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NO942749L - Water-soluble, non-immunogenic polyamide crosslinking agents - Google Patents

Water-soluble, non-immunogenic polyamide crosslinking agents

Info

Publication number
NO942749L
NO942749L NO942749A NO942749A NO942749L NO 942749 L NO942749 L NO 942749L NO 942749 A NO942749 A NO 942749A NO 942749 A NO942749 A NO 942749A NO 942749 L NO942749 L NO 942749L
Authority
NO
Norway
Prior art keywords
immunogenic
water
soluble
crosslinking agents
polyamide crosslinking
Prior art date
Application number
NO942749A
Other languages
Norwegian (no)
Other versions
NO942749D0 (en
Inventor
Ton T Hai
Deanna J Nelson
Original Assignee
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int filed Critical Baxter Int
Publication of NO942749D0 publication Critical patent/NO942749D0/en
Publication of NO942749L publication Critical patent/NO942749L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/26—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from polyamines and polycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polyamides (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

Foreliggende oppfinnelse vedrører også proteiner, polynukleotider og andre biologiske substrater som er kryss- bundet, konjugert, polymerisert eller dekorert med vannoppløselige poly- amider, hvorved det er dannet i det vesentlige ikke-immunogene produkter. DA-(BCDAB- PAS-MW (4) BCDAB - -CO-O^OCHj-CO-NH^^NH-CO-CHjOCHj-CO- (2o).(3o).(4<j):DA, - -HN-tCH^-OCHjC^O-CCH^j-NH- - -HN-(CH2)3-0(CH2CH^)2-(CH2)3-NH- Foreliggende oppfinnelse vedrører vannoppløselige, ikke-immunogene poly- amidkryssbindingsmidler og deres anvendelse til å kryssbinde, poly- merisere, dekorere og konjugere proteiner, polynukleotider og andre biologiske substrater, hvorved det dannes i det vesentlige ikke- immunogene, vannoppløselige produkter.The present invention also relates to proteins, polynucleotides and other biological substrates which are cross-linked, conjugated, polymerized or decorated with water-soluble polyamides, thereby forming substantially non-immunogenic products. DA- (BCDAB- PAS-MW (4) BCDAB - -CO-O ^ OCH 2 -CO-NH 4 NH-CO-CH 2 OCH 2 -CO- (2o). (3o). (4 <j): DA, - This invention relates to water-soluble, non-immunogenic polyamide crosslinking agents. and their use to cross-link, polymerize, decorate and conjugate proteins, polynucleotides and other biological substrates, thereby forming substantially non-immunogenic, water-soluble products.

NO942749A 1992-11-25 1994-07-22 Water-soluble, non-immunogenic polyamide crosslinking agents NO942749L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98144792A 1992-11-25 1992-11-25
PCT/US1993/011470 WO1994012220A2 (en) 1992-11-25 1993-11-24 Water soluble non-immunogenic polyamide cross-linking agents

Publications (2)

Publication Number Publication Date
NO942749D0 NO942749D0 (en) 1994-07-22
NO942749L true NO942749L (en) 1994-09-23

Family

ID=25528372

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942749A NO942749L (en) 1992-11-25 1994-07-22 Water-soluble, non-immunogenic polyamide crosslinking agents

Country Status (7)

Country Link
EP (1) EP0624099A1 (en)
JP (1) JPH07502784A (en)
AU (1) AU675686B2 (en)
CA (1) CA2135880A1 (en)
IL (1) IL107715A0 (en)
NO (1) NO942749L (en)
WO (1) WO1994012220A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10510822A (en) * 1994-12-21 1998-10-20 ノバルティス アクチェンゲゼルシャフト Oligonucleotide-dendrimer complex
EP1400551B1 (en) * 1998-08-28 2007-06-13 Amylin Pharmaceuticals, Inc. Polyamide chains of precise length and their conjugates with proteins
KR20010085742A (en) * 1998-08-28 2001-09-07 추후제출 Polyamide chains of precise length, methods to manufacture them and their conjugates with proteins
JP5503111B2 (en) * 2007-04-03 2014-05-28 ローム・アンド・ハース・エレクトロニック・マテリアルズ，エル．エル．シー． Metal plating composition and method

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53121899A (en) * 1977-04-01 1978-10-24 Sumitomo Chem Co Ltd Preparation of novel water-soluble polyamide
DE3307473A1 (en) * 1983-03-03 1984-09-06 Henkel KGaA, 4000 Düsseldorf MULTIFUNCTIONAL QUARTERS OF AMMONIUM COMPOUNDS WITH UP TO 4 QUARTERS OF AMMONIUM AT THE CHAIN END, THEIR PRODUCTION AND USE IN COSMETIC PREPARATIONS, IN PARTICULAR HAIR TREATMENT AGENTS
US4593073A (en) * 1985-04-23 1986-06-03 The Royal Institution For The Advancement Of Learing (Mcgill Univ.) Polymer resins with amino acid containing pendants for sorption of bile pigments and bile acids
EP0245840B1 (en) * 1986-05-15 1993-12-01 Hoechst Aktiengesellschaft Biodegradable polymers for retarding preparations with controlled release
CA1340387C (en) * 1987-10-30 1999-02-09 Carol A. Schlesinger Heterobifunctional coupling agents
CA1316858C (en) * 1988-06-10 1993-04-27 Keith E. Taylor Method and device for attachment of biologically useful materials to a solid phase
IT1244645B (en) * 1991-01-29 1994-08-08 Marco Castagneto DERIVATIVES OF DICARBOXYLIC ACIDS HAVING FROM SIX TO TWELVE CARBON ATOMS AND USE OF SUCH DERIVATIVES AND OF THE ACIDS ITSELF FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS SUITABLE FOR PARENTERAL ENTERAL FEEDING.

Also Published As

Publication number Publication date
CA2135880A1 (en) 1994-06-09
JPH07502784A (en) 1995-03-23
NO942749D0 (en) 1994-07-22
IL107715A0 (en) 1994-02-27
AU675686B2 (en) 1997-02-13
AU5729594A (en) 1994-06-22
WO1994012220A2 (en) 1994-06-09
WO1994012220A3 (en) 1994-09-29
EP0624099A1 (en) 1994-11-17

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