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NZ508660A - Methods and apparatus for ocular iontophoresis - Google Patents

Methods and apparatus for ocular iontophoresis

Info

Publication number
NZ508660A
NZ508660A NZ508660A NZ50866000A NZ508660A NZ 508660 A NZ508660 A NZ 508660A NZ 508660 A NZ508660 A NZ 508660A NZ 50866000 A NZ50866000 A NZ 50866000A NZ 508660 A NZ508660 A NZ 508660A
Authority
NZ
New Zealand
Prior art keywords
medicament
ocular iontophoresis
methods
barrier
current
Prior art date
Application number
NZ508660A
Inventor
Jon E Beck
Original Assignee
Iomed Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US09/318,181 priority Critical patent/US6319240B1/en
Priority to EP00123725A priority patent/EP1201265A1/en
Priority to CA002324779A priority patent/CA2324779A1/en
Priority to AU69657/00A priority patent/AU750912B2/en
Application filed by Iomed Inc filed Critical Iomed Inc
Priority to NZ508660A priority patent/NZ508660A/en
Priority to CN00137800.7A priority patent/CN1359665A/en
Publication of NZ508660A publication Critical patent/NZ508660A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A61N1/044—Shape of the electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A61N1/306—Arrangements where at least part of the apparatus is introduced into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)

Abstract

An iontophoretic apparatus (420) for ocular iontophoresis comprising a housing element formed (422) to cooperate with the eye. In cooperation with the housing element (422) is a flexible current distribution element (424) that is capable of transmitting electrical current. Coupled to the current distribution element is a conformable medicament containment element (426) that is filled with a medicament, which is released under the influence of an electrical current, while a barrier element (428) is provided that is configured to reduce current flow outside of the barrier and aid in the preferential delivery of medicament
NZ508660A 1999-05-25 2000-12-05 Methods and apparatus for ocular iontophoresis NZ508660A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US09/318,181 US6319240B1 (en) 1999-05-25 1999-05-25 Methods and apparatus for ocular iontophoresis
EP00123725A EP1201265A1 (en) 1999-05-25 2000-10-31 Methods and apparatus for ocular iontophoresis
CA002324779A CA2324779A1 (en) 1999-05-25 2000-10-31 Methods and apparatus for ocular iontophoresis
AU69657/00A AU750912B2 (en) 1999-05-25 2000-11-01 Methods and apparatus for ocular iontophoresis
NZ508660A NZ508660A (en) 1999-05-25 2000-12-05 Methods and apparatus for ocular iontophoresis
CN00137800.7A CN1359665A (en) 1999-05-25 2000-12-22 Eye iontophoresis and device thereof

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US09/318,181 US6319240B1 (en) 1999-05-25 1999-05-25 Methods and apparatus for ocular iontophoresis
EP00123725A EP1201265A1 (en) 1999-05-25 2000-10-31 Methods and apparatus for ocular iontophoresis
CA002324779A CA2324779A1 (en) 1999-05-25 2000-10-31 Methods and apparatus for ocular iontophoresis
AU69657/00A AU750912B2 (en) 1999-05-25 2000-11-01 Methods and apparatus for ocular iontophoresis
NZ508660A NZ508660A (en) 1999-05-25 2000-12-05 Methods and apparatus for ocular iontophoresis
CN00137800.7A CN1359665A (en) 1999-05-25 2000-12-22 Eye iontophoresis and device thereof

Publications (1)

Publication Number Publication Date
NZ508660A true NZ508660A (en) 2002-09-27

Family

ID=27542819

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ508660A NZ508660A (en) 1999-05-25 2000-12-05 Methods and apparatus for ocular iontophoresis

Country Status (6)

Country Link
US (1) US6319240B1 (en)
EP (1) EP1201265A1 (en)
CN (1) CN1359665A (en)
AU (1) AU750912B2 (en)
CA (1) CA2324779A1 (en)
NZ (1) NZ508660A (en)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL123290A (en) * 1998-02-13 2001-12-23 Hadasit Med Res Service Iontophoretic device
US6101411A (en) * 1998-09-24 2000-08-08 Newsome; David A. Dilation enhancer
US7346389B1 (en) * 1998-09-24 2008-03-18 Newsome David A Dilation enhancer with pre-medicated contact lenses
US7252655B2 (en) * 1999-05-25 2007-08-07 Iomed, Inc. Ocular iontophoretic apparatus handle
US6728573B1 (en) * 2000-02-23 2004-04-27 Iomed, Inc. Ocular iontophoretic apparatus handle
US6546283B1 (en) * 2000-10-18 2003-04-08 Iomed, Inc. High current density iontophoretic device and method of use thereof
US6579276B2 (en) * 2001-01-22 2003-06-17 Iomed, Inc. Ocular iontophoretic device and method for inhibiting vascular endothelial growth factor (VEGF) using the same
US20030023228A1 (en) * 2001-07-20 2003-01-30 Parkinson Thomas M. Ocular iontophoretic device and method for using the same
US8185209B2 (en) * 2003-01-03 2012-05-22 Board Of Trustees Operating Michigan State University Methods to extend vision to infrared wavelengths
FR2851912B1 (en) * 2003-03-03 2005-05-13 Optis France Sa UNIFORM POWER CONNECTOR FOR DELIVERY DEVICES OF ACTIVE PRINCIPLES
FR2855761B1 (en) * 2003-06-03 2006-02-24 Optis France Sa OCULAR DEVICE FOR VARIABLE DELIVERY OF ACTIVE PRINCIPLES BY IONTOPHORESIS
US7309329B2 (en) 2003-08-25 2007-12-18 Cress Jonathan H Aseptic eyedropper with collecting trough and convex release surface
US20050049562A1 (en) * 2003-08-25 2005-03-03 Cress Jonathan H. Aseptic eyedropper and method for its use
US8246949B2 (en) * 2004-10-27 2012-08-21 Aciont, Inc. Methods and devices for sustained in-vivo release of an active agent
US8262715B2 (en) * 2004-11-23 2012-09-11 Eye Delivery System, Llc Medical device and method for temperature control and treatment of the eye and surrounding tissues via magnetic drug therapy
US20070282282A1 (en) * 2004-11-23 2007-12-06 Wong Edward K Jr Medical device and method for temperature control and treatment of the eye and surrounding tissues
WO2006072887A1 (en) 2005-01-05 2006-07-13 Eyegate Pharma Sa Ocular iontophoresis device for delivering sirna and aptamers
WO2006073915A2 (en) * 2005-01-06 2006-07-13 Cyberkinetics Neurotechnology Systems, Inc. Patient training routine for biological interface system
FR2882930B1 (en) * 2005-03-09 2009-03-27 Walid Katib NOVEL OPHTHALMOLOGICAL COMPOSITIONS AND THEIR USE
US20070260171A1 (en) * 2005-09-27 2007-11-08 Higuchi John W Intraocular iontophoretic device and associated methods
US8755880B2 (en) * 2005-10-24 2014-06-17 Aciont, Inc. Intraocular iontophoretic device and associated methods
US8634907B2 (en) * 2005-10-24 2014-01-21 Aciont, Inc. Intraocular iontophoretic device and associated methods
WO2007050645A2 (en) * 2005-10-24 2007-05-03 Aciont, Inc. Intraocular iontophoretic device and associated methods
FR2893852B1 (en) * 2005-11-29 2010-09-03 Eyegate Pharma Sa OCULAR IONTOPHORESIS DEVICE
US8099162B2 (en) 2005-11-29 2012-01-17 Eyegate Pharma, S.A.S. Ocular iontophoresis device
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) * 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
WO2007131050A2 (en) * 2006-05-02 2007-11-15 Georgia Tech Research Corporation Method for drug delivery to ocular tissue using microneedle
US20080027371A1 (en) * 2006-07-26 2008-01-31 Higuchi John W Method and device for minimally invasive site specific ocular drug delivery
US8923961B2 (en) 2006-10-18 2014-12-30 The Cleveland Clinic Foundation Electrode assembly for delivering a therapeutic agent into ocular tissue
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
