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NO965305D0 - Nye forbindelser, fremgangsmåter ved deres fremstilling og anti-tumormidler - Google Patents

Nye forbindelser, fremgangsmåter ved deres fremstilling og anti-tumormidler

Info

Publication number
NO965305D0
NO965305D0 NO965305A NO965305A NO965305D0 NO 965305 D0 NO965305 D0 NO 965305D0 NO 965305 A NO965305 A NO 965305A NO 965305 A NO965305 A NO 965305A NO 965305 D0 NO965305 D0 NO 965305D0
Authority
NO
Norway
Prior art keywords
hydrogen atom
preparation
tumor agents
methods
group
Prior art date
Application number
NO965305A
Other languages
English (en)
Other versions
NO307255B1 (no
NO965305L (no
Inventor
Kyoji Tomita
Katsumi Chiba
Shigeki Kashimoto
Koh-Ichiro Shibamori
Yasunori Tsuzuki
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of NO965305D0 publication Critical patent/NO965305D0/no
Publication of NO965305L publication Critical patent/NO965305L/no
Publication of NO307255B1 publication Critical patent/NO307255B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO965305A 1994-06-14 1996-12-11 Nye forbindelser og antitumormidler NO307255B1 (no)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP15657894 1994-06-14
JP19792194 1994-07-28
JP30691494 1994-11-15
JP33995694 1994-12-28
JP8170595 1995-03-13
PCT/JP1995/001110 WO1995034559A1 (fr) 1994-06-14 1995-06-06 Nouveau compose, son procede de production et agent antitumoral

Publications (3)

Publication Number Publication Date
NO965305D0 true NO965305D0 (no) 1996-12-11
NO965305L NO965305L (no) 1997-02-04
NO307255B1 NO307255B1 (no) 2000-03-06

Family

ID=27524935

Family Applications (1)

Application Number Title Priority Date Filing Date
NO965305A NO307255B1 (no) 1994-06-14 1996-12-11 Nye forbindelser og antitumormidler

Country Status (27)

