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NZ239250A - Chirally pure non-nucleotide reagents for use in preparing - Google Patents

Chirally pure non-nucleotide reagents for use in preparing

Info

Publication number
NZ239250A
NZ239250A NZ239250A NZ23925091A NZ239250A NZ 239250 A NZ239250 A NZ 239250A NZ 239250 A NZ239250 A NZ 239250A NZ 23925091 A NZ23925091 A NZ 23925091A NZ 239250 A NZ239250 A NZ 239250A
Authority
NZ
New Zealand
Prior art keywords
preparing
chirally pure
pure non
nucleotide reagents
nucleotide
Prior art date
Application number
NZ239250A
Inventor
Mark A Reynolds
Morteza M Vaghefi
Lyle J Arnold
Original Assignee
Genta Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genta Inc filed Critical Genta Inc
Publication of NZ239250A publication Critical patent/NZ239250A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/26Amides of acids of phosphorus containing P-halide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18Fluorenes; Hydrogenated fluorenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NZ239250A 1990-08-09 1991-08-02 Chirally pure non-nucleotide reagents for use in preparing NZ239250A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56530790A 1990-08-09 1990-08-09

Publications (1)

Publication Number Publication Date
NZ239250A true NZ239250A (en) 1993-12-23

Family

ID=24258038

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ239250A NZ239250A (en) 1990-08-09 1991-08-02 Chirally pure non-nucleotide reagents for use in preparing

Country Status (9)

Country Link
EP (1) EP0542928A4 (en)
JP (1) JPH05507419A (en)
KR (1) KR930701468A (en)
AU (1) AU664542B2 (en)
CA (1) CA2089087A1 (en)
IE (1) IE912805A1 (en)
IL (1) IL99068A (en)
NZ (1) NZ239250A (en)
WO (1) WO1992002532A1 (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ239252A (en) * 1990-08-09 1997-07-27 Genta Inc Reagent for attaching a psoralen-containing moiety to an oligonucleotide(derivative); oligonucleotide(derivative)-psoralen conjugates
DE4239531A1 (en) * 1992-11-25 1994-05-26 Gabor Dr Igloi Reagent for coupling various substances to nucleic acids and process for its production
AU7019794A (en) * 1993-05-26 1994-12-20 Genta Incorporated Oligomer conjugates and their use
WO1995014030A1 (en) * 1993-11-16 1995-05-26 Genta Incorporated Synthetic oligomers having chirally pure phosphonate internucleosidyl linkages mixed with non-phosphonate internucleosidyl linkages
JPH09505307A (en) * 1993-11-16 1997-05-27 ジンタ・インコーポレイテッド Multi-chiral synthetic phosphonate oligomers
CA2176498A1 (en) * 1993-11-16 1995-05-26 Lyle John Arnold, Jr. Synthetic oligomers having phosphonate internucleosidyl linkages of undefined chirality mixed with non-phosphonate internucleosidyl linkages
US5955597A (en) * 1993-11-16 1999-09-21 Genta, Incorporated Chirally enriched synthetic phosphate oligomers
US6448373B1 (en) 1994-01-11 2002-09-10 Isis Pharmaceuticals, Inc. Phosphate linked oligomers formed of monomeric diols and processes for preparing same
US6184389B1 (en) 1994-01-11 2001-02-06 Isis Pharmaceuticals, Inc. Combinatorial libraries having aminodiol monomer subunits
US5886177A (en) * 1994-01-11 1999-03-23 Isis Pharmaceuticals, Inc. Phosphate linked oligomers
US6828427B1 (en) 1994-01-11 2004-12-07 Isis Pharmaceuticals, Inc. Oligomeric aminodiol-containing compounds, libraries thereof, and process of preparing the same
US5854410A (en) * 1994-03-31 1998-12-29 Genta Incorporated Oligonucleoside cleavage compounds and therapies
IT1270694B (en) * 1994-11-15 1997-05-07 Italfarmaco Spa FLUORENYL-HYDROXAMIC DERIVATIVES FOR IMMUNOSOPPRESSIVE AND ANTI-INFLAMMATORY ACTIVITIES
US5919965A (en) * 1995-01-18 1999-07-06 Genzyme Corporation Non-nucleotide phosphorus ester oligomers
US6211354B1 (en) * 1998-05-06 2001-04-03 Tosch Corporation Optically active DNA probe having phosphonic diester linkage
EP2544688B1 (en) 2010-03-02 2016-09-07 President and Fellows of Harvard College Methods and compositions for treatment of angelman syndrome
AU2012271413B2 (en) 2011-06-17 2017-07-13 President And Fellows Of Harvard College Frizzled 2 as a target for therapeutic antibodies in the treatment of cancer
EP2724156B1 (en) 2011-06-27 2017-08-16 The Jackson Laboratory Methods and compositions for treatment of cancer and autoimmune disease
US20140178877A1 (en) * 2012-12-20 2014-06-26 Roche Molecular Systems, Inc. Labeled Oligonucleotide Probes Used for Nucleic Acid Sequence Analysis
WO2014157565A1 (en) * 2013-03-28 2014-10-02 国立大学法人北陸先端科学技術大学院大学 Photoresponsive nucleotide analogue having photocrosslinking ability
EP3660022A4 (en) 2017-07-26 2021-04-21 Japan Advanced Institute of Science and Technology ANALOGUE OF PHOTOSENSITIVE NUCLEOTIDE CAPABLE OF PHOTORETICULATION IN A REGION OF VISIBLE LIGHT
JP6920689B2 (en) 2017-07-26 2021-08-18 日華化学株式会社 Photoreactive nucleotide analogs that can be photocrosslinked in the visible light region

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3440190A (en) * 1965-09-08 1969-04-22 Du Pont Oligonucleotide compositions and the process for the preparation thereof
FR2565996B1 (en) * 1984-06-15 1988-01-22 Inst Nat Sante Rech Med CHEMICALLY MARKED NUCLEIC ACIDS, THEIR USE AND THE NECESSARY FOR ITS IMPLEMENTATION
US4757141A (en) * 1985-08-26 1988-07-12 Applied Biosystems, Incorporated Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof
JP3012244B2 (en) * 1987-09-21 2000-02-21 ジェン―プローブ インコーポレイテッド Non-nucleotide ligation reagent for nucleotide probes
FR2642074B1 (en) * 1989-01-20 1994-04-29 Oris Ind POLYHYDROXYLATED MOLECULE DERIVATIVES FOR THE INTRODUCTION OF AT LEAST ONE BRANCH INTO AN OLIGONUCLEOTIDE

Also Published As

Publication number Publication date
WO1992002532A1 (en) 1992-02-20
EP0542928A1 (en) 1993-05-26
AU664542B2 (en) 1995-11-23
KR930701468A (en) 1993-06-11
IE912805A1 (en) 1992-02-12
IL99068A (en) 1998-01-04
CA2089087A1 (en) 1992-02-10
EP0542928A4 (en) 1994-07-27
IL99068A0 (en) 1992-07-15
JPH05507419A (en) 1993-10-28
AU9071091A (en) 1992-03-02

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