NO975130L - <alfa>-(substituerte alkylfenyl)-4-(hydroxydifenylmethyl)-1-piperidinbutanolderivater, deres fremstilling og deres anvendelse som antihistaminer, anti-allergimidler og bronchodilatorer - Google Patents

<alfa>-(substituerte alkylfenyl)-4-(hydroxydifenylmethyl)-1-piperidinbutanolderivater, deres fremstilling og deres anvendelse som antihistaminer, anti-allergimidler og bronchodilatorer

Info

Publication number: NO975130L
Authority: NO; Norway
Prior art keywords: piperidinebutanol; hydroxydiphenylmethyl; bronchodilators; antihistamines; alfa
Prior art date: 1995-05-08

Application number

NO975130A

Other languages

English (en)

Other versions

NO975130D0 (no

NO309649B1 (no

Inventor

Paul Wayne Brown

Kah Hiing Ling

Robert Michael Strom

Richard Appleby Wolf

Original Assignee

Hoechst Marion Roussel Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-08

Filing date

1997-11-07

Publication date

1998-01-06

1997-11-07 Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc

1997-11-07 Publication of NO975130D0 publication Critical patent/NO975130D0/no

1998-01-06 Publication of NO975130L publication Critical patent/NO975130L/no

2001-03-05 Publication of NO309649B1 publication Critical patent/NO309649B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Epidemiology (AREA)
Hydrogenated Pyridines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO975130A 1995-05-08 1997-11-07 <alfa>-(substituerte alkylfenyl)-4-(hydroxydifenylmethyl)-1- piperidinbutanolderivater og deres anvendelse til fremstilling av antihistaminer, anti-allergimidler og bronchodilatorer NO309649B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US43653595A	1995-05-08	1995-05-08
PCT/US1996/005243 WO1996035667A1 (en)	1995-05-08	1996-04-16	Alpha-(substituted alkylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidine butanol derivatives, their preparation and their use as anti-histamines, anti-allergy agents and bronchodilators

Publications (3)

Publication Number	Publication Date
NO975130D0 NO975130D0 (no)	1997-11-07
NO975130L true NO975130L (no)	1998-01-06
NO309649B1 NO309649B1 (no)	2001-03-05

Family

ID=23732797

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO975130A NO309649B1 (no)	1995-05-08	1997-11-07	<alfa>-(substituerte alkylfenyl)-4-(hydroxydifenylmethyl)-1- piperidinbutanolderivater og deres anvendelse til fremstilling av antihistaminer, anti-allergimidler og bronchodilatorer

Country Status (16)

Country	Link
US (4)	US20020016467A1 (no)
EP (1)	EP0871614A1 (no)
JP (1)	JPH11504650A (no)
KR (1)	KR19990008406A (no)
CN (1)	CN1183769A (no)
AR (1)	AR002293A1 (no)
AU (1)	AU705427B2 (no)
CA (1)	CA2216877A1 (no)
HU (1)	HUP9801254A3 (no)
IL (1)	IL118161A0 (no)
MX (1)	MX9708612A (no)
NO (1)	NO309649B1 (no)
NZ (1)	NZ306319A (no)
TW (1)	TW412527B (no)
WO (1)	WO1996035667A1 (no)
ZA (1)	ZA963483B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6683094B2 (en)	1998-07-02	2004-01-27	Aventis Pharmaceuticals Inc.	Antihistaminic piperidine derivatives and intermediates for the preparation thereof
US6930197B2 (en)	1998-07-02	2005-08-16	Aventis Pharmaceuticals Inc.	Antihistaminic piperidine derivatives and intermediates for the preparation thereof
CN100522921C (zh) *	1998-07-02	2009-08-05	阿旺蒂斯制药公司	抗组胺哌啶衍生物及制备其的中间体
AU2007200674C1 (en) *	1998-07-02	2011-02-24	Aventisub Llc	Novel antihistaminic piperidine derivatives and intermediates for the preparation thereof
PT1311482E (pt) *	2000-08-08	2007-04-30	Ortho Mcneil Pharm Inc	Ariloxipiperidinas não imidazólicas como ligandos do receptor h3
EP2578570A1 (en)	2011-10-07	2013-04-10	Almirall, S.A.	Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
EP2641900A1 (en)	2012-03-20	2013-09-25	Almirall, S.A.	Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
BR112016022829B1 (pt) *	2014-04-02	2022-03-03	Chembio Diagnostic Systems, Inc	Dispositivo de teste para determinar a presença de um primeiro ligante em uma amostra líquida, e método para testar uma amostra quanto à presença de um primeiro ligante

