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NO961067L - Subtilisin BPN' varianter med senket adsorpsjon og öket hydrolyse - Google Patents

Subtilisin BPN' varianter med senket adsorpsjon og öket hydrolyse

Info

Publication number
NO961067L
NO961067L NO961067A NO961067A NO961067L NO 961067 L NO961067 L NO 961067L NO 961067 A NO961067 A NO 961067A NO 961067 A NO961067 A NO 961067A NO 961067 L NO961067 L NO 961067L
Authority
NO
Norway
Prior art keywords
subtilisin bpn
variants
increased hydrolysis
decreased adsorption
bpn
Prior art date
Application number
NO961067A
Other languages
English (en)
Other versions
NO961067D0 (no
Inventor
Iii Philip Frederick Brode
Bobby Lee Barnett
Donn Nelton Rubingh
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of NO961067D0 publication Critical patent/NO961067D0/no
Publication of NO961067L publication Critical patent/NO961067L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38609—Protease or amylase in solid compositions only

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Detergent Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Det er beskrevet subtilisin BPN' varianter omfat- tende minst en eller flere aminosyreposisjoner som har en forskjellig aminosyre enn den som opptrer i villtype subtilisin BPN' {dvs substitusjoner) ved posisjonene 199 - 220, hvorved BPN' varianten har minket adsorpsjon til, og øket hydrolyse av, et uoppløselig substrat sammenlignet med villtype subtilisin BPN'.
NO961067A 1993-09-15 1996-03-15 Subtilisin BPN' varianter med senket adsorpsjon og öket hydrolyse NO961067L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12143793A 1993-09-15 1993-09-15
US28746194A 1994-08-11 1994-08-11
PCT/US1994/010020 WO1995007991A2 (en) 1993-09-15 1994-08-31 Subtilisin bpn' variants with decreased adsorption and increased hydrolysis

Publications (2)

Publication Number Publication Date
NO961067D0 NO961067D0 (no) 1996-03-15
NO961067L true NO961067L (no) 1996-05-15

Family

ID=26819467

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961067A NO961067L (no) 1993-09-15 1996-03-15 Subtilisin BPN' varianter med senket adsorpsjon og öket hydrolyse

Country Status (14)

