PA8463001A1 - Compuestos de eteres ciclicos de piperidinilaminometil trifluorometilo como antagonistas de la sustancia p - Google Patents
Compuestos de eteres ciclicos de piperidinilaminometil trifluorometilo como antagonistas de la sustancia pInfo
- Publication number
- PA8463001A1 PA8463001A1 PA19988463001A PA8463001A PA8463001A1 PA 8463001 A1 PA8463001 A1 PA 8463001A1 PA 19988463001 A PA19988463001 A PA 19988463001A PA 8463001 A PA8463001 A PA 8463001A PA 8463001 A1 PA8463001 A1 PA 8463001A1
- Authority
- PA
- Panama
- Prior art keywords
- compounds
- diseases
- eters
- antagonists
- cyclic
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Reproductive Health (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Vascular Medicine (AREA)
- Communicable Diseases (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
ESTA INVENCION PROPORCIONA UN COMPUESTO DE FORMULA Y SUS SALES FARMACEUTICAMENTE ACEPTABLES, EN LA QUE R1 ES ALQUILO C1-C6; R2 ES HIDROGENO, ALQUILO C1-C6, HALOALQUILO C1-C6 O FENILO; R3 ES HIDROGENO O HALOGENO; R4 Y R5 SON INDEPENDIENTEMENTE HIDROGENO, ALQUILO C1-C6 O HALOALQUILO C1-C6; Y N ES UNO, DOS O TRES. ESTOS COMPUESTOS SON UTILES COMO ANALGESICOS O AGENTES ANTI- INFLAMATORIOS O PARA EL TRATAMIENTO DE ENFERMEDADES CARDIOVASCULARES, TRASTORNOS ALERGICOS, ANGIOGENESIS, TRASTORNOS DEL SNC, EMESIS, TRASTORNOS GASTROINTESTINALES, QUEMADURAS SOLARES, INCONTINENCIA URINARIA O ENFERMEDADES TRASTORNOS Y ALTERACIONES ADVERSAS PROVOCADAS POR HELICOBACTER PYLORI, O SIMILARES, EN UN MAMIFERO, ESPECIALMENTE UN SER HUMANO. TAMBIEN SE DESCRIBEN INTERMEDIOS PARA LA PREPARACION DE LOS COMPUESTOS DE FORMULA (1).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB9701466 | 1997-11-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PA8463001A1 true PA8463001A1 (es) | 2000-09-29 |
Family
ID=11004634
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PA19988463001A PA8463001A1 (es) | 1997-11-19 | 1998-11-11 | Compuestos de eteres ciclicos de piperidinilaminometil trifluorometilo como antagonistas de la sustancia p |
Country Status (40)
| Country | Link |
|---|---|
| US (2) | US20030208079A1 (es) |
| EP (1) | EP1032571B1 (es) |
| JP (2) | JP3394239B2 (es) |
| KR (1) | KR100366902B1 (es) |
| CN (1) | CN1173974C (es) |
| AP (1) | AP909A (es) |
| AR (1) | AR016422A1 (es) |
| AT (1) | ATE219078T1 (es) |
| AU (1) | AU734218B2 (es) |
| BG (1) | BG63969B1 (es) |
| CA (1) | CA2310627C (es) |
| CO (1) | CO4771153A1 (es) |
| CZ (1) | CZ297315B6 (es) |
| DE (1) | DE69806045T2 (es) |
| DK (1) | DK1032571T3 (es) |
| DZ (1) | DZ2655A1 (es) |
| EA (1) | EA002621B1 (es) |
| ES (1) | ES2177058T3 (es) |
| HK (1) | HK1033313A1 (es) |
| HR (1) | HRP20000313B1 (es) |
| HU (1) | HUP0101112A3 (es) |
| ID (1) | ID24240A (es) |
| IL (1) | IL135631A0 (es) |
| IS (1) | IS2202B (es) |
| MA (1) | MA26567A1 (es) |
| MY (1) | MY120558A (es) |
| NO (2) | NO20002544L (es) |
| NZ (1) | NZ503912A (es) |
| OA (1) | OA11380A (es) |
| PA (1) | PA8463001A1 (es) |
| PE (1) | PE20000021A1 (es) |
| PL (1) | PL193484B1 (es) |
| PT (1) | PT1032571E (es) |
| RS (1) | RS49792B (es) |
| SK (1) | SK283460B6 (es) |
| TN (1) | TNSN98210A1 (es) |
| TR (1) | TR200001463T2 (es) |
| TW (1) | TW426667B (es) |
| UA (1) | UA59417C2 (es) |
| WO (1) | WO1999025714A1 (es) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9812662D0 (en) * | 1998-06-11 | 1998-08-12 | Merck Sharp & Dohme | Therapeutic use |
| GB9812617D0 (en) * | 1998-06-11 | 1998-08-12 | Merck Sharp & Dohme | Therapeutic use |
| AU3572800A (en) * | 1999-05-06 | 2000-11-21 | Pfizer Products Inc. | Substituted benzolactam compounds |
