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NO930710D0 - Pro-legemidler for cck-antagonister - Google Patents

Pro-legemidler for cck-antagonister

Info

Publication number
NO930710D0
NO930710D0 NO1993930710A NO930710A NO930710D0 NO 930710 D0 NO930710 D0 NO 930710D0 NO 1993930710 A NO1993930710 A NO 1993930710A NO 930710 A NO930710 A NO 930710A NO 930710 D0 NO930710 D0 NO 930710D0
Authority
NO
Norway
Prior art keywords
pro
drugs
agents
useful
treatment
Prior art date
Application number
NO1993930710A
Other languages
English (en)
Other versions
NO300324B1 (no
NO930710L (no
Inventor
David Christopher Horwell
Martyn Clive Pritchard
Reginald Stewart Richardson
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/726,653 external-priority patent/US5340825A/en
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of NO930710D0 publication Critical patent/NO930710D0/no
Publication of NO930710L publication Critical patent/NO930710L/no
Publication of NO300324B1 publication Critical patent/NO300324B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0821Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO930710A 1990-08-31 1993-02-26 Analogifremgangsmåte til fremstilling av terapeutisk aktive forbindelser NO300324B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US57631590A 1990-08-31 1990-08-31
US07/726,653 US5340825A (en) 1990-08-31 1991-07-12 Pro drugs for CCK antagonists
PCT/US1991/006178 WO1992004038A1 (en) 1990-08-31 1991-08-29 Pro-drugs for cck antagonists

Publications (3)

Publication Number Publication Date
NO930710D0 true NO930710D0 (no) 1993-02-26
NO930710L NO930710L (no) 1993-04-21
NO300324B1 NO300324B1 (no) 1997-05-12

Family

ID=27076930

Family Applications (1)

Application Number Title Priority Date Filing Date
NO930710A NO300324B1 (no) 1990-08-31 1993-02-26 Analogifremgangsmåte til fremstilling av terapeutisk aktive forbindelser

Country Status (14)

Country Link
US (2) US5554643A (no)
EP (1) EP0546108B1 (no)
JP (1) JP3356431B2 (no)
AT (1) ATE208400T1 (no)
AU (1) AU649077B2 (no)
CA (1) CA2088980C (no)
DE (1) DE69132805T2 (no)
DK (1) DK0546108T3 (no)
ES (1) ES2167312T3 (no)
IE (1) IE913079A1 (no)
NO (1) NO300324B1 (no)
NZ (1) NZ239591A (no)
PT (1) PT98831B (no)
WO (1) WO1992004038A1 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2167312T3 (es) * 1990-08-31 2002-05-16 Warner Lambert Co Profarmacos para antagonistas de la colecistoquinina.
CZ282536B6 (cs) * 1991-07-12 1997-08-13 Warner-Lambert Company Nepřirozený dipeptoid pro výrobu léčiva pro prevenci a léčbu záchvatů panického strachu
US5217957A (en) * 1991-08-20 1993-06-08 Warner-Lambert Company Cholecystokinin antagonists useful for treating depression
US5380872A (en) * 1992-07-14 1995-01-10 Glaxo Inc. Modulators of cholecystokinin
EP1000930A3 (en) * 1992-08-13 2003-10-29 Warner-Lambert Company Tachykinin antagonists
TW281669B (no) * 1993-02-17 1996-07-21 Chugai Pharmaceutical Co Ltd
US6869957B1 (en) 1993-11-17 2005-03-22 Eli Lilly And Company Non-peptide tachykinin receptor antagonists
US6403577B1 (en) * 1993-11-17 2002-06-11 Eli Lilly And Company Hexamethyleneiminyl tachykinin receptor antagonists
US7077822B1 (en) 1994-02-09 2006-07-18 The University Of Iowa Research Foundation Stereotactic hypothalamic obesity probe
US6129685A (en) * 1994-02-09 2000-10-10 The University Of Iowa Research Foundation Stereotactic hypothalamic obesity probe
CA2152765A1 (en) 1994-06-30 1995-12-31 Jeroen Elisabeth-Joseph Knops Methods for treating a physiological disorder associated with beta amyloid peptide
US7109326B2 (en) * 1997-04-15 2006-09-19 Genentech, Inc. Halo-alkoxycarbonyl prodrugs
WO2008031221A1 (en) 2006-09-12 2008-03-20 Cephalin Pharmaceuticals Inc. Isovaline for treatment of pain
JP7509340B2 (ja) * 2016-03-14 2024-07-02 ピボット ホールディングス エルエルシー トリゴネリンベースの化合物
US20200109117A1 (en) * 2018-10-02 2020-04-09 ACCESS Association Modified Therapeutic Agent Analogs of Mefenamic Acid

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2364659A1 (fr) * 1976-09-21 1978-04-14 Commissariat Energie Atomique Medicament antagoniste de l'action de la gastrine et des polypeptides apparentes
US4757151A (en) * 1985-11-14 1988-07-12 Warner-Lambert Company 2-substituted-[2-substituted-amino]-N-arylalkyl-3-[indol-3-yl]
EP0336356A3 (en) * 1988-04-05 1991-09-25 Abbott Laboratories Derivatives of tryptophan as cck antagonists
US4997950A (en) * 1989-04-20 1991-03-05 Richard Finbar Murphy Novel C-terminal gastrin antagonists
US5278316A (en) * 1989-06-29 1994-01-11 Warner-Lambert Company N-substituted cycloalkyl and polycycloalkyl alpha-substituted Trp-Phe- and phenethylamine derivatives
NZ234264A (en) * 1989-06-29 1993-05-26 Warner Lambert Co N-substituted cycloalkyl and polycycloalkyl alpha-substituted trp-phe- and phenethylamine derivatives, and pharmaceutical compositions
ES2167312T3 (es) * 1990-08-31 2002-05-16 Warner Lambert Co Profarmacos para antagonistas de la colecistoquinina.

Also Published As

Publication number Publication date
DK0546108T3 (da) 2002-02-18
CA2088980C (en) 2002-04-16
EP0546108A4 (en) 1993-09-22
JPH06501007A (ja) 1994-01-27
NO300324B1 (no) 1997-05-12
IE913079A1 (en) 1992-03-11
JP3356431B2 (ja) 2002-12-16
EP0546108B1 (en) 2001-11-07
US5726200A (en) 1998-03-10
ES2167312T3 (es) 2002-05-16
PT98831A (pt) 1992-08-31
WO1992004038A1 (en) 1992-03-19
US5554643A (en) 1996-09-10
ATE208400T1 (de) 2001-11-15
EP0546108A1 (en) 1993-06-16
DE69132805T2 (de) 2002-10-24
NZ239591A (en) 1994-07-26
AU649077B2 (en) 1994-05-12
DE69132805D1 (de) 2001-12-13
AU8725091A (en) 1992-03-30
PT98831B (pt) 1999-02-26
CA2088980A1 (en) 1992-03-01
NO930710L (no) 1993-04-21

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