NZ333023A - Treatment of ischemia referfusion injury and treatment of cellular dysfunction including arrhythmia and heart failure subsequent to myocardial infarction using pyridoxal-5'-phosphate, pyridoxine, pyridoxal and pyridoxamine - Google Patents
Treatment of ischemia referfusion injury and treatment of cellular dysfunction including arrhythmia and heart failure subsequent to myocardial infarction using pyridoxal-5'-phosphate, pyridoxine, pyridoxal and pyridoxamineInfo
- Publication number
- NZ333023A NZ333023A NZ33302398A NZ33302398A NZ333023A NZ 333023 A NZ333023 A NZ 333023A NZ 33302398 A NZ33302398 A NZ 33302398A NZ 33302398 A NZ33302398 A NZ 33302398A NZ 333023 A NZ333023 A NZ 333023A
- Authority
- NZ
- New Zealand
- Prior art keywords
- pyridoxal
- treatment
- pyridoxamine
- pyridoxine
- ischemia
- Prior art date
Links
- RADKZDMFGJYCBB-UHFFFAOYSA-N Pyridoxal Chemical compound CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 title abstract 4
- NHZMQXZHNVQTQA-UHFFFAOYSA-N pyridoxamine Chemical compound CC1=NC=C(CO)C(CN)=C1O NHZMQXZHNVQTQA-UHFFFAOYSA-N 0.000 title abstract 4
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 title abstract 4
- 206010019280 Heart failures Diseases 0.000 title abstract 2
- 208000027418 Wounds and injury Diseases 0.000 title abstract 2
- 230000006793 arrhythmia Effects 0.000 title abstract 2
- 206010003119 arrhythmia Diseases 0.000 title abstract 2
- 230000001413 cellular effect Effects 0.000 title abstract 2
- 230000006378 damage Effects 0.000 title abstract 2
- 230000004064 dysfunction Effects 0.000 title abstract 2
- 208000014674 injury Diseases 0.000 title abstract 2
- 208000028867 ischemia Diseases 0.000 title abstract 2
- 208000010125 myocardial infarction Diseases 0.000 title abstract 2
- 235000008164 pyridoxal Nutrition 0.000 title abstract 2
- 239000011674 pyridoxal Substances 0.000 title abstract 2
- 229960003581 pyridoxal Drugs 0.000 title abstract 2
- NGVDGCNFYWLIFO-UHFFFAOYSA-N pyridoxal 5'-phosphate Chemical compound CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O NGVDGCNFYWLIFO-UHFFFAOYSA-N 0.000 title abstract 2
- 235000007682 pyridoxal 5'-phosphate Nutrition 0.000 title abstract 2
- 239000011589 pyridoxal 5'-phosphate Substances 0.000 title abstract 2
- 235000008151 pyridoxamine Nutrition 0.000 title abstract 2
- 239000011699 pyridoxamine Substances 0.000 title abstract 2
- 235000008160 pyridoxine Nutrition 0.000 title abstract 2
- 239000011677 pyridoxine Substances 0.000 title abstract 2
- 229940011671 vitamin b6 Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Use of pyridoxal-5'-phosphate, pyridoxine, pyridoxal and pyridoxamine in the manufacture of a medicament for the treatment of ischemia referfusion injury and cellular dysfunction including arrhythmia and heart failure subsequent to myocardial infarction
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11227798A | 1998-07-09 | 1998-07-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
NZ333023A true NZ333023A (en) | 2000-08-25 |
Family
ID=22343046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NZ33302398A NZ333023A (en) | 1998-07-09 | 1998-11-26 | Treatment of ischemia referfusion injury and treatment of cellular dysfunction including arrhythmia and heart failure subsequent to myocardial infarction using pyridoxal-5'-phosphate, pyridoxine, pyridoxal and pyridoxamine |
Country Status (4)
Country | Link |
---|---|
JP (1) | JP2000026295A (en) |
AU (2) | AU759824B2 (en) |
CA (1) | CA2254528C (en) |
NZ (1) | NZ333023A (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1531157B1 (en) * | 2000-02-29 | 2008-03-19 | Medicure International Inc. | Cardioprotective phosphonates |
US7442689B2 (en) | 2000-02-29 | 2008-10-28 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
WO2001064692A1 (en) | 2000-02-29 | 2001-09-07 | Medicure International Inc. | Cardioprotective phosphonates and malonates |
US6897228B2 (en) | 2000-07-07 | 2005-05-24 | Medicure International Inc. | Pyridoxine and pyridoxal analogues: new uses |
US7459468B2 (en) | 2004-10-28 | 2008-12-02 | Medicure International, Inc. | Aryl sulfonic pyridoxines as antiplatelet agents |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ222664A (en) * | 1986-11-29 | 1990-06-26 | Vesta Med Pty Ltd | Pharmaceutical compositions containing pyridoxal as a source of vitamin b6 |
JPH09221425A (en) * | 1996-02-13 | 1997-08-26 | Taiho Yakuhin Kogyo Kk | Thiol protease inhibitor |
-
1998
- 1998-11-26 NZ NZ33302398A patent/NZ333023A/en unknown
- 1998-11-26 CA CA 2254528 patent/CA2254528C/en not_active Expired - Fee Related
- 1998-11-27 JP JP10338077A patent/JP2000026295A/en active Pending
- 1998-11-27 AU AU94210/98A patent/AU759824B2/en not_active Revoked
-
2007
- 2007-06-06 AU AU2007202621A patent/AU2007202621A1/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU2007202621A1 (en) | 2007-06-28 |
AU9421098A (en) | 2000-02-03 |
CA2254528A1 (en) | 2000-01-09 |
CA2254528C (en) | 2007-07-17 |
JP2000026295A (en) | 2000-01-25 |
AU759824B2 (en) | 2003-05-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RENW | Renewal (renewal fees accepted) | ||
RENW | Renewal (renewal fees accepted) | ||
ASS | Change of ownership |
Owner name: MEDICURE INC., CA Free format text: OLD OWNER(S): UNIVERSITY OF MANITOBA Owner name: THE UNIVERSITY OF MANITOBA, CA Free format text: OLD OWNER(S): UNIVERSITY OF MANITOBA |
|
RENW | Renewal (renewal fees accepted) |