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NO975387L - Fremgangsmåte for fremstilling av 3-haloalkyl-1H-pyrazoler - Google Patents

Fremgangsmåte for fremstilling av 3-haloalkyl-1H-pyrazoler

Info

Publication number
NO975387L
NO975387L NO975387A NO975387A NO975387L NO 975387 L NO975387 L NO 975387L NO 975387 A NO975387 A NO 975387A NO 975387 A NO975387 A NO 975387A NO 975387 L NO975387 L NO 975387L
Authority
NO
Norway
Prior art keywords
pyrazoles
haloalkyl
preparation
adoption
safe
Prior art date
Application number
NO975387A
Other languages
English (en)
Other versions
NO311130B1 (no
NO975387D0 (no
Inventor
Benxin Zhi
Murad Newaz
John J Talley
Stephen R Bertenshaw
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of NO975387D0 publication Critical patent/NO975387D0/no
Publication of NO975387L publication Critical patent/NO975387L/no
Publication of NO311130B1 publication Critical patent/NO311130B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO19975387A 1995-05-25 1997-11-24 Fremgangsmåte for fremstilling av 3-haloalkyl-1H-pyrazoler NO311130B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44997595A 1995-05-25 1995-05-25
PCT/US1996/007506 WO1996037476A1 (en) 1995-05-25 1996-05-23 Method of preparing 3-haloalkyl-1h-pyrazoles

Publications (3)

Publication Number Publication Date
NO975387D0 NO975387D0 (no) 1997-11-24
NO975387L true NO975387L (no) 1997-12-17
NO311130B1 NO311130B1 (no) 2001-10-15

Family

ID=23786237

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19975387A NO311130B1 (no) 1995-05-25 1997-11-24 Fremgangsmåte for fremstilling av 3-haloalkyl-1H-pyrazoler

Country Status (20)

