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NO980856D0 - Piperazinderivater og fremgangsmåte for fremstilling derav - Google Patents

Piperazinderivater og fremgangsmåte for fremstilling derav

Info

Publication number
NO980856D0
NO980856D0 NO980856A NO980856A NO980856D0 NO 980856 D0 NO980856 D0 NO 980856D0 NO 980856 A NO980856 A NO 980856A NO 980856 A NO980856 A NO 980856A NO 980856 D0 NO980856 D0 NO 980856D0
Authority
NO
Norway
Prior art keywords
substituted
unsubstituted
pct
alkyl
thioalkoxy
Prior art date
Application number
NO980856A
Other languages
English (en)
Other versions
NO980856L (no
NO311616B1 (no
Inventor
Eui-Hwan Cho
Sun-Gan Chung
Sun-Hwan Lee
Ho-Seok Kwon
Jae-Eung Lee
Dong-Wook Kang
Jeong-Ho Joo
Young-Hee Lee
Original Assignee
Samjin Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1019970022984A external-priority patent/KR100204320B1/ko
Priority claimed from KR1019970022985A external-priority patent/KR100204319B1/ko
Priority claimed from KR1019970023193A external-priority patent/KR100197111B1/ko
Priority claimed from KR1019970023192A external-priority patent/KR100204318B1/ko
Application filed by Samjin Pharm Co Ltd filed Critical Samjin Pharm Co Ltd
Publication of NO980856D0 publication Critical patent/NO980856D0/no
Publication of NO980856L publication Critical patent/NO980856L/no
Publication of NO311616B1 publication Critical patent/NO311616B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Quinoline Compounds (AREA)
NO19980856A 1996-06-29 1998-02-27 Piperazinderivater og fremgangsmåte for fremstilling derav NO311616B1 (no)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
KR19960025826 1996-06-29
KR19960025827 1996-06-29
KR19960025825 1996-06-29
KR19960040596 1996-09-18
KR1019970022984A KR100204320B1 (ko) 1996-06-29 1997-06-03 신규 피페라진 유도체 및 그 제조방법
KR1019970022985A KR100204319B1 (ko) 1996-06-29 1997-06-03 신규 피페라진 유도체 및 그 제조방법
KR1019970023193A KR100197111B1 (ko) 1996-09-18 1997-06-04 신규 피페라진 유도체 및 그 제조방법
KR1019970023192A KR100204318B1 (ko) 1996-06-29 1997-06-04 신규 피페라진 유도체 및 그 제조방법
PCT/KR1997/000128 WO1998000402A1 (en) 1996-06-29 1997-06-28 Piperazine derivatives and process for the preparation thereof

Publications (3)

Publication Number Publication Date
NO980856D0 true NO980856D0 (no) 1998-02-27
NO980856L NO980856L (no) 1998-04-27
NO311616B1 NO311616B1 (no) 2001-12-17

Family

ID=27573799

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19980856A NO311616B1 (no) 1996-06-29 1998-02-27 Piperazinderivater og fremgangsmåte for fremstilling derav

Country Status (17)

