[go: up one dir, main page]

NO941676L - Polycykliske forbindelser og fremgangsmåter for fremstilling av dem - Google Patents

Polycykliske forbindelser og fremgangsmåter for fremstilling av dem

Info

Publication number
NO941676L
NO941676L NO941676A NO941676A NO941676L NO 941676 L NO941676 L NO 941676L NO 941676 A NO941676 A NO 941676A NO 941676 A NO941676 A NO 941676A NO 941676 L NO941676 L NO 941676L
Authority
NO
Norway
Prior art keywords
preparation
stands
hydrogen
processes
polycyclic compounds
Prior art date
Application number
NO941676A
Other languages
English (en)
Other versions
NO941676D0 (no
Inventor
Oskar Wacker
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO941676D0 publication Critical patent/NO941676D0/no
Publication of NO941676L publication Critical patent/NO941676L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Det blir beskrevet N-(tetrahydropyran-4-yloksy- alkanoyl)-staurosporinderlvater med formel I, H (D H,C hvor RI står for hydrogen, hydroksy, lavalkoksy eller okso, ~&2 står for hydrogen eller C1_4-alkyl og #3 står for hydrogen eller C1_4-alkyl, fremgangsmåter og nye mellomprodukter for deres fremstilling og anvendelse for fremstilling av mellomprodukter. Forbindelser med formel I hemmer med høy grad av selektivitet enzymet proteinkinase C, og kan spesielt bli anvendt som tumorhemmende virkestoff.
NO941676A 1993-05-07 1994-05-06 Polycykliske forbindelser og fremgangsmåter for fremstilling av dem NO941676L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH140693 1993-05-07
CH33594 1994-02-04

Publications (2)

Publication Number Publication Date
NO941676D0 NO941676D0 (no) 1994-05-06
NO941676L true NO941676L (no) 1994-11-08

Family

ID=25684254

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941676A NO941676L (no) 1993-05-07 1994-05-06 Polycykliske forbindelser og fremgangsmåter for fremstilling av dem

Country Status (14)

Country Link
US (2) US5382675A (no)
EP (1) EP0624590A1 (no)
JP (1) JPH06329678A (no)
CN (1) CN1097761A (no)
AU (1) AU680477B2 (no)
CA (1) CA2122960A1 (no)
CZ (1) CZ111894A3 (no)
FI (1) FI942046A (no)
HU (1) HUT70763A (no)
IL (1) IL109582A (no)
MA (1) MA23188A1 (no)
NO (1) NO941676L (no)
NZ (1) NZ260459A (no)
PH (1) PH30300A (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5624949A (en) * 1993-12-07 1997-04-29 Eli Lilly And Company Protein kinase C inhibitors
US5604219A (en) * 1994-03-18 1997-02-18 Kyowa Hakko Kogyo Co., Ltd. Indolocarbazole derivatives that stimulate platelet production
JPH10509708A (ja) * 1994-11-10 1998-09-22 コア セラピューティクス，インコーポレイティド プロテイン・キナーゼのインヒビターとして有用な医薬ピラゾール組成物
GB9610872D0 (en) * 1996-05-23 1996-07-31 Ciba Geigy Ag Protein kinase assay as a method for identification of fungicides
US6284783B1 (en) 1999-06-09 2001-09-04 The Uab Research Foundation Use of bisindolylmaleimide compounds to induce Fas-mediated apoptosis
AU6014900A (en) 1999-07-13 2001-01-30 Kyowa Hakko Kogyo Co. Ltd. Staurosporin derivatives
AU2004262927B2 (en) 2003-08-08 2008-05-22 Novartis Ag Combinations comprising staurosporines
CN111296417B (zh) * 2020-04-01 2021-04-20 广东省农业科学院植物保护研究所 一种星·甲维悬浮剂及其制备方法与应用
CN116041371B (zh) * 2023-01-29 2024-04-19 杭州科兴生物化工有限公司 7-羰基星孢菌素衍生物及其制备方法和应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4100178A (en) * 1976-04-14 1978-07-11 The Upjohn Company 4,5-Didehydro-6-methoxy-2-arylmethoxymethyl-4α-tetrahydropyranacetic acid alkyl esters
US4100177A (en) * 1976-04-14 1978-07-11 The Upjohn Company 4,5-Didehydro-6-hydroxy-2-arylmethoxymethyl-4α-tetrahydropyranacetic acid alkyl esters
US4359424A (en) * 1980-07-07 1982-11-16 Zoecon Corporation Substituted phenoxyethoxytetrahydropyran
US4304924A (en) * 1980-07-07 1981-12-08 Zoecon Corporation Cyclopropylmethyl benzoates
IL86632A0 (en) * 1987-06-15 1988-11-30 Ciba Geigy Ag Derivatives substituted at methyl-amino nitrogen
US5093330A (en) * 1987-06-15 1992-03-03 Ciba-Geigy Corporation Staurosporine derivatives substituted at methylamino nitrogen
EP0383919A4 (en) * 1988-02-04 1992-08-05 Kyowa Hakko Kogyo Co., Ltd. Staurosporin derivatives
DE3924538A1 (de) * 1989-07-25 1991-01-31 Goedecke Ag Indolocarbazol und dessen verwendung
AU7035991A (en) * 1989-12-14 1991-07-18 Schering Corporation Indolocarbazoles from saccharothrix aerocolonigenes subsp. copiosa subsp. nov. scc 1951 atcc 53856
GB9216298D0 (en) * 1991-08-15 1992-09-16 Ici Plc Piperidine derivatives
US5185260A (en) * 1991-08-29 1993-02-09 The United States Of America As Represented By The United States Department Of Energy Method for distinguishing normal and transformed cells using G1 kinase inhibitors
EP0541486A1 (de) * 1991-11-07 1993-05-12 Ciba-Geigy Ag Polycyclische Konjugate
EP0575955B1 (en) * 1992-06-22 1999-09-15 Kyowa Hakko Kogyo Co., Ltd. Process for producing staurosporine derivatives

