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NO893270L - PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES. - Google Patents

PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES.

Info

Publication number
NO893270L
NO893270L NO89893270A NO893270A NO893270L NO 893270 L NO893270 L NO 893270L NO 89893270 A NO89893270 A NO 89893270A NO 893270 A NO893270 A NO 893270A NO 893270 L NO893270 L NO 893270L
Authority
NO
Norway
Prior art keywords
procedure
preparation
acetic acid
acid derivatives
therapeutic active
Prior art date
Application number
NO89893270A
Other languages
Norwegian (no)
Other versions
NO893270D0 (en
Inventor
Walter Loesel
Otto Roos
Gerd Schnorrenberg
Dietrich Arndts
Georg Speck
Ilse Streller
Werner Traunecker
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of NO893270D0 publication Critical patent/NO893270D0/en
Publication of NO893270L publication Critical patent/NO893270L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO89893270A 1988-08-16 1989-08-15 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES. NO893270L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3827727A DE3827727A1 (en) 1988-08-16 1988-08-16 ANALYZED TETRAHYDROPYRIDINE IGNESE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE OF SUCH CONNECTIONS FOR CARDIRO PROTECTION

Publications (2)

Publication Number Publication Date
NO893270D0 NO893270D0 (en) 1989-08-15
NO893270L true NO893270L (en) 1990-02-19

Family

ID=6360928

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89893270A NO893270L (en) 1988-08-16 1989-08-15 PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES.

Country Status (16)

Country Link
EP (1) EP0358957A1 (en)
JP (1) JPH02160767A (en)
KR (1) KR900003129A (en)
AU (1) AU637767B2 (en)
DD (3) DD285595A5 (en)
DE (1) DE3827727A1 (en)
DK (1) DK399789A (en)
FI (1) FI893832A (en)
HU (1) HU208434B (en)
IL (1) IL91301A0 (en)
NO (1) NO893270L (en)
PH (1) PH27356A (en)
PL (1) PL161521B1 (en)
PT (1) PT91451A (en)
YU (1) YU160189A (en)
ZA (1) ZA896205B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162336A (en) * 1990-06-21 1992-11-10 Rhone-Poulenc Rorer Pharmaceuticals Inc. Tetrahydro-pyrido-indoles as cholecystokinin and gastrin antagonists
DE4041482A1 (en) * 1990-12-22 1992-06-25 Boehringer Ingelheim Kg NEW PHARMACEUTICAL USE OF CARBOCYCLIC AND HETEROCYCLICALLY ANNELATED DIHYDROPYRIDINE
DE4104257A1 (en) * 1991-02-13 1992-08-20 Boehringer Ingelheim Kg USE OF ANALYZED TETRAHYDROPYRIDINE IGNESE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL ILLNESSES
US5674878A (en) * 1992-06-22 1997-10-07 Boehringer Ingelheim Kg Anellated dihydropyridines and the use thereof for the production of pharmaceutical preparations
KR100291706B1 (en) * 1992-06-22 2001-10-24 베링거 인겔하임 카게 Closed dihydropyridine, preparation method thereof and pharmaceutical composition comprising the same
EP0620222A3 (en) * 1993-04-14 1995-04-12 Lilly Co Eli Tetrahydro-beta-carbolines.
DE4343641A1 (en) * 1993-12-21 1995-06-29 Boehringer Ingelheim Kg Anellated dihydropyridines and their use for the preparation of pharmaceutical preparations
DE4343683A1 (en) * 1993-12-21 1995-06-22 Boehringer Ingelheim Kg Anellated dihydropyridines and their use for the preparation of pharmaceutical preparations
DE59409595D1 (en) * 1993-12-21 2000-12-28 Boehringer Ingelheim Pharma FELLED DIHYDROPYRIDINE AND THEIR USE FOR THE PRODUCTION OF PHARMACEUTICAL PREPARATIONS
EP1159273A1 (en) 1999-03-02 2001-12-05 Boehringer Ingelheim Pharmaceuticals Inc. Compounds useful as reversible inhibitors of cathepsin s
US6420364B1 (en) 1999-09-13 2002-07-16 Boehringer Ingelheim Pharmaceuticals, Inc. Compound useful as reversible inhibitors of cysteine proteases
EP1458714A1 (en) * 2001-12-19 2004-09-22 H. Lundbeck A/S 3,4-dihydro-1h-isoquinoloin-2-yl-derivatives
GB2422828A (en) * 2005-02-03 2006-08-09 Hunter Fleming Ltd Tricyclic cytoprotective compounds comprising an indole residue
US8710245B2 (en) 2009-12-04 2014-04-29 Psychogenics Inc. Multicyclic compounds and methods of use thereof
CN116514761A (en) 2016-07-29 2023-08-01 赛诺维信制药公司 Compounds, compositions and uses thereof
KR20190065246A (en) 2016-07-29 2019-06-11 선오비온 파마슈티컬스 인코포레이티드 Compounds and compositions and uses thereof
IL268694B2 (en) 2017-02-16 2023-10-01 Sunovion Pharmaceuticals Inc Treatment of schizophrenia
JP7191085B2 (en) 2017-08-02 2022-12-16 サノビオン ファーマシューティカルズ インク Isochroman compounds and uses thereof
CN112135827B (en) 2018-02-16 2024-01-12 赛诺维信制药公司 Salts, crystal forms and preparation methods thereof
EP3938045A1 (en) 2019-03-14 2022-01-19 Sunovion Pharmaceuticals Inc. Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof
MX2022012833A (en) 2020-04-14 2022-11-07 Sunovion Pharmaceuticals Inc (s)-(4,5-dihydro-7h-thieno[2,3-c]pyran-7-yl)-n-methylmethanamine for treating neurological and psychiatric disorders.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3021331A (en) * 1959-07-20 1962-02-13 Pfizer & Co C Azabenzopyridocolines
DE2361390A1 (en) * 1973-12-10 1975-06-19 Merck Patent Gmbh ISOCHINOLINE DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION
HU174697B (en) * 1976-12-30 1980-03-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new 6,7-dimethoxy-1,2,3,4-tetrahydro-1-isoquinolin-acetamide derivatives
FR2447921A1 (en) * 1979-02-05 1980-08-29 Synthelabo IMIDAZO AND PYRIMIDO-PYRIDO-INDOLES AND THEIR APPLICATION IN THERAPEUTICS
FR2455044A1 (en) * 1979-04-26 1980-11-21 Synthelabo PYRIDO-INDOLES AND THEIR APPLICATION IN THERAPEUTICS
DE3013906A1 (en) * 1980-04-11 1981-10-15 C.H. Boehringer Sohn, 6507 Ingelheim SUBSTITUTED (ALPHA) -AMINOCARBONYL-L-BENZYL-3,4-DIHYDRO-ISOCHINOLINE, METHOD FOR THE PRODUCTION AND USE THEREOF
DE3229215A1 (en) * 1982-08-05 1984-02-09 Basf Ag, 6700 Ludwigshafen 1- (HALOGENALKYL) -1,2,3,4-TETRAHYDRO-SS-CARBOLINE, THEIR PRODUCTION AND USE
DE3309596A1 (en) * 1982-08-05 1984-04-05 Basf Ag, 6700 Ludwigshafen 2-SUBSTITUTED 1- (3'-AMINOALKYL) -1,2,3,4-TETRAHYDRO-SS-CARBOLINE, THEIR PRODUCTION AND USE AS MEDICINAL PRODUCT
DE3621413A1 (en) * 1986-06-26 1988-01-07 Boehringer Ingelheim Kg USE OF CARBOCYCLIC AND HETEROCYCLICALLY FURNISHED DIHYDROPYRIDINE AS A CARDIOPROTECTIVE AGENT AND NEW HETEROCYCLIC AND CARBOCYCLICALLY FURNISHED DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND ITS ADDITIONAL PRODUCTS
IL86131A0 (en) * 1987-04-24 1988-11-15 Boehringer Ingelheim Kg Benzo-and thieno-3,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DD295379A5 (en) 1991-10-31
DE3827727A1 (en) 1990-02-22
AU637767B2 (en) 1993-06-10
AU3992589A (en) 1990-02-22
DD285595A5 (en) 1990-12-19
DK399789D0 (en) 1989-08-15
DD297640A5 (en) 1992-01-16
HU208434B (en) 1993-10-28
ZA896205B (en) 1991-04-24
NO893270D0 (en) 1989-08-15
DK399789A (en) 1990-02-17
YU160189A (en) 1992-09-07
IL91301A0 (en) 1990-03-19
HUT51277A (en) 1990-04-28
PH27356A (en) 1993-06-22
KR900003129A (en) 1990-03-23
PT91451A (en) 1990-03-08
PL161521B1 (en) 1993-07-30
FI893832A0 (en) 1989-08-15
FI893832A (en) 1990-02-17
JPH02160767A (en) 1990-06-20
EP0358957A1 (en) 1990-03-21

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