NO882004L - Syntese av dpdp-(mono)eddiksyre analog. - Google Patents

Syntese av dpdp-(mono)eddiksyre analog.

Info

Publication number: NO882004L
Authority: NO; Norway
Prior art keywords: dpdp; mono; synthesis; acetic acid; acid analog
Prior art date: 1987-05-08

Application number

NO88882004A

Other languages

English (en)

Other versions

NO882004D0 (no

NO177462C (no

NO177462B (no

Inventor

Scott M Rocklage

Steven C Quay

Original Assignee

Salutar Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-05-08

Filing date

1988-05-06

Publication date

1988-11-09

1988-05-06 Application filed by Salutar Inc filed Critical Salutar Inc

1988-05-06 Publication of NO882004D0 publication Critical patent/NO882004D0/no

1988-11-09 Publication of NO882004L publication Critical patent/NO882004L/no

1995-06-12 Publication of NO177462B publication Critical patent/NO177462B/no

1995-09-20 Publication of NO177462C publication Critical patent/NO177462C/no

Links

SQKUFYLUXROIFM-UHFFFAOYSA-N 2-[2-[carboxymethyl-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methyl]amino]ethyl-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methyl]amino]acetic acid Chemical compound CC1=NC=C(COP(O)(O)=O)C(CN(CCN(CC(O)=O)CC=2C(=C(C)N=CC=2COP(O)(O)=O)O)CC(O)=O)=C1O SQKUFYLUXROIFM-UHFFFAOYSA-N 0.000 title 1
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical class CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 title 1
230000015572 biosynthetic process Effects 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Physics & Mathematics (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Radiology & Medical Imaging (AREA)
Animal Behavior & Ethology (AREA)
Biochemistry (AREA)
Epidemiology (AREA)
Condensed Matter Physics & Semiconductors (AREA)
High Energy & Nuclear Physics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Signal Processing (AREA)
Engineering & Computer Science (AREA)
General Physics & Mathematics (AREA)
Molecular Biology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Magnetic Resonance Imaging Apparatus (AREA)
Measuring And Recording Apparatus For Diagnosis (AREA)
Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

NO882004A 1987-05-08 1988-05-06 Metallionchelat av en chelatdannende forbindelse samt magnetisk resonansavbildende kontrastmedium NO177462C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/047,614 US4933456A (en)	1987-05-08	1987-05-08	Dipyridoxyl phosphate NMRI contrast agents

Publications (4)

Publication Number	Publication Date
NO882004D0 NO882004D0 (no)	1988-05-06
NO882004L true NO882004L (no)	1988-11-09
NO177462B NO177462B (no)	1995-06-12
NO177462C NO177462C (no)	1995-09-20

Family

ID=21949962

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO882004A NO177462C (no)	1987-05-08	1988-05-06	Metallionchelat av en chelatdannende forbindelse samt magnetisk resonansavbildende kontrastmedium
NO1998004C NO1998004I1 (no)	1987-05-08	1998-01-19	Mangafodipir

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO1998004C NO1998004I1 (no)	1987-05-08	1998-01-19	Mangafodipir

Country Status (20)