Country Link
US (2) US5892053A (no)
EP (1) EP0828717B1 (no)
JP (1) JP3996638B2 (no)
KR (1) KR100444802B1 (no)
CN (1) CN1174970C (no)
AT (1) ATE223383T1 (no)
AU (1) AU708964B2 (no)
BR (1) BR9609043A (no)
CA (1) CA2222138C (no)
CZ (1) CZ292320B6 (no)
DE (1) DE69623460T2 (no)
DK (1) DK0828717T3 (no)
ES (1) ES2182991T3 (no)
NO (1) NO311130B1 (no)
NZ (1) NZ308875A (no)
PL (1) PL187410B1 (no)
PT (1) PT828717E (no)
RO (1) RO118200B1 (no)
RU (2) RU2169143C2 (no)
WO (1) WO1996037476A1 (no)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6716991B1 (en) * 1993-11-30 2004-04-06 G. D. Searle & Co. Process for preparing a substituted pyrazolyl benzenesulfonamide for the treatment of inflammation
US6492411B1 (en) * 1993-11-30 2002-12-10 G. D. Searle & Co. Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation
US5466823A (en) 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
US6525053B1 (en) 1997-08-22 2003-02-25 Abbott Laboratories Prostaglandin endoperoxide H synthase biosynthesis inhibitors
US6307047B1 (en) 1997-08-22 2001-10-23 Abbott Laboratories Prostaglandin endoperoxide H synthase biosynthesis inhibitors
ES2137138B1 (es) * 1998-05-29 2000-09-16 Esteve Labor Dr Derivados de pirazolinas, su preparacion y su aplicacion como medicamentos.
US6727238B2 (en) * 1998-06-11 2004-04-27 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
US6294558B1 (en) 1999-05-31 2001-09-25 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
SA99191255B1 (ar) 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
AU760888B2 (en) * 1999-01-14 2003-05-22 Merck Frosst Canada & Co. Synthesis of 4-((5-substituted or unsubstituted phenyl) -3-substituted -1H-pyrazol -1-yl) benzenesulfonamides
PL203262B1 (pl) * 1999-12-08 2009-09-30 Pharmacia Corp Substancja lecznicza celekoksyb, jej zastosowanie i sposób jej wytwarzania, kompozyt celekoksyb-inhibitor krystalizacji i sposób jego wytwarzania, kompozycja farmaceutyczna i sposób jej wytwarzania
PL351944A1 (en) * 1999-12-08 2003-07-14 Pharmacia Corp Cyclooxygenase-2 inhibitor compositions having rapid onset of therapeutic effect
MY120279A (en) 2000-05-26 2005-09-30 Pharmacia Corp Use of a celecoxib composition for fast pain relief
TR200001872A3 (tr) * 2000-06-26 2002-01-21 Fako Ilaclari A.S 4-[5-(4-Metilfenil-3-(triflorometil)-1H-pirazol-1-il] benzensulfonamit' in yeni kristal biçimi "Biçim I" ve bu ürünün üretilmesine iliskin yöntem.
PE20020146A1 (es) * 2000-07-13 2002-03-31 Upjohn Co Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
CA2414674A1 (en) * 2000-07-13 2002-01-24 Pharmacia Corporation Use of cox-2 inhibitors in the treatment and prevention of ocular cox-2 mediated disorders
US20030219461A1 (en) * 2000-09-12 2003-11-27 Britten Nancy J. Parenteral combination therapy for infective conditions
US7115565B2 (en) * 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
US7695736B2 (en) 2001-04-03 2010-04-13 Pfizer Inc. Reconstitutable parenteral composition
OA12613A (en) * 2001-05-31 2006-06-09 Pharmacia Corp Skin-permeable composition comprising a selective cyclooxygenase-2 inhibitor a monohydric alcohol.
UA80682C2 (en) * 2001-08-06 2007-10-25 Pharmacia Corp Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
AU2002251330A1 (en) * 2002-04-25 2003-11-10 Generics (Uk) Limited Celecoxib forms
AU2003299482A1 (en) * 2002-05-13 2004-06-07 Pharmacia Corporation Stable amorphous celecoxib composite and process therefor
ZA200409434B (en) * 2002-05-24 2006-10-25 Pharmacia Corp Synthesis of diary pyrazoles
JP2004115436A (ja) * 2002-09-26 2004-04-15 Nippon Nohyaku Co Ltd ピラゾール誘導体の製造方法
US20080153894A1 (en) * 2002-12-19 2008-06-26 Pharmacia Corporation Cyclooxygenase-2 inhibitor and antibacterial agent combination for intramammary treatment of mastitis
US20050004098A1 (en) * 2003-03-20 2005-01-06 Britten Nancy Jean Dispersible formulation of an anti-inflammatory agent
US20040214753A1 (en) * 2003-03-20 2004-10-28 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
US20050009931A1 (en) * 2003-03-20 2005-01-13 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
JP2006520779A (ja) * 2003-03-20 2006-09-14 ファルマシア コーポレイション 抗炎症薬の分散性処方物
ES2257929B1 (es) * 2004-07-16 2007-05-01 Laboratorios Del Dr. Esteve, S.A. Derivados de pirazolina, procedimiento para su obtencion y utilizacion de los mismos como agentes terapeuticos.
CA2589167A1 (en) 2004-11-23 2006-06-01 Pliva Hrvatska D.O.O. Extended release pharmaceutical composition of celecoxib
WO2010095024A2 (en) 2009-02-20 2010-08-26 Aurobindo Pharma Limited An improved process for the preparation of celecoxib
WO2011055233A2 (en) 2009-11-03 2011-05-12 Actavis Group Ptc Ehf Improved process for preparing celecoxib polymorph
US20110213159A1 (en) 2010-03-01 2011-09-01 Vamsee Krishna Muppidi Process for preparation of celecoxib crystalline form
JP5909183B2 (ja) 2010-08-19 2016-04-26 国立大学法人 東京大学 オメガ３系脂肪酸由来の新規抗炎症性代謝物
CN102746231A (zh) * 2011-04-20 2012-10-24 天津药物研究院 塞来昔布制备工艺
CN103980201B (zh) * 2014-05-23 2016-02-10 苏州大学 一种含砜基的全取代吡唑的制备方法
CN110407683A (zh) * 2019-04-03 2019-11-05 湖南方盛制药股份有限公司 一种塞来昔布二酮中间体的制备方法
CN114292235B (zh) * 2021-12-29 2023-04-14 江苏天和制药有限公司 一种地拉考昔的制备和提纯方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA714221B (en) * 1970-07-10 1972-03-29 Astra Ab Insecticides
DE2429674A1 (de) * 1974-06-20 1976-01-08 Hoechst Ag Verfahren zur herstellung aromatischer 1,3-diketone
PH27357A (en) * 1989-09-22 1993-06-21 Fujisawa Pharmaceutical Co Pyrazole derivatives and pharmaceutical compositions comprising the same
KR0168056B1 (ko) * 1990-04-26 1999-03-20 베르너 발데크 선형 1,3-디케톤의 제조방법
US5344992A (en) * 1990-04-26 1994-09-06 Ciba-Geigy Corporation Process for the preparation of linear 1,3-diketones
IL104311A (en) * 1992-02-05 1997-07-13 Fujisawa Pharmaceutical Co Pyrazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
PT731795E (pt) * 1993-11-30 2000-05-31 Searle & Co Pirazolilbenzenossulfonamidas para o tratamento de inflamacoes
US5466823A (en) * 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides

Also Published As

Publication number Publication date
DE69623460D1 (de) 2002-10-10
WO1996037476A1 (en) 1996-11-28
AU708964B2 (en) 1999-08-19
PT828717E (pt) 2002-12-31
CN1174970C (zh) 2004-11-10
CA2222138A1 (en) 1996-11-28
EP0828717B1 (en) 2002-09-04
NZ308875A (en) 1999-08-30
MX9709065A (es) 1998-03-31
KR100444802B1 (ko) 2004-12-17
NO311130B1 (no) 2001-10-15
EP0828717A1 (en) 1998-03-18
DK0828717T3 (da) 2003-01-06
CA2222138C (en) 2008-10-14
ATE223383T1 (de) 2002-09-15
NO975387D0 (no) 1997-11-24
CZ368997A3 (cs) 1998-03-18
RU2169143C2 (ru) 2001-06-20
PL323492A1 (en) 1998-03-30
DE69623460T2 (de) 2003-02-27
RO118200B1 (ro) 2003-03-28
RU2251543C2 (ru) 2005-05-10
PL187410B1 (pl) 2004-07-30
CZ292320B6 (cs) 2003-09-17
AU5873696A (en) 1996-12-11
KR19990021966A (ko) 1999-03-25
JPH11505848A (ja) 1999-05-25
US5910597A (en) 1999-06-08
US5892053A (en) 1999-04-06
BR9609043A (pt) 1999-02-23
JP3996638B2 (ja) 2007-10-24
ES2182991T3 (es) 2003-03-16
CN1190960A (zh) 1998-08-19

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Legal Events

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