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NO940080L - Polypeptider , fremgangsmåte for deres fremstilling og farmasöytiske preparater derav - Google Patents

Polypeptider , fremgangsmåte for deres fremstilling og farmasöytiske preparater derav

Info

Publication number
NO940080L
NO940080L NO940080A NO940080A NO940080L NO 940080 L NO940080 L NO 940080L NO 940080 A NO940080 A NO 940080A NO 940080 A NO940080 A NO 940080A NO 940080 L NO940080 L NO 940080L
Authority
NO
Norway
Prior art keywords
polypeptides
preparation
methods
pharmaceutical preparations
chelating group
Prior art date
Application number
NO940080A
Other languages
English (en)
Other versions
NO940080D0 (no
Inventor
Rainer Albert
Helmut Macke
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939300510A external-priority patent/GB9300510D0/en
Priority claimed from GB939313129A external-priority patent/GB9313129D0/en
Priority claimed from GB939315561A external-priority patent/GB9315561D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO940080D0 publication Critical patent/NO940080D0/no
Publication of NO940080L publication Critical patent/NO940080L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Oppfinnelsen omhandler somatostatinpeptider som bærer en chelaterende gruppe valgt fra en bi funksjonell N4-chelaterende gruppe som særlig er egnet for merking med Te, Rh, Cu, Co eller Re, og en bifunksjonell polyaminopolykarboksylsyre- chelaterende gruppe. Peptidene er kompleksdannet med et a-, P_; Y_ eller positronemitterende nuklid eller et nuklid med Auger-e~-kaskader og de er anvendbare som radiofarmasøytika.
NO940080A 1993-01-12 1994-01-10 Polypeptider , fremgangsmåte for deres fremstilling og farmasöytiske preparater derav NO940080L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939300510A GB9300510D0 (en) 1993-01-12 1993-01-12 Improvements in or relating to organic compounds
GB939313129A GB9313129D0 (en) 1993-06-24 1993-06-24 Improvements in or relating to organic compounds
GB939315561A GB9315561D0 (en) 1993-07-28 1993-07-28 Improvements in or relating to organic compounds

Publications (2)

Publication Number Publication Date
NO940080D0 NO940080D0 (no) 1994-01-10
NO940080L true NO940080L (no) 1994-07-13

Family

ID=27266539

Family Applications (1)

Application Number Title Priority Date Filing Date
NO940080A NO940080L (no) 1993-01-12 1994-01-10 Polypeptider , fremgangsmåte for deres fremstilling og farmasöytiske preparater derav

Country Status (11)

Country Link
EP (1) EP0607103A3 (no)
JP (1) JPH06234792A (no)
KR (1) KR940018397A (no)
CA (1) CA2113121A1 (no)
CZ (1) CZ5594A3 (no)
FI (1) FI940109L (no)
HU (1) HUT66294A (no)
IL (1) IL108308A0 (no)
NO (1) NO940080L (no)
NZ (1) NZ250653A (no)
SK (1) SK2094A3 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
US7238340B1 (en) * 1991-11-27 2007-07-03 Cis Bio International Monoamine, diamide, thiol-containing metal chelating agents
US5650134A (en) * 1993-01-12 1997-07-22 Novartis Ag (Formerly Sandoz Ltd.) Peptides
WO1996003651A1 (de) 1994-07-25 1996-02-08 Boehringer Mannheim Gmbh Metallchelat-markierte peptide
GB9417873D0 (en) 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
US5556939A (en) * 1994-10-13 1996-09-17 Merck Frosst Canada, Inc. TC or RE radionuclide labelled chelate, hexapeptide complexes useful for diagnostic or therapeutic applications
US5597894A (en) * 1995-06-05 1997-01-28 The Louisiana State University Medical Center Foundation Multi-tyrosinated somatostatin analogs
US5830431A (en) * 1995-06-07 1998-11-03 Mallinckrodt Medical, Inc. Radiolabeled peptide compositions for site-specific targeting
US5891418A (en) * 1995-06-07 1999-04-06 Rhomed Incorporated Peptide-metal ion pharmaceutical constructs and applications
US6331285B1 (en) 1996-06-05 2001-12-18 Palatin Technologies, Inc. Structurally determined cyclic metallo-constructs and applications
US6355613B1 (en) 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
ES2307325T3 (es) * 1997-11-24 2008-11-16 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Metodo para aumentar la acumulacion en tejidos de compuestos raiomarcados.
US7385025B2 (en) 2000-12-19 2008-06-10 Palatin Technologies, Inc. Metallopeptide compounds
ITMI20011708A1 (it) * 2001-08-03 2003-02-03 Bracco Imaging Spa Coniugati di peptidi, loro derivati con complessi metallici e utilizzo per i'indagine diagnostica tramite imaging per risonanza magnetica(m
GB0416062D0 (en) * 2004-07-19 2004-08-18 Amersham Plc Improved N4 chelator conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
GB9111199D0 (en) * 1991-05-23 1991-07-17 Sandoz Ltd Improvements in or relating to organic compounds

Also Published As

Publication number Publication date
AU5309394A (en) 1994-07-21
NZ250653A (en) 1995-12-21
SK2094A3 (en) 1995-01-12
FI940109L (fi) 1994-10-11
NO940080D0 (no) 1994-01-10
KR940018397A (ko) 1994-08-16
AU678778B2 (en) 1997-06-12
CA2113121A1 (en) 1994-07-13
HUT66294A (en) 1994-11-28
EP0607103A2 (en) 1994-07-20
HU9400058D0 (en) 1994-05-30
EP0607103A3 (en) 1997-07-09
JPH06234792A (ja) 1994-08-23
IL108308A0 (en) 1994-04-12
CZ5594A3 (en) 1994-07-13
FI940109A0 (fi) 1994-01-10

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