NO984144L - Composition comprising heparin as a non-thrombogenic surface coating - Google Patents
Composition comprising heparin as a non-thrombogenic surface coatingInfo
- Publication number
- NO984144L NO984144L NO984144A NO984144A NO984144L NO 984144 L NO984144 L NO 984144L NO 984144 A NO984144 A NO 984144A NO 984144 A NO984144 A NO 984144A NO 984144 L NO984144 L NO 984144L
- Authority
- NO
- Norway
- Prior art keywords
- composition
- heparin
- surface coating
- thrombogenic surface
- thrombogenic
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002897 heparin Drugs 0.000 title abstract 2
- 229920000669 heparin Polymers 0.000 title abstract 2
- 230000001453 nonthrombogenic effect Effects 0.000 title abstract 2
- 239000011248 coating agent Substances 0.000 title 1
- 238000000576 coating method Methods 0.000 title 1
- 230000008321 arterial blood flow Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
- A61L33/0029—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate using an intermediate layer of polymer
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0078—Degradation products
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Paints Or Removers (AREA)
Abstract
The present invention relates to a composition comprising heparin to be used as a non-thrombogenic surface when in contact with arterial blood flow. It also relates to a device treated on the surface thereof with such a composition.
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO984144A NO984144L (en) | 1998-09-09 | 1998-09-09 | Composition comprising heparin as a non-thrombogenic surface coating |
DK99944937T DK1112098T3 (en) | 1998-09-09 | 1999-09-09 | Use of a composition containing heparin as a non-thrombogenic surface coating agent to prevent arterial thrombosis. |
AT99944937T ATE232113T1 (en) | 1998-09-09 | 1999-09-09 | USE OF A COMPOSITION CONTAINING HEPARIN AS A NON-THROMBogenic SURFACE COATING AGENT FOR THE PROPHYLAXIS OF ARTERY THROBOSIS |
CA2342992A CA2342992C (en) | 1998-09-09 | 1999-09-09 | Non-thrombotic surface coatings comprising high affinity heparin |
AU57653/99A AU762201B2 (en) | 1998-09-09 | 1999-09-09 | Composition comprising heparin as a non-thrombogenic surface coating agent |
EP99944937A EP1112098B1 (en) | 1998-09-09 | 1999-09-09 | Use of a composition comprising heparin as a non-thrombogenic surface coating agent for preventing arterial thrombosis |
KR1020017002937A KR100603224B1 (en) | 1998-09-09 | 1999-09-09 | Compositions comprising heparin as non-thrombotic surface coating |
US09/763,856 US6559132B1 (en) | 1998-09-09 | 1999-09-09 | Composition comprising heparin as a non-thrombogenic surface coating agent |
BR9913517-5A BR9913517A (en) | 1998-09-09 | 1999-09-09 | Composition, device, and, use of a composition |
DE69905258T DE69905258T2 (en) | 1998-09-09 | 1999-09-09 | USE OF A COMPOSITION WITH HEPARIN AS A NON-THROMBOW SURFACE COATING AGENT FOR PROPHYLAXIS OF ARTERIENTHROBOSIS |
PCT/NO1999/000278 WO2000013719A1 (en) | 1998-09-09 | 1999-09-09 | Composition comprising heparin as a non-thrombogenic surface coating agent |
ES99944937T ES2192860T3 (en) | 1998-09-09 | 1999-09-09 | USE OF A COMPOSITION THAT INCLUDES HEPARINE AS A NON-THROMBOGENIC SURFACE COATING AGENT TO PREVENT ARTERIAL THROMBOSIS. |
JP2000568524A JP4489297B2 (en) | 1998-09-09 | 1999-09-09 | Methods of using compositions containing heparin |
NO20011181A NO321372B1 (en) | 1998-09-09 | 2001-03-08 | Use of a composition comprising heparin for the preparation of a non-thrombogenic surface. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NO984144A NO984144L (en) | 1998-09-09 | 1998-09-09 | Composition comprising heparin as a non-thrombogenic surface coating |
Publications (2)