US8480638B2 (en) * 2007-10-04 2013-07-09 Aciont, Inc. Intraocular iontophoretic device and associated methods
US10398594B2 (en) 2007-10-04 2019-09-03 Aciont, Inc. Intrascleral drug delivery device and associated methods
US20090299267A1 (en) * 2008-05-28 2009-12-03 Isis Biopolymer Llc Iontophoretic drug delivery system with procedure window
WO2010036966A1 (en) * 2008-09-26 2010-04-01 The Cleveland Clinic Foundation Apparatus and method for delivering a therapeutic agent to ocular tissue
BRPI0924300A2 (en) * 2009-02-10 2016-01-26 Seed Co Ltd rim-shaped device and method of transferring a drug
US8409606B2 (en) 2009-02-12 2013-04-02 Incept, Llc Drug delivery through hydrogel plugs
WO2010099321A1 (en) 2009-02-26 2010-09-02 The University Of North Carolina At Chapel Hill Interventional drug delivery system and associated methods
SG175341A1 (en) * 2009-05-08 2011-11-28 Isis Biopolymer Inc Iontophoretic device with improved counterelectrode
US20110092881A1 (en) * 2009-05-08 2011-04-21 Isis Biopolymer Inc. Iontophoretic device with contact sensor
EP2485765A2 (en) * 2009-10-09 2012-08-15 Board Of Regents The University Of Texas System Photokinetic ocular drug delivery methods and apparatus
US10413506B2 (en) 2010-04-03 2019-09-17 Praful Doshi Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia
ES2634551T3 (en) 2010-04-03 2017-09-28 Praful Doshi Methods for coating a contact lens
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
WO2012051575A2 (en) 2010-10-15 2012-04-19 Iscience Interventional Corporation Device for ocular access
CA2814874C (en) 2011-01-12 2017-10-10 Sooft Italia Spa Device for corneal delivery of riboflavin by iontophoresis for the treatment of keratoconus
CA2845544A1 (en) * 2011-08-16 2013-02-21 Institut National De La Sante Et De La Recherche Medicale Device for the treatment of an ocular disease
US10226417B2 (en) 2011-09-16 2019-03-12 Peter Jarrett Drug delivery systems and applications
CA2882184C (en) 2012-08-27 2021-09-07 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using microneedles
MX2020005126A (en) 2012-11-08 2022-01-27 Clearside Biomedical Inc Methods and devices for the treatment of ocular diseases in human subjects.
US10039932B2 (en) 2012-11-20 2018-08-07 Biolase, Inc. Eyelid treatment device
KR102282973B1 (en) 2013-05-03 2021-07-27 클리어사이드 바이오메디컬, 인코포레이드 Apparatus and methods for ocular injection
US10188550B2 (en) 2013-06-03 2019-01-29 Clearside Biomedical, Inc. Apparatus and methods for drug delivery using multiple reservoirs
JP2017524419A (en) 2014-06-20 2017-08-31 クリアサイド バイオメディカル，インコーポレイテッド Variable diameter cannula and method for controlling insertion depth for drug delivery
USD750223S1 (en) 2014-10-14 2016-02-23 Clearside Biomedical, Inc. Medical injector for ocular injection
JP2018502639A (en) 2015-01-22 2018-02-01 アイゲート ファーマスーティカルズ，インコーポレイテッド Iontophoresis contact lens
WO2017139375A1 (en) 2016-02-10 2017-08-17 Clearside Biomedical, Inc. Ocular injection kit, packaging, and methods of use
EP3452165A1 (en) 2016-05-02 2019-03-13 Clearside Biomedical, Inc. Systems and methods for ocular drug delivery
WO2018031913A1 (en) 2016-08-12 2018-02-15 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
EP3599987A4 (en) 2017-03-23 2020-12-16 Doheny Eye Institute SYSTEMS, METHODS AND DEVICES FOR OPTICAL COHERENCE TOMOGRAPHY WITH MULTI-ENFACE ANGIOGRAPHY MEANS
US12090294B2 (en) * 2017-05-02 2024-09-17 Georgia Tech Research Corporation Targeted drug delivery methods using a microneedle
CA3126275A1 (en) 2019-01-09 2020-07-16 Twenty Twenty Therapeutics Llc Programmable therapeutic agent delivery from eye mounted device
KR102650504B1 (en) * 2019-01-09 2024-03-22 트웬티 트웬티 테라퓨틱스 엘엘씨 Eye-mounted device for therapeutic agent release
CN113413541A (en) * 2021-06-17 2021-09-21 中央民族大学 Eye iontophoresis drug delivery device and method using annular electrode

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US542508A (en) * 1895-07-09 Andrew p
US2525381A (en) * 1947-09-25 1950-10-10 Tower Paul Contact-type electrode holder
US3122137A (en) * 1961-10-30 1964-02-25 Erlanger Gustav Device for facilitating iontophoresis treatment of eyes
SU939019A1 (en) * 1980-07-18 1982-06-30 Львовский Научно-Исследовательский Институт Туберкулеза Device for electrophoresis of medicinal preparations
US4416274A (en) 1981-02-23 1983-11-22 Motion Control, Inc. Ion mobility limiting iontophoretic bioelectrode
US4564016A (en) * 1982-05-24 1986-01-14 The Board Of Trustees Of The Leland Stanford Junior University Apparatus for introducing ionized drugs into the posterior segment of the eye and method
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
US5053000A (en) * 1985-11-13 1991-10-01 Imperial Chemical Industries Plc Ocular treatment
US4955378A (en) * 1988-05-02 1990-09-11 University Of South Florida Apparatus and methods for performing electrofusion at specific anatomical sites
US5248295A (en) * 1989-05-08 1993-09-28 Iomed, Inc. Bioelectrode seal
US5374241A (en) 1989-07-21 1994-12-20 Iomed, Inc. Electrodes for iontophoresis
US5174304A (en) * 1990-02-16 1992-12-29 Latina Mark A Electrocycloablation apparatus and method
US5160316A (en) 1990-09-10 1992-11-03 Henley Julian L Iontophoretic drug delivery apparatus
US5169384A (en) * 1991-08-16 1992-12-08 Bosniak Stephen L Apparatus for facilitating post-traumatic, post-surgical, and/or post-inflammatory healing of tissue
WO1998014236A1 (en) * 1996-09-30 1998-04-09 Becton Dickinson And Company Designs to prevent transport of drug solution for use in assembly or packaging of an iontophoretic patch
FR2773320B1 (en) * 1998-01-05 2000-03-03 Optisinvest DEVICE FOR INTRAOCULAR TRANSFER OF ACTIVE PRODUCTS BY IONTOPHORESIS
IL123290A (en) 1998-02-13 2001-12-23 Hadasit Med Res Service Iontophoretic device
AU8820198A (en) * 1998-08-19 2000-03-14 Gal-Ion Blaze Ltd. Method and device for topical administration of substances
US6101411A (en) * 1998-09-24 2000-08-08 Newsome; David A. Dilation enhancer

Also Published As

Publication number Publication date
CN1359665A (en) 2002-07-24
CA2324779A1 (en) 2002-04-30
AU6965700A (en) 2002-05-02
US6319240B1 (en) 2001-11-20
EP1201265A1 (en) 2002-05-02
AU750912B2 (en) 2002-08-01

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