Country	Link
US (1)	US4933456A (no)
EP (1)	EP0290047B1 (no)
JP (1)	JP2512524B2 (no)
AR (1)	AR246956A1 (no)
AT (1)	ATE118010T1 (no)
AU (1)	AU613363B2 (no)
BR (1)	BR1100623A (no)
CA (1)	CA1322003C (no)
DE (2)	DE3852906T2 (no)
DK (1)	DK173849B1 (no)
ES (1)	ES2066768T3 (no)
FI (1)	FI88164C (no)
GR (1)	GR3015884T3 (no)
HK (1)	HK55195A (no)
IE (1)	IE66368B1 (no)
IL (1)	IL86298A (no)
NL (1)	NL970040I2 (no)
NO (2)	NO177462C (no)
NZ (1)	NZ224537A (no)
SG (1)	SG30569G (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5422096A (en) *	1985-05-08	1995-06-06	The General Hospital Corporation	Hydroxy-aryl metal chelates for diagnostic NMR imaging
US5250285A (en) *	1985-05-08	1993-10-05	The General Hospital Corporation	Hydroxy-aryl metal chelates for diagnostic NMR imaging
US4994259A (en) *	1987-05-08	1991-02-19	Salutar, Inc.	Improvement in the method of NMR imaging employing a manganese II chelates of N,N'-bis[pyridoxal-alkylene (or cycloalkylene) (or arylene)]-N,N'-diacetic acid derivatives
US4827426A (en) *	1987-05-18	1989-05-02	The Coca-Cola Company	Data acquisition and processing system for post-mix beverage dispensers
US5087440A (en) *	1989-07-31	1992-02-11	Salutar, Inc.	Heterocyclic derivatives of DTPA used for magnetic resonance imaging
AU7346091A (en) *	1990-03-02	1991-09-18	Byk Gulden Lomberg Chemische Fabrik Gmbh	Preparations for mr diagnosis
JPH06500090A (ja) *	1990-08-15	1994-01-06	ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング	錯塩の新規使用
DE4026103A1 (de) *	1990-08-17	1992-02-20	Byk Gulden Lomberg Chem Fab	Neue verwendung von komplexsalzen
EP0494616A1 (de) *	1991-01-07	1992-07-15	Byk Gulden Lomberg Chemische Fabrik Gmbh	Kontrastmittel für die MR-Diagnostik
DE4107570A1 (de) *	1991-03-07	1992-11-19	Diagnostikforschung Inst	Chelate, deren metallkomplexe sowie ihre verwendung in diagnostik und therapie
WO1992021017A1 (en) *	1991-05-23	1992-11-26	Unger Evan C	Liposoluble compounds for magnetic resonance imaging
US5385719A (en) *	1991-09-24	1995-01-31	Unger; Evan C.	Copolymers and their use as contrast agents in magnetic resonance imaging and in other applications
US5582814A (en) *	1994-04-15	1996-12-10	Metasyn, Inc.	1-(p-n-butylbenzyl) DTPA for magnetic resonance imaging
CA2190727C (en) *	1994-05-19	2006-07-18	Sudhakar Kasina	Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
TW319763B (no)	1995-02-01	1997-11-11	Epix Medical Inc
SG81898A1 (en) *	1995-08-11	2001-07-24	Sumitomo Chemical Co	Olefin polymerization catalyst component, olefin polymerization catalyst and process for producing olefin polymer
US6005083A (en) *	1997-03-28	1999-12-21	Neorx Corporation	Bridged aromatic substituted amine ligands with donor atoms
AU8227398A (en) *	1997-07-01	1999-01-25	Nycomed Imaging As	Method
JP2001527072A (ja) *	1997-12-23	2001-12-25	ニユコメド・イメージング・アクシエセルカペト	一酸化窒素を放出するキレート化剤およびその治療上の使用
FR2867473B1 (fr)	2004-03-12	2006-06-23	Guerbet Sa	Compose de porphyrines et utilisation a haut champ en irm
WO2013102806A1 (en) *	2012-01-05	2013-07-11	Pledpharma Ab	Calmangafodipir, a new chemical entity, and other mixed metal complexes, methods of preparation, compositions, and methods of treatment