Publication Number | Publication Date |
---|---|
NO984144D0 NO984144D0 (en) | 1998-09-09 |
NO984144L true NO984144L (en) | 2000-03-10 |
Family
ID=19902394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO984144A NO984144L (en) | 1998-09-09 | 1998-09-09 | Composition comprising heparin as a non-thrombogenic surface coating |
Country Status (13)
Country | Link |
---|---|
US (1) | US6559132B1 (en) |
EP (1) | EP1112098B1 (en) |
JP (1) | JP4489297B2 (en) |
KR (1) | KR100603224B1 (en) |
AT (1) | ATE232113T1 (en) |
AU (1) | AU762201B2 (en) |
BR (1) | BR9913517A (en) |
CA (1) | CA2342992C (en) |
DE (1) | DE69905258T2 (en) |
DK (1) | DK1112098T3 (en) |
ES (1) | ES2192860T3 (en) |
NO (1) | NO984144L (en) |
WO (1) | WO2000013719A1 (en) |
Families Citing this family (63)
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US6641610B2 (en) | 1998-09-10 | 2003-11-04 | Percardia, Inc. | Valve designs for left ventricular conduits |
US6254564B1 (en) | 1998-09-10 | 2001-07-03 | Percardia, Inc. | Left ventricular conduit with blood vessel graft |
EP1669042A3 (en) * | 1998-09-10 | 2006-06-28 | Percardia, Inc. | TMR shunt |
US6290728B1 (en) | 1998-09-10 | 2001-09-18 | Percardia, Inc. | Designs for left ventricular conduit |
WO2000015147A1 (en) * | 1998-09-10 | 2000-03-23 | Percardia, Inc. | Transmycardial shunt and its attachment mechanism, for left ventricular revascularization |
US6409697B2 (en) | 1999-05-04 | 2002-06-25 | Heartstent Corporation | Transmyocardial implant with forward flow bias |
US7033372B1 (en) | 1999-08-04 | 2006-04-25 | Percardia, Inc. | Corkscrew reinforced left ventricle to coronary artery channel |
US6638237B1 (en) | 1999-08-04 | 2003-10-28 | Percardia, Inc. | Left ventricular conduits and methods for delivery |
JP3782297B2 (en) * | 2000-03-28 | 2006-06-07 | 株式会社東芝 | Solid-state imaging device and manufacturing method thereof |
US6854467B2 (en) * | 2000-05-04 | 2005-02-15 | Percardia, Inc. | Methods and devices for delivering a ventricular stent |
US20020032478A1 (en) * | 2000-08-07 | 2002-03-14 | Percardia, Inc. | Myocardial stents and related methods of providing direct blood flow from a heart chamber to a coronary vessel |
US6976990B2 (en) | 2001-01-25 | 2005-12-20 | Percardia, Inc. | Intravascular ventriculocoronary bypass via a septal passageway |
US6783525B2 (en) | 2001-12-12 | 2004-08-31 | Megadyne Medical Products, Inc. | Application and utilization of a water-soluble polymer on a surface |
US6949118B2 (en) | 2002-01-16 | 2005-09-27 | Percardia, Inc. | Encased implant and methods |
US7008397B2 (en) | 2002-02-13 | 2006-03-07 | Percardia, Inc. | Cardiac implant and methods |
US6685704B2 (en) | 2002-02-26 | 2004-02-03 | Megadyne Medical Products, Inc. | Utilization of an active catalyst in a surface coating of an electrosurgical instrument |
US6619357B1 (en) | 2002-04-24 | 2003-09-16 | The Goodyear Tire & Rubber Company | Belt package for super single truck tires |
US6951559B1 (en) | 2002-06-21 | 2005-10-04 | Megadyne Medical Products, Inc. | Utilization of a hybrid material in a surface coating of an electrosurgical instrument |
US7326219B2 (en) * | 2002-09-09 | 2008-02-05 | Wilk Patent Development | Device for placing transmyocardial implant |
US6702850B1 (en) | 2002-09-30 | 2004-03-09 | Mediplex Corporation Korea | Multi-coated drug-eluting stent for antithrombosis and antirestenosis |
FR2846520B1 (en) * | 2002-11-06 | 2006-09-29 | Roquette Freres | USE OF MALTODEXTRINS BRANCHED AS BLEACHES OF GRANULATION |
US7198751B2 (en) * | 2003-01-14 | 2007-04-03 | Medtronic, Inc. | Disposable, integrated, extracorporeal blood circuit |
US7201870B2 (en) * | 2003-01-14 | 2007-04-10 | Medtronic, Inc. | Active air removal system operating modes of an extracorporeal blood circuit |
