NO790903L - Fremgangsmaate ved fremstilling av ornithin og argininsalter av forgrenede ketosyrer - Google Patents

Fremgangsmaate ved fremstilling av ornithin og argininsalter av forgrenede ketosyrer

Info

Publication number: NO790903L
Authority: NO; Norway
Prior art keywords: ornithin; arginin; salts; procedure; preparation
Prior art date: 1978-03-17

Application number

NO790903A

Other languages

English (en)

Other versions

NO151119B (no

NO151119C (no

Inventor

Mackenzie Walser

Original Assignee

Univ Johns Hopkins

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-03-17

Filing date

1979-03-16

Publication date

1979-09-18

1979-03-16 Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins

1979-09-18 Publication of NO790903L publication Critical patent/NO790903L/no

1984-11-05 Publication of NO151119B publication Critical patent/NO151119B/no

1985-02-13 Publication of NO151119C publication Critical patent/NO151119C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Gastroenterology & Hepatology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO790903A 1978-03-17 1979-03-16 Analogifremgangsmaate ved fremstilling av terapeutisk aktive ornithin og argininsalter av forgrenede ketosyrer NO151119C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US05/887,570 US4228099A (en)	1978-03-17	1978-03-17	Ornithine and arginine salts of branched chain keto acids and uses in treatment of hepatic and renal disorders

Publications (3)

Publication Number	Publication Date
NO790903L true NO790903L (no)	1979-09-18
NO151119B NO151119B (no)	1984-11-05
NO151119C NO151119C (no)	1985-02-13

Family

ID=25391422

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO790903A NO151119C (no)	1978-03-17	1979-03-16	Analogifremgangsmaate ved fremstilling av terapeutisk aktive ornithin og argininsalter av forgrenede ketosyrer

Country Status (17)

Country	Link
US (1)	US4228099A (no)
JP (1)	JPS5838421B2 (no)
AU (1)	AU517505B2 (no)
BE (1)	BE874900A (no)
CA (1)	CA1115729A (no)
DE (1)	DE2910221A1 (no)
DK (1)	DK153542C (no)
ES (1)	ES478710A1 (no)
FI (1)	FI72118C (no)
FR (1)	FR2419723A1 (no)
GB (1)	GB2017094B (no)
IE (1)	IE48336B1 (no)
IT (1)	IT1202904B (no)
LU (1)	LU81057A1 (no)
NL (1)	NL7902136A (no)
NO (1)	NO151119C (no)
SE (1)	SE446724B (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4296127A (en) *	1979-04-18	1981-10-20	The Johns Hopkins University	Mixed salts of essential or semi-essential amino acids and nitrogen-free analogs thereof
DE3438455A1 (de) *	1984-10-19	1986-06-26	Institut Dr. Ziegler, Bettingen	L-lysin- und l-histidinpyruvat
US4677121A (en) *	1985-01-22	1987-06-30	The Johns Hopkins University	Method of inhibiting muscle protein degradation
US4752619A (en) *	1985-12-23	1988-06-21	The Johns Hopkins University	Nutritional supplement for treatment of uremia
US4871552A (en) *	1986-09-25	1989-10-03	W. R. Grace & Co.-Conn.	Hydantoins as animal food supplements
US4744990A (en) *	1986-09-25	1988-05-17	W. R. Grace & Co.	Hydantoins as animal food supplements
US5639731A (en) *	1987-05-22	1997-06-17	Pripps Bryggerier Ab	Amino acids for the preparation of a beverage
