NO981054D0 - Sykliske nitroner og farmasöytiske preparater inneholdende disse - Google Patents

Sykliske nitroner og farmasöytiske preparater inneholdende disse

Info

Publication number: NO981054D0
Authority: NO; Norway
Prior art keywords: pharmaceutical preparations; preparations containing; nitrons; cyclic; cyclic nitrons
Prior art date: 1995-09-11

Application number

NO981054A

Other languages

English (en)

Other versions

NO311357B1 (no

NO981054L (no

Inventor

Craig Eugene Thomas

Thomas Lee Fevig

Stephen Marc Bowen

Robert Allan Farr

Albert Anthony Carr

David Alan Janowick

Original Assignee

Hoechst Marion Roussel Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-11

Filing date

1998-03-10

Publication date

1998-03-10

1998-03-10 Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc

1998-03-10 Publication of NO981054L publication Critical patent/NO981054L/no

1998-03-10 Publication of NO981054D0 publication Critical patent/NO981054D0/no

2001-11-19 Publication of NO311357B1 publication Critical patent/NO311357B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/08—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Biochemistry (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO19981054A 1995-09-11 1998-03-10 Sykliske nitroner og farmasöytiske preparater inneholdende disse NO311357B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US355195P	1995-09-11	1995-09-11
PCT/US1996/013312 WO1997010218A1 (en)	1995-09-11	1996-08-15	Cyclic nitrones and pharmaceutical compositions containing them

Publications (3)

Publication Number	Publication Date
NO981054L NO981054L (no)	1998-03-10
NO981054D0 true NO981054D0 (no)	1998-03-10
NO311357B1 NO311357B1 (no)	2001-11-19

Family

ID=21706397

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19981054A NO311357B1 (no)	1995-09-11	1998-03-10	Sykliske nitroner og farmasöytiske preparater inneholdende disse

Country Status (21)

Country	Link
US (1)	US5962469A (no)
EP (1)	EP0863878B1 (no)
JP (1)	JPH11512427A (no)
KR (1)	KR100512675B1 (no)
CN (3)	CN1500779A (no)
AR (1)	AR004950A1 (no)
AT (2)	ATE293604T1 (no)
AU (1)	AU701989B2 (no)
CA (1)	CA2231812C (no)
DE (2)	DE69634647T2 (no)
DK (2)	DK1288203T3 (no)
ES (2)	ES2185797T3 (no)
HU (1)	HUP9803028A3 (no)
IL (1)	IL123345A (no)
MX (1)	MX9801892A (no)
NO (1)	NO311357B1 (no)
NZ (1)	NZ316288A (no)
PT (2)	PT1288203E (no)
TW (1)	TW337520B (no)
WO (1)	WO1997010218A1 (no)
ZA (1)	ZA967514B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69904018D1 (en) *	1998-01-16	2003-01-02	Centaur Pharmaceuticals Inc	Thiophennitronderivate
WO2000043397A1 (en) *	1999-01-19	2000-07-27	Neurosearch A/S	Fused heterocyclic compounds and their use in the treatment of neurodegenerative diseases
CN100513395C (zh) *	2006-04-17	2009-07-15	中国科学院化学研究所	一种制备多羟基环状硝酮的方法
CN101565453B (zh) *	2008-04-22	2011-12-21	中国科学院化学研究所	具有捕获自由基功能的硝酮类化合物及其制备方法与应用
ES2395803B1 (es) *	2011-08-01	2013-12-19	Consejo Superior De Investigaciones Científicas (Csic) - 80%	Quinolilnitronas
US8883857B2 (en)	2012-12-07	2014-11-11	Baylor College Of Medicine	Small molecule xanthine oxidase inhibitors and methods of use
US10660851B2 (en)	2015-01-02	2020-05-26	Rxos Medical	Polyfunctional radical scavenger hydrogel formulation
CN105985389B (zh) *	2015-03-06	2019-03-19	北京大学	苯乙醇苷类似物及其合成方法和应用
JP7033081B2 (ja)	2016-02-08	2022-03-09	ルナフォア・テクノロジーズ・エスアー	試料サイクル多重化及びインサイツイメージングの方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US35112A (en) *		1862-04-29		Improvement in head-rests for car-seats
US3044930A (en) *	1960-12-08	1962-07-17	Phillips Petroleum Co	N-oxides of heterocyclic nitrogen compounds as bird and rodent repellents
US3796715A (en) *	1967-08-30	1974-03-12	Hoffmann La Roche	8-alkoxy-3,4-dihydroisoquinolines
SE368009B (no) *	1971-09-16	1974-06-17	Kabi Ab
US4117144A (en) *	1971-09-16	1978-09-26	Ab Kabi	Derivatives of substituted isoindolines with effect on the central nervous system
US4123543A (en) *	1971-09-16	1978-10-31	Ab Kabi	Derivatives of substituted indoline lactans with effect on the central nervous system
JPS6363851A (ja) *	1986-09-05	1988-03-22	孫七瓦工業株式会社	瓦の葺設方法
ATE110565T1 (de) *	1989-10-17	1994-09-15	Oklahoma Med Res Found	Verfahren und zubereitungen zur hemmung von mit oxidativer schädigung assoziierten krankheiten.
ATE209908T1 (de) *	1991-06-18	2001-12-15	Oklahoma Med Res Found	RADIKALFÄNGER (ßSPIN TRAPSß) ZUR BEHANDLUNG VON MIT OXIDATION VON LIPIDEN UND PROTEINEN VERBUNDENEN ERKRANKUNGEN
TW257755B (no) *	1991-09-12	1995-09-21	Merrell Dow Pharma
US5292746A (en) *	1991-09-12	1994-03-08	Merrell Dow Pharmaceuticals Inc.	Cyclic nitrones, pharmaceutical compositions thereof and their use in treating shock
US5455272A (en) *	1993-10-22	1995-10-03	Oklahoma Medical Research Foundation	Spin trap nitronyl hindered phenols
US5405967A (en) *	1993-10-22	1995-04-11	Oklahoma Medical Research Foundation	Spin-trap molecules 2-trifluoromethyl- of 5,5-dimethyl-1-dyrroline-N-oxide
WO1995011908A1 (en) *	1993-10-25	1995-05-04	Oklahoma Medical Research Foundation	Novel phosphorus-containing spin-trap compositions
US5488145A (en) *	1993-12-23	1996-01-30	Oklahoma Medical Research Foundation	2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps
US5472983A (en) *	1994-04-14	1995-12-05	Centaur Pharmaceuticals, Inc.	Benzamide-containing pharmaceutical compositions