| RS49964B (sr) | 1999-05-17 | 2008-09-29 | Pfizer Products Inc., | Postupak za dobijanje 2-fenil-3-aminopiridina,njegovih supstituisanih fenil derivata, i njegovih soli |
| PT1178984E (pt) * | 1999-05-21 | 2003-06-30 | Pfizer Prod Inc | Derivados de 1-trifluorometil-4-hidroxi-7-piperidinilamimometilcromano |
| EP1219619B1 (en) * | 1999-10-07 | 2004-08-11 | Hisamitsu Pharmaceutical Co. Inc. | 3-amino-2-phenylpiperidine derivatives as substance p antagonists |
| DK1095939T3 (da) * | 1999-10-18 | 2004-04-13 | Pfizer Prod Inc | Fremgangsmåde til fremstilling af cykliske piperidinylaminomethyltrifluormethyletherforbindelser |
| JP2001172178A (ja) * | 1999-10-25 | 2001-06-26 | Pfizer Prod Inc | 偏頭痛治療用のｎｋ−１レセプターアンタゴニスト及びエレトリプタン |
| IL142810A0 (en) * | 2000-05-03 | 2002-03-10 | Pfizer Prod Inc | Pharmaceutical uses for fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles |
| US20020049211A1 (en) * | 2000-09-06 | 2002-04-25 | Sobolov-Jaynes Susan Beth | Combination treatment for depression and anxiety |
| EP1192952A3 (en) * | 2000-09-28 | 2003-03-26 | Pfizer Products Inc. | Combination, for treating depression and anxiety, containing an NK-3 receptor antagonist and a CNS penetrant NK-1 receptor antagonist |
| US6555581B1 (en) | 2001-02-15 | 2003-04-29 | Jones Pharma, Inc. | Levothyroxine compositions and methods |
| EP1365745A2 (en) | 2001-02-15 | 2003-12-03 | King Pharmaceuticals, Inc. | Stabilized pharmaceutical and thyroid hormone compositions and method of preparation |
| US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
| DE60213043T2 (de) | 2001-08-30 | 2007-01-04 | Pfizer Products Inc., Groton | Verfahren zur Herstellung von 2-(4-Alkyl-1-Piperazinyl)-Benzaldehyd und -Benzylidenyl-Derivaten durch Nucleophile Substitution von 2-Fluorobenzaldehyd mit 4-Alkyl-1-Piperazinen in Wasser als Lösungsmittel |
| US20040001895A1 (en) * | 2002-06-17 | 2004-01-01 | Pfizer Inc. | Combination treatment for depression and anxiety |
| US20070207123A1 (en) * | 2002-08-27 | 2007-09-06 | Witten Mark L | Amelioration of effects of cigarette smoke |
| US6911544B2 (en) * | 2002-10-23 | 2005-06-28 | Pfizer Inc. | Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine |
| US7122700B2 (en) | 2004-07-30 | 2006-10-17 | Xerox Corporation | Arylamine processes |
| DE102008000891A1 (de) | 2008-03-31 | 2009-10-01 | Robert Bosch Gmbh | Schutzsystem für Werkzeugmaschinen |
| EP2729147B1 (en) | 2011-07-04 | 2017-09-06 | IRBM - Science Park S.p.A. | Nk-1 receptor antagonists for treating corneal neovascularisation |
| RU2020131446A (ru) | 2018-02-26 | 2022-03-28 | Оспедале Сан Раффаэле С.Р.Л. | Антагонисты nk-1 для применения в лечении глазной боли |
| EP4117673A1 (en) | 2020-03-11 | 2023-01-18 | Ospedale San Raffaele S.r.l. | Treatment of stem cell deficiency |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9317987D0 (en) * | 1993-08-26 | 1993-10-13 | Glaxo Group Ltd | Chemical compounds |
| KR19980703354A (ko) * | 1995-03-27 | 1998-10-15 | 나카토미히로타카 | 피페리딘 유도체 |
| TW475930B (en) * | 1995-04-24 | 2002-02-11 | Novartis Ag | Novel compound, its use and pharmaceutical composition comprising it |
| CA2226292C (en) * | 1995-07-07 | 2001-12-11 | Pfizer Inc. | Substituted benzolactam compounds as substance p antagonists |
| TW340842B (en) * | 1995-08-24 | 1998-09-21 | Pfizer | Substituted benzylaminopiperidine compounds |
| US6329396B1 (en) * | 1996-06-10 | 2001-12-11 | Pfizer Inc. | Substituted benzylaminopiperidine compounds |
