[go: up one dir, main page]

NO994901D0 - Treatment of central nervous disorders by selective estrogen receptor modulators - Google Patents

Treatment of central nervous disorders by selective estrogen receptor modulators

Info

Publication number
NO994901D0
NO994901D0 NO994901A NO994901A NO994901D0 NO 994901 D0 NO994901 D0 NO 994901D0 NO 994901 A NO994901 A NO 994901A NO 994901 A NO994901 A NO 994901A NO 994901 D0 NO994901 D0 NO 994901D0
Authority
NO
Norway
Prior art keywords
treatment
central nervous
estrogen receptor
receptor modulators
selective estrogen
Prior art date
Application number
NO994901A
Other languages
Norwegian (no)
Other versions
NO994901L (en
Inventor
Kelly Renee Bales
Henry Uhlman Bryant
Steven Marc Paul
Mary Patricia Knadler
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO994901D0 publication Critical patent/NO994901D0/en
Publication of NO994901L publication Critical patent/NO994901L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO994901A 1997-04-09 1999-10-08 Treatment of central nervous disorders by selective estrogen receptor modulators NO994901L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4311797P 1997-04-09 1997-04-09
PCT/US1998/007024 WO1998045287A1 (en) 1997-04-09 1998-04-07 Treatment of central nervous system disorders with selective estrogen receptor modulators

Publications (2)

Publication Number Publication Date
NO994901D0 true NO994901D0 (en) 1999-10-08
NO994901L NO994901L (en) 1999-12-09

Family

ID=21925589

Family Applications (1)

Application Number Title Priority Date Filing Date
NO994901A NO994901L (en) 1997-04-09 1999-10-08 Treatment of central nervous disorders by selective estrogen receptor modulators

Country Status (19)

Country Link
US (2) US6077852A (en)
EP (1) EP0986556A4 (en)
JP (1) JP2001518898A (en)
KR (1) KR20010006219A (en)
CN (1) CN1260792A (en)
AU (1) AU733421B2 (en)
BR (1) BR9809389A (en)
CA (1) CA2286455A1 (en)
EA (1) EA002360B1 (en)
HU (1) HUP0002031A3 (en)
ID (1) ID27986A (en)
IL (1) IL132278A0 (en)
NO (1) NO994901L (en)
NZ (2) NZ500175A (en)
PL (1) PL336701A1 (en)
TR (1) TR199902700T2 (en)
TW (1) TW479056B (en)
WO (1) WO1998045287A1 (en)
ZA (1) ZA982877B (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6096781A (en) * 1997-11-14 2000-08-01 Eli Lilly And Company 2-arylbenzo[B]thiophenes useful for the treatment of estrogen deprivation syndrome
US6288108B1 (en) 1998-06-16 2001-09-11 Eli Lilly And Company Methods for increasing levels of acetylcholine
KR20010052891A (en) 1998-06-16 2001-06-25 피터 지. 스트링거 Methods for Increasing Levels of Acetylcholine
TR200003714T2 (en) * 1998-06-16 2001-07-23 Eli Lilly And Company Raising the level of acetylcholine
US6087378A (en) * 1998-10-13 2000-07-11 Eli Lilly And Company Pharmaceutical formulations and applications thereof for the treatment of estrogen deprivation syndrome
US6610706B1 (en) 1999-07-29 2003-08-26 Eli Lilly And Company Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene hydrochloride
WO2001009115A2 (en) * 1999-07-29 2001-02-08 Eli Lilly And Company A NOVEL CRYSTALLINE FORM OF 6-HYDROXY-3- (4-[2-(PIPERIDIN-1- YL)ETHOXY] PHENOXY)-2- (4-METHOXYPHENYL) BENZO[b]THIOPHENE HYDROCHLORIDE
US6653479B1 (en) 1999-07-29 2003-11-25 Eli Lilly And Company Crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b] thiophene hydrochloride
AU6335600A (en) * 1999-07-29 2001-02-19 Eli Lilly And Company A novel crystalline form of 6-hydroxy-3-(4-[2-(piperidin-1-yl)ethoxy]phenoxy)-2-(4-metho yphenyl)benzo[b]thiophene hydrochloride
EP1757291A3 (en) * 2000-05-08 2009-07-15 Eli Lilly & Company Stabilized formulations of 6-hydroxy-3-(4-[2-(piperidin-1-YL)ethoxy]phenoxy)-2-(4-methoxyphenyl)benzo[b]thiophene and salts thereof
JP2003535827A (en) * 2000-05-08 2003-12-02 イーライ・リリー・アンド・カンパニー Stabilized formulation of 6-hydroxy-3- (4- [2- (piperidin-1-yl) ethoxy] phenoxy) -2- (4-methoxyphenyl) benzo [b] thiophene and its salts
EA005116B1 (en) * 2000-10-20 2004-10-28 Эли Лилли Энд Компани A NOVEL CRYSTALLINE FORM OF 6-HUDROXY-3-(4-[2-PIPERIDIN-1-YL)ETHOXY]PHENOXY)-2-(4-METHOXYPHENYL)BENZO[b]THIOPHENE HYDROCHLORIDE
BRPI0808740A2 (en) * 2007-03-16 2014-08-12 Lilly Co Eli ARZOXYPHEN PREPARATION PROCESS AND INTERMEDIARIES.
EA022760B1 (en) 2007-10-16 2016-02-29 Репрос Терапьютикс Инк. Use of trans-clomiphene for prevention or treatment of type 2 diabetes in men
DE102010027016A1 (en) 2010-07-09 2012-01-12 Universitätsklinikum Jena New steroid-styryl dye conjugates useful e.g. for simulation and direct light optical detection of the behavior of steroid in the living biological tissue in the presence of a steroid binding protein
AU2013225869B2 (en) 2012-02-29 2017-06-08 Repros Therapeutics Inc. Combination therapy for treating androgen deficiency
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
MA38325B1 (en) 2013-02-19 2019-03-29 Novartis Ag Benzothiophene derivatives and compositions thereof as selective estrogen receptor degradation agents
GB201311891D0 (en) 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compound
GB201311888D0 (en) * 2013-07-03 2013-08-14 Glaxosmithkline Ip Dev Ltd Novel compounds
CN104829569B (en) * 2015-05-12 2017-04-26 广州中医药大学 Application of 2-phenyl-benzo-five-membered heterocycle compound and derivative of 2-phenyl-benzo-five-membered heterocycle compound
CN104829568B (en) * 2015-05-12 2017-03-01 广州中医药大学 A kind of 2 phenyl benzene a pair of horses going side by side five-membered heterocycles and its medical applications of derivant
JP7048505B2 (en) 2015-11-10 2022-04-05 パラクリン セラピューティクス エービー Treatment of ER-negative breast cancer with PDGF-CC inhibitors and antiestrogens
ES2975558T3 (en) 2016-09-15 2024-07-09 Arvinas Inc Indole derivatives as estrogen receptor degraders
IL266842B (en) 2016-12-01 2022-09-01 Arvinas Operations Inc History of tetrahydronaphthalene and tetrahydroisoquinoline as estrogen receptor antagonists
KR20230140606A (en) 2017-01-26 2023-10-06 아비나스 오퍼레이션스, 인코포레이티드 Modulators of estrogen receptor proteolysis and associated methods of use
JP2021534177A (en) * 2018-08-16 2021-12-09 ジー１ セラピューティクス， インコーポレイテッド Benzothiophene estrogen receptor modulator for treating medical disorders
CN118986983A (en) 2019-08-26 2024-11-22 阿尔维纳斯运营股份有限公司 Method for treating breast cancer using tetrahydronaphthalene derivatives as estrogen receptor degrading agents
BR112023004656A2 (en) 2020-09-14 2023-05-09 Arvinas Operations Inc CRYSTALLINE AND AMORPHOUS FORMS OF A COMPOUND FOR THE TARGETED DEGRADATION OF THE ESTROGEN RECEPTOR

