[go: up one dir, main page]

NZ212937A - Omega interferons: production by recombinant dna processes; pharmaceutical compositions - Google Patents

Omega interferons: production by recombinant dna processes; pharmaceutical compositions

Info

Publication number
NZ212937A
NZ212937A NZ212937A NZ21293785A NZ212937A NZ 212937 A NZ212937 A NZ 212937A NZ 212937 A NZ212937 A NZ 212937A NZ 21293785 A NZ21293785 A NZ 21293785A NZ 212937 A NZ212937 A NZ 212937A
Authority
NZ
New Zealand
Prior art keywords
production
pharmaceutical compositions
recombinant dna
dna processes
interferons
Prior art date
Application number
NZ212937A
Inventor
Rudolf Hauptmann
Peter Meindl
Eva Rastl-Dworkin
Gunther Adolf
Peter Swetly
Christian Pieler
Norbert Hauel
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE3428370A external-priority patent/DE3428370A1/en
Priority claimed from DE19853505060 external-priority patent/DE3505060A1/en
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of NZ212937A publication Critical patent/NZ212937A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Electrotherapy Devices (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The type I interferon peptides encoded by the genetic DNA sequences are called omega-interferons and are produced using appropriate expression vehicles and organisms.
NZ212937A 1984-08-01 1985-07-31 Omega interferons: production by recombinant dna processes; pharmaceutical compositions NZ212937A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3428370A DE3428370A1 (en) 1984-08-01 1984-08-01 Interferon, genetic sequences which code therefor, and organisms producing these
DE19853505060 DE3505060A1 (en) 1985-02-14 1985-02-14 Type I interferons, genetic sequences which code therefor, and organisms producing these

Publications (1)

Publication Number Publication Date
NZ212937A true NZ212937A (en) 1991-08-27

Family

ID=25823496

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ212937A NZ212937A (en) 1984-08-01 1985-07-31 Omega interferons: production by recombinant dna processes; pharmaceutical compositions

Country Status (21)

Country Link
EP (1) EP0170204B1 (en)
JP (2) JP2566909B2 (en)
KR (1) KR0136799B1 (en)
AT (1) ATE67786T1 (en)
AU (1) AU600653B2 (en)
BG (1) BG60445B2 (en)
CA (1) CA1340184C (en)
DD (1) DD246318A5 (en)
DE (1) DE3584198D1 (en)
DK (1) DK175194B1 (en)
ES (2) ES8609475A1 (en)
FI (1) FI90667C (en)
GR (1) GR851866B (en)
HK (1) HK187896A (en)
HU (1) HU205779B (en)
IE (1) IE58942B1 (en)
IL (1) IL75963A (en)
MX (1) MX9203645A (en)
NO (1) NO177863C (en)
NZ (1) NZ212937A (en)
PT (1) PT80901B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5231176A (en) * 1984-08-27 1993-07-27 Genentech, Inc. Distinct family DNA encoding of human leukocyte interferons
DE3607835A1 (en) * 1986-03-10 1987-09-24 Boehringer Ingelheim Int HYBRID INTERFERONS, THEIR USE AS MEDICINAL PRODUCTS AND AS INTERMEDIATE PRODUCTS FOR THE PRODUCTION OF ANTIBODIES AND THE USE THEREOF AND METHOD FOR THEIR PRODUCTION
EP0490233A1 (en) * 1986-03-10 1992-06-17 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Monoclonal antibodies against Bgl III-hybrid interferons, their use and process for preparing them
US4863727A (en) * 1986-04-09 1989-09-05 Cetus Corporation Combination therapy using interleukin-2 and tumor necrosis factor
DE3633323A1 (en) * 1986-10-01 1988-04-07 Boehringer Ingelheim Int NEW MONOCLONAL ANTIBODIES AGAINST IFN-OMEGA, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE FOR CLEANING AND DETECTING IFN-OMEGA
DE3635867A1 (en) * 1986-10-22 1988-05-11 Boehringer Ingelheim Int NEW YEAR EXPRESSION VECTORS FOR IFN-OMEGA, METHOD FOR THEIR PRODUCTION AND USE THEREOF
WO1999026663A2 (en) * 1997-11-20 1999-06-03 Vical, Inc. Treatment of cancer using cytokine-expressing polynucleotides and compositions therefor
WO2000040273A2 (en) * 1999-01-08 2000-07-13 Vical Incorporated Treatment of viral diseases using an interferon omega expressing polynucleotide
AU2003205502C1 (en) 2002-03-07 2011-08-25 Eidgenossische Technische Hochschule Zurich System and method for the production of recombinant glycosylated proteins in a prokaryotic host
KR100938026B1 (en) * 2002-03-07 2010-01-21 아이드게노쉬쉐 테흐니쉐 호흐슐레 쥬리히 Production method and production system of recombinant glycosylated protein in prokaryotic host
EP2055189A1 (en) 2003-04-09 2009-05-06 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
WO2004096852A1 (en) * 2003-04-25 2004-11-11 The Institute Of Microbiology And Epidemiology, Academy Of Military Medical Sciemces, Pla A RECOMBINANT HUMAN INTERFERON ϖ, THE METHOD FOR EXPRESSING IT AND THE USES OF IT
ES2703061T3 (en) 2005-05-11 2019-03-06 Eth Zuerich N-glycosylated recombinant proteins from prokaryotic cells
EP3427749A1 (en) 2008-02-20 2019-01-16 GlaxoSmithKline Biologicals SA Bioconjugates made from recombinant n-glycosylated proteins from procaryotic cells
TR201803015T4 (en) 2009-11-19 2018-03-21 Glaxosmithkline Biologicals Sa Biosynthetic system producing immunogenic polysaccharides in prokaryotic cells.
CN103079591B (en) 2010-05-06 2017-07-28 格林考瓦因有限公司 Capsular gram-positive bacteria bioconjugate vaccine
WO2013024156A2 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of anti-hcv-entry factor antibodies and interferons for the treatment and the prevention of hcv infection
WO2013024158A1 (en) 2011-08-17 2013-02-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Combinations of protein kinase inhibitors and interferons or of protein kinase inhibitors and direct acting antivirals for the treatment and the prevention of hcv infection
WO2014033266A1 (en) 2012-08-31 2014-03-06 INSERM (Institut National de la Santé et de la Recherche Médicale) Anti-sr-bi antibodies for the inhibition of hepatitis c virus infection

