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NZ714079A - Purification process for monoclonal antibodies - Google Patents

Purification process for monoclonal antibodies

Info

Publication number
NZ714079A
NZ714079A NZ714079A NZ71407914A NZ714079A NZ 714079 A NZ714079 A NZ 714079A NZ 714079 A NZ714079 A NZ 714079A NZ 71407914 A NZ71407914 A NZ 71407914A NZ 714079 A NZ714079 A NZ 714079A
Authority
NZ
New Zealand
Prior art keywords
monoclonal antibodies
purification process
monoclonal antibody
purification
provides
Prior art date
Application number
NZ714079A
Inventor
Sanjeev Kumar Mendiratta
Sanjay Bandyopadhyay
Avanish Kumar Singh
Original Assignee
Cadila Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51655799&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ714079(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cadila Healthcare Ltd filed Critical Cadila Healthcare Ltd
Publication of NZ714079A publication Critical patent/NZ714079A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)

Abstract

The present invention provides an improved method for the purification of monoclonal antibody from cell culture. Process of purification of the desired monoclonal antibody comprises affinity, hydrophobic interaction and optionally ion exchange column chromatography. It provides more than 99% purity of the desired monoclonal antibody.
NZ714079A 2013-06-25 2014-06-25 Purification process for monoclonal antibodies NZ714079A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2145MU2013 IN2013MU02145A (en) 2013-06-25 2014-06-25
PCT/IN2014/000421 WO2014207763A1 (en) 2013-06-25 2014-06-25 Purification process for monoclonal antibodies

Publications (1)

Publication Number Publication Date
NZ714079A true NZ714079A (en) 2017-05-26

Family

ID=51655799

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ714079A NZ714079A (en) 2013-06-25 2014-06-25 Purification process for monoclonal antibodies

Country Status (19)

Country Link
US (1) US9708365B2 (en)
EP (1) EP3013849B1 (en)
JP (1) JP6039828B2 (en)
KR (1) KR101683415B1 (en)
CN (1) CN105263947A (en)
AR (1) AR096713A1 (en)
AU (1) AU2014300486B2 (en)
BR (1) BR112015031196A2 (en)
CA (1) CA2911874A1 (en)
EA (1) EA201592192A1 (en)
HK (1) HK1217344A1 (en)
IL (1) IL242649A (en)
IN (1) IN2013MU02145A (en)
MX (1) MX350610B (en)
NZ (1) NZ714079A (en)
SG (1) SG11201509502XA (en)
TW (1) TWI596107B (en)
WO (1) WO2014207763A1 (en)
ZA (1) ZA201508258B (en)

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CN111269316B (en) * 2018-12-04 2024-06-28 正大天晴药业集团南京顺欣制药有限公司 Method for purifying anti-HER 2 monoclonal antibody
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WO2021139720A1 (en) * 2020-01-08 2021-07-15 信达生物制药(苏州)有限公司 Purification method for adalimumab and stable composition thereof
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Also Published As

Publication number Publication date
EP3013849A1 (en) 2016-05-04
AR096713A1 (en) 2016-01-27
CA2911874A1 (en) 2014-12-31
AU2014300486B2 (en) 2016-06-30
KR101683415B1 (en) 2016-12-06
AU2014300486A1 (en) 2015-11-26
BR112015031196A2 (en) 2017-07-25
US9708365B2 (en) 2017-07-18
EA201592192A1 (en) 2016-07-29
JP6039828B2 (en) 2016-12-07
MX2015016586A (en) 2016-03-16
IL242649A (en) 2016-03-31
HK1217344A1 (en) 2017-01-06
KR20160003311A (en) 2016-01-08
MX350610B (en) 2017-09-11
JP2016525500A (en) 2016-08-25
US20160115195A1 (en) 2016-04-28
ZA201508258B (en) 2017-03-29
WO2014207763A1 (en) 2014-12-31
IN2013MU02145A (en) 2015-06-05
CN105263947A (en) 2016-01-20
SG11201509502XA (en) 2015-12-30
TW201512217A (en) 2015-04-01
EP3013849B1 (en) 2017-09-13
TWI596107B (en) 2017-08-21

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