FR2615734B1 (fr) *	1987-05-27	1989-12-01	Synthelabo	Compositions pharmaceutiques contenant un melange de sels de cetoacides et d'amino-acides utiles pour le traitement de l'uremie
FR2618331B1 (fr) *	1987-07-23	1991-10-04	Synthelabo	Compositions pharmaceutiques utiles pour le traitement de l'uremie
AT393079B (de) *	1989-03-06	1991-08-12	Lubec Gert	Pharmazeutische verwendung von agmatin
AT393080B (de) *	1988-11-25	1991-08-12	Lubec Gert	Pharmazeutische verwendung von arginin (salzen)
SE462463B (sv) *	1988-12-02	1990-07-02	Decken Alexandra V D	Livs- och fodermedel innehaallande ketosyror
JP2522034B2 (ja) *	1988-12-27	1996-08-07	味の素株式会社	α−ケト酸・アミノ酸塩化合物及びその製造方法
US5210098A (en) *	1990-09-21	1993-05-11	Regents Of The University Of Minnesota	Use of pyruvate to treat acute renal failure
US5234696A (en) *	1991-12-27	1993-08-10	Abbott Laboratories	Method of producing tablets, tablets produced thereby, and method of treatment using same
MX9602035A (es)	1994-10-07	1997-06-28	Firmenich & Cie	Composiciones y metodo para proporcionar sabor.
US5591736A (en) *	1995-07-03	1997-01-07	The Johns Hopkins University	Method of retarding the progression of chronic renal failure
JP2004527529A (ja) *	2001-04-04	2004-09-09	クリティカルセラピューティックスインコーポレイテッド	急性腎不全を予防するための方法
US7772280B2 (en) *	2004-11-15	2010-08-10	Kyowa Hakko Bio Co., Ltd.	Crystals of L-ornithine and process for producing the same
MX2007006171A (es) *	2004-11-26	2007-10-08	Ucl Business Plc	Composiciones que comprenden ornitina y acetato.
GB0426141D0 (en) *	2004-11-26	2004-12-29	Ucl Biomedica Plc	Treatment
KR101844605B1 (ko)	2009-04-03	2018-04-02	오세라 테라퓨틱스, 아이엔씨.	Ｌ-오르니틴 페닐 아세테이트, 및 이의 제조방법
ES2728948T3 (es)	2009-06-08	2019-10-29	Ucl Business Plc	Tratamiento de la inflamación cerebral usando Fenilacetato de L-Ornitina
US8946473B2 (en)	2010-10-06	2015-02-03	Ocera Therapeutics, Inc.	Methods of making L-ornithine phenyl acetate
JP6797117B2 (ja)	2014-11-24	2020-12-09	ユーシーエルビジネスリミテッド	アンモニア降下療法を用いた肝星細胞活性化関連疾患の処置
US10835506B2 (en)	2015-08-18	2020-11-17	Ocera Therapeutics, Inc.	Treatment and prevention of muscle loss using L-ornithine in combination with at least one of phenylacetate and phenylbutyrate
CN106674057A (zh) *	2015-11-09	2017-05-17	江西乐维生物药业有限公司	L-精氨酸a-酮基异己酸盐的制备方法
US11219611B2 (en)	2015-11-13	2022-01-11	Ocera Therapeutics, Inc.	Formulations of L-ornithine phenylacetate
WO2017090007A1 (en) *	2015-11-29	2017-06-01	Rao M Surya	Compositions and methods for the treatment of urea cycle disorders and hepatic diseases
US11066352B2 (en)	2017-05-11	2021-07-20	Ocera Therapeutics, Inc.	Processes of making L-ornithine phenylacetate
US12109254B2 (en)	2017-11-29	2024-10-08	Edgar Hull	Vitamins and alpha keto acid compositions for use in a treatment program for chronic kidney disease patients
WO2019108809A2 (en)	2017-11-29	2019-06-06	Hull Edgar L Jr	Alpha keto acid compositions for treating hypo-albuminemia
US11484579B2 (en)	2017-11-29	2022-11-01	Edgar L Hull	Vitamins and alpha keto acid compositions for use in a treatment program for chronic kidney disease patients

