902A (en) 1992-08-13 1994-07-12 American Cyanamid Co. 7-(substituted)-9-[(substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
US5420272A (en) 1992-08-13 1995-05-30 American Cyanamid Company 7-(substituted)-8-(substituted)-9-](substituted glycyl)amido]-6-demethyl-6-deoxytetracyclines
SG47520A1 (en) 1992-08-13 1998-04-17 American Cyanamid Co New method for the production of 9-amino-6-demethyl-6-deoxytetracycline
EP1656341A1 (en) 2003-07-09 2006-05-17 Paratek Pharmaceuticals, Inc. Prodrugs of 9-aminomethyl tetracycline compounds
EP2295404A3 (en) 2003-07-09 2011-05-11 Paratek Pharmaceuticals, Inc. Substituted tetracycline compounds
US20050148553A1 (en) * 2003-09-05 2005-07-07 Testa Raymond T. Use of tigecycline, alone, or in combination with rifampin to treat osteomyelitis and/or septic arthritis

Also Published As

Publication number Publication date
US20060128950A1 (en) 2006-06-15
WO2006052717A3 (en) 2007-11-15
AU2005304957A1 (en) 2006-05-18
ZA200703624B (en) 2009-10-28
SV2006002294A (es) 2006-10-13
BRPI0517715A (pt) 2008-10-21
JP2008519038A (ja) 2008-06-05
CR9111A (es) 2008-01-21
NO20072226L (no) 2007-06-04
US7534766B2 (en) 2009-05-19
KR20070085761A (ko) 2007-08-27
RU2007116800A (ru) 2008-12-10
IL182640A0 (en) 2007-07-24
HN2005030775A (es) 2006-12-18
AR051236A1 (es) 2006-12-27
CA2586245A1 (en) 2006-05-18
EP1807441A2 (en) 2007-07-18
MX2007005105A (es) 2007-06-26
GT200500320A (es) 2006-06-02
CN101132799A (zh) 2008-02-27
PE20061048A1 (es) 2006-11-15
TW200628485A (en) 2006-08-16
WO2006052717A2 (en) 2006-05-18

Similar Documents

Publication Publication Date Title
NL1024643A1 (nl) Purineverbindingen en gebruik daarvan.
CL2004001473A1 (es) Procedimiento para producir neuronas desde celulas mesenquimatosas no diferenciadas y composicion que las contiene.
IS2736B (is) Makrólíðsamrunaefnasambönd@með@bólgueyðandi@virkni
BRPI0519710A2 (pt) aminoÁlcoois tricÍclicos, processo para sua preparaÇço e seu emprego como anti-inflamatàrio
BRPI0510938A (pt) vitamina k1 como energizador em formulações cosméticas
PA8652001A1 (es) Metabolitos glucuronidos de tigeciclina y epimeros de los mismos
DE602005023401D1 (de) Mechanische Vorrichtung mit NOx Speicher- und Umsetzungkalalysator
DE602004028589D1 (de) Verbesserungen an haut-prick-geräten
EP1856973A4 (en) SOLUTION FOR MAINTAINING AND IMPROVING ORGAN FUNCTION
EP1589033A4 (en) ANTIBODY AND ITS USE
FI20030478L (fi) Pysäköintiin liityvien tietojen välittäminen käyttäjälle
ITMI20052450A1 (it) Estratti di phaseolus vulgaris loro uso e formulazioni che li contengono
ITMO20050002A1 (it) Valigetta porta attrezzi minuterie e relativo sviluppo piano.
FI20020799A0 (fi) Voimalaite
EP4303025A4 (en) FAST-ACTING PORTABLE INK STAMP
ITMI20052451A1 (it) Estratti di phaseolus vulgaris loro uso e formulazioni che li contengono
ES1051801Y (es) Proyector de juguete portatil para dibujar.
ES1056785Y (es) Instrumento para hacer pentagramas.
ES1051298Y (es) Dispositivo con efecto sonoro adaptado a pin.
ES1052439Y (es) Muñeco con dispositivo para realizacion de gestos.
IT255864Z2 (it) Mixer con metronomo incorporato.
FI20041394A0 (fi) Kellopelihiiret
BRPI0408791B1 (pt) Artigo de poliuretano de cor preta e métodos para produzir o mesmo
ES1057233Y (es) Bascula con tallimetro y con tensiometro incorporado
EP1944323A4 (en) NEW MONOCLONAL ANTIBODY AND APPLICATION THEREOF