Country Link
US (1) US6028195A (no)
EP (1) EP0850222B1 (no)
JP (1) JP3032303B2 (no)
CN (1) CN1152015C (no)
AT (1) ATE241600T1 (no)
AU (1) AU713171B2 (no)
BG (1) BG102286A (no)
CA (1) CA2230960C (no)
CZ (1) CZ59398A3 (no)
DE (1) DE69722360T2 (no)
NO (1) NO311616B1 (no)
NZ (1) NZ329847A (no)
PL (1) PL325341A1 (no)
RU (1) RU2146254C1 (no)
SK (1) SK27598A3 (no)
TR (1) TR199800371T1 (no)
WO (1) WO1998000402A1 (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1129581C (zh) 1998-09-22 2003-12-03 山之内制药株式会社 氰基苯基衍生物
US20020065296A1 (en) 1999-01-13 2002-05-30 Bayer Corporation Heteroaryl ureas containing nitrogen hetero-atoms as p38 kinase inhibitors
CA2549558C (en) 1999-01-13 2010-08-31 Bayer Corporation Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
AU2725000A (en) 1999-01-13 2000-08-01 Bayer Corporation Omega-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
WO2000052001A1 (en) * 1999-03-03 2000-09-08 Samjin Pharmaceutical Co., Ltd. Piperazine derivatives and process for the preparation thereof
MXPA03000458A (es) 2000-07-20 2004-06-02 Neurogen Corp Ligandos receptores de capsaicina.
DE10035908A1 (de) * 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
DE10035928A1 (de) 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
DE10035927A1 (de) 2000-07-21 2002-03-07 Asta Medica Ag Neue Heteroaryl-Derivate und deren Verwendung als Arzneimittel
WO2002084285A2 (en) 2001-04-18 2002-10-24 Krull Ulrich J Gradient resolved hybridisation platform
JP4583760B2 (ja) 2002-02-01 2010-11-17 ユーロ−セルティーク エス.エイ. 疼痛の治療に有用な治療薬
CA2491079C (en) 2002-06-28 2011-10-04 Donald J. Kyle Therapeutic piperazine derivatives useful for treating pain
BR0312294A (pt) * 2002-06-29 2005-04-12 Zentaris Gmbh Arilcarbonil piperazinas e hteroarilcarbonilpiperazinas e o uso das mesmas para tratamento de doenças benignas e malignas
US7262194B2 (en) * 2002-07-26 2007-08-28 Euro-Celtique S.A. Therapeutic agents useful for treating pain
US7157462B2 (en) 2002-09-24 2007-01-02 Euro-Celtique S.A. Therapeutic agents useful for treating pain
AU2004218260A1 (en) * 2003-01-28 2004-09-16 Aventis Pharma S.A. N-aryl heteroaromatic products, compositions containing same and use thereof
US20050130989A1 (en) * 2003-01-28 2005-06-16 Aventis Pharma S. A. N-arylheteroaromatic products compositions containing them and use thereof
JP2007511203A (ja) 2003-05-20 2007-05-10 バイエル、ファーマシューテイカルズ、コーポレイション キナーゼ阻害活性を有するジアリール尿素
WO2006054830A1 (en) 2004-11-17 2006-05-26 Rexahn Pharmaceuticals, Inc. 1-[(6,7-substituted alkoxyquinoxalinyl)aminocarbonyl]-4-(hetero)arylpiperazine derivatives
WO2007020888A1 (ja) 2005-08-12 2007-02-22 Takeda Pharmaceutical Company Limited 脳・神経細胞保護剤および睡眠障害治療薬
CA2627875A1 (en) 2005-10-31 2007-05-10 Bayer Pharmaceuticals Corporation Combinations comprising sorafenib and interferon for the treatment of cancer
US20100234389A1 (en) * 2007-10-10 2010-09-16 Takeda Pharmaceutical Company Limited Amide compound
US7946206B2 (en) * 2007-11-21 2011-05-24 Rocksmart, Llc Quick-release system
TWI434842B (zh) * 2008-07-14 2014-04-21 Astellas Pharma Inc Azole compounds
EP2956441A4 (en) * 2013-02-18 2016-11-02 Scripps Research Inst MODULATORS OF VASOPRESSIN RECEPTORS WITH THERAPEUTIC POTENTIAL
CN109071504B (zh) 2016-02-05 2022-03-08 戴纳立制药公司 受体相互作用蛋白激酶1的抑制剂
PL3552017T3 (pl) 2016-12-09 2022-08-08 Denali Therapeutics Inc. Związki użyteczne jako inhibitory RIPK1
MX2024008648A (es) 2022-01-12 2024-09-23 Denali Therapeutics Inc Formas cristalinas de (s)-5-bencil-n-(5-metil-4-oxo-2,3,4,5-tetrah idropirido [3,2- b][1,4]oxacepin-3-il)-4h-1,2,4-triazol-3-carboxam ida.

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
US4038391A (en) * 1973-05-15 1977-07-26 Rhone-Poulenc S.A. 6-(1,8-Naphthyridin-2-yl)-5-piperazino carbonyloxy-7-oxo-6,7-dihydro-5H-pyrrolo-[3,4-b]pyrazines and related pyridines
OA04700A (fr) * 1973-05-15 1980-07-31 Rhone Poulenc Sa Nouveaux dérivés de la naphtyridine et leur procédé de préparation.
US4016274A (en) * 1973-05-15 1977-04-05 Rhone-Poulenc S.A. Naphthyridine derivatives
JPS63115167A (ja) * 1986-10-31 1988-05-19 Konica Corp ハロゲン化銀写真感光材料
US5391571A (en) * 1989-11-15 1995-02-21 American Home Products Corporation Cholesterol ester hydrolase inhibitors
DE4018070A1 (de) * 1990-06-06 1991-12-12 Bayer Ag Morpholinoharnstoff-derivate
ZA929008B (en) * 1991-12-13 1993-05-21 Bristol Myers Squibb Co Piperazinyl- and piperidinyl-cyclohexanols.
DE4216364A1 (de) * 1991-12-14 1993-11-25 Thomae Gmbh Dr K Neue Pyridylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5461047A (en) * 1993-06-16 1995-10-24 G. D. Searle & Co. 2-,3-,4-,5-,6-,7-,8-,9- and/or 10-substituted dibenzoxazepine and dibenzthiazepine compounds, pharmaceutical compositions and methods of use
FR2722788B1 (fr) * 1994-07-20 1996-10-04 Pf Medicament Nouvelles piperazides derivees d'aryl piperazine, leurs procedes de preparation, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant
BR9605309A (pt) * 1995-01-11 1997-10-14 Samjin Pharmaceutical Co Composições de derivados piperazina

Also Published As

Publication number Publication date
TR199800371T1 (xx) 1998-06-22
EP0850222B1 (en) 2003-05-28
WO1998000402A1 (en) 1998-01-08
AU713171B2 (en) 1999-11-25
CA2230960C (en) 2007-08-28
DE69722360D1 (de) 2003-07-03
BG102286A (en) 1999-08-31
EP0850222A1 (en) 1998-07-01
JP3032303B2 (ja) 2000-04-17
RU2146254C1 (ru) 2000-03-10
SK27598A3 (en) 1998-11-04
NZ329847A (en) 1999-01-28
ATE241600T1 (de) 2003-06-15
AU3464297A (en) 1998-01-21
NO980856L (no) 1998-04-27
NO311616B1 (no) 2001-12-17
DE69722360T2 (de) 2003-11-27
PL325341A1 (en) 1998-07-20
US6028195A (en) 2000-02-22
CN1196724A (zh) 1998-10-21
CA2230960A1 (en) 1998-01-08
CN1152015C (zh) 2004-06-02
JPH11501680A (ja) 1999-02-09
CZ59398A3 (cs) 1998-07-15

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