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NO940496L - Cykliske uretaner som er nyttige som antiarytmiske og antifibrillatoriske midler - Google Patents

Cykliske uretaner som er nyttige som antiarytmiske og antifibrillatoriske midler

Info

Publication number
NO940496L
NO940496L NO940496A NO940496A NO940496L NO 940496 L NO940496 L NO 940496L NO 940496 A NO940496 A NO 940496A NO 940496 A NO940496 A NO 940496A NO 940496 L NO940496 L NO 940496L
Authority
NO
Norway
Prior art keywords
antiarrhythmic
antifibrillatory agents
useful
cyclic urethanes
urethanes useful
Prior art date
Application number
NO940496A
Other languages
English (en)
Other versions
NO940496D0 (no
NO300807B1 (no
Inventor
Jr Stanford Salvatore Pelosi
Chia-Nien Yu
Original Assignee
Procter & Gamble Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble Pharma filed Critical Procter & Gamble Pharma
Publication of NO940496D0 publication Critical patent/NO940496D0/no
Publication of NO940496L publication Critical patent/NO940496L/no
Publication of NO300807B1 publication Critical patent/NO300807B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
NO940496A 1991-08-14 1994-02-14 Cykliske uretaner som er nyttige som antiarytmiske og antifibrillatoriske midler NO300807B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74486591A 1991-08-14 1991-08-14
PCT/US1992/006682 WO1993004064A1 (en) 1991-08-14 1992-08-10 Cyclic urethanes useful as antiarrhythmic and antifibrillatory agents

Publications (3)

Publication Number Publication Date
NO940496D0 NO940496D0 (no) 1994-02-14
NO940496L true NO940496L (no) 1994-02-14
NO300807B1 NO300807B1 (no) 1997-07-28

Family

ID=24994270

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940496A NO300807B1 (no) 1991-08-14 1994-02-14 Cykliske uretaner som er nyttige som antiarytmiske og antifibrillatoriske midler

Country Status (23)

Country Link
US (1) US5994354A (no)
EP (2) EP0599968B1 (no)
JP (1) JPH06510285A (no)
AT (1) ATE188696T1 (no)
AU (1) AU665367B2 (no)
BR (1) BR9206353A (no)
CA (1) CA2115029C (no)
CZ (1) CZ283323B6 (no)
DE (1) DE69230563T2 (no)
DK (1) DK0599968T3 (no)
ES (1) ES2141725T3 (no)
FI (1) FI940658A7 (no)
GR (1) GR3032432T3 (no)
HU (1) HUT70144A (no)
IL (1) IL102791A (no)
MX (1) MX9204736A (no)
NO (1) NO300807B1 (no)
NZ (1) NZ243936A (no)
PL (1) PL171280B1 (no)
PT (1) PT100775B (no)
RU (1) RU2125568C1 (no)
SK (1) SK16994A3 (no)
WO (1) WO1993004064A1 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL170961B1 (en) * 1991-08-14 1997-02-28 Procter & Gamble Pharma Method of obtaining novelurea derivatives useful as agents against arrythmia and fibrillation
CA2115426C (en) * 1991-08-14 2001-09-11 Stanford Salvatore Pelosi Jr. Novel cyclic ureas useful as antiarrhythmic and antifibrillatory agents
JPH06510285A (ja) * 1991-08-14 1994-11-17 プロクター、エンド、ギャンブル、ファーマスーティカルズ、インコーポレーテッド 抗不整脈及び抗細動剤として有用な環状ウレタン類
RU2194706C2 (ru) 1998-04-29 2002-12-20 Дзе Проктер Энд Гэмбл Компани Способ получения дигидрохлорида 1-[[[5-(4-хлорфенил)-2-фуранил]метилен]амино]-3-[4-(4-метил-1-пиперазинил) бутил]-2,4-имидазолидиндиона
TR200003136T2 (tr) 1998-04-29 2001-03-21 The Procter & Gamble Company 1,3-İki ikameli-4-oksosiklik ürelerin yapımı ile ilgili yöntem.
CN1171610C (zh) * 2002-04-23 2004-10-20 张瑞香 一种治疗心脑血管和眼底病的中药针剂及其制备方法
EP2205073A4 (en) * 2007-09-26 2013-03-06 Sinai School Medicine AZACYTIDINE ANALOGS AND USES THEREOF

