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NO944749L - Nye steroider med pregnanskjelett, farmasöytiske preparater inneholdende disse, og fremgangsmåte for fremtilling av disse - Google Patents

Nye steroider med pregnanskjelett, farmasöytiske preparater inneholdende disse, og fremgangsmåte for fremtilling av disse

Info

Publication number
NO944749L
NO944749L NO944749A NO944749A NO944749L NO 944749 L NO944749 L NO 944749L NO 944749 A NO944749 A NO 944749A NO 944749 A NO944749 A NO 944749A NO 944749 L NO944749 L NO 944749L
Authority
NO
Norway
Prior art keywords
amino group
heterocyclic secondary
secondary amino
alkyl
carbon atoms
Prior art date
Application number
NO944749A
Other languages
English (en)
Norwegian (no)
Other versions
NO944749D0 (no
Inventor
Sandor Maho
Zoltan Tuba
Aniko Gere
Pal Vittay
Bela Kiss
Eva Palosi
Laszlo Szporny
Erzsebet Francsicsne Czinege
Anna Mezei Boorne
Gabor Balogh
Sandor Gorog
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of NO944749D0 publication Critical patent/NO944749D0/no
Publication of NO944749L publication Critical patent/NO944749L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/50—Three nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
NO944749A 1992-06-09 1994-12-08 Nye steroider med pregnanskjelett, farmasöytiske preparater inneholdende disse, og fremgangsmåte for fremtilling av disse NO944749L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU9201910A HU212308B (en) 1992-06-09 1992-06-09 Process for producing novel pregnane steroids and pharmaceutical compositions containing the same
PCT/HU1993/000035 WO1993025570A1 (en) 1992-06-09 1993-06-08 Novel steroids with pregnane skeleton, pharmaceutical compositions containing them and process for preparing same

Publications (2)

Publication Number Publication Date
NO944749D0 NO944749D0 (no) 1994-12-08
NO944749L true NO944749L (no) 1995-02-08

Family

ID=10982020

Family Applications (1)

Application Number Title Priority Date Filing Date
NO944749A NO944749L (no) 1992-06-09 1994-12-08 Nye steroider med pregnanskjelett, farmasöytiske preparater inneholdende disse, og fremgangsmåte for fremtilling av disse

Country Status (17)

Country Link
US (1) US5547949A (fi)
EP (1) EP0646126A1 (fi)
JP (1) JPH07507792A (fi)
KR (1) KR950701933A (fi)
AU (1) AU4352393A (fi)
CA (1) CA2136546A1 (fi)
CZ (1) CZ308094A3 (fi)
EE (1) EE9400071A (fi)
FI (1) FI945781A (fi)
HR (1) HRP930956A2 (fi)
HU (1) HU212308B (fi)
IL (1) IL105943A0 (fi)
NO (1) NO944749L (fi)
RU (1) RU94046369A (fi)
SI (1) SI9300311A (fi)
WO (1) WO1993025570A1 (fi)
ZA (1) ZA934036B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69942578D1 (de) 1998-05-22 2010-08-26 Univ R Bifunktionelle moleküle sowie darauf basierende therapien.
US20040127502A1 (en) * 2001-01-31 2004-07-01 Synaptic Pharmaceutical Corporation Use of GAL3 antagonist for treatment of depression
US7081470B2 (en) * 2001-01-31 2006-07-25 H. Lundbeck A/S Use of GALR3 receptor antagonists for the treatment of depression and/or anxiety and compounds useful in such methods
MY141867A (en) * 2002-06-20 2010-07-16 Vertex Pharma Substituted pyrimidines useful as protein kinase inhibitors
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
NL2000323C2 (nl) * 2005-12-20 2007-11-20 Pfizer Ltd Pyrimidine-derivaten.
EP2805720B1 (en) 2008-05-28 2019-08-07 ReveraGen BioPharma, Inc. Non-hormonal steroid modulators of NF-KB for treatment of disease
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
MY163048A (en) 2009-05-06 2017-08-15 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
EP2556083A4 (en) 2010-04-05 2013-12-04 Validus Biopharma Inc NONHORMONAL STEROID MODULATORS OF NF-KAPPA-B FOR DISEASE TREATMENT
WO2017004205A1 (en) 2015-06-29 2017-01-05 Reveragen Biopharma, Inc. NON-HORMONAL STEROID MODULATORS OF NF-κB FOR TREATMENT OF DISEASE
US11382922B2 (en) 2019-03-07 2022-07-12 Reveragen Biopharma, Inc. Aqueous oral pharmaceutical suspension compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5099019A (en) * 1985-09-12 1992-03-24 Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
ES2078890T3 (es) * 1986-10-09 1996-01-01 Upjohn Co Amino esteroides en c20 a c26.
FR2644789B1 (fr) * 1989-03-22 1995-02-03 Roussel Uclaf Nouveaux steroides 19-nor, 3-ceto comportant une chaine en 17 aminosubstituee, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2644787B1 (fr) * 1989-03-22 1995-02-03 Roussel Uclaf Nouveaux steroides 21 aminosubstitues, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
CA2071000A1 (en) * 1990-01-26 1991-07-27 John M. Mccall 5-oxygenated-2,4,6-triaminopyrimidines

Also Published As

Publication number Publication date
KR950701933A (ko) 1995-05-17
SI9300311A (sl) 1993-12-31
HUT64562A (en) 1994-01-28
EE9400071A (et) 1995-12-15
HU9201910D0 (en) 1992-09-28
FI945781A0 (fi) 1994-12-08
ZA934036B (en) 1994-01-06
IL105943A0 (en) 1993-10-20
AU4352393A (en) 1994-01-04
JPH07507792A (ja) 1995-08-31
HU212308B (en) 1996-05-28
EP0646126A1 (en) 1995-04-05
WO1993025570A1 (en) 1993-12-23
HRP930956A2 (hr) 1995-02-28
FI945781A (fi) 1994-12-08
RU94046369A (ru) 1996-09-27
NO944749D0 (no) 1994-12-08
CZ308094A3 (en) 1995-11-15
US5547949A (en) 1996-08-20
CA2136546A1 (en) 1993-12-23

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