Also Published As

Publication number Publication date
FI942046A (fi) 1994-11-08
AU680477B2 (en) 1997-07-31
MA23188A1 (fr) 1994-12-31
CA2122960A1 (en) 1994-11-08
CZ111894A3 (en) 1994-12-15
IL109582A0 (en) 1994-08-26
HU9401347D0 (en) 1994-08-29
CN1097761A (zh) 1995-01-25
PH30300A (en) 1997-01-20
AU6182894A (en) 1994-11-10
NZ260459A (en) 1995-12-21
HUT70763A (en) 1995-10-30
JPH06329678A (ja) 1994-11-29
US5455241A (en) 1995-10-03
NO941676D0 (no) 1994-05-06
IL109582A (en) 1997-09-30
FI942046A0 (fi) 1994-05-04
US5382675A (en) 1995-01-17
EP0624590A1 (de) 1994-11-17

Similar Documents

Publication Publication Date Title
CA2107105A1 (en) Heterocyclic-cyclic amine derivatives
CA2318145A1 (en) Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases
CA2165819A1 (en) Dc-89 derivatives
ATE211139T1 (de) Tetrahydroimidazopyridoindoldione als cgmp spezifische pde hemmer
DK0635498T3 (da) Quinazolinderivater og anvendelse deraf som anticancer-midler
DE69428025D1 (de) Proteinkinase C-Inhibitoren
ATE191218T1 (de) Rapamycin-derivate als immunosuppressoren
CA2197793A1 (en) New multimerizing agents
NO20030301L (no) Nye heteroarylderivater og anvendelse derav som farmasöytika
EP0555478A4 (en) Pyrimidine derivative and medicine
NO964095L (no) Nye hydroksypyridinoner
EE200200148A (et) Kinasoliini derivaadid, nende valmistamise meetodning kasutamine
WO2001032652A3 (en) N-substituted carbamoyloxyalkyl-azolium derivatives
CA2161542A1 (en) Novel 5-Pyrrolyl-2-Pyridylmethylsulfinyl Benzimidazole Derivatives
WO2001090071A3 (de) Substituierte iminoazine als herbizide
MX9702382A (es) Nuevos derivados de pirimidona con actividad antifungica.
NO941676L (no) Polycykliske forbindelser og fremgangsmåter for fremstilling av dem
DK0667856T3 (da) Nye D-vitaminanaloger
ATE104145T1 (de) 4-substituierten imidazolen zur senkung des intraokularen druckes.
WO2001023392A8 (en) Tetracyclic benzimidazole derivatives and combinatorial libraries thereof
CA2183050A1 (en) Sulfonyl- or sulfinylbenzoylguanidine derivatives
NZ527596A (en) Avermectins substituted in the 4"-position having pesticidal properties
NO20022123L (no) Osoksazolderivater for anvendelse som inhibitorer for fosfodiesterase VII
CA2182506A1 (en) 4-(alpha-methoxy)methylene-2h-chromene-3(4h)-one and its use in agriculture
ATE213241T1 (de) Amidin- und isothioharnstoffderivate als inhibitoren der stickstoffoxid-synthase