NZ734644A - Chemically encoded spatially addressed library screening platforms - Google Patents
Chemically encoded spatially addressed library screening platformsInfo
- Publication number
- NZ734644A NZ734644A NZ734644A NZ73464416A NZ734644A NZ 734644 A NZ734644 A NZ 734644A NZ 734644 A NZ734644 A NZ 734644A NZ 73464416 A NZ73464416 A NZ 73464416A NZ 734644 A NZ734644 A NZ 734644A
- Authority
- NZ
- New Zealand
- Prior art keywords
- ligand domain
- linker
- library screening
- spatially addressed
- attached
- Prior art date
Links
- 238000012216 screening Methods 0.000 title abstract 3
- 239000003446 ligand Substances 0.000 abstract 5
- 239000011859 microparticle Substances 0.000 abstract 3
- 238000003491 array Methods 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 238000013507 mapping Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 125000000565 sulfonamide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
- C40B50/16—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support involving encoding steps
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/10—Libraries containing peptides or polypeptides, or derivatives thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54326—Magnetic particles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
- G01N33/54346—Nanoparticles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Structural Engineering (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Signal Processing For Digital Recording And Reproducing (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Provided herein are highly diverse and dense arrays of immobilized microparticles having attached ligand domain molecules for screening and detection of a variety of ligand domain-binding molecules. Also provided herein are methods for forming, decoding, and mapping highly diverse and dense arrays of immobilized microparticles having attached ligand domain molecules for screening and detection of a variety of ligand domain-binding molecules. The microparticles are attached to a ligand domain through a first linker and a nucleic acid domain through a second linker. The second linker comprises an acyl group or a sulfonamide group and is cleavable under conditions that do not cleave the first linker.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NZ772386A NZ772386B2 (en) | 2016-02-24 | Chemically encoded spatially addressed library screening platforms |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562120262P | 2015-02-24 | 2015-02-24 | |
| PCT/US2016/019426 WO2016138184A1 (en) | 2015-02-24 | 2016-02-24 | Chemically encoded spatially addressed library screening platforms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ734644A true NZ734644A (en) | 2023-02-24 |
Family
ID=56789474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ734644A NZ734644A (en) | 2015-02-24 | 2016-02-24 | Chemically encoded spatially addressed library screening platforms |
Country Status (19)
| Country | Link |
|---|---|
| US (6) | US10760181B2 (en) |
| EP (4) | EP3650459B1 (en) |
| JP (2) | JP6872501B2 (en) |
| AU (2) | AU2016222755B2 (en) |
| CA (1) | CA2976946C (en) |
| CY (1) | CY1124954T1 (en) |
| DK (3) | DK3262059T3 (en) |
| ES (3) | ES2965764T3 (en) |
| FI (2) | FI3650459T3 (en) |
| HR (3) | HRP20230928T1 (en) |
| HU (3) | HUE063406T2 (en) |
| LT (3) | LT3262059T (en) |
| NZ (1) | NZ734644A (en) |
| PL (3) | PL3650458T3 (en) |
| PT (3) | PT3650458T (en) |
| RS (3) | RS64899B1 (en) |
| SI (3) | SI3262059T1 (en) |
| SM (3) | SMT202200039T1 (en) |
| WO (1) | WO2016138184A1 (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2622112B2 (en) | 1986-09-26 | 1997-06-18 | キヤノン株式会社 | Image processing system |
| WO2009069203A1 (en) * | 2007-11-28 | 2009-06-04 | Glory Ltd. | Ticket processing device, ticket processing system and ticket processing method |
| WO2016138184A1 (en) | 2015-02-24 | 2016-09-01 | City Of Hope | Chemically encoded spatially addressed library screening platforms |
| WO2016165621A1 (en) * | 2015-04-14 | 2016-10-20 | 成都先导药物开发有限公司 | Method for solid-phase synthesis of dna-encoded chemical library |
| CN110249050B (en) * | 2016-11-08 | 2023-08-18 | 南纳治疗有限公司 | Library of non-tag encoded compounds |
