[go: up one dir, main page]

NO953638L - Gas-generating contrast agents - Google Patents

Gas-generating contrast agents

Info

Publication number
NO953638L
NO953638L NO953638A NO953638A NO953638L NO 953638 L NO953638 L NO 953638L NO 953638 A NO953638 A NO 953638A NO 953638 A NO953638 A NO 953638A NO 953638 L NO953638 L NO 953638L
Authority
NO
Norway
Prior art keywords
contrast agents
gas
generating contrast
generating
formulation
Prior art date
Application number
NO953638A
Other languages
Norwegian (no)
Other versions
NO953638D0 (en
Inventor
Arne Aabye
Arne Berg
Harald Dugstad
Kari Dyvik
Per A Foss
Jo Klaveness
Jonny Oestensen
Paal Rongved
Per Strande
Helge Tolleshaug
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of NO953638L publication Critical patent/NO953638L/en
Publication of NO953638D0 publication Critical patent/NO953638D0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/227—Liposomes, lipoprotein vesicles, e.g. LDL or HDL lipoproteins, micelles, e.g. phospholipidic or polymeric
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)

Abstract

Mikropartikulære materialer som kjemisk kan danne gass etter formulering med en passende bærervæske, f.eks. vann for injeksjon, og/eller etter administrering f.eks. som resultat av kontakt med blod eller andre kroppsvæsker, kan brukes som kontrastmidler i diagnostisk avbilding, spesielt ultralyd og magnetisk resonansavbilding.Microparticulate materials which can chemically form gas after formulation with a suitable carrier liquid, e.g. water for injection, and / or after administration e.g. as a result of contact with blood or other bodily fluids, can be used as contrast agents in diagnostic imaging, especially ultrasound and magnetic resonance imaging.

NO953638A 1993-03-16 1995-09-15 Gas-generating contrast agents NO953638D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939305351A GB9305351D0 (en) 1993-03-16 1993-03-16 Improvements in or relating to contrast agents
PCT/GB1994/000522 WO1994021302A1 (en) 1993-03-16 1994-03-16 Improvements in or relating to contrast agents

Publications (2)

Publication Number Publication Date
NO953638L true NO953638L (en) 1995-09-15
NO953638D0 NO953638D0 (en) 1995-09-15

Family

ID=10732118

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953638A NO953638D0 (en) 1993-03-16 1995-09-15 Gas-generating contrast agents

Country Status (15)

Country Link
EP (1) EP0689462A1 (en)
JP (1) JPH08507781A (en)
KR (1) KR960700760A (en)
CN (1) CN1121314A (en)
AU (1) AU695529B2 (en)
BR (1) BR9406199A (en)
CA (1) CA2158359A1 (en)
CZ (1) CZ237195A3 (en)
FI (1) FI954326A (en)
GB (1) GB9305351D0 (en)
HU (1) HUT72984A (en)
NO (1) NO953638D0 (en)
PL (1) PL310657A1 (en)
SK (1) SK113795A3 (en)
WO (1) WO1994021302A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9106673D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
US5333613A (en) * 1993-03-23 1994-08-02 Delineate Microparticles as ultrasonic contrast media
US5897851A (en) * 1995-06-07 1999-04-27 Sonus Pharmaceuticals, Inc. Nucleation and activation of a liquid-in-liquid emulsion for use in ultrasound imaging
GB9511488D0 (en) * 1995-06-07 1995-08-02 Nycomed Imaging As Improvements in or relating to contrast agents
GB9622711D0 (en) * 1996-10-31 1997-01-08 British Tech Group Instrument having enhanced ultrasound visibility
US6278893B1 (en) * 1998-01-05 2001-08-21 Nycomed Imaging As Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
US20070110674A1 (en) * 2005-07-29 2007-05-17 Yuhong Xu Sono-active liposomes and lipid particles and use thereof as contrast agents and active-agent delivery systems
EP4154915A1 (en) 2014-12-31 2023-03-29 Lantheus Medical Imaging, Inc. Lipid-encapsulated gas microsphere compositions and related methods
JP2019515936A (en) 2016-05-04 2019-06-13 ランセウス メディカル イメージング， インコーポレイテッド Methods and devices for preparing ultrasound contrast agents
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
GB201821049D0 (en) * 2018-12-21 2019-02-06 Ge Healthcare As Ultrasound contrast agent and methods for use therof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900540A (en) * 1983-06-20 1990-02-13 Trustees Of The University Of Massachusetts Lipisomes containing gas for ultrasound detection
US4684479A (en) * 1985-08-14 1987-08-04 Arrigo Joseph S D Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures
JPH0678247B2 (en) * 1988-10-04 1994-10-05 大塚製薬株式会社 Iron-containing preparation for NMR contrast
US5147631A (en) * 1991-04-30 1992-09-15 Du Pont Merck Pharmaceutical Company Porous inorganic ultrasound contrast agents
WO1993017718A1 (en) * 1992-03-06 1993-09-16 Nycomed Imaging A/S Improvements in or relating to contrast agents