Country Link
US (1) US5817669A (no)
EP (1) EP0787726B1 (no)
JP (1) JP3391796B2 (no)
KR (1) KR100350921B1 (no)
CN (1) CN1053668C (no)
AT (1) ATE209645T1 (no)
AU (1) AU679859B2 (no)
BR (1) BR9508037A (no)
CA (1) CA2192824C (no)
CZ (1) CZ292631B6 (no)
DE (1) DE69524251T2 (no)
DK (1) DK0787726T3 (no)
ES (1) ES2163512T3 (no)
FI (1) FI112485B (no)
HK (1) HK1000495A1 (no)
HU (1) HU220072B (no)
MX (1) MX9606331A (no)
NO (1) NO307255B1 (no)
NZ (1) NZ287139A (no)
PL (1) PL181867B1 (no)
PT (1) PT787726E (no)
RO (1) RO117793B1 (no)
RU (1) RU2151770C1 (no)
SI (1) SI0787726T1 (no)
SK (1) SK281341B6 (no)
TW (1) TW319769B (no)
WO (1) WO1995034559A1 (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1578781A (zh) 2001-09-26 2005-02-09 拜尔药品公司 用作抗糖尿病药物的1,8-萘啶衍生物
US6802423B2 (en) * 2002-02-20 2004-10-12 Trans Global Foods, Inc. Disposable food delivery apparatus
WO2004091627A2 (en) * 2003-04-07 2004-10-28 Cylene Pharmaceuticals, Inc. Heterocyclic substituted 1,4-dihydro-4-oxo-1,8-naphthpyridine analogs
SG144936A1 (en) * 2003-09-10 2008-08-28 Kyorin Seiyaku Kk 7-(4-substituted-3-cyclopropylaminomethyl-1- pyrrolidinyl)quinolonecarboxylic acid derivative
DE10352979A1 (de) * 2003-11-13 2005-06-09 Merck Patent Gmbh Pyridopyrimidinone
AU2013201203C1 (en) * 2004-03-15 2015-04-23 Sumitomo Dainippon Pharma Co., Ltd. Sns-595 and methods of using the same
EP1729770B1 (en) * 2004-03-15 2009-12-16 Sunesis Pharmaceuticals, Inc. Sns-595 and methods of using the same
US7563805B2 (en) * 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
CA2619663A1 (en) * 2005-08-19 2007-02-22 Cylene Pharmaceuticals, Inc. Human ribosomal dna(rdna) and ribosomal rna (rrna) nucleic acids and uses thereof
CN104873502A (zh) * 2005-09-02 2015-09-02 逊尼希思制药公司 使用(+)-1,4-二氢-7-[(3s,4s)-3-甲氧基-4-(甲氨基)-1-吡咯烷基]-4-氧代-1-(2-噻唑基)-1,8-萘啶-3-羧酸治疗癌症的方法
JP5374153B2 (ja) * 2005-09-02 2013-12-25 サネシス ファーマシューティカルズ, インコーポレイテッド 癌の治療のための(+)−1,4−ジヒドロ−7−[(3s,4s)−3−メトキシ−4−(メチルアミノ)−1−ピロリジニル]−4−オキソ−1−(2−チアゾリル)−1,8−ナフチリジン−3−カルボン酸を使用する方法
US8580814B2 (en) * 2006-04-03 2013-11-12 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4- oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
AU2013219242C1 (en) * 2005-09-02 2016-09-22 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
EP1931339B1 (en) * 2005-09-02 2018-05-16 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of cancer
TW200800983A (en) 2005-09-14 2008-01-01 Janssen Pharmaceutica Nv 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of C-FMS kinase
US7642270B2 (en) 2005-09-14 2010-01-05 Janssen Pharmaceutica N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidine as inhibitors of c-fms kinase
WO2007033232A1 (en) * 2005-09-14 2007-03-22 Janssen Pharmaceutica, N.V. 5-oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of c-fms kinase
EP2354138A1 (en) * 2006-06-12 2011-08-10 Sunesis Pharmaceuticals, Inc. Compounds and compositions for treatment of cancer
US20100048609A1 (en) * 2006-08-01 2010-02-25 Jacobs Jeffrey W Pharmaceutical dosage forms for (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
CA2659861A1 (en) 2006-08-02 2008-02-07 Sunesis Pharmaceuticals, Inc. Methods of using (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for treatment of certain hematologic disorders
MX2010004350A (es) * 2007-10-22 2010-05-19 Sunesis Pharmaceuticals Inc Metodos de uso del acido (+)-1,4-dihidro-7-[(3s,4s)]-3-metoxi-4-(m etilamino)-1-pirrolidinil-4-oxo-1-(2-tiazolil)-1, 8-naftiridina-3-carboxilico en terapias de combinacion.
EP2649997B1 (en) * 2007-12-10 2019-01-23 Sunesis Pharmaceuticals, Inc. (+)-1,4-dihydro-7-[(3s,4s)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid for use in the treatment of myelodyspastic syndrome
RU2015106671A (ru) * 2008-12-31 2015-06-27 Санесис Фармасьютикалз, Инк. Способ получения (+)-1,4-дигидро-7-[(3s,4s)-3-метокси-4-(метиламино)-1-пирролидинил]-4-оксо-1-(2-тиазолил)-1,8-нафтиридин-3-карбоновой кислоты
NZ594829A (en) 2009-02-27 2013-09-27 Sunesis Pharmaceuticals Inc Methods of using sns-595 for treatment of cancer subjects with reduced brca2 activity
UA110465C2 (en) 2009-09-04 2016-01-12 Sunesis Pharmaceutecals Inc Stable sns-595 composition
US8470817B2 (en) * 2009-10-26 2013-06-25 Sunesis Pharmaceuticals, Inc. Compounds and methods for treatment of cancer
MX369142B (es) 2011-05-13 2019-10-30 Array Biopharma Inc Compuestos intermediarios de fórmula ii, útiles en la preparación de compuestos derivados de pirrolidinil como inhibidores de cinasa trka.
CN103497186B (zh) * 2013-09-24 2015-02-25 浙江司太立制药股份有限公司 含有烷氧亚氨基取代的萘啶酮羧酸衍生物及其制备方法
JP7518618B2 (ja) * 2017-03-24 2024-07-18 湧永製薬株式会社 新規ピリドンカルボン酸誘導体又はその塩

