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NZ734644A - Chemically encoded spatially addressed library screening platforms - Google Patents

Chemically encoded spatially addressed library screening platforms

Info

Publication number
NZ734644A
NZ734644A NZ734644A NZ73464416A NZ734644A NZ 734644 A NZ734644 A NZ 734644A NZ 734644 A NZ734644 A NZ 734644A NZ 73464416 A NZ73464416 A NZ 73464416A NZ 734644 A NZ734644 A NZ 734644A
Authority
NZ
New Zealand
Prior art keywords
ligand domain
linker
library screening
spatially addressed
attached
Prior art date
Application number
NZ734644A
Inventor
Jacob Berlin
Gregory COPELAND
Kathleen Elison
Hurik Muradyan
Original Assignee
Hope City
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=56789474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ734644(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hope City filed Critical Hope City
Priority to NZ772386A priority Critical patent/NZ772386A/en
Publication of NZ734644A publication Critical patent/NZ734644A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
    • C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
    • C40B50/16—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support involving encoding steps
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/04—Libraries containing only organic compounds
    • C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Plant Pathology (AREA)
  • Structural Engineering (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Signal Processing For Digital Recording And Reproducing (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

Provided herein are highly diverse and dense arrays of immobilized microparticles having attached ligand domain molecules for screening and detection of a variety of ligand domain-binding molecules. Also provided herein are methods for forming, decoding, and mapping highly diverse and dense arrays of immobilized microparticles having attached ligand domain molecules for screening and detection of a variety of ligand domain-binding molecules. The microparticles are attached to a ligand domain through a first linker and a nucleic acid domain through a second linker. The second linker comprises an acyl group or a sulfonamide group and is cleavable under conditions that do not cleave the first linker.
NZ734644A 2015-02-24 2016-02-24 Chemically encoded spatially addressed library screening platforms NZ734644A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ772386A NZ772386A (en) 2015-02-24 2016-02-24 Chemically encoded spatially addressed library screening platforms

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562120262P 2015-02-24 2015-02-24
PCT/US2016/019426 WO2016138184A1 (en) 2015-02-24 2016-02-24 Chemically encoded spatially addressed library screening platforms

Publications (1)

Publication Number Publication Date
NZ734644A true NZ734644A (en) 2023-02-24

Family

ID=56789474

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ772386A NZ772386A (en) 2015-02-24 2016-02-24 Chemically encoded spatially addressed library screening platforms
NZ734644A NZ734644A (en) 2015-02-24 2016-02-24 Chemically encoded spatially addressed library screening platforms

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NZ772386A NZ772386A (en) 2015-02-24 2016-02-24 Chemically encoded spatially addressed library screening platforms

Country Status (19)

Country Link
US (6) US10760181B2 (en)
EP (4) EP4276059A3 (en)
JP (2) JP6872501B2 (en)
AU (2) AU2016222755B2 (en)
CA (1) CA2976946C (en)
CY (1) CY1124954T1 (en)
DK (3) DK3650458T5 (en)
ES (3) ES2965764T3 (en)
FI (2) FI3650458T3 (en)
HR (3) HRP20231536T1 (en)
HU (3) HUE058813T2 (en)
LT (3) LT3650459T (en)
NZ (2) NZ772386A (en)
PL (3) PL3650458T3 (en)
PT (3) PT3262059T (en)
RS (3) RS62847B1 (en)
SI (3) SI3650459T1 (en)
SM (3) SMT202300430T1 (en)
WO (1) WO2016138184A1 (en)

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CA2976946C (en) * 2015-02-24 2023-09-19 City Of Hope Chemically encoded spatially addressed library screening platforms
CN106048736B (en) * 2015-04-14 2019-09-03 成都先导药物开发股份有限公司 A kind of method of synthesis in solid state DNA encoding compound library
CA3042974A1 (en) * 2016-11-08 2018-05-17 David Hugh Williams Tagless encoded chemical library
US20190210018A1 (en) 2017-09-25 2019-07-11 Plexium, Inc. Oligonucleotide encoded chemical libraries
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WO2022170034A1 (en) * 2021-02-05 2022-08-11 Affinergy, Llc Rapid assay for apol1 g0 protein
JP7502835B2 (en) * 2021-08-27 2024-06-19 国立大学法人神戸大学 Core-shell template molecules and particles for efficient formation of pores on substrates

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Also Published As

Publication number Publication date
CA2976946A1 (en) 2016-09-01
EP3650458A1 (en) 2020-05-13
JP2021106607A (en) 2021-07-29
HUE063406T2 (en) 2024-01-28
HUE058813T2 (en) 2022-09-28
US10760181B2 (en) 2020-09-01
AU2016222755B2 (en) 2021-02-18
EP3262059A1 (en) 2018-01-03
JP6872501B2 (en) 2021-05-19
US20210324538A1 (en) 2021-10-21
FI3650459T3 (en) 2023-11-28
SMT202300275T1 (en) 2023-11-13
US20200378032A1 (en) 2020-12-03
WO2016138184A1 (en) 2016-09-01
EP4276059A2 (en) 2023-11-15
US20180245241A1 (en) 2018-08-30
AU2021200399A1 (en) 2021-03-18
SI3262059T1 (en) 2022-04-29
HUE064689T2 (en) 2024-04-28
SMT202300430T1 (en) 2024-01-10
PL3262059T3 (en) 2022-02-21
PT3650459T (en) 2023-12-06
JP2018505700A (en) 2018-03-01
US20190390367A1 (en) 2019-12-26
ES2965764T3 (en) 2024-04-16
EP3650459A1 (en) 2020-05-13
LT3650459T (en) 2023-12-27
EP4276059A3 (en) 2024-05-01
ES2954467T3 (en) 2023-11-22
ES2904997T3 (en) 2022-04-06
DK3650459T3 (en) 2023-12-11
US11015266B2 (en) 2021-05-25
US20200378031A1 (en) 2020-12-03
PT3262059T (en) 2022-01-27
EP3650458B1 (en) 2023-08-09
JP7109618B6 (en) 2022-08-22
SI3650459T1 (en) 2024-04-30
DK3262059T3 (en) 2022-01-31
NZ772386A (en) 2024-10-25
RS64899B1 (en) 2023-12-29
LT3650458T (en) 2023-10-10
US10767278B2 (en) 2020-09-08
CY1124954T1 (en) 2023-01-05
LT3262059T (en) 2022-02-25
AU2016222755A1 (en) 2017-08-31
DK3650459T5 (en) 2024-08-26
EP3650459B1 (en) 2023-09-06
SMT202200039T1 (en) 2022-03-21
EP3262059A4 (en) 2018-12-05
FI3650458T3 (en) 2023-08-21
US11015265B2 (en) 2021-05-25
PL3650458T3 (en) 2023-11-06
RS62847B1 (en) 2022-02-28
DK3650458T5 (en) 2024-08-26
DK3650458T3 (en) 2023-09-04
HRP20231536T1 (en) 2024-03-15
HRP20230928T1 (en) 2023-11-24
EP3262059B1 (en) 2022-01-05
JP7109618B2 (en) 2022-07-29
PL3650459T3 (en) 2024-02-26
CA2976946C (en) 2023-09-19
SI3650458T1 (en) 2023-11-30
HRP20220093T1 (en) 2022-04-15
AU2021200399B2 (en) 2023-04-20
US20220341059A1 (en) 2022-10-27
PT3650458T (en) 2023-08-31
RS64567B1 (en) 2023-10-31

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