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NO900795D0 - Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkan-pyrimidinderivater. - Google Patents

Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkan-pyrimidinderivater.

Info

Publication number
NO900795D0
NO900795D0 NO900795A NO900795A NO900795D0 NO 900795 D0 NO900795 D0 NO 900795D0 NO 900795 A NO900795 A NO 900795A NO 900795 A NO900795 A NO 900795A NO 900795 D0 NO900795 D0 NO 900795D0
Authority
NO
Norway
Prior art keywords
phenylycycloalkan
piperazinyl
procedure
preparation
new
Prior art date
Application number
NO900795A
Other languages
English (en)
Other versions
NO900795L (no
Inventor
Katsuhiko Hino
Naoki Kai
Masato Sakamoto
Tatsuya Kon
Makoto Oka
Kiyoshi Furukawa
Yoshiaki Ochi
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of NO900795D0 publication Critical patent/NO900795D0/no
Publication of NO900795L publication Critical patent/NO900795L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO90900795A 1989-02-21 1990-02-20 Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkanpyrimidinderivater. NO900795L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4072989 1989-02-21

Publications (2)

Publication Number Publication Date
NO900795D0 true NO900795D0 (no) 1990-02-20
NO900795L NO900795L (no) 1990-08-22

Family

ID=12588717

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90900795A NO900795L (no) 1989-02-21 1990-02-20 Fremgangsmaate for fremstilling av nye 2-(1-piperazinyl)-4-fenylcykloalkanpyrimidinderivater.

Country Status (9)

Country Link
US (1) US5041443A (no)
EP (2) EP0484988A1 (no)
KR (1) KR910015562A (no)
AU (1) AU622976B2 (no)
CA (1) CA2010477A1 (no)
DD (1) DD297819A5 (no)
FI (1) FI900833A0 (no)
HU (1) HU204815B (no)
NO (1) NO900795L (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09502449A (ja) * 1993-09-15 1997-03-11 メルク シヤープ エンド ドーム リミテツド ドーパミン受容体サブタイプリガンドとしての縮合三環複素芳香族誘導体
ES2740424T3 (es) 2009-03-13 2020-02-05 Agios Pharmaceuticals Inc Métodos y composiciones para trastornos relacionados con la proliferación celular
SG177434A1 (en) 2009-06-29 2012-02-28 Agios Pharmaceuticals Inc Therapeutic compounds and compositions
ES2594402T3 (es) 2009-10-21 2016-12-20 Agios Pharmaceuticals, Inc. Métodos y composiciones para trastornos relacionados con la proliferación celular
CA2793836C (en) 2009-10-21 2020-03-24 Agios Pharmaceuticals, Inc. Methods and compositions for cell-proliferation-related disorders
PH12013502241A1 (en) 2011-05-03 2014-01-06 Agios Pharmaceuticals Inc Pyruvate kinase activators for use in therapy
CN102827170A (zh) * 2011-06-17 2012-12-19 安吉奥斯医药品有限公司 治疗活性组合物和它们的使用方法
CN102827073A (zh) 2011-06-17 2012-12-19 安吉奥斯医药品有限公司 治疗活性组合物和它们的使用方法
HUE038403T2 (hu) 2012-01-06 2018-10-29 Agios Pharmaceuticals Inc Terápiásan alkalmazható vegyületek és alkalmazási módszereik
US9474779B2 (en) 2012-01-19 2016-10-25 Agios Pharmaceuticals, Inc. Therapeutically active compositions and their methods of use
CA2888360A1 (en) 2012-10-15 2014-04-24 Agios Pharmaceuticals, Inc. Therapeutic compounds and compositions
US9579324B2 (en) 2013-07-11 2017-02-28 Agios Pharmaceuticals, Inc Therapeutically active compounds and their methods of use
AU2014287121B2 (en) 2013-07-11 2018-11-15 Agios Pharmaceuticals, Inc. 2,4- or 4,6-diaminopyrimidine compounds as IDH2 mutants inhibitors for the treatment of cancer
WO2015003360A2 (en) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
WO2015003355A2 (en) 2013-07-11 2015-01-15 Agios Pharmaceuticals, Inc. Therapeutically active compounds and their methods of use
US20150031627A1 (en) 2013-07-25 2015-01-29 Agios Pharmaceuticals, Inc Therapeutically active compounds and their methods of use
WO2015138839A1 (en) 2014-03-14 2015-09-17 Agios Pharmaceuticals, Inc. Pharmaceutical compositions of therapeutically active compounds
EP4344703A1 (en) 2015-06-11 2024-04-03 Agios Pharmaceuticals, Inc. Methods of using pyruvate kinase activators
MD3362065T2 (ro) 2015-10-15 2024-08-31 Servier Lab Terapie combinată care conține ivosidenib, citarabină și daunorubicina sau idarubicina pentru tratarea leucemiei acute mielogene
PT3362066T (pt) 2015-10-15 2021-11-16 Celgene Corp Terapia de combinação para tratar malignidades
US10980788B2 (en) 2018-06-08 2021-04-20 Agios Pharmaceuticals, Inc. Therapy for treating malignancies
US20230079863A1 (en) * 2021-03-29 2023-03-16 Gilead Sciences, Inc. Khk inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3305553A (en) * 1965-10-18 1967-02-21 Parke Davis & Co 2-aminoquinazoline derivatives
US3915976A (en) * 1972-09-01 1975-10-28 Sandoz Ag Substituted-4-phenyl-5h-cycloalkano(d)pyrimidines
US4133884A (en) * 1977-02-25 1979-01-09 Eli Lilly And Company Substituted pyrroloquinoxalinones and diones used in treating inflammation in warm blooded mammals
EP0022481A1 (en) * 1979-06-21 1981-01-21 Mitsubishi Yuka Pharmaceutical Co., Ltd. 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions
DE3609596A1 (de) * 1986-03-21 1987-10-01 Hoechst Ag 2-azolylmethyl-2-aryl-1,3-dioxolane und deren salze, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung
JPS6442472A (en) * 1987-08-10 1989-02-14 Kanebo Ltd Quinazoline derivative, production thereof and brain function disorder improving agent containing said derivative as active ingredient
US5021421A (en) * 1989-03-03 1991-06-04 Dainippon Pharmaceutical Co., Ltd. 2-(1-Piperazinyl)-4-phenylcycloalkanopyridine derivatives, processes for the production thereof, and pharmaceutical composition containing the same

Also Published As

Publication number Publication date
HU900861D0 (en) 1990-05-28
HUT53098A (en) 1990-09-28
AU4912290A (en) 1990-08-30
HU204815B (en) 1992-02-28
FI900833A0 (fi) 1990-02-20
EP0384228A1 (en) 1990-08-29
AU622976B2 (en) 1992-04-30
CA2010477A1 (en) 1990-08-21
DD297819A5 (de) 1992-01-23
EP0484988A1 (en) 1992-05-13
KR910015562A (ko) 1991-09-30
US5041443A (en) 1991-08-20
NO900795L (no) 1990-08-22

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