[go: up one dir, main page]

NZ337958A - Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption - Google Patents

Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption

Info

Publication number
NZ337958A
NZ337958A NZ337958A NZ33795898A NZ337958A NZ 337958 A NZ337958 A NZ 337958A NZ 337958 A NZ337958 A NZ 337958A NZ 33795898 A NZ33795898 A NZ 33795898A NZ 337958 A NZ337958 A NZ 337958A
Authority
NZ
New Zealand
Prior art keywords
digestive enzymes
motilin
zsig33
recruitment
secretion
Prior art date
Application number
NZ337958A
Other languages
English (en)
Inventor
Paul O Sheppard
Theresa A Deisher
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/822,897 external-priority patent/US6380158B1/en
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of NZ337958A publication Critical patent/NZ337958A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
NZ337958A 1997-03-24 1998-03-23 Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption NZ337958A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4110297P 1997-03-24 1997-03-24
US08/822,897 US6380158B1 (en) 1997-03-24 1997-03-24 Motilin homologs
PCT/US1998/005620 WO1998042840A1 (en) 1997-03-24 1998-03-23 Motilin homologs

Publications (1)

Publication Number Publication Date
NZ337958A true NZ337958A (en) 2001-03-30

Family

ID=26717805

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ337958A NZ337958A (en) 1997-03-24 1998-03-23 Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption

Country Status (9)

Country Link
JP (1) JP4335318B2 (no)
KR (1) KR20010005701A (no)
CN (1) CN1170933C (no)
AU (1) AU726423B2 (no)
BR (1) BR9808059A (no)
CA (1) CA2284733C (no)
NO (1) NO994614L (no)
NZ (1) NZ337958A (no)
WO (1) WO1998042840A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627729B1 (en) 1997-03-24 2003-09-30 Zymogenetics, Inc. TML peptides
US6420521B1 (en) 1999-06-30 2002-07-16 Zymogenetics, Inc. Short gastrointestinal peptides
JP2003503055A (ja) * 1999-06-30 2003-01-28 ザイモジェネティクス，インコーポレイティド Ｓｇｉｐペプチド
CN101693736B (zh) 1999-07-23 2020-09-11 寒川贤治 新的肽
WO2001038355A2 (en) 1999-11-22 2001-05-31 Zymogenetics, Inc. Method of forming a peptide-receptor complex with zsig33 and therapeutic use thereof
WO2001087933A2 (en) * 2000-05-11 2001-11-22 Zymogenetics, Inc. Zsig33-like peptides
US6897286B2 (en) 2000-05-11 2005-05-24 Zymogenetics, Inc. Zsig33-like peptides
JP2004514651A (ja) 2000-05-30 2004-05-20 メルク　エンド　カムパニー　インコーポレーテッド グレリン類似体
JP4928261B2 (ja) 2003-06-18 2012-05-09 トランザイム・ファーマ・インコーポレイテッド モチリン受容体の大環状拮抗薬
WO2008033328A2 (en) 2006-09-11 2008-03-20 Tranzyme Pharma, Inc. Macrocyclic antagonists of the motilin receptor for treatment of gastrointestinal dysmotility disorders
WO2011013728A1 (ja) * 2009-07-29 2011-02-03 第一三共株式会社 経粘膜吸収性を付与したモチリン類似ペプチド化合物
JP7049775B2 (ja) 2017-04-03 2022-04-07 リンナイ株式会社 表示装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611832D0 (en) 1986-05-15 1986-06-25 Holland I B Polypeptide
US5006469A (en) * 1988-02-09 1991-04-09 Oregon Health Sciences University Vectors and host cells expressing prepromotilin and motilin-associated peptide (MAP)
US5037743A (en) 1988-08-05 1991-08-06 Zymogenetics, Inc. BAR1 secretion signal
JPH04299990A (ja) * 1991-03-27 1992-10-23 Sanwa Kagaku Kenkyusho Co Ltd モチリンアナログの精製方法

Also Published As

Publication number Publication date
JP4335318B2 (ja) 2009-09-30
KR20010005701A (ko) 2001-01-15
CN1170933C (zh) 2004-10-13
WO1998042840A1 (en) 1998-10-01
CN1254375A (zh) 2000-05-24
JP2001513651A (ja) 2001-09-04
NO994614D0 (no) 1999-09-23
NO994614L (no) 1999-11-23
CA2284733C (en) 2010-10-26
AU726423B2 (en) 2000-11-09
BR9808059A (pt) 2000-03-08
CA2284733A1 (en) 1998-10-01
AU6576998A (en) 1998-10-20

Similar Documents

Publication Publication Date Title
NZ337958A (en) Motilin homolog designated zsig33 for treating gastrointestinal cell contractility, secretion of digestive enzymes, gastrointestinal motility, recruitment of digestive enzymes, reflux disease and regulation of nutrient absorption
KR0148009B1 (ko) 인터루킨-1 억제제
Wiegand et al. Rat guanylin cDNA: characterization of the precursor of an endogenous activator of intestinal guanylate cyclase
SG108208A1 (en) Connective tissue growth factor
EP1005540A4 (en) IKK-BETA PROTEINS, NUCLEIC ACIDS AND METHODS
EP0731106A1 (en) Novel peptide derivative
FI109206B (fi) Interleukiini-1 inhibiittoreita koodittavat DNA-sekvenssit, niitä sisältävät vektorit ja isäntäsolut sekä menetelmä interleukiini-1-inhibiittoreiden valmistamiseksi
EP1270745A3 (en) Thymosin B15 as a marker in diagnosis and prognosis of cancer
CA2327266A1 (en) Pesticidal toxins and nucleotide sequences which encode these toxins
CA2343569A1 (en) Mammalian transforming growth factor beta - 9
EP1077218A3 (en) Peptido-mimetic compounds containing RGD sequence useful as integrin inhibitors
Takeda et al. Cloning, expression and characterization of horse L-ferritin in Escherichia coli
AU3230797A (en) Dna encoding dp. 75 and a process for its use
JP2002517193A5 (no)
Egelseer et al. Characterization of an S-layer glycoprotein produced in the course of S-layer variation of Bacillus stearothermophilu s ATCC 12980 and sequencing and cloning of the sbsD gene encoding the protein moiety
GB9526178D0 (en) Novel polynuceotides and polypeptides in pathogenic mycobacteria and their use as diagnostics,vaccines and targets for chemotherapy
CA2432971A1 (en) Polypeptides
ATE287952T1 (de) Humanes thymosin beta 15 gen,protein und dessen verwendungen
EP1556084A2 (en) Methods of regulating body weight
WO2003033710A1 (fr) Nouvelle n-acetylglucosamine transferase, acide nucleique codant cette enzyme, anticorps dirige contre cette enzyme et utilisation de l'enzyme pour diagnostiquer un cancer ou une tumeur
JP2001515720A (ja) β−デフェンシン
CA2241786A1 (en) Novel amp activated protein kinase
KR960034416A (ko) 아폽토시스 조절 유전자
PT1095143E (pt) Inibidor para o diagnóstico e tratamento de doentes com hemofilia a
WO1998008866B1 (en) Bau, a bin1 interacting protein, and uses therefor

Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
EXPY Patent expired