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NO942835D0 - 1-benzensulfonyl-1,3-dihydro-2H-benzimidazol-2-on-derivater, fremstilling derav og farmasöytiske blandinger som inneholder dem - Google Patents

1-benzensulfonyl-1,3-dihydro-2H-benzimidazol-2-on-derivater, fremstilling derav og farmasöytiske blandinger som inneholder dem

Info

Publication number
NO942835D0
NO942835D0 NO942835A NO942835A NO942835D0 NO 942835 D0 NO942835 D0 NO 942835D0 NO 942835 A NO942835 A NO 942835A NO 942835 A NO942835 A NO 942835A NO 942835 D0 NO942835 D0 NO 942835D0
Authority
NO
Norway
Prior art keywords
benzimidazol
benzenesulfonyl
dihydro
derivatives
preparation
Prior art date
Application number
NO942835A
Other languages
English (en)
Other versions
NO942835L (no
NO304374B1 (no
Inventor
Alain Di Malta
Georges Garcia
Daniel Mettefeu
Dino Nisato
Richard Roux
Claudine Serradeil-Legal
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of NO942835D0 publication Critical patent/NO942835D0/no
Publication of NO942835L publication Critical patent/NO942835L/no
Publication of NO304374B1 publication Critical patent/NO304374B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/22Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms directly attached to ring nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO942835A 1993-07-30 1994-07-29 1-benzensulfonyl-1,3-dihydro-2H-benzimidazol-2-on-derivater, og farmas°ytiske blandinger som inneholder dem NO304374B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9309403A FR2708608B1 (fr) 1993-07-30 1993-07-30 Dérivés de N-sulfonylbenzimidazolone, leur préparation, les compositions pharmaceutiques en contenant.

Publications (3)

Publication Number Publication Date
NO942835D0 true NO942835D0 (no) 1994-07-29
NO942835L NO942835L (no) 1995-01-31
NO304374B1 NO304374B1 (no) 1998-12-07

Family

ID=9449793

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942835A NO304374B1 (no) 1993-07-30 1994-07-29 1-benzensulfonyl-1,3-dihydro-2H-benzimidazol-2-on-derivater, og farmas°ytiske blandinger som inneholder dem

Country Status (16)

Country Link
US (1) US5585394A (no)
EP (1) EP0636614A1 (no)
JP (1) JPH07215947A (no)
KR (1) KR950003275A (no)
CN (1) CN1106804A (no)
AU (1) AU679535B2 (no)
CA (1) CA2129214A1 (no)
FI (1) FI943571A (no)
FR (1) FR2708608B1 (no)
HU (1) HUT67801A (no)
IL (1) IL110481A0 (no)
NO (1) NO304374B1 (no)
NZ (1) NZ264119A (no)
RU (1) RU2135477C1 (no)
TW (1) TW368500B (no)
ZA (1) ZA945655B (no)