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4730000A (en) * 1984-04-09 1988-03-08 Abbott Laboratories Quinoline antibacterial compounds
DE3577089D1 (de) * 1984-01-26 1990-05-17 Abbott Lab Antibakterielle chinolinderivate.
NZ210847A (en) * 1984-01-26 1988-02-29 Abbott Lab Naphthyridine and pyridopyrimidine derivatives and pharmaceutical compositions
JPS61152682A (ja) * 1984-12-27 1986-07-11 Dainippon Pharmaceut Co Ltd ピリドンカルボン酸誘導体、そのエステルおよびその塩
JPS61251667A (ja) * 1985-04-30 1986-11-08 Otsuka Pharmaceut Co Ltd ベンゾヘテロ環化合物
GR861530B (en) * 1985-06-13 1986-12-31 Schering Corp Preparation process for polycyclic quinoline of naphthyridine and pyrazinopyridine
WO1986007357A2 (en) * 1985-06-14 1986-12-18 Upjohn Co Cyclopentapyrazole and tetrahydroindazole compounds
JPS6233176A (ja) * 1985-08-05 1987-02-13 Toyama Chem Co Ltd 1,4−ジヒドロ−4−オキソナフチリジン誘導体およびその塩
JP2704428B2 (ja) * 1988-06-15 1998-01-26 富山化学工業株式会社 キノロンカルボン酸誘導体またはその塩
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
JPH06233176A (ja) * 1993-01-29 1994-08-19 Sony Corp ビデオカメラ

Also Published As

Publication number Publication date
DK0787726T3 (da) 2002-02-11
TW319769B (no) 1997-11-11
EP0787726B1 (en) 2001-11-28
AU679859B2 (en) 1997-07-10
RO117793B1 (ro) 2002-07-30
SK281341B6 (sk) 2001-02-12
RU2151770C1 (ru) 2000-06-27
CN1053668C (zh) 2000-06-21
EP0787726A4 (no) 1997-08-06
DE69524251T2 (de) 2002-07-11
SK157496A3 (en) 1997-08-06
AU2576795A (en) 1996-01-05
NZ287139A (en) 1997-07-27
ES2163512T3 (es) 2002-02-01
HUT75777A (en) 1997-05-28
CN1158614A (zh) 1997-09-03
KR100350921B1 (ko) 2002-11-18
FI965020A0 (fi) 1996-12-13
WO1995034559A1 (fr) 1995-12-21
SI0787726T1 (en) 2002-04-30
PL181867B1 (pl) 2001-09-28
FI112485B (fi) 2003-12-15
HU220072B (hu) 2001-10-28
HU9603455D0 (en) 1997-02-28
CA2192824C (en) 2006-11-07
CA2192824A1 (en) 1995-12-21
PT787726E (pt) 2002-04-29
PL317726A1 (en) 1997-04-28
MX9606331A (es) 1997-03-29
FI965020A (fi) 1996-12-16
EP0787726A1 (en) 1997-08-06
DE69524251D1 (de) 2002-01-10
JP3391796B2 (ja) 2003-03-31
BR9508037A (pt) 1997-09-16
US5817669A (en) 1998-10-06
CZ364396A3 (en) 1997-06-11
HK1000495A1 (en) 2002-07-19
NO307255B1 (no) 2000-03-06
CZ292631B6 (cs) 2003-11-12
NO965305L (no) 1997-02-04
ATE209645T1 (de) 2001-12-15

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Legal Events

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MK1K Patent expired