Also Published As

Publication number Publication date
CN1121314A (en) 1996-04-24
AU695529B2 (en) 1998-08-13
FI954326A0 (en) 1995-09-14
CA2158359A1 (en) 1994-09-29
GB9305351D0 (en) 1993-05-05
JPH08507781A (en) 1996-08-20
FI954326A (en) 1995-10-11
SK113795A3 (en) 1997-02-05
EP0689462A1 (en) 1996-01-03
HUT72984A (en) 1996-06-28
HU9502693D0 (en) 1995-11-28
CZ237195A3 (en) 1996-05-15
BR9406199A (en) 1995-12-12
AU6215394A (en) 1994-10-11
KR960700760A (en) 1996-02-24
WO1994021302A1 (en) 1994-09-29
PL310657A1 (en) 1995-12-27
NO953638D0 (en) 1995-09-15

Similar Documents

Publication Publication Date Title
NO953638L (en) Gas-generating contrast agents
DK0458745T4 (en) Gas or air filled polymer microballoons which can be used as suspensions in liquid carriers for ultrasonic echography
ATE246902T1 (en) CONTROLLING CONTRAST-ENHANCED IMAGING
ES2149264T3 (en) THERAPEUTIC AGENT FOR THE TREATMENT OF MELANOMAS.
FI972628A (en) New sulfonamides
IL133265A0 (en) Heparanase specific molecular probes and their use in research and medical applications
ATE78175T1 (en) MAGNETIC LIQUID COMPOSITIONS.
MX9102814A (en) ADMINISTRATION FORM FOR ECO-CONTRASTING AGENTS IN MICROBUBBLES.
ES2053325T3 (en) INSTRUMENT FOR PERFORMING MEDICAL OR SURGICAL INTERVENTIONS BY LAPAROSCOPY OR COELIOSCOPY.
ATE254953T1 (en) SURFACE MODIFIED, BIOCOMPATIBLE MEMBRANES
FI941242A0 (en) Gaseous ultrasound contrast agent and method for selecting gases for use as ultrasonic contrast agent
GB9203037D0 (en) Contrast agents
ATE438407T1 (en) DIAGNOSIS, PREVENTION AND TREATMENT OF ULCERATIVE COLITIS AND ITS SUBTYPES USING MICROBIAL UC PANCA ANTIGENS
NO955351L (en) Protein-encapsulated, insoluble gas microspheres, their preparation and use as ultrasonic contrast agent
DK1107804T3 (en) Syringes and injectors provided with magnetic fluid actuators
BG51046A3 (en) Method for the preparation of pyrido (1, 2- a) pyrazine derivatives
AR020071A1 (en) ANTIBODIES THAT HAVE AN OPTIMIZED AFFINITY FOR A CHARACTERISTIC EPITOPE OF ED-B DOMAIN OF FIBRONECTINE, CONJUGATES CONTAINING THOSE ANTIBODIES AND THERAPEUTIC METHODS FOR THE TREATMENT OF ANGIOGENESIS.
ATE142113T1 (en) CATHETER FOR INSERTION THROUGH A NEEDLE
AU607461B2 (en) Sterilization of compositions of limited stability
SE0202172D0 (en) Device and method for circulatory isolation and treatment of a part of a body
YU47856B (en) BATHROOMS AND PROCEDURE FOR CHEMICAL POLISHING OF STAINLESS STEEL SURFACES
DE3160530D1 (en) Agent for detecting peroxidatively active substances and use of polyvinylmethyl-acyl amide in the same
ATE89563T1 (en) OXIRAN-PSEUDOOLIGOSACCHARIDES, PROCESSES FOR THEIR PRODUCTION, THEIR USE AND PHARMACEUTICAL PREPARATIONS.
Cheng The surgery of mitral stenosis 1898-1948: why did it take 50 years to establish mitral valvotomy?
Cyriax Diseases of Joints