Family Cites Families (44)

* Cited by examiner, † Cited by third party
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BE624402A (no) *
US2802002A (en) * 1956-07-18 1957-08-06 Norwich Pharma Co Series of new nu-(5-nitro-2-furyl) alkylidene-3-amino-5-tertiaryamino-methyl-2-oxazolidones and the preparation thereof
GB843834A (en) * 1957-05-13 1960-08-10 Norwich Pharma Co N-(5-nitro-2-furyl)-alkylidene-3-amino-5-tertiaryaminomethyl-2-oxazolidones and chemotherapeutic compositions containing them
FR1274399A (fr) * 1958-01-23 1961-10-27 Norwich Pharma Co Procédé perfectionné de préparation de dérivés du 5-nitro-2-formyl-furan
NL104211C (no) * 1958-02-28
US3004888A (en) * 1959-01-12 1961-10-17 Pfizer & Co C Mastitis treatment
NL266216A (no) * 1960-07-12
FR385M (fr) * 1960-08-17 1961-03-24 Norwich Pharma Co Nouveau médicament pour le traitement des infections staphylococciques et analogues.
CH398599A (fr) * 1961-03-24 1966-03-15 Om Lab Sa Procédé de préparation d'hydrazones de l'a-bromo-B-(5-nitro-2-furyl)acroléine
BE633841A (no) * 1962-06-21
NL120945C (no) * 1962-08-01
US3415821A (en) * 1965-09-07 1968-12-10 Norwich Pharma Co 1-(5-substituted)furfurylideneamino hydantoins and imidazolidinones
US3318878A (en) * 1966-04-14 1967-05-09 Smith Kline French Lab Nitrothiophene compounds
GB1279408A (en) * 1968-09-12 1972-06-28 Ciba Geigy Ag 5-nitro-2-furfurylideneamino-oxazolidinones
US3839567A (en) * 1969-04-17 1974-10-01 Schering Ag Pharmaceutical compositions comprising 3-(5-nitro-2-imidazolyl-methylen-amino)-2-oxazolidinones and their use in trichomoniasia
US3906101A (en) * 1969-06-05 1975-09-16 Ciba Geigy Corp Pharmaceutical compositions containing substituted 5-nitrofurfurylideneamino-oxazolidinones
US4775670A (en) * 1980-09-29 1988-10-04 E. R. Squibb & Sons, Inc. 2-oxo-1-azetidinesulfonic acid salts
US4393204A (en) * 1982-05-21 1983-07-12 Norwich Eaton Pharmaceuticals, Inc. 3-[[5-(4-Chlorophenyl)furfurylidene]amino]-5-(substituted)-2-oxazolidinones
US4466965A (en) * 1982-07-26 1984-08-21 American Hospital Supply Corporation Phthalazine compounds, compositions and use
US4543359A (en) * 1982-10-01 1985-09-24 Eaton Laboratories, Inc. Treating cardiac arrhythmias with dantrolene sodium
US4705799A (en) * 1983-06-07 1987-11-10 E. I. Du Pont De Nemours And Company Aminomethyl oxooxazolidinyl benzenes useful as antibacterial agents
US4581370A (en) * 1983-07-12 1986-04-08 Schering A.G. Antiarrhythmic imidazoliums
US4720580A (en) * 1984-09-21 1988-01-19 American Home Products Corporation N-(aminoalkylene)benzenesulfonamides
US4707499A (en) * 1985-12-02 1987-11-17 G. D. Searle & Co. 3-alkyl-5-(substituted amino)methyl)dihydro-3-phenyl-2(3H)-furanones and imino analogs thereof used for treatment of arrhythmia
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
US4713832A (en) * 1986-04-11 1987-12-15 Ampex Corporation Programmable divider up/down counter with anti-aliasing feature and asynchronous read/write
IL79174A0 (en) * 1986-06-05 1986-09-30 Abic Ltd Water soluble salt of furaltadone
US4895867A (en) * 1986-06-26 1990-01-23 Norwich Eaton Pharmaceuticals, Inc. 2-(5-phenyl-2-furanyl)imidazoles useful as cardiotonic agents
US4886794A (en) * 1987-05-07 1989-12-12 A. H. Robins Company, Incorporated 4-[(α,α-diaryl)-hydroxymethyl]-1-piperidinylalkyl-cyclic carbamate derivatives as allergic response inhibitors
AU607735B2 (en) * 1987-05-07 1991-03-14 A.H. Robins Company, Incorporated Novel cyclic carbamate derivatives
US4882354A (en) * 1987-12-16 1989-11-21 Norwich Eaton Pharmaceuticals, Inc. N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
US4870095A (en) * 1988-06-13 1989-09-26 Sterling Drug, Inc. 1H-pyrazole-1-alkanamides, antiarrhythmic compositions and use
JPH0276882A (ja) * 1988-06-20 1990-03-16 Eisai Co Ltd 光学活性ヒダントイン誘導体
US4948801A (en) * 1988-07-29 1990-08-14 E. I. Du Pont De Nemours And Company Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents
DE68918792T2 (de) * 1988-09-15 1995-03-30 Upjohn Co 5-Indolinyl-5-beta-amidomethyloxazolidin-2-one, 3-(substituierte kondensierte)phenyl-5-beta amidomethyloxazolidin-2-one und 3-(Nitrogen-substituierte)phenyl-5-beta-amidomethyloxazolidin-2-one.
PH30434A (en) * 1989-04-07 1997-05-09 Janssen Pharmaceutica Nv Hydroxyalkylfuranyl derivatives
US5091426A (en) * 1989-06-23 1992-02-25 Norwich Eaton Pharmaceuticals, Inc. 5-phenyl-2-furan ketones and use as antiepileptic agents
US4966967A (en) * 1989-09-15 1990-10-30 Berlex Laboratories, Inc. 3,4,5,6-tetrahydro-2H-1,7,4-benzodioxazonines as cardiovascular agents
US5032598A (en) * 1989-12-08 1991-07-16 Merck & Co., Inc. Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents
US4963561A (en) * 1990-02-28 1990-10-16 Sterling Drug Inc. Imidazopyridines, their preparation and use
US5066662A (en) * 1990-05-21 1991-11-19 Warner-Lambert Company Substituted oxazolidin-2-ones and 1,2,4-oxadiazolin-5-ones and derivatives thereof acting at muscarinic receptors
US5086055A (en) * 1990-12-24 1992-02-04 A. H. Robins Company, Incorporated Series of 5-[-(4-aryl-1-piperazinyl)alkyl]-2-oxazolidinone derivatives useful in the treatment of allergic conditions
FR2675504B1 (fr) * 1991-04-16 1995-01-27 Delalande Sa Derives d'aryl-3 oxazolidinone, leur procede de preparation et leur application en therapeutique.
JPH06510285A (ja) * 1991-08-14 1994-11-17 プロクター、エンド、ギャンブル、ファーマスーティカルズ、インコーポレーテッド 抗不整脈及び抗細動剤として有用な環状ウレタン類

Also Published As

Publication number Publication date
GR3032432T3 (en) 2000-05-31
EP0599968B1 (en) 2000-01-12
EP0599968A1 (en) 1994-06-08
DE69230563T2 (de) 2000-09-14
IL102791A (en) 1998-06-15
WO1993004064A1 (en) 1993-03-04
SK16994A3 (en) 1995-03-08
EP0957103A1 (en) 1999-11-17
CZ27894A3 (en) 1995-07-12
CA2115029A1 (en) 1993-03-04
BR9206353A (pt) 1995-11-07
HU9400403D0 (en) 1994-05-30
HUT70144A (en) 1995-09-28
PL171280B1 (pl) 1997-03-28
RU2125568C1 (ru) 1999-01-27
FI940658A0 (fi) 1994-02-11
AU665367B2 (en) 1996-01-04
JPH06510285A (ja) 1994-11-17
DK0599968T3 (da) 2000-04-17
US5994354A (en) 1999-11-30
ES2141725T3 (es) 2000-04-01
NZ243936A (en) 1996-10-28
AU2467892A (en) 1993-03-16
CZ283323B6 (cs) 1998-02-18
MX9204736A (es) 1993-11-01
ATE188696T1 (de) 2000-01-15
IL102791A0 (en) 1993-01-31
PT100775B (pt) 1999-09-30
PT100775A (pt) 1994-01-31
NO940496D0 (no) 1994-02-14
CA2115029C (en) 2002-03-26
DE69230563D1 (de) 2000-02-17
FI940658A7 (fi) 1994-02-11
NO300807B1 (no) 1997-07-28

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