NO991232D0 - Substituerte benzosykloheptapyridinderivater anvendelige for inhibering av farnesylproteintransferase - Google Patents
Substituerte benzosykloheptapyridinderivater anvendelige for inhibering av farnesylproteintransferaseInfo
- Publication number
- NO991232D0 NO991232D0 NO991232A NO991232A NO991232D0 NO 991232 D0 NO991232 D0 NO 991232D0 NO 991232 A NO991232 A NO 991232A NO 991232 A NO991232 A NO 991232A NO 991232 D0 NO991232 D0 NO 991232D0
- Authority
- NO
- Norway
- Prior art keywords
- protein transferase
- inhibition
- farnesyl protein
- derivatives useful
- substituted
- Prior art date
Links
- 102000004357 Transferases Human genes 0.000 title abstract 2
- 108090000992 Transferases Proteins 0.000 title abstract 2
- 125000004030 farnesyl group Chemical group [H]C([*])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 title abstract 2
- XYNHQVIVVBWVAG-UHFFFAOYSA-N 4h-cyclohepta[f]quinoline Chemical class C1=CC=CC=C2C3=CC=CNC3=CC=C21 XYNHQVIVVBWVAG-UHFFFAOYSA-N 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71292496A | 1996-09-13 | 1996-09-13 | |
PCT/US1997/015906 WO1998011100A1 (en) | 1996-09-13 | 1997-09-11 | Substituted benzocycloheptapyridine derivatives useful for inhibition of farnesyl protein transferase |
Publications (2)
Publication Number | Publication Date |
---|---|
NO991232D0 true NO991232D0 (no) | 1999-03-12 |
NO991232L NO991232L (no) | 1999-05-12 |
Family
ID=24864087
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO991232A NO991232L (no) | 1996-09-13 | 1999-03-12 | Substituerte benzosykloheptapyridinderivater anvendelige for inhibering av farnesylproteintransferase |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP0927179B1 (no) |
JP (1) | JP2001500509A (no) |
KR (1) | KR20000036112A (no) |
CN (1) | CN1109685C (no) |
AT (1) | ATE247106T1 (no) |
AU (1) | AU4337897A (no) |
BR (1) | BR9712825A (no) |
CA (1) | CA2264508C (no) |
CZ (1) | CZ84499A3 (no) |
DE (1) | DE69724130T2 (no) |
ES (1) | ES2205255T3 (no) |
HU (1) | HUP0000126A2 (no) |
ID (1) | ID22002A (no) |
IL (1) | IL128927A0 (no) |
NO (1) | NO991232L (no) |
NZ (1) | NZ334451A (no) |
PL (1) | PL332319A1 (no) |
SK (1) | SK33999A3 (no) |
TR (1) | TR199901189T2 (no) |
WO (1) | WO1998011100A1 (no) |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4282233B1 (en) * | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
IL111235A (en) * | 1993-10-15 | 2001-03-19 | Schering Plough Corp | Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them |
HUT76057A (en) * | 1993-10-15 | 1997-06-30 | Schering Corp | Tricyclic sulfonamide compounds, pharmaceutical compositions containing them, which are useful for inhibition of g-protein function and for treatment of proliferative diseases and process for producing them |
-
1997
- 1997-09-11 DE DE69724130T patent/DE69724130T2/de not_active Expired - Fee Related
- 1997-09-11 PL PL97332319A patent/PL332319A1/xx unknown
- 1997-09-11 HU HU0000126A patent/HUP0000126A2/hu unknown
- 1997-09-11 CN CN97199603A patent/CN1109685C/zh not_active Expired - Fee Related
- 1997-09-11 AU AU43378/97A patent/AU4337897A/en not_active Abandoned
- 1997-09-11 CA CA002264508A patent/CA2264508C/en not_active Expired - Fee Related
- 1997-09-11 JP JP10513764A patent/JP2001500509A/ja not_active Ceased
- 1997-09-11 IL IL12892797A patent/IL128927A0/xx unknown
- 1997-09-11 EP EP97941479A patent/EP0927179B1/en not_active Expired - Lifetime
- 1997-09-11 NZ NZ334451A patent/NZ334451A/xx unknown
- 1997-09-11 ES ES97941479T patent/ES2205255T3/es not_active Expired - Lifetime
- 1997-09-11 KR KR1019997002135A patent/KR20000036112A/ko not_active Application Discontinuation
- 1997-09-11 ID IDW990088D patent/ID22002A/id unknown
- 1997-09-11 BR BR9712825-2A patent/BR9712825A/pt unknown
- 1997-09-11 SK SK339-99A patent/SK33999A3/sk unknown
- 1997-09-11 WO PCT/US1997/015906 patent/WO1998011100A1/en active IP Right Grant
- 1997-09-11 AT AT97941479T patent/ATE247106T1/de not_active IP Right Cessation
- 1997-09-11 CZ CZ99844A patent/CZ84499A3/cs unknown
- 1997-09-11 TR TR1999/01189T patent/TR199901189T2/xx unknown
-
1999
- 1999-03-12 NO NO991232A patent/NO991232L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL128927A0 (en) | 2000-02-17 |
CN1237171A (zh) | 1999-12-01 |
CA2264508A1 (en) | 1998-03-19 |
CZ84499A3 (cs) | 1999-08-11 |
NO991232L (no) | 1999-05-12 |
HUP0000126A2 (hu) | 2001-04-28 |
DE69724130T2 (de) | 2004-06-03 |
DE69724130D1 (de) | 2003-09-18 |
PL332319A1 (en) | 1999-08-30 |
NZ334451A (en) | 2000-08-25 |
WO1998011100A1 (en) | 1998-03-19 |
ATE247106T1 (de) | 2003-08-15 |
JP2001500509A (ja) | 2001-01-16 |
BR9712825A (pt) | 1999-11-23 |
ID22002A (id) | 1999-08-19 |
CA2264508C (en) | 2003-02-18 |
AU4337897A (en) | 1998-04-02 |
ES2205255T3 (es) | 2004-05-01 |
EP0927179A1 (en) | 1999-07-07 |
TR199901189T2 (xx) | 1999-07-21 |
EP0927179B1 (en) | 2003-08-13 |
KR20000036112A (ko) | 2000-06-26 |
SK33999A3 (en) | 2000-06-12 |
CN1109685C (zh) | 2003-05-28 |
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NO991229D0 (no) | Substituerte benzosykloheptapyridinderivater for inhibering av farnesylproteintransferase | |
NO991235D0 (no) | Forbindelser anvendelige for inhibering av farnesylproteintransferase | |
NO991232D0 (no) | Substituerte benzosykloheptapyridinderivater anvendelige for inhibering av farnesylproteintransferase | |
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Legal Events
Date | Code | Title | Description |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |