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NO981320L - Oral use of (+) - O-demethyltramadol as a pain reliever - Google Patents

Oral use of (+) - O-demethyltramadol as a pain reliever

Info

Publication number
NO981320L
NO981320L NO981320A NO981320A NO981320L NO 981320 L NO981320 L NO 981320L NO 981320 A NO981320 A NO 981320A NO 981320 A NO981320 A NO 981320A NO 981320 L NO981320 L NO 981320L
Authority
NO
Norway
Prior art keywords
demethyltramadol
oral use
pain reliever
pain
reliever
Prior art date
Application number
NO981320A
Other languages
Norwegian (no)
Other versions
NO981320D0 (en
Inventor
Elmar Josef Friderichs
Werner Winter
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of NO981320D0 publication Critical patent/NO981320D0/en
Publication of NO981320L publication Critical patent/NO981320L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Det er beskrevet anvendelse av (+)-0-demetyltramadol for oral tilførsel ved behandlingen av sterke, akutte og/eller kroniske smerter.The use of (+) - 0-demethyltramadol for oral administration has been described in the treatment of severe, acute and / or chronic pain.

NO981320A 1997-03-25 1998-03-24 Oral use of (+) - O-demethyltramadol as a pain reliever NO981320L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19712398A DE19712398A1 (en) 1997-03-25 1997-03-25 Oral use of (+) - 0-demethyltramadol as a pain reliever

Publications (2)

Publication Number Publication Date
NO981320D0 NO981320D0 (en) 1998-03-24
NO981320L true NO981320L (en) 1998-09-28

Family

ID=7824498

Family Applications (1)

Application Number Title Priority Date Filing Date
NO981320A NO981320L (en) 1997-03-25 1998-03-24 Oral use of (+) - O-demethyltramadol as a pain reliever

Country Status (14)

Country Link
EP (1) EP0870499A1 (en)
JP (1) JPH1112166A (en)
KR (1) KR19980080580A (en)
CN (1) CN1196932A (en)
AU (1) AU5951798A (en)
BR (1) BR9801839A (en)
CA (1) CA2232930A1 (en)
DE (1) DE19712398A1 (en)
HU (1) HUP9800623A3 (en)
IL (1) IL123788A0 (en)
NO (1) NO981320L (en)
PE (1) PE62399A1 (en)
PL (1) PL325509A1 (en)
UY (1) UY24934A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20010623A1 (en) * 1999-10-05 2001-07-07 Gruenenthal Chemie USE OF (+) - TRAMADOL AND / OR O-DEMETILTRAMADOL FOR TREATMENT OF INCREASED URINARY URGENCY AND / OR URINARY INCONTINENCE
DE10108123A1 (en) * 2001-02-21 2002-10-02 Gruenenthal Gmbh drug combination
WO2011110595A1 (en) 2010-03-10 2011-09-15 Grünenthal GmbH Crystalline salts and/or cocrystals of o-desmethyltramadol
US10702485B2 (en) * 2011-07-09 2020-07-07 Syntrix Biosystems Inc. Compositions and methods for overcoming resistance to tramadol

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69215316T2 (en) * 1991-09-06 1997-03-20 Mcneilab Inc Compositions containing tramadol and any codeine, oxycode or hydrocode and their use
AU661723B2 (en) * 1991-10-30 1995-08-03 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
DE4315525B4 (en) * 1993-05-10 2010-04-15 Euro-Celtique S.A. Pharmaceutical composition
DE4329794C2 (en) * 1993-09-03 1997-09-18 Gruenenthal Gmbh Tramadol salt-containing drugs with delayed release
DE19525137C2 (en) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexane compounds as intermediates for the preparation of pharmaceutical agents
DE19601744C2 (en) * 1996-01-19 1998-04-16 Gruenenthal Gmbh Process for the preparation of the enantiomers of O-demethyltramadol

Also Published As

Publication number Publication date
DE19712398A1 (en) 1998-10-01
HU9800623D0 (en) 1998-05-28
JPH1112166A (en) 1999-01-19
HUP9800623A3 (en) 1999-03-29
AU5951798A (en) 1998-10-01
IL123788A0 (en) 1998-10-30
PL325509A1 (en) 1998-09-28
BR9801839A (en) 2000-01-18
CN1196932A (en) 1998-10-28
PE62399A1 (en) 1999-07-10
EP0870499A1 (en) 1998-10-14
CA2232930A1 (en) 1998-09-25
NO981320D0 (en) 1998-03-24
UY24934A1 (en) 1998-04-21
KR19980080580A (en) 1998-11-25
HUP9800623A2 (en) 1999-01-28

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