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1946283A (en) * 1982-08-18 1984-03-07 Cetus Corporation Interferon-alpha 6l
CA1217440A (en) * 1982-08-18 1987-02-03 Michael A. Innis INTERFERON .alpha. 6L
DE3247922A1 (en) * 1982-12-24 1984-06-28 Boehringer Ingelheim International GmbH, 6507 Ingelheim DNA SEQUENCES, THEIR PRODUCTION, PLASMIDES CONTAINING THESE SEQUENCES AND THE USE THEREOF FOR THE SYNTHESIS OF EUKARYOTIC GENE PRODUCTS IN PROKARYOTS
ATE47864T1 (en) * 1984-08-27 1989-11-15 Genentech Inc MISCELLANEOUS FAMILY OF HUMAN WBC INTERFERONS, COMPOSITIONS CONTAINING THEM, METHODS FOR THEIR PRODUCTION, AND DNA AND TRANSFECTED HOSTS THEREOF.

Also Published As

Publication number Publication date
IL75963A0 (en) 1985-12-31
HUT39477A (en) 1986-09-29
JP2567195B2 (en) 1996-12-25
EP0170204A2 (en) 1986-02-05
ATE67786T1 (en) 1991-10-15
IE851906L (en) 1986-02-01
DD246318A5 (en) 1987-06-03
ES8708013A1 (en) 1987-09-01
JP2566909B2 (en) 1996-12-25
FI852956A0 (en) 1985-07-31
PT80901B (en) 1989-01-17
NO177863C (en) 1995-12-06
BG60445B2 (en) 1995-03-31
JPS61181381A (en) 1986-08-14
EP0170204A3 (en) 1988-02-17
JPH06181771A (en) 1994-07-05
KR870001310A (en) 1987-03-13
ES545725A0 (en) 1986-08-01
DE3584198D1 (en) 1991-10-31
DK175194B1 (en) 2004-07-05
FI852956L (en) 1986-02-02
IL75963A (en) 1992-05-25
AU600653B2 (en) 1990-08-23
AU4554985A (en) 1986-02-06
DK346385D0 (en) 1985-07-30
HU205779B (en) 1992-06-29
ES8609475A1 (en) 1986-08-01
DK346385A (en) 1986-02-02
NO177863B (en) 1995-08-28
HK187896A (en) 1996-10-18
CA1340184C (en) 1998-12-15
EP0170204B1 (en) 1991-09-25
NO853012L (en) 1986-02-03
PT80901A (en) 1985-09-01
GR851866B (en) 1985-12-02
FI90667B (en) 1993-11-30
MX9203645A (en) 1992-09-01
ES552431A0 (en) 1987-09-01
KR0136799B1 (en) 1998-04-25
FI90667C (en) 1994-03-10
IE58942B1 (en) 1993-12-01

Similar Documents

Publication Publication Date Title
NZ212937A (en) Omega interferons: production by recombinant dna processes; pharmaceutical compositions
IL64243A (en) Hybrid human leukocyte interferon type anti-viral polypeptides,their preparation by genetic engineering methods and pharmaceutical compositions containing them
ES8308534A1 (en) DNA sequences, recombinant DNA molecules and processes for producing human interferon-alpha like polypeptides.
ES8403969A1 (en) DNA sequences, recombinant DNA molecules and processes for producing human immune interferon-like polypeptides.
IL77369A (en) Alpha, beta or omega horse interferon, their preparation and pharmaceutical compositions containing them, recombinant dna coding therefor and transformed host organisms containing such dna
ES8504936A1 (en) Deoxyribonucleic acids, recombinant deoxyribonucleic acids, hosts containing them, polypeptides and process for their production.
HUT46061A (en) Dna sequences encoding hirudin-like protein and process for producing such proteins
IT8119760A0 (en) POLYPEPTIDE PRODUCED MICROBIOLOGICALLY WITH THE AMINO ACIDS SEQUENCE OF HUMAN INTERFERON, DNA AND PLASMIDS THAT CODE FOR THIS SEQUENCE, MICROORGANISMS THAT CONTAIN THIS GENETIC INFORMATION AND PROCESS FOR THEIR PREPARATION.
DK1396542T3 (en) P-selectin ligand protein
IL70856A0 (en) Dna sequences,recombinant dna molecules and processes for producing human interleukin two-like polypeptides
EP0088622A3 (en) Animal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and expression vehicles containing such sequences and cells transformed thereby
IL80562A0 (en) Recombinant human lysozyme,its preparation by recombinant dna technology and pharmaceutical compositions containing it
DE3850774D1 (en) BEEF INTERLEUKIN 1 ALPHA.
EP0183272A3 (en) Vector capable of efficient gene expression and utilization of such vector
SG134394G (en) Genetic sequences, type I interferon peptide coded by them, and these organisms producing the same
ZA84512B (en) Dna sequences,recombinant dna molecules and processes for producing human interleukin two-like polypeptides
ZA812189B (en) Dna sequences, recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides
HK19189A (en) Dna sequences,recombinant dna molecules and processes for producing human interferon-alpha like polypeptides