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NZ609196A - Monoclonal antibodies against amyloid beta protein and uses thereof - Google Patents

Monoclonal antibodies against amyloid beta protein and uses thereof

Info

Publication number
NZ609196A
NZ609196A NZ609196A NZ60919606A NZ609196A NZ 609196 A NZ609196 A NZ 609196A NZ 609196 A NZ609196 A NZ 609196A NZ 60919606 A NZ60919606 A NZ 60919606A NZ 609196 A NZ609196 A NZ 609196A
Authority
NZ
New Zealand
Prior art keywords
seq
amyloid beta
beta protein
monoclonal antibodies
antibodies against
Prior art date
Application number
NZ609196A
Inventor
Boris Labkovsky
Andreas R Striebinger
Heinz Hillen
Ulrich Ebert
Stefan Barghorn
Patrick Keller
Original Assignee
Abbvie Inc
Abbvie Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc, Abbvie Deutschland filed Critical Abbvie Inc
Priority to NZ629387A priority Critical patent/NZ629387A/en
Publication of NZ609196A publication Critical patent/NZ609196A/en

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  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Disclosed is a monoclonal antibody comprising a variable heavy and light chain, wherein the three CDRs of said variable heavy chain are SEQ ID NO:5, SEQ ID NO:6 and SEQ ID NO:7, and the three CDRs of said variable light chain are SEQ ID NO:8, SEQ ID NO:9 and SEQ ID NO: 10, wherein the antibody binds with greater specificity to an amyloid beta protein globulomer than to an amyloid beta protein monomer, wherein the sequences are as defined in the complete specification. Also disclosed is the use of said antibody in the manufacture of a medicament for treating or preventing Alzheimer’s Disease. Further disclosed is a hybridoma having American Type Culture Collection designation number PTA-7238.
NZ609196A 2005-11-30 2006-11-30 Monoclonal antibodies against amyloid beta protein and uses thereof NZ609196A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ629387A NZ629387A (en) 2005-11-30 2006-11-30 Monoclonal antibodies against amyloid beta protein and uses thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74086605P 2005-11-30 2005-11-30
US77895006P 2006-03-03 2006-03-03
NZ59566806 2006-11-30

Publications (1)

Publication Number Publication Date
NZ609196A true NZ609196A (en) 2014-09-26

Family

ID=51582064

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ609196A NZ609196A (en) 2005-11-30 2006-11-30 Monoclonal antibodies against amyloid beta protein and uses thereof

Country Status (1)

Country Link
NZ (1) NZ609196A (en)

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