US7204958B2 (en) * | 2003-01-14 | 2007-04-17 | Medtronic, Inc. | Extracorporeal blood circuit air removal system and method |
US7189352B2 (en) * | 2003-01-14 | 2007-03-13 | Medtronic, Inc. | Extracorporeal blood circuit priming system and method |
US7335334B2 (en) * | 2003-01-14 | 2008-02-26 | Medtronic, Inc. | Active air removal from an extracorporeal blood circuit |
CA2559741A1 (en) * | 2004-03-26 | 2005-10-20 | Surmodics, Inc. | A medical article having a bioactive agent-releasing component with photoreactive groups |
EP2329852A1 (en) * | 2004-03-26 | 2011-06-08 | SurModics, Inc. | Composition and method for preparing biocompatible surfaces |
US20050281857A1 (en) * | 2004-05-25 | 2005-12-22 | Heyer Toni M | Methods and reagents for preparing biomolecule-containing coatings |
US20060154894A1 (en) * | 2004-09-15 | 2006-07-13 | Massachusetts Institute Of Technology | Biologically active surfaces and methods of their use |
US20060159650A1 (en) * | 2005-01-14 | 2006-07-20 | Bacterin, Inc. | Composition and method for covalently coupling an antithrombotic substance and a hydrophilic polymer |
DE102005003632A1 (en) | 2005-01-20 | 2006-08-17 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Catheter for the transvascular implantation of heart valve prostheses |
US20090281059A1 (en) * | 2007-02-21 | 2009-11-12 | Robert Falotico | Coating for a medical device having an anti-thrombotic conjugate |
US20080200421A1 (en) * | 2007-02-21 | 2008-08-21 | Zhao Jonathon Z | Coating for a medical device having an anti-thrombotic conjugate |
US9693841B2 (en) | 2007-04-02 | 2017-07-04 | Ension, Inc. | Surface treated staples, sutures and dental floss and methods of manufacturing the same |
WO2008122034A1 (en) | 2007-04-02 | 2008-10-09 | Ension, Inc. | Process for preparing a substrate coated with a biomolecule |
US7896915B2 (en) | 2007-04-13 | 2011-03-01 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US8383156B2 (en) | 2007-04-30 | 2013-02-26 | Cordis Corporation | Coating for a medical device having an anti-thrombotic conjugate |
US20090018646A1 (en) | 2007-07-10 | 2009-01-15 | Zhao Jonathon Z | Coating Employing an Anti-Thrombotic Conjugate |
US20090036841A1 (en) * | 2007-08-01 | 2009-02-05 | Mckale James M | Coatings for blood and bone marrow-contacting devices |
US20090192079A1 (en) * | 2007-10-09 | 2009-07-30 | Genzyme Corporation | Prolonged delivery of heparin-binding growth factors from heparin-derivatized collagen |
WO2011104269A1 (en) | 2008-02-26 | 2011-09-01 | Jenavalve Technology Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US9044318B2 (en) | 2008-02-26 | 2015-06-02 | Jenavalve Technology Gmbh | Stent for the positioning and anchoring of a valvular prosthesis |
GB0816783D0 (en) | 2008-09-15 | 2008-10-22 | Carmeda Ab | Immobilised biological entities |
US8829071B2 (en) * | 2009-02-21 | 2014-09-09 | Sofradim Production | Medical device with degradation-retarding coating |
AU2010215936B2 (en) | 2009-02-21 | 2015-03-05 | Covidien Lp | Medical devices having activated surfaces |
US20110196478A1 (en) * | 2010-02-10 | 2011-08-11 | Beoptima Inc. | Devices and methods for lumen treatment |
US9744031B2 (en) | 2010-05-25 | 2017-08-29 | Jenavalve Technology, Inc. | Prosthetic heart valve and endoprosthesis comprising a prosthetic heart valve and a stent |
US9180274B2 (en) | 2010-09-09 | 2015-11-10 | W. L. G ore & Associates, Inc | Indwelling luminal devices |
IT1402059B1 (en) * | 2010-09-29 | 2013-08-28 | Rand Srl | WEARABLE SYSTEM TO CARRY OUT PURIFYING THERAPIES OF ORGANIC FLUIDS WITH THE USE OF EXTRACORPY CIRCUITS |
US9775933B2 (en) | 2012-03-02 | 2017-10-03 | W. L. Gore & Associates, Inc. | Biocompatible surfaces and devices incorporating such surfaces |