Country Link
EP (1) EP0719339B1 (no)
JP (1) JPH09502610A (no)
CN (1) CN1057123C (no)
AT (1) ATE343636T1 (no)
AU (1) AU7870394A (no)
BR (1) BR9407502A (no)
CA (1) CA2170491C (no)
CZ (1) CZ79196A3 (no)
DE (1) DE69434873T2 (no)
ES (1) ES2275265T3 (no)
HU (1) HUT74222A (no)
MA (1) MA23330A1 (no)
NO (1) NO961067L (no)
WO (1) WO1995007991A2 (no)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436690B1 (en) 1993-09-15 2002-08-20 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
US6440717B1 (en) 1993-09-15 2002-08-27 The Procter & Gamble Company BPN′ variants having decreased adsorption and increased hydrolysis
ZA952220B (en) * 1994-05-02 1995-12-14 Procter & Gamble Bpn' variants having decreased adsorption and increased hydrolysis wherein one or more loop regions are substituted
US6599730B1 (en) * 1994-05-02 2003-07-29 Procter & Gamble Company Subtilisin 309 variants having decreased adsorption and increased hydrolysis
US6455295B1 (en) 1995-03-08 2002-09-24 The Procter & Gamble Company Subtilisin Carlsberg variants having decreased adsorption and increased hydrolysis
IL117352A0 (en) * 1995-03-09 1996-07-23 Procter & Gamble Thermitase variants having decreased adsorption and increased hydrolysis
IL117350A0 (en) 1995-03-09 1996-07-23 Procter & Gamble Proteinase k variants having decreased adsorption and increased hydrolysis
US6475765B1 (en) 1995-03-09 2002-11-05 Procter & Gamble Company Subtilisin DY variants having decreased adsorption and increased hydrolysis
US5718895A (en) * 1995-11-16 1998-02-17 Alcon Laboratories, Inc. Enzymes with low isoelectric points for use in contact lens cleaning
DE19617229A1 (de) * 1996-04-30 1997-11-06 Basf Ag Verfahren zur Herstellung von niedermolekularen Ethylenpolymerisaten im Hochdruck
AU2742499A (en) 1998-03-26 1999-10-18 Procter & Gamble Company, The Serine protease variants having amino acid substitutions
US6908757B1 (en) 1998-03-26 2005-06-21 The Procter & Gamble Company Serine protease variants having amino acid deletions and substitutions
AU6085800A (en) 1999-07-22 2001-02-13 Procter & Gamble Company, The Subtilisin protease variants having amino acid substitutions in defined epitope regions
CN1373802A (zh) 1999-07-22 2002-10-09 宝洁公司 在特定表位区域具有氨基酸缺失和取代的枯草杆菌蛋白酶变体
US6946128B1 (en) 1999-07-22 2005-09-20 The Procter & Gamble Company Protease conjugates having sterically protected epitope regions
CA2379729A1 (en) 1999-07-22 2001-02-01 The Procter & Gamble Company Protease conjugates having sterically protected clip sites
AU5911599A (en) * 1999-09-09 2001-04-10 Procter & Gamble Company, The A detergent composition containing a protease
US20050101012A1 (en) 2001-03-12 2005-05-12 Gerold Schuler CD4+CD25+ regulatory T cells from human blood
DE10153792A1 (de) * 2001-10-31 2003-05-22 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
EP1321513A1 (en) * 2001-12-21 2003-06-25 Direvo Biotech AG Subtilisin variants with improved characteristics
US8222033B2 (en) 2002-08-12 2012-07-17 Argos Therapeutics, Inc. CD4+CD25− T cells and Tr1-like regulatory T cells
JP5639324B2 (ja) * 2003-08-06 2014-12-10 ユニバーシティー オブ メリーランド，カレッジ パーク 融合タンパク質のアフィニティ精製およびプロセッシングのための修飾されたプロテアーゼ
EP2171055B1 (en) 2007-06-06 2016-03-16 Danisco US Inc. Methods for improving multiple protein properties
DE102007044415A1 (de) 2007-09-17 2009-03-19 Henkel Ag & Co. Kgaa Leistungsverbesserte Proteasen und Wasch- und Reinigungsmittel enthaltend diese Proteasen
JP2011524166A (ja) * 2008-06-06 2011-09-01 ダニスコ・ユーエス・インク 変異体微生物プロテアーゼを含む組成物及び方法
EP2166076A1 (en) 2008-09-23 2010-03-24 The Procter & Gamble Company Cleaning composition
EP2362896A2 (en) * 2008-11-11 2011-09-07 Danisco US Inc. Bacillus subtilisin comprising one or more combinable mutations
EP2814956B1 (en) * 2012-02-17 2017-05-10 Novozymes A/S Subtilisin variants and polynucleotides encoding same
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4990452A (en) * 1986-02-12 1991-02-05 Genex Corporation Combining mutations for stabilization of subtilisin
ES2227508T3 (es) * 1989-06-26 2005-04-01 Unilever N.V. Composiciones detergentes enzimaticas.
DK0563169T3 (da) * 1990-12-21 1998-05-18 Novo Nordisk As Enzymmutanter med lille variation i molekylær ladning i et pH område

Also Published As

Publication number Publication date
CA2170491C (en) 2001-10-30
HUT74222A (en) 1996-11-28
BR9407502A (pt) 1997-01-07
ATE343636T1 (de) 2006-11-15
JPH09502610A (ja) 1997-03-18
CN1057123C (zh) 2000-10-04
DE69434873T2 (de) 2007-09-06
CN1134728A (zh) 1996-10-30
MA23330A1 (fr) 1995-04-01
ES2275265T3 (es) 2007-06-01
WO1995007991A2 (en) 1995-03-23
WO1995007991A3 (en) 1995-04-13
EP0719339A1 (en) 1996-07-03
HU9600667D0 (en) 1996-05-28
CA2170491A1 (en) 1995-03-23
DE69434873D1 (de) 2006-12-07
CZ79196A3 (en) 1996-06-12
AU7870394A (en) 1995-04-03
NO961067D0 (no) 1996-03-15
EP0719339B1 (en) 2006-10-25

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FC2A Withdrawal, rejection or dismissal of laid open patent application