| PT1178984E (pt) * | 1999-05-21 | 2003-06-30 | Pfizer Prod Inc | Derivados de 1-trifluorometil-4-hidroxi-7-piperidinilamimometilcromano |
| DK1095939T3 (da) * | 1999-10-18 | 2004-04-13 | Pfizer Prod Inc | Fremgangsmåde til fremstilling af cykliske piperidinylaminomethyltrifluormethyletherforbindelser |
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1998
- 1998-10-21 TW TW087117444A patent/TW426667B/zh not_active IP Right Cessation
- 1998-10-26 NZ NZ503912A patent/NZ503912A/xx unknown
- 1998-10-26 TR TR2000/01463T patent/TR200001463T2/xx unknown
- 1998-10-26 AT AT98947726T patent/ATE219078T1/de not_active IP Right Cessation
- 1998-10-26 EP EP98947726A patent/EP1032571B1/en not_active Expired - Lifetime
- 1998-10-26 UA UA2000042374A patent/UA59417C2/uk unknown
- 1998-10-26 CN CNB988112930A patent/CN1173974C/zh not_active Expired - Fee Related
- 1998-10-26 JP JP2000521096A patent/JP3394239B2/ja not_active Expired - Fee Related
- 1998-10-26 CZ CZ20001834A patent/CZ297315B6/cs not_active IP Right Cessation
- 1998-10-26 RS YUP-294/00A patent/RS49792B/sr unknown
- 1998-10-26 EA EA200000432A patent/EA002621B1/ru not_active IP Right Cessation
- 1998-10-26 AU AU94549/98A patent/AU734218B2/en not_active Ceased
- 1998-10-26 DK DK98947726T patent/DK1032571T3/da active
- 1998-10-26 ES ES98947726T patent/ES2177058T3/es not_active Expired - Lifetime
- 1998-10-26 SK SK723-2000A patent/SK283460B6/sk unknown
- 1998-10-26 IL IL13563198A patent/IL135631A0/xx not_active IP Right Cessation
- 1998-10-26 WO PCT/IB1998/001704 patent/WO1999025714A1/en active IP Right Grant
- 1998-10-26 HU HU0101112A patent/HUP0101112A3/hu unknown
- 1998-10-26 DE DE69806045T patent/DE69806045T2/de not_active Expired - Fee Related
- 1998-10-26 PT PT98947726T patent/PT1032571E/pt unknown
- 1998-10-26 CA CA002310627A patent/CA2310627C/en not_active Expired - Fee Related
- 1998-10-26 ID IDW20000926A patent/ID24240A/id unknown
- 1998-11-11 PA PA19988463001A patent/PA8463001A1/es unknown
- 1998-11-16 PE PE1998001112A patent/PE20000021A1/es not_active Application Discontinuation
- 1998-11-17 AR ARP980105829A patent/AR016422A1/es unknown
- 1998-11-17 MY MYPI98005209A patent/MY120558A/en unknown
- 1998-11-17 MA MA25354A patent/MA26567A1/fr unknown
- 1998-11-18 TN TNTNSN98210A patent/TNSN98210A1/fr unknown
- 1998-11-18 CO CO98067902A patent/CO4771153A1/es unknown
- 1998-11-18 DZ DZ980265A patent/DZ2655A1/xx active
- 1998-11-19 AP APAP/P/1998/001402A patent/AP909A/en active
-
2000
- 2000-04-26 IS IS5470A patent/IS2202B/is unknown
- 2000-05-12 OA OA1200000138A patent/OA11380A/en unknown
- 2000-05-15 BG BG104437A patent/BG63969B1/bg unknown
- 2000-05-17 HR HR960576A patent/HRP20000313B1/xx not_active IP Right Cessation
- 2000-05-18 NO NO20002544A patent/NO20002544L/no not_active Application Discontinuation
- 2000-05-18 PL PL98340642A patent/PL193484B1/pl unknown
- 2000-05-18 KR KR10-2000-7005431A patent/KR100366902B1/ko not_active IP Right Cessation
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2001
- 2001-06-08 HK HK01103947A patent/HK1033313A1/xx not_active IP Right Cessation
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2002
- 2002-06-18 JP JP2002177452A patent/JP2003040777A/ja active Pending
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2003
- 2003-04-21 US US10/419,425 patent/US20030208079A1/en not_active Abandoned
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2004
- 2004-07-07 NO NO20042879A patent/NO20042879L/no not_active Application Discontinuation
- 2004-11-18 US US10/991,977 patent/US20050171354A1/en not_active Abandoned
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