1996
- 1996-08-15 AT AT02024174T patent/ATE293604T1/de not_active IP Right Cessation
- 1996-08-15 CN CNA200310104609A patent/CN1500779A/zh active Pending
- 1996-08-15 MX MX9801892A patent/MX9801892A/es not_active IP Right Cessation
- 1996-08-15 ES ES96928900T patent/ES2185797T3/es not_active Expired - Lifetime
- 1996-08-15 IL IL12334596A patent/IL123345A/xx not_active IP Right Cessation
- 1996-08-15 AT AT96928900T patent/ATE230731T1/de not_active IP Right Cessation
- 1996-08-15 CN CNB96196877XA patent/CN1250528C/zh not_active Expired - Fee Related
- 1996-08-15 PT PT02024174T patent/PT1288203E/pt unknown
- 1996-08-15 EP EP96928900A patent/EP0863878B1/en not_active Expired - Lifetime
- 1996-08-15 CN CNA200310104608A patent/CN1500787A/zh not_active Withdrawn
- 1996-08-15 NZ NZ316288A patent/NZ316288A/xx unknown
- 1996-08-15 KR KR1019980701806A patent/KR100512675B1/ko not_active IP Right Cessation
- 1996-08-15 CA CA002231812A patent/CA2231812C/en not_active Expired - Fee Related
- 1996-08-15 WO PCT/US1996/013312 patent/WO1997010218A1/en not_active Application Discontinuation
- 1996-08-15 DK DK02024174T patent/DK1288203T3/da active
- 1996-08-15 ES ES02024174T patent/ES2239194T3/es not_active Expired - Lifetime
- 1996-08-15 DE DE69634647T patent/DE69634647T2/de not_active Expired - Fee Related
- 1996-08-15 HU HU9803028A patent/HUP9803028A3/hu unknown
- 1996-08-15 DE DE69625701T patent/DE69625701T2/de not_active Expired - Fee Related
- 1996-08-15 PT PT96928900T patent/PT863878E/pt unknown
- 1996-08-15 DK DK96928900T patent/DK0863878T3/da active
- 1996-08-15 JP JP9511955A patent/JPH11512427A/ja not_active Ceased
- 1996-08-15 AU AU68486/96A patent/AU701989B2/en not_active Ceased
- 1996-09-05 ZA ZA967514A patent/ZA967514B/xx unknown
- 1996-09-06 TW TW085110921A patent/TW337520B/zh active
- 1996-09-09 AR ARP960104278A patent/AR004950A1/es not_active Application Discontinuation
1997
- 1997-11-26 US US08/978,971 patent/US5962469A/en not_active Expired - Fee Related
1998
- 1998-03-10 NO NO19981054A patent/NO311357B1/no unknown

