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NO991232D0 - Substituerte benzosykloheptapyridinderivater anvendelige for inhibering av farnesylproteintransferase - Google Patents

Substituerte benzosykloheptapyridinderivater anvendelige for inhibering av farnesylproteintransferase

Info

Publication number
NO991232D0
NO991232D0 NO991232A NO991232A NO991232D0 NO 991232 D0 NO991232 D0 NO 991232D0 NO 991232 A NO991232 A NO 991232A NO 991232 A NO991232 A NO 991232A NO 991232 D0 NO991232 D0 NO 991232D0
Authority
NO
Norway
Prior art keywords
protein transferase
inhibition
farnesyl protein
derivatives useful
substituted
Prior art date
Application number
NO991232A
Other languages
English (en)
Other versions
NO991232L (no
Inventor
Arthur G Taveras
Alan K Mallams
Adriano Afonso
Ronald J Doll
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO991232D0 publication Critical patent/NO991232D0/no
Publication of NO991232L publication Critical patent/NO991232L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/59Hydrogenated pyridine rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO991232A 1996-09-13 1999-03-12 Substituerte benzosykloheptapyridinderivater anvendelige for inhibering av farnesylproteintransferase NO991232L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71292496A 1996-09-13 1996-09-13
PCT/US1997/015906 WO1998011100A1 (en) 1996-09-13 1997-09-11 Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase

Publications (2)

Publication Number Publication Date
NO991232D0 true NO991232D0 (no) 1999-03-12
NO991232L NO991232L (no) 1999-05-12

Family

ID=24864087

Family Applications (1)

Application Number Title Priority Date Filing Date
NO991232A NO991232L (no) 1996-09-13 1999-03-12 Substituerte benzosykloheptapyridinderivater anvendelige for inhibering av farnesylproteintransferase

Country Status (20)

Country Link
EP (1) EP0927179B1 (no)
JP (1) JP2001500509A (no)
KR (1) KR20000036112A (no)
CN (1) CN1109685C (no)
AT (1) ATE247106T1 (no)
AU (1) AU4337897A (no)
BR (1) BR9712825A (no)
CA (1) CA2264508C (no)
CZ (1) CZ84499A3 (no)
DE (1) DE69724130T2 (no)
ES (1) ES2205255T3 (no)
HU (1) HUP0000126A2 (no)
ID (1) ID22002A (no)
IL (1) IL128927A0 (no)
NO (1) NO991232L (no)
NZ (1) NZ334451A (no)
PL (1) PL332319A1 (no)
SK (1) SK33999A3 (no)
TR (1) TR199901189T2 (no)
WO (1) WO1998011100A1 (no)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4282233B1 (en) * 1980-06-19 2000-09-05 Schering Corp Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines
IL111235A (en) * 1993-10-15 2001-03-19 Schering Plough Corp Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
HUT76057A (en) * 1993-10-15 1997-06-30 Schering Corp Tricyclic sulfonamide compounds, pharmaceutical compositions containing them, which are useful for inhibition of g-protein function and for treatment of proliferative diseases and process for producing them

Also Published As

Publication number Publication date
IL128927A0 (en) 2000-02-17
CN1237171A (zh) 1999-12-01
CA2264508A1 (en) 1998-03-19
CZ84499A3 (cs) 1999-08-11
NO991232L (no) 1999-05-12
HUP0000126A2 (hu) 2001-04-28
DE69724130T2 (de) 2004-06-03
DE69724130D1 (de) 2003-09-18
PL332319A1 (en) 1999-08-30
NZ334451A (en) 2000-08-25
WO1998011100A1 (en) 1998-03-19
ATE247106T1 (de) 2003-08-15
JP2001500509A (ja) 2001-01-16
BR9712825A (pt) 1999-11-23
ID22002A (id) 1999-08-19
CA2264508C (en) 2003-02-18
AU4337897A (en) 1998-04-02
ES2205255T3 (es) 2004-05-01
EP0927179A1 (en) 1999-07-07
TR199901189T2 (xx) 1999-07-21
EP0927179B1 (en) 2003-08-13
KR20000036112A (ko) 2000-06-26
SK33999A3 (en) 2000-06-12
CN1109685C (zh) 2003-05-28

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NO991235D0 (no) Forbindelser anvendelige for inhibering av farnesylproteintransferase
NO991232D0 (no) Substituerte benzosykloheptapyridinderivater anvendelige for inhibering av farnesylproteintransferase
NO991231D0 (no) Forbindelser for inhibering av farnesylproteintransferase

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application