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3965257A (en) *	1972-01-28	1976-06-22	Richardson-Merrell Inc.	Compositions and methods for the treatment of the symptoms of histamine induced allergic reactions
US3878217A (en) *	1972-01-28	1975-04-15	Richardson Merrell Inc	Alpha-aryl-4-substituted piperidinoalkanol derivatives
ZA728544B (en) *	1972-01-28	1974-02-27	Richardson Merrell Inc	Alpha-aryl-4-substituted piperidinoalkanol derivatives
US3806526A (en) *	1972-01-28	1974-04-23	Richardson Merrell Inc	1-aroylalkyl-4-diphenylmethyl piperidines
US4285957A (en) *	1979-04-10	1981-08-25	Richardson-Merrell Inc.	1-Piperidine-alkanol derivatives, pharmaceutical compositions thereof, and method of use thereof
US4254129A (en) *	1979-04-10	1981-03-03	Richardson-Merrell Inc.	Piperidine derivatives
US4254130A (en) *	1979-04-10	1981-03-03	Richardson-Merrell Inc.	Piperidine derivatives
US4285958A (en) *	1979-04-10	1981-08-25	Richardson-Merrell Inc.	1-Piperidine-alkylene ketones, pharmaceutical compositions thereof and method of use thereof
GB8321157D0 (en) *	1983-08-05	1983-09-07	Fordonal Sa	Piperidine derivatives
IT1205685B (it) *	1987-05-26	1989-03-31	Erregierre Spa	Processo per la preparazione di alfa-(alchilfenil)-4-(idrossi difenilmetil)-1-piperidina butanolo
US4863931A (en) *	1988-09-15	1989-09-05	Schering Corporation	Antihistaminic fluoro substituted benzocycloheptapyridines
CN1168717C (zh) *	1993-06-25	2004-09-29	默里尔药物公司	用于制备抗组胺哌啶衍生物的新中间体
US6174216B1 (en) *	1999-08-03	2001-01-16	Mattel, Inc.	Stretchable two-headed toy figure

1996
- 1996-04-16 JP JP8534075A patent/JPH11504650A/ja not_active Ceased
- 1996-04-16 CN CN96193789A patent/CN1183769A/zh active Pending
- 1996-04-16 KR KR1019970707933A patent/KR19990008406A/ko not_active Application Discontinuation
- 1996-04-16 NZ NZ306319A patent/NZ306319A/xx not_active IP Right Cessation
- 1996-04-16 HU HU9801254A patent/HUP9801254A3/hu unknown
- 1996-04-16 AU AU54860/96A patent/AU705427B2/en not_active Ceased
- 1996-04-16 CA CA002216877A patent/CA2216877A1/en not_active Abandoned
- 1996-04-16 EP EP96911782A patent/EP0871614A1/en not_active Withdrawn
- 1996-04-16 WO PCT/US1996/005243 patent/WO1996035667A1/en not_active Application Discontinuation
- 1996-04-16 MX MX9708612A patent/MX9708612A/es unknown
- 1996-05-02 ZA ZA963483A patent/ZA963483B/xx unknown
- 1996-05-03 AR ARP960102432A patent/AR002293A1/es not_active Application Discontinuation
- 1996-05-03 TW TW085105337A patent/TW412527B/zh active
- 1996-05-06 IL IL11816196A patent/IL118161A0/xx unknown
1997
- 1997-11-07 NO NO975130A patent/NO309649B1/no not_active IP Right Cessation
2001
- 2001-10-02 US US09/968,961 patent/US20020016467A1/en not_active Abandoned
2002
- 2002-10-03 US US10/263,869 patent/US20030065186A1/en not_active Abandoned
2004
- 2004-03-01 US US10/790,284 patent/US20040167169A1/en not_active Abandoned
2005
- 2005-06-09 US US11/149,106 patent/US20050239834A1/en not_active Abandoned

Also Published As

Publication number	Publication date
HUP9801254A3 (en)	1998-09-28
AU5486096A (en)	1996-11-29
WO1996035667A1 (en)	1996-11-14
AR002293A1 (es)	1998-03-11
MX9708612A (es)	1998-02-28
NZ306319A (en)	1999-08-30
CA2216877A1 (en)	1996-11-14
ZA963483B (en)	1996-11-13
US20050239834A1 (en)	2005-10-27
EP0871614A1 (en)	1998-10-21
US20030065186A1 (en)	2003-04-03
TW412527B (en)	2000-11-21
US20040167169A1 (en)	2004-08-26
CN1183769A (zh)	1998-06-03
KR19990008406A (ko)	1999-01-25
HUP9801254A2 (hu)	1998-08-28
US20020016467A1 (en)	2002-02-07
AU705427B2 (en)	1999-05-20
JPH11504650A (ja)	1999-04-27
NO975130D0 (no)	1997-11-07
IL118161A0 (en)	1996-09-12
NO309649B1 (no)	2001-03-05

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Legal Events

Date	Code	Title	Description
2013-12-02	MM1K	Lapsed by not paying the annual fees