Also Published As

Publication number	Publication date
DE69634647D1 (de)	2005-05-25
DE69625701T2 (de)	2003-10-02
CN1500787A (zh)	2004-06-02
PT863878E (pt)	2003-04-30
PT1288203E (pt)	2005-08-31
CA2231812A1 (en)	1997-03-20
EP0863878B1 (en)	2003-01-08
AU6848696A (en)	1997-04-01
HUP9803028A2 (hu)	1999-04-28
IL123345A (en)	2003-07-31
ES2239194T3 (es)	2005-09-16
EP0863878A1 (en)	1998-09-16
NO311357B1 (no)	2001-11-19
WO1997010218A1 (en)	1997-03-20
MX9801892A (es)	1998-05-31
NZ316288A (en)	2000-01-28
AU701989B2 (en)	1999-02-11
CA2231812C (en)	2002-08-06
CN1196050A (zh)	1998-10-14
NO981054L (no)	1998-03-10
DK0863878T3 (da)	2003-04-22
HUP9803028A3 (en)	1999-05-28
JPH11512427A (ja)	1999-10-26
TW337520B (en)	1998-08-01
US5962469A (en)	1999-10-05
AR004950A1 (es)	1999-04-07
DE69634647T2 (de)	2006-03-02
CN1250528C (zh)	2006-04-12
ATE293604T1 (de)	2005-05-15
ZA967514B (en)	1997-03-10
ES2185797T3 (es)	2003-05-01
ATE230731T1 (de)	2003-01-15
KR19990044557A (ko)	1999-06-25
CN1500779A (zh)	2004-06-02
DE69625701D1 (de)	2003-02-13
DK1288203T3 (da)	2005-07-11
IL123345A0 (en)	1998-09-24
KR100512675B1 (ko)	2006-08-10

Publication	Publication Date	Title
NO305316B1 (no)	1999-05-10	Nye substituerte 1H-imidazoler og farmas°ytiske preparater inneholdende disse
IS4644A (is)	1997-12-30	Setin bensýlamínópíperidín efnasambönd og lyfjablöndur þeirra
NO965376D0 (no)	1996-12-13	Farmasötiske preparater og metoder for formulering av signaltransduksjon
NO943511L (no)	1995-03-23	Farmasöytiske preparater og anvendelse derav
DK1167364T3 (da)	2003-08-11	Benzopyranholdige forbindelser og promedikamentformer af disse
DK0470514T3 (da)	1997-03-17	Carbostyrilderivater og farmaceutiske præparater indeholdende disse
DK108388A (da)	1988-09-03	Piperazinylalkylheterocycliske forbindelser og farmaceutiske praeparater indeholdende disse
NO993868D0 (no)	1999-08-11	3-piperidyl-4-oksokinazolin-derivater og medisinske preparater som inneholder slike
DK0729956T3 (da)	2001-11-26	Benzothi9phenforbindelser, emllemprodukter, præparater og fremgangsmåder
DK0847391T3 (da)	2002-03-25	Aromatiske forbindelse og farmaceutiske præparater indeholdende disse
NO981241D0 (no)	1998-03-19	Heteroarylsubstituerte akryloylguanidinderivater og farmasöytiske preparater inneholdende disse
DK0863878T3 (da)	2003-04-22	Cycliske nitroner og farmaceutiske præparater indeholdende disse
DK78888A (da)	1988-08-18	Arylpiperazinylalkylenphenyl-heterocycliske forbindelser og farmaceutiske praeparater indeholdende disse
DK650089D0 (da)	1989-12-20	Furanalkylketoner og farmaceutiske praeparater deraf
DK0385467T3 (da)	1994-07-04	Muramylpeptidderivater og immunregulerende præparater indeholdende disse
DK0828733T3 (da)	2001-12-17	Benzopyraner og farmaceutiske præparater indeholdende dem
NO972023D0 (no)	1997-04-30	Benzisoksasolderivater og pesticidpreparater inneholdende disse
NO994764D0 (no)	1999-09-30	Nye pyridinderivater og farmasöytiske preparater inneholdende disse
NO305943B1 (no)	1999-08-23	Klorfluoretersammensetninger og preparater av disse
DK160944C (da)	1991-10-21	Modificerede beta2-mikroglobuliner og farmaceutiske praeparater indeholdende disse
DK130890A (da)	1990-05-28	Peptider og farmaceutiske midler indeholdende disse
NO992316D0 (no)	1999-05-12	Benzensulfonamidderivater og legemidler inneholdende disse
NO179514C (no)	1996-10-23	Sykliske nitroner og farmasöytisk preparat inneholdende disse
HUP9602220A2 (en)	1997-05-28	Substituted 4h-piranes and pharmaceutical preparations containing them
NO970895D0 (no)	1997-02-27	Fenylpeptider, fremgangsmåte for fremstilling av disse, og farmasöytiske preparater inneholdende disse peptider