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US5728712A (en) * 1995-05-19 1998-03-17 Chiroscience Limited 3,4-disubstituted-phenylsulphonamides and their therapeutic use
US5756497A (en) * 1996-03-01 1998-05-26 Merck & Co., Inc. Tocolytic oxytocin receptor antagonists
AU2388697A (en) 1996-04-19 1997-11-12 Neurosearch A/S 1-(4-piperidyl)-benzimidazoles having neurotrophic activity
DE19929076A1 (de) * 1999-06-25 2000-12-28 Aventis Pharma Gmbh Indanylsubstituierte Benzolcarbonamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
JP4710140B2 (ja) * 2000-01-20 2011-06-29 東レ・ファインケミカル株式会社 ピロリン誘導体の製造法
US20040006142A1 (en) * 2000-05-03 2004-01-08 Ryuji Ueno Ocular tension depressor
US6653478B2 (en) 2000-10-27 2003-11-25 Ortho-Mcneil Pharmaceutical, Inc. Substituted benzimidazol-2-ones as vasopressin receptor antagonists and neuropeptide Y modulators
EP1379246B1 (en) * 2001-04-18 2008-10-08 Euro-Celtique S.A. Nociceptin analogs
CA2532076A1 (en) * 2003-07-23 2005-02-03 Wyeth Sulfonyldihydroimid- azopyridinone compounds as 5-hydroxytryptamine-6 ligands
AU2004259739A1 (en) * 2003-07-23 2005-02-03 Wyeth Sulfonyldihydro- benzimidazolone compounds as 5-hydroxytryptamine-6 ligands
ES2282062T1 (es) 2004-06-04 2007-10-16 Teva Pharmaceutical Industries Ltd. Composicion farmaceutica que contiene irbesartan.
JP2008515956A (ja) * 2004-10-12 2008-05-15 ノボ ノルディスク アクティーゼルスカブ 11β−ヒドロキシステロイドデヒドロゲナーゼ1型活性スピロ化合物
JP2009513611A (ja) * 2005-11-01 2009-04-02 ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー 置換アミドの医薬用途
JP2009514818A (ja) * 2005-11-01 2009-04-09 ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー 置換アミドの製薬学的用途
US20100168083A1 (en) * 2006-03-21 2010-07-01 Soren Ebdrup Adamantane derivatives for the treatment of the metabolic syndrome
CN101448782A (zh) 2006-04-07 2009-06-03 高点制药有限责任公司 对1型11β-羟基甾体脱氢酶具有活性的化合物
DE102006024024A1 (de) * 2006-05-23 2007-11-29 Bayer Healthcare Aktiengesellschaft Substituierte Arylimidazolone und -triazolone sowie ihre Verwendung
WO2007144394A2 (en) * 2006-06-16 2007-12-21 High Point Pharmaceuticals, Llc. Pharmaceutical use of substituted piperidine carboxamides
EP1878721A1 (en) * 2006-07-13 2008-01-16 Novo Nordisk A/S 4-Piperidylbenzamides as 11-beta-hydroxysteroid dehydrogenase type 1 inhibitors
CA2657078A1 (en) * 2006-07-13 2008-01-17 High Point Pharmaceuticals, Llc 11beta-hydroxysteroid dehydrogenase type 1 active compounds
JP5437070B2 (ja) * 2006-08-26 2014-03-12 アボット ゲーエムベーハー ウント カンパニー カーゲー 置換ベンゾイミダゾロン誘導体、それを含む薬剤およびそれの使用
ZA200904916B (en) * 2007-02-23 2010-09-29 High Point Pharmaceuticals Llc N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
JP2010519240A (ja) * 2007-02-23 2010-06-03 ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー 11−ベータ−ヒドロキシステロイドデヒドロゲナーゼの阻害剤としての、n−アダマンチルベンズアミド
EP2146952A1 (en) * 2007-02-23 2010-01-27 High Point Pharmaceuticals, LLC N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
JP2010519242A (ja) 2007-02-23 2010-06-03 ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー 新規化合物
JP2010520864A (ja) * 2007-03-09 2010-06-17 ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー ヒドロキシステロイドデヒドロゲナーゼインヒビターとしてのインドール−及びベンズイミダゾールアミド類
EP2152081B1 (en) * 2007-04-11 2012-10-24 High Point Pharmaceuticals, LLC Novel compounds
EP2150109B1 (en) * 2007-04-24 2012-09-19 High Point Pharmaceuticals, LLC Pharmaceutical use of substituted amides
BRPI0921299A2 (pt) * 2008-11-21 2015-08-25 High Point Pharmaceuticals Llc Compostos de benzamida adamantila
DE102008060967A1 (de) 2008-12-06 2010-06-10 Bayer Schering Pharma Aktiengesellschaft Substituierte Phenylsulfonyltriazolone und ihre Verwendung
DE102010001064A1 (de) * 2009-03-18 2010-09-23 Bayer Schering Pharma Aktiengesellschaft Substituierte 2-Acetamido-5-Aryl-1,2,4-triazolone und deren Verwendung
RS56312B1 (sr) 2010-02-27 2017-12-29 Bayer Ip Gmbh Ariltriazoloni spojeni sa bis-arilom i njihova upotreba
DE102010040187A1 (de) 2010-09-02 2012-03-08 Bayer Schering Pharma Aktiengesellschaft Substituierte N-Phenethyl-triazolonacetamide und ihre Verwendung
DE102010040924A1 (de) 2010-09-16 2012-03-22 Bayer Schering Pharma Aktiengesellschaft Substituierte Phenylacet- und Phenylpropanamide und ihre Verwendung
MA40893B1 (fr) 2014-11-03 2018-11-30 Bayer Pharma AG Dérivés de phényltriazole à substitution hydroxyalkyle et utilisations associées
US9988367B2 (en) 2016-05-03 2018-06-05 Bayer Pharma Aktiengesellschaft Amide-substituted pyridinyltriazole derivatives and uses thereof
WO2024050312A2 (en) * 2022-08-29 2024-03-07 The Broad Institute, Inc. T-type voltage-gated calcium channel potentiators

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US3405136A (en) * 1964-09-15 1968-10-08 Upjohn Co 1-phenylsulfonyl-2-benzimidazo-linones and 1-phenylsulfonyl-2-benzimidazolinethiones
BE792402A (fr) * 1971-12-07 1973-06-07 Ciba Geigy Composes heterocycliques azotes et medicaments anthelminthiqueset antimicrobiens qui en contiennent
CH634307A5 (de) * 1977-04-12 1983-01-31 Ciba Geigy Ag Anthelmintisch wirkende benzimidazolderivate, verfahren zu ihrer herstellung und mittel enthaltend diese wirkstoffe.
HU207051B (en) * 1987-12-30 1993-03-01 Chinoin Gyogyszer Es Vegyeszet Process for producing 4-chloro-3-sulfamoylbenzoic acid hydrazides and pharmaceutical compositions comprising such compounds
DE122009000062I2 (de) * 1989-10-20 2011-01-13 Otsuka Pharma Co Ltd Benzoheterozyklische verbindungen
FR2679903B1 (fr) * 1991-08-02 1993-12-03 Elf Sanofi Derives de la n-sulfonyl indoline portant une fonction amidique, leur preparation, les compositions pharmaceutiques en contenant.
US5338755A (en) * 1990-07-31 1994-08-16 Elf Sanofi N-sulfonylindoline derivatives, their preparation and the pharmaceutical compositions in which they are present
TW199153B (no) * 1990-08-07 1993-02-01 Dtsuka Seiyaku Kk
FR2686878B1 (fr) * 1992-01-30 1995-06-30 Sanofi Elf Derives du n-sulfonyl oxo-2 indole, leur preparation, les compositions pharmaceutiques en contenant.

Also Published As

Publication number Publication date
CN1106804A (zh) 1995-08-16
FI943571A0 (fi) 1994-07-29
AU6878894A (en) 1995-02-09
IL110481A0 (en) 1994-10-21
RU2135477C1 (ru) 1999-08-27
FI943571A (fi) 1995-01-31
KR950003275A (ko) 1995-02-16
HU9402238D0 (en) 1994-09-28
HUT67801A (en) 1995-05-29
NO942835L (no) 1995-01-31
TW368500B (en) 1999-09-01
AU679535B2 (en) 1997-07-03
FR2708608A1 (fr) 1995-02-10
ZA945655B (en) 1995-03-14
EP0636614A1 (fr) 1995-02-01
RU94027577A (ru) 1996-05-27
US5585394A (en) 1996-12-17
NZ264119A (en) 1996-02-27
JPH07215947A (ja) 1995-08-15
CA2129214A1 (en) 1995-01-31
FR2708608B1 (fr) 1995-10-27
NO304374B1 (no) 1998-12-07

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