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862232A (en) * 1963-07-03 1975-01-21 Upjohn Co 1-(p-hydroxyphenyl)-2-phenyl-6-(2-diethylaminoethoxy)-3,4-dihydronaphthalene and the salts thereof
US3293263A (en) * 1963-12-09 1966-12-20 Upjohn Co Diphenylbenzocycloalkenes
US3320271A (en) * 1964-06-01 1967-05-16 Upjohn Co 1, 2-diphenyl-3, 4-dihydronaphthalenes and 2, 3-diphenylindenes
GB1138163A (en) * 1965-05-21 1968-12-27 Bristol Myers Co Benzothiophene derivatives having anti-fertility properties
US3394125A (en) * 1965-10-23 1968-07-23 Bristol Myers Co 2-phenyl-3-tertiary-aminoalkoxy phenyl-and corresponding tertiaryaminoalkyl thio benzfurans substituted in the benzo nucleus with an alkoxy or tertiaryamino alkoxy or alkylthio group
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4230862A (en) * 1975-10-28 1980-10-28 Eli Lilly And Company Antifertility compounds
US4117128A (en) * 1976-08-03 1978-09-26 Smithkline Corporation Sulfonyl benzofurans and benzothiophenes having coronary vasodilator activity
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
GB8311678D0 (en) * 1983-04-28 1983-06-02 Ici Plc Phenol derivatives
GB8705174D0 (en) * 1987-03-05 1987-04-08 Ici Plc Heterocyclic compounds
US5013761A (en) * 1988-06-03 1991-05-07 Eli Lilly And Company Serotonin antagonists
FR2665444B1 (en) * 1990-08-06 1992-11-27 Sanofi Sa AMINO-BENZOFURAN, BENZOTHIOPHENE OR INDOLE DERIVATIVES, THEIR PREPARATION PROCESS AND THE COMPOSITIONS CONTAINING THEM.
US5254568A (en) * 1990-08-09 1993-10-19 Council Of Scientific & Industrial Research Benzopyrans as antiestrogenic agents
DE4117512A1 (en) * 1991-05-25 1992-11-26 Schering Ag 2-PHENYLBENZO (B) FURANES AND THIOPHENES, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
JP3157882B2 (en) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 New benzothiophene derivatives
US6756388B1 (en) * 1993-10-12 2004-06-29 Pfizer Inc. Benzothiophenes and related compounds as estrogen agonists
US6489355B2 (en) * 1993-12-01 2002-12-03 Eli Lilly And Company Methods of inhibiting the effects of amyloidogenic proteins
US5578613A (en) * 1993-12-21 1996-11-26 Eli Lilly And Company Methods for inhibiting weight gain or inducing weight loss
US5534526A (en) * 1993-12-21 1996-07-09 Eli Lilly And Company Methods for inhibiting vasomotor symptoms and attending psychological disturbances surrounding post-menopausal syndrome
US5441965A (en) * 1993-12-21 1995-08-15 Eli Lilly And Company Methods of inhibiting thrombin
US5462950A (en) * 1993-12-21 1995-10-31 Eli Lilly And Company Methods of treating menstrual symptoms and compositions therefore
US5439931A (en) * 1993-12-21 1995-08-08 Eli Lilly And Company Method for increasing libido in post-menopausal women
US5552415A (en) * 1993-12-21 1996-09-03 Eli Lilly And Company Method of inhibiting Alzheimer's Disease
US5389670A (en) * 1993-12-21 1995-02-14 Eli Lilly Company Methods of inhibiting the symptoms of premenstrual syndrome/late luteal phase dysphoric disorder
US6417198B1 (en) * 1993-12-21 2002-07-09 Eli Lilly And Company Methods of inhibiting CNS problems in post-menopausal women
US5384332A (en) * 1994-05-11 1995-01-24 Eli Lilly And Company Methods for inhibiting aortal smooth muscle cell proliferation and restenosis with 1,1,2-triphenylbut-1-ene derivatives
US5512296A (en) * 1994-08-22 1996-04-30 Eli Lilly And Company Methods for inhibiting neuronal damage
US5434166A (en) * 1994-08-22 1995-07-18 Eli Lilly And Company Methods of inhibiting demyelinating and desmyelinating diseases
US6562862B1 (en) * 1994-10-20 2003-05-13 Eli Lilly And Company Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y
US5998401A (en) * 1995-02-28 1999-12-07 Eli Lilly And Company Naphthyl compounds, intermediates, compositions, and methods
US5510357A (en) * 1995-02-28 1996-04-23 Eli Lilly And Company Benzothiophene compounds as anti-estrogenic agents
JP3989569B2 (en) * 1995-02-28 2007-10-10 イーライ リリー アンド カンパニー Benzothiophene compounds, intermediates, compositions and methods
US5731342A (en) * 1996-02-22 1998-03-24 Eli Lilly And Company Benzothiophenes, formulations containing same, and methods

Also Published As

Publication number Publication date
US6077852A (en) 2000-06-20
AU7104998A (en) 1998-10-30
ZA982877B (en) 1999-10-04
WO1998045287A1 (en) 1998-10-15
KR20010006219A (en) 2001-01-26
NO994901L (en) 1999-12-09
CA2286455A1 (en) 1998-10-15
JP2001518898A (en) 2001-10-16
HUP0002031A3 (en) 2003-01-28
EA199900913A1 (en) 2000-04-24
TR199902700T2 (en) 2000-06-21
NZ500175A (en) 2001-10-26
US20020013342A1 (en) 2002-01-31
NZ514146A (en) 2001-09-28
CN1260792A (en) 2000-07-19
TW479056B (en) 2002-03-11
EP0986556A1 (en) 2000-03-22
HUP0002031A2 (en) 2001-06-28
PL336701A1 (en) 2000-07-03
EP0986556A4 (en) 2001-03-21
AU733421B2 (en) 2001-05-17
BR9809389A (en) 2002-03-19
EA002360B1 (en) 2002-04-25
ID27986A (en) 2001-05-03
IL132278A0 (en) 2001-03-19

Similar Documents

Publication Publication Date Title
NO994901D0 (en) Treatment of central nervous disorders by selective estrogen receptor modulators
NO994000D0 (en) Process of hydrogenation of hydrocarbons
NO996484D0 (en) New process for the preparation of paroxetine solid dispersion
DE69925571D1 (en) SULPHONAMIDE DERIVATIVES FOR TREATING DISORDERS OF THE CENTRAL NERVOUS SYSTEM
IL138129A0 (en) Therapy of estrogen associated disorders
PL336290A1 (en) Sulphonamides for treating endothelin-involving disorders
PL350679A1 (en) Derivatives of 1-arenosulphonyl-2-arylpyrolydine and piperidine for treating central nervous system disorders
SI0908458T1 (en) Substituted pyridylmethylpiperazine and piperidine derivatives, their preparation and their use for treating central nervous system (CNS) disorders
AU2384500A (en) Compounds, methods of screening and methods of treatment for central and peripheral nervous system disorders
HUP0201791A2 (en) The use of escitalopram for treatment of neurotic disorders
AU1686997A (en) Modified vegf antisense oligonucleotides for treatment of skin disorders
ID27214A (en) TRIAZOLOPIRIDINA FOR TREATMENT OF TROMBOSIS DISORDERS
EE200000391A (en) Triazine compounds for the treatment of central nervous system disorders
DE60019145D1 (en) USE OF CARBONYLAMINO DERIVATIVES AGAINST CENTRAL NERVOUS SYSTEM DISORDERS
ID23175A (en) THE USE OF BENZOPIRANOL TO TREAT NERVE DISORDERS
DK0935598T3 (en) 5-heteroatom-alkyl-substituted 3-oxopyrido (1,2-a) benzimidazole-4-carboxamide derivatives suitable for the treatment of central nervous system disorders
IL142589A0 (en) 3-tetrahydropyridin-4-yl indoles for treatment of psychotic disorders
NO20010390D0 (en) Treatment of anxiety disorders
NO994902D0 (en) Breast cancer prevention by selective estrogen receptor modulators
GB0010488D0 (en) Glutamate receptor modulators and the treatment of psychiatric disorders
NO20012538D0 (en) Use of N-substituted azabicycloalkane derivatives for the treatment of central nervous system disorders
UA25221A (en) METHOD OF TREATMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM
LV12285A (en) Device for Magnetotherapy of brain function disorders
ID21578A (en) SULFONAMIDE COMPOUNDS AND ITS UTILIZATION FOR TREATMENT OF NERVOUS NERVOUS DISORDERS
GB2301774B (en) Treatment of Anxiety Disorders with Piperidine Derivatives.

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application