| US20190210018A1 (en) | 2017-09-25 | 2019-07-11 | Plexium, Inc. | Oligonucleotide encoded chemical libraries |
| AU2018358247A1 (en) | 2017-10-31 | 2020-05-21 | Encodia, Inc. | Methods and kits using nucleic acid encoding and/or label |
| KR20220097404A (en) | 2019-10-10 | 2022-07-07 | 1859, 인크. | Methods and systems for microfluidic screening |
| WO2022170034A1 (en) * | 2021-02-05 | 2022-08-11 | Affinergy, Llc | Rapid assay for apol1 g0 protein |
| JP7502835B2 (en) * | 2021-08-27 | 2024-06-19 | 国立大学法人神戸大学 | Core-shell template molecules and particles for efficient formation of pores on substrates |
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2016
- 2016-02-24 WO PCT/US2016/019426 patent/WO2016138184A1/en not_active Ceased
- 2016-02-24 PT PT191960079T patent/PT3650458T/en unknown
- 2016-02-24 FI FIEP19196019.4T patent/FI3650459T3/en active
- 2016-02-24 DK DK16756316.2T patent/DK3262059T3/en active
- 2016-02-24 HR HRP20230928TT patent/HRP20230928T1/en unknown
- 2016-02-24 AU AU2016222755A patent/AU2016222755B2/en active Active
- 2016-02-24 SM SM20220039T patent/SMT202200039T1/en unknown
- 2016-02-24 HR HRP20220093TT patent/HRP20220093T1/en unknown
- 2016-02-24 SI SI201631454T patent/SI3262059T1/en unknown
- 2016-02-24 PL PL19196007.9T patent/PL3650458T3/en unknown
- 2016-02-24 SI SI201631737T patent/SI3650458T1/en unknown
- 2016-02-24 FI FIEP19196007.9T patent/FI3650458T3/en active
- 2016-02-24 EP EP19196019.4A patent/EP3650459B1/en active Active
- 2016-02-24 EP EP16756316.2A patent/EP3262059B1/en active Active
- 2016-02-24 ES ES19196019T patent/ES2965764T3/en active Active
- 2016-02-24 LT LTEPPCT/US2016/019426T patent/LT3262059T/en unknown
- 2016-02-24 CA CA2976946A patent/CA2976946C/en active Active
- 2016-02-24 LT LTEP19196019.4T patent/LT3650459T/en unknown
- 2016-02-24 SM SM20230275T patent/SMT202300275T1/en unknown
- 2016-02-24 PL PL19196019.4T patent/PL3650459T3/en unknown
- 2016-02-24 NZ NZ734644A patent/NZ734644A/en unknown
- 2016-02-24 SM SM20230430T patent/SMT202300430T1/en unknown
- 2016-02-24 EP EP23195322.5A patent/EP4276059A3/en active Pending
- 2016-02-24 HR HRP20231536TT patent/HRP20231536T1/en unknown
- 2016-02-24 DK DK19196019.4T patent/DK3650459T5/en active
- 2016-02-24 HU HUE19196007A patent/HUE063406T2/en unknown
- 2016-02-24 ES ES16756316T patent/ES2904997T3/en active Active
- 2016-02-24 PT PT167563162T patent/PT3262059T/en unknown
- 2016-02-24 RS RS20231135A patent/RS64899B1/en unknown
- 2016-02-24 EP EP19196007.9A patent/EP3650458B1/en active Active
- 2016-02-24 PL PL16756316T patent/PL3262059T3/en unknown
- 2016-02-24 JP JP2017562972A patent/JP6872501B2/en active Active
- 2016-02-24 US US15/553,140 patent/US10760181B2/en active Active
- 2016-02-24 PT PT191960194T patent/PT3650459T/en unknown
- 2016-02-24 LT LTEP19196007.9T patent/LT3650458T/en unknown
- 2016-02-24 RS RS20220051A patent/RS62847B1/en unknown
- 2016-02-24 ES ES19196007T patent/ES2954467T3/en active Active
- 2016-02-24 SI SI201631770T patent/SI3650459T1/en unknown
- 2016-02-24 RS RS20230660A patent/RS64567B1/en unknown
- 2016-02-24 DK DK19196007.9T patent/DK3650458T5/en active
- 2016-02-24 HU HUE19196019A patent/HUE064689T2/en unknown
- 2016-02-24 HU HUE16756316A patent/HUE058813T2/en unknown
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2019
- 2019-08-29 US US16/555,531 patent/US10767278B2/en active Active
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2020
- 2020-07-28 US US16/940,499 patent/US11015265B2/en active Active
- 2020-07-30 US US16/943,630 patent/US11015266B2/en active Active
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2021
- 2021-01-21 AU AU2021200399A patent/AU2021200399B2/en active Active
- 2021-04-15 JP JP2021068860A patent/JP7109618B6/en active Active
- 2021-04-22 US US17/238,150 patent/US20210324538A1/en active Pending
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2022
- 2022-01-21 CY CY20221100054T patent/CY1124954T1/en unknown
- 2022-06-21 US US17/845,949 patent/US20220341059A1/en active Pending
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PSEA | Patent sealed | ||
| RENW | Renewal (renewal fees accepted) |
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