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA814483A (en) *		1969-06-03	Abe Kyuji	L-ornithine-l-aspartate
GB1034358A (en)	1963-05-01	1966-06-29	Chugai Pharmaceutical Co Ltd	Body-protein-biosynthesis promoting composition
FR1432756A (fr)	1965-02-11	1966-03-25	D Opochimiotherapie Lab	Pyruvates d'amino-acides et leur procédé de préparation
US3441650A (en) *	1965-07-23	1969-04-29	Lab Jacques Logeais Sa	Therapy of ammonical intoxications by di-l-ornithine alpha-ketoglutarate
DE2335215B2 (de) *	1972-07-13	1979-04-05	The Johns Hopkins University, Baltimore, Md. (V.St.A.)	Verwendung einer Mischung bei der Bekämpfung von zur Urämie führenden Nierenerkrankungen
US4100293A (en) *	1974-04-15	1978-07-11	The Johns Hopkins University	Treatment of hepatic disorders with therapeutic compositions comprising keto analogs of essential amino acids
US3950529A (en) *	1975-02-03	1976-04-13	Massachusetts General Hospital	Amino acid formulations for patients with liver disease and method of using same

1978
- 1978-03-17 US US05/887,570 patent/US4228099A/en not_active Expired - Lifetime
1979
- 1979-03-14 FR FR7906533A patent/FR2419723A1/fr active Granted
- 1979-03-15 DE DE19792910221 patent/DE2910221A1/de active Granted
- 1979-03-15 AU AU45154/79A patent/AU517505B2/en not_active Expired
- 1979-03-16 NO NO790903A patent/NO151119C/no unknown
- 1979-03-16 ES ES478710A patent/ES478710A1/es not_active Expired
- 1979-03-16 DK DK110879A patent/DK153542C/da not_active IP Right Cessation
- 1979-03-16 IT IT21071/79A patent/IT1202904B/it active
- 1979-03-16 GB GB7909350A patent/GB2017094B/en not_active Expired
- 1979-03-16 LU LU81057A patent/LU81057A1/xx unknown
- 1979-03-16 FI FI790901A patent/FI72118C/fi not_active IP Right Cessation
- 1979-03-16 CA CA323,574A patent/CA1115729A/en not_active Expired
- 1979-03-16 BE BE0/194065A patent/BE874900A/xx not_active IP Right Cessation
- 1979-03-16 JP JP54030069A patent/JPS5838421B2/ja not_active Expired
- 1979-03-16 SE SE7902401A patent/SE446724B/sv not_active IP Right Cessation
- 1979-03-19 NL NL7902136A patent/NL7902136A/xx not_active Application Discontinuation
- 1979-08-08 IE IE993/79A patent/IE48336B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
IT1202904B (it)	1989-02-15
FI72118C (fi)	1987-04-13
IE790993L (en)	1979-09-17
DK153542C (da)	1988-12-05
AU517505B2 (en)	1981-08-06
AU4515479A (en)	1979-09-20
SE446724B (sv)	1986-10-06
FR2419723B1 (no)	1982-10-29
NL7902136A (nl)	1979-09-19
FI790901A (fi)	1979-09-18
US4228099A (en)	1980-10-14
JPS54163518A (en)	1979-12-26
FR2419723A1 (fr)	1979-10-12
SE7902401L (sv)	1979-10-16
FI72118B (fi)	1986-12-31
CA1115729A (en)	1982-01-05
JPS5838421B2 (ja)	1983-08-23
NO151119B (no)	1984-11-05
DE2910221A1 (de)	1979-09-20
NO151119C (no)	1985-02-13
DK153542B (da)	1988-07-25
LU81057A1 (fr)	1979-09-07
GB2017094B (en)	1982-07-07
DE2910221C2 (no)	1988-04-28
IE48336B1 (en)	1984-12-12
BE874900A (fr)	1979-07-16
GB2017094A (en)	1979-10-03
ES478710A1 (es)	1980-01-16
IT7921071A0 (it)	1979-03-16
DK110879A (da)	1979-09-18

Publication	Publication Date	Title
NO790903L (no)	1979-09-18	Fremgangsmaate ved fremstilling av ornithin og argininsalter av forgrenede ketosyrer
NO794010L (no)	1980-06-12	Fremgangsmaate ved fremstilling av aminosyrederivater
DE2961139D1 (en)	1981-12-10	Process for the preparation of acetic acid anhydride
NO792823L (no)	1980-03-03	Fremgangsmaate ved fremstilling av nye arginiamidderivater
NO794069L (no)	1980-06-16	Fremgangsmaate ved fremstilling av terapeutisk virksomme imidayolderivater.
NO155098C (no)	1987-02-11	Analogifremgangsmaate ved fremstilling av farmasoeytisk aktive aza-bicyklo-oktan-karboksylsyrer.
IT1120442B (it)	1986-03-26	Procedimento per produrre acidi arilpiruvici
NO150879C (no)	1985-01-09	Fremgangsmaate for fremstilling av d-camforat av l-carnitinamid og d-camforat av d-carnitinamid
NO792474L (no)	1980-01-29	Fremgangsmaate ved fremstilling av indanyl-derivater
NO151201C (no)	1985-02-27	Fremgangsmaate for fremstilling av terapeutisk virksomme antigenderivater
NO790543L (no)	1980-04-17	Fremgangsmaate ved fremstilling av smaksstoff for naeringsmidler
NO791012L (no)	1979-10-01	Kontinuerlig fremgangsmaate for fremstilling av karboksylpersyrer
NO780777L (no)	1978-09-11	Fremgangsmaate ved fremstilling av 1-azaxanthon-3-carboxylsyrer
AR226446A1 (es)	1982-07-15	Procedimiento para preparar derivados de acidos fenilalcanoicos
DE2965361D1 (en)	1983-06-16	Process for the preparation of optically active alpha-amino acids and their derivatives
DK215079A (da)	1979-11-25	Fremgangsmaade til fremstilling af phenylaminothiothiopheneddikesyrer
IT7968724A0 (it)	1979-08-28	Procedimento per la preparazione di acidi 2 4 5 triclorofenossilici esenti da diossina
IT1110819B (it)	1986-01-06	Procedimento per la preparazione di acidi benzen-carbossilici
IT1128163B (it)	1986-05-28	Procedimento per la preparazione di acidi alcanoici
DK233379A (da)	1979-12-04	Fremgangsmaade til fremstilling af arylglyoxylsyrer
IL58048A0 (en)	1979-12-30	Process and intermediates for the preparation of carbazole derivatives
NO790328L (no)	1979-08-03	Fremgangsmaate ved fremstilling av derivater av nafthyl-1-eddiksyre.
NO792511L (no)	1980-02-01	Fremgangsmaate ved fremstilling av pyridoxinderivater
NL7907734A (nl)	1980-04-22	Werkwijze om ketozuren of hun esters te bereiden.
NO802306L (no)	1981-02-02	Fremgangsmaate ved fremstilling av 2-amino-3-(alkylthiobenzoyl)-fenyleddiksyrederivater