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3632637A (en) *	1968-02-13	1972-01-04	Arthur E Martell	Hydroxyaryl-containing aminocarboxylic chelating agents
AU485693B2 (en) *	1973-08-24	1976-02-05	The Council Ofthe Institute Of Medical And Veterinary Science, Andthe Universityof Adelaide Gariti Cancer Foundation	New radiopharmaceuticals for cholescintigraphy
JPS5569517A (en) *	1978-11-20	1980-05-26	Nippon Mejifuijitsukusu Kk	Labelling preparation for labelling of erythrocytes with radio-active technetium
JPS5791927A (en) *	1980-11-27	1982-06-08	Nippon Mejifuijitsukusu Kk	Technetium-99m labelled diagnosticum
US4647447A (en) *	1981-07-24	1987-03-03	Schering Aktiengesellschaft	Diagnostic media
JPS5896031A (ja) *	1981-12-03	1983-06-07	Nippon Mejifuijitsukusu Kk	放射性診断剤およびその製造用組成物
US4637929A (en) *	1985-01-04	1987-01-20	Salutar, Inc.	Ferrioxamine-paramagnetic contrast agents for MR imaging, composition, apparatus and use
US4935518A (en)	1987-05-08	1990-06-19	Salutar, Inc.	Manganese(II), chelate contrast agents derived from N,N'-bis-(pyridoxal ethylene diamine-N,N')-diacetic acid and derivatives thereof
US4842845A (en) *	1987-05-08	1989-06-27	Salutar, Inc.	Radioactive metal chelates for dipyridoxyl phosphate

1986
- 1986-05-04 AR AR86310757A patent/AR246956A1/es active
1987
- 1987-05-08 US US07/047,614 patent/US4933456A/en not_active Expired - Lifetime
1988
- 1988-04-28 CA CA000565428A patent/CA1322003C/en not_active Expired - Lifetime
- 1988-05-06 NO NO882004A patent/NO177462C/no not_active IP Right Cessation
- 1988-05-06 DK DK198802516A patent/DK173849B1/da not_active IP Right Cessation
- 1988-05-06 FI FI882125A patent/FI88164C/fi not_active IP Right Cessation
- 1988-05-06 AU AU15680/88A patent/AU613363B2/en not_active Expired
- 1988-05-06 NZ NZ224537A patent/NZ224537A/en unknown
- 1988-05-06 EP EP88107346A patent/EP0290047B1/en not_active Expired - Lifetime
- 1988-05-06 SG SG1995904462A patent/SG30569G/en unknown
- 1988-05-06 DE DE3852906T patent/DE3852906T2/de not_active Expired - Lifetime
- 1988-05-06 ES ES88107346T patent/ES2066768T3/es not_active Expired - Lifetime
- 1988-05-06 IL IL86298A patent/IL86298A/xx not_active IP Right Cessation
- 1988-05-06 IE IE136688A patent/IE66368B1/en not_active IP Right Cessation
- 1988-05-06 AT AT88107346T patent/ATE118010T1/de active
- 1988-05-06 DE DE1997175088 patent/DE19775088I2/de active Active
- 1988-05-07 JP JP63109931A patent/JP2512524B2/ja not_active Expired - Lifetime
1995
- 1995-04-11 HK HK55195A patent/HK55195A/xx not_active IP Right Cessation
- 1995-04-19 GR GR950401021T patent/GR3015884T3/el unknown
1997
- 1997-05-13 BR BR1100623-4A patent/BR1100623A/pt active IP Right Grant
- 1997-11-14 NL NL970040C patent/NL970040I2/nl unknown
1998
- 1998-01-19 NO NO1998004C patent/NO1998004I1/no unknown

Also Published As

Publication number	Publication date
DK251688D0 (da)	1988-05-06
JP2512524B2 (ja)	1996-07-03
EP0290047B1 (en)	1995-02-01
NZ224537A (en)	1991-06-25
IE66368B1 (en)	1995-12-27
EP0290047A3 (en)	1990-04-25
JPS63280087A (ja)	1988-11-17
ATE118010T1 (de)	1995-02-15
BR1100623A (pt)	1999-12-07
GR3015884T3 (en)	1995-07-31
CA1322003C (en)	1993-09-07
DE3852906T2 (de)	1995-06-22
AU1568088A (en)	1988-11-10
FI882125A0 (fi)	1988-05-06
FI88164B (fi)	1992-12-31
ES2066768T3 (es)	1995-03-16
FI882125A (fi)	1988-11-09
NO882004D0 (no)	1988-05-06
HK55195A (en)	1995-04-21
NO1998004I1 (no)	1998-01-19
NL970040I1 (nl)	1998-02-02
AR246956A1 (es)	1994-10-31
AU613363B2 (en)	1991-08-01
DK251688A (da)	1988-11-09
DE19775088I2 (de)	2001-05-23
DE3852906D1 (de)	1995-03-16
DK173849B1 (da)	2001-12-27
NO177462C (no)	1995-09-20
FI88164C (fi)	1993-04-13
IL86298A (en)	1992-11-15
SG30569G (en)	1995-09-18
IL86298A0 (en)	1988-11-15
EP0290047A2 (en)	1988-11-09
IE881366L (en)	1988-11-08
NO177462B (no)	1995-06-12
US4933456A (en)	1990-06-12
NL970040I2 (nl)	1998-06-02

Publication	Publication Date	Title
NO882004L (no)	1988-11-09	Syntese av dpdp-(mono)eddiksyre analog.
NO874251D0 (no)	1987-10-12	Kryssbundete estere av hyalusronsyre.
NO872716D0 (no)	1987-06-29	Fremgangsmaate for fremstilling av estere av alginsyre.
NO862734L (no)	1987-01-09	Fremgangsmaate for fremstilling av hyaluronsyreestere.
NO173498C (no)	1993-12-22	Analogifremgangsmaate for fremstilling av substituerte 9-amino-tetrahydroakridiner
NO862408D0 (no)	1986-06-17	Fremgangsmaate for fremstilling av thiazolidin-4(s)-karboksylsyrederivater.
NO885601D0 (no)	1988-12-16	Eventuelt kvataererte fettsyreestre av oxalkylerte alkyl-alkylendiaminer.
NO842526L (no)	1984-12-27	Fremgangsmaate for fremstilling av salpetersyreestere
PT87153A (pt)	1988-05-01	Process for the preparation of acid ribofuranuronic derivatives
NO884153D0 (no)	1988-09-19	Fremgangsmaate for fremstilling av fenoksyftalsyreanhydrider.
PT88545A (pt)	1988-10-01	Process for the manufacture of benzimidazoline-2-oxo-1-carboxylic acid derivative compounds
NO822127L (no)	1983-01-18	Fremgangsmaate for fremstilling av estere av 3-metylflavon-8-karboksylsyre.
JPS6438082A (en)	1989-02-08	Manufacture of ascorbic acid derivative
NO893326D0 (no)	1989-08-18	Fremgangsmaate for noeytralisering av svovelsyre inneholdende sinkioner.
JPS6470459A (en)	1989-03-15	Manufacture of 2-arylthiobenzoic acid
FI945353A0 (fi)	1994-11-14	Entsymaattinen menetelmä (S)-6-metoksyyli-alfa-metyyli-2-naftaleenietikkahapon valmistamiseksi
JPS6431755A (en)	1989-02-02	Manufacture of aminoaryl-sulfonic acid
JPS6422864A (en)	1989-01-25	Manufacture of piperidinylcyclopentylheptenoic acid derivative
DE3888505D1 (de)	1994-04-21	Herstellung von Zimtsäureestern.
JPS6445355A (en)	1989-02-17	Manufacture of alkanedisulfonic acid
NO172743C (no)	1993-09-01	Fremgangsmaate for fremstilling av kinolincarboxylsyrederivater
GB8717997D0 (en)	1987-09-03	Derivatives of benzoyloxyacetic acid
NO874724D0 (no)	1987-11-12	Fremgangsmaate for fremstilling av hydrerte 1-fenoksy-alkylpyridin-3-karboksylsyreforbindelser.
IE871497L (en)	1987-12-06	Derivatives of 4-phenyl-4-oxo-2-butenoic acid.
NO874747D0 (no)	1987-11-13	Fremgangsmaate til fremstilling av hydratiserte 1-benzooksacykloalkylpyridinkarboksylsyreforbindelser.

Legal Events

Date	Code	Title	Description
2008-06-23	MK1K	Patent expired
2012-06-11	MK1K	Patent expired