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NO824252L - N-hydroxyethylerte 2,4,6-trijodisofthalsyre-bis-trihydroxybutylamider, fremstilling av disse og roentgenkontrastmidler inneholdende disse - Google Patents

N-hydroxyethylerte 2,4,6-trijodisofthalsyre-bis-trihydroxybutylamider, fremstilling av disse og roentgenkontrastmidler inneholdende disse

Info

Publication number
NO824252L
NO824252L NO824252A NO824252A NO824252L NO 824252 L NO824252 L NO 824252L NO 824252 A NO824252 A NO 824252A NO 824252 A NO824252 A NO 824252A NO 824252 L NO824252 L NO 824252L
Authority
NO
Norway
Prior art keywords
triododisophthalic
trihydroxybutylamides
roentgencontracting
hydroxyethyltered
bis
Prior art date
Application number
NO824252A
Other languages
English (en)
Inventor
Heinrich Pfeiffer
Wolfgang Muetzel
Ulrich Speck
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO824252L publication Critical patent/NO824252L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/20—Free hydroxyl or mercaptan
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO824252A 1981-12-18 1982-12-17 N-hydroxyethylerte 2,4,6-trijodisofthalsyre-bis-trihydroxybutylamider, fremstilling av disse og roentgenkontrastmidler inneholdende disse NO824252L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813150916 DE3150916A1 (de) 1981-12-18 1981-12-18 N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel"

Publications (1)

Publication Number Publication Date
NO824252L true NO824252L (no) 1983-06-20

Family

ID=6149449

Family Applications (1)

Application Number Title Priority Date Filing Date
NO824252A NO824252L (no) 1981-12-18 1982-12-17 N-hydroxyethylerte 2,4,6-trijodisofthalsyre-bis-trihydroxybutylamider, fremstilling av disse og roentgenkontrastmidler inneholdende disse

Country Status (10)

Country Link
US (1) US4547357A (no)
EP (1) EP0082803A1 (no)
JP (1) JPS58110551A (no)
AU (1) AU9165482A (no)
CA (1) CA1189533A (no)
DE (1) DE3150916A1 (no)
DK (1) DK544682A (no)
ES (1) ES8308535A1 (no)
GR (1) GR78422B (no)
NO (1) NO824252L (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204086A (en) * 1982-10-01 1993-04-20 Nycomed Imaging As X-ray contrast agent
US4584401A (en) * 1983-10-20 1986-04-22 Biophysica Foundation Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media
US4954348A (en) * 1985-08-09 1990-09-04 Cook Imaging Corporation Non-ionic polyol contrast media from ionic contrast media
JPH0813794B2 (ja) * 1985-08-09 1996-02-14 クツク イマジング，インコ−ポレイテイド イオン性コントラスト媒体からの非イオン性ポリオ−ルコントラスト媒体
US5035877A (en) * 1985-08-09 1991-07-30 Cook Imaging Corporation Non-ionic contrast media from ionic contrast media
JPH0420687Y2 (no) * 1986-10-21 1992-05-12
ATE79368T1 (de) * 1987-05-22 1992-08-15 Bracco Spa Herstellung von 5-acylamino-2,4,6-trijodo- oder tribromo-benzoesaeure-derivate.
IL94718A (en) * 1989-07-05 1994-10-21 Schering Ag Non-ionic carboxamide contrast agent and method of preparation
US5698739A (en) * 1989-07-05 1997-12-16 Schering Aktiengesellschaft Carboxamide non-ionic contrast media
IL96324A (en) * 1989-11-29 1995-01-24 Squibb & Sons Inc History of 5-amino-2,4,6-triadiodo-1,3-benzenecarboxylic acid, processes for their preparation, and methods used as contrast agents
US5614638A (en) * 1989-11-29 1997-03-25 Bracco International B.V. Nonionic radiographic contrast agents
DE4009119A1 (de) * 1990-03-19 1991-09-26 Schering Ag 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
DE4109169A1 (de) * 1991-03-20 1992-09-24 Koehler Chemie Dr Franz Wasserloesliche nicht ionische roentgenkontrastmittel sowie mittel und verfahren zu ihrer herstellung
US5318770A (en) * 1991-10-25 1994-06-07 Mallinckrodt Medical, Inc. Trifluoromethyl analogs of X-ray contrast media for magnetic resonance imaging
FR2687669B1 (fr) * 1992-02-24 1997-12-19 Guerbet Sa Composes utilisables dans des produits de contraste pour la radiographie.
US5278311A (en) * 1992-06-05 1994-01-11 E. R. Squibb & Sons, Inc. Nonionic radiographic contrast agents
IT1256162B (it) * 1992-10-27 1995-11-29 Zambon Spa Processo per la preparazione di un intermedio della sintesi organica
IL110391A (en) * 1993-07-30 1998-12-06 Zambon Spa Process for the formation of infamidol
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
NZ751256A (en) 2016-09-27 2020-05-29 Bayer Pharma AG Method for producing the crystalline form of modification a of calcobutrol
CN110023279B (zh) * 2016-12-05 2022-03-11 伯拉考成像股份公司 放射照相剂中间体的机械化学合成

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4021481A (en) * 1969-06-27 1977-05-03 Nyegaard & Co. A/S Amido derivatives of 2,4,6-triiodobenzoic acids containing at least one N-hydroxyalkyl and at least two hydroxyl groups
SE392100B (sv) * 1969-06-27 1977-03-14 Nyegaard & Co As Trijodbensoylaminer till anvendning sasom rontgenkontrastmedel eller for separation av biologiska material
GB1495679A (en) * 1974-06-17 1977-12-21 Mallinckrodt Inc Substituted isophthalamic acids
CH608189A5 (no) * 1974-12-13 1978-12-29 Savac Ag
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
IT1193761B (it) * 1978-07-04 1988-08-24 Nyegaard & Co As Procedimento per preparare una soluzione sterile stabile di un agente di cotrasto per raggi x
DE2909439A1 (de) * 1979-03-08 1980-09-18 Schering Ag Neue nichtionische roentgenkontrastmittel
IT1193211B (it) * 1979-08-09 1988-06-15 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
US4341756A (en) * 1980-01-31 1982-07-27 The Regents Of The University Of California Novel amino-dioxepane intermediates for the synthesis of new non-ionic contrast media
US4396598A (en) * 1982-01-11 1983-08-02 Mallinckrodt, Inc. Triiodoisophthalamide X-ray contrast agent

Also Published As

Publication number Publication date
AU9165482A (en) 1983-06-23
DE3150916A1 (de) 1983-06-30
EP0082803A1 (de) 1983-06-29
ES518180A0 (es) 1983-10-01
JPH039900B2 (no) 1991-02-12
CA1189533A (en) 1985-06-25
DE3150916C2 (no) 1990-11-22
JPS58110551A (ja) 1983-07-01
GR78422B (no) 1984-09-27
DK544682A (da) 1983-06-19
US4547357A (en) 1985-10-15
ES8308535A1 (es) 1983-10-01

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