CN105073148B (en) | 2013-04-12 | 2017-08-04 | 东丽株式会社 | Artificial blood vessel with antithrombotic |
WO2015028209A1 (en) | 2013-08-30 | 2015-03-05 | Jenavalve Technology Gmbh | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
EP3270825B1 (en) | 2015-03-20 | 2020-04-22 | JenaValve Technology, Inc. | Heart valve prosthesis delivery system |
WO2016177562A1 (en) | 2015-05-01 | 2016-11-10 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
EP3095509A1 (en) | 2015-05-18 | 2016-11-23 | Defymed | Membranes functionalized with heparin for bioartificial organs |
EP3454795B1 (en) | 2016-05-13 | 2023-01-11 | JenaValve Technology, Inc. | Heart valve prosthesis delivery system for delivery of heart valve prosthesis with introducer sheath and loading system |
EP3318294A1 (en) | 2016-11-08 | 2018-05-09 | Defymed | Kit for in situ delivery of a compound of interest |
US11197754B2 (en) | 2017-01-27 | 2021-12-14 | Jenavalve Technology, Inc. | Heart valve mimicry |
KR20200037574A (en) | 2018-10-01 | 2020-04-09 | (주)우리비앤비 | Cosmetic composition for preventing hair loss comprising heparin |
EP3892259A1 (en) | 2020-04-09 | 2021-10-13 | Defymed | Membranes for medical devices |
JP2023521400A (en) | 2020-04-09 | 2023-05-24 | デファイメッド | Membrane for medical devices |
WO2024102411A1 (en) | 2022-11-09 | 2024-05-16 | Jenavalve Technology, Inc. | Catheter system for sequential deployment of an expandable implant |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4446126A (en) * | 1980-09-30 | 1984-05-01 | Cutter Laboratories, Inc. | Antithrombin-heparin complex and method for its production |
SE456347B (en) | 1982-02-09 | 1988-09-26 | Ird Biomaterial Ab | SURFACE MODIFIED SOLID SUBSTRATE AND PROCEDURES FOR PRODUCING THEREOF |
US6174326B1 (en) | 1996-09-25 | 2001-01-16 | Terumo Kabushiki Kaisha | Radiopaque, antithrombogenic stent and method for its production |
-
1998
- 1998-09-09 NO NO984144A patent/NO984144L/en not_active Application Discontinuation
-
1999
- 1999-09-09 JP JP2000568524A patent/JP4489297B2/en not_active Expired - Lifetime
- 1999-09-09 AU AU57653/99A patent/AU762201B2/en not_active Expired
- 1999-09-09 EP EP99944937A patent/EP1112098B1/en not_active Expired - Lifetime
- 1999-09-09 BR BR9913517-5A patent/BR9913517A/en not_active Application Discontinuation
- 1999-09-09 WO PCT/NO1999/000278 patent/WO2000013719A1/en active IP Right Grant
- 1999-09-09 DK DK99944937T patent/DK1112098T3/en active
- 1999-09-09 CA CA2342992A patent/CA2342992C/en not_active Expired - Lifetime
- 1999-09-09 AT AT99944937T patent/ATE232113T1/en active
- 1999-09-09 ES ES99944937T patent/ES2192860T3/en not_active Expired - Lifetime
- 1999-09-09 US US09/763,856 patent/US6559132B1/en not_active Expired - Lifetime
- 1999-09-09 DE DE69905258T patent/DE69905258T2/en not_active Expired - Lifetime
- 1999-09-09 KR KR1020017002937A patent/KR100603224B1/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1112098A1 (en) | 2001-07-04 |
DE69905258T2 (en) | 2003-11-06 |
ES2192860T3 (en) | 2003-10-16 |
NO984144D0 (en) | 1998-09-09 |
JP2002524153A (en) | 2002-08-06 |
EP1112098B1 (en) | 2003-02-05 |
AU762201B2 (en) | 2003-06-19 |
JP4489297B2 (en) | 2010-06-23 |
KR20010079758A (en) | 2001-08-22 |
DE69905258D1 (en) | 2003-03-13 |
AU5765399A (en) | 2000-03-27 |
WO2000013719A1 (en) | 2000-03-16 |
CA2342992C (en) | 2010-11-23 |
KR100603224B1 (en) | 2006-07-24 |
US6559132B1 (en) | 2003-05-06 |
DK1112098T3 (en) | 2003-05-05 |
CA2342992A1 (en) | 2000-03-16 |
BR9913517A (en) | 2001-06-05 |
ATE232113T1 (en) | 2003-02-15 |
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Legal Events
Date | Code | Title | Description |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |