[go: up one dir, main page]

NO763567L - - Google Patents

Info

Publication number
NO763567L
NO763567L NO763567A NO763567A NO763567L NO 763567 L NO763567 L NO 763567L NO 763567 A NO763567 A NO 763567A NO 763567 A NO763567 A NO 763567A NO 763567 L NO763567 L NO 763567L
Authority
NO
Norway
Prior art keywords
alkyl
compound
formula
hydrogen
group
Prior art date
Application number
NO763567A
Other languages
English (en)
Norwegian (no)
Inventor
F Cassidy
G Wootton
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB43990/75A external-priority patent/GB1572184A/en
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of NO763567L publication Critical patent/NO763567L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/38—2-Pyrrolones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
NO763567A 1975-10-25 1976-10-19 NO763567L (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB43990/75A GB1572184A (en) 1975-10-25 1975-10-25 12-azaprostaglandins
GB2127876 1976-05-22

Publications (1)

Publication Number Publication Date
NO763567L true NO763567L (fr) 1977-04-26

Family

ID=26255241

Family Applications (2)

Application Number Title Priority Date Filing Date
NO763567A NO763567L (fr) 1975-10-25 1976-10-19
NO783766A NO783766L (no) 1975-10-25 1978-11-09 Mellomprodukter for anvendelse ved fremstilling av aromatiske prostaglandin-analoger.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO783766A NO783766L (no) 1975-10-25 1978-11-09 Mellomprodukter for anvendelse ved fremstilling av aromatiske prostaglandin-analoger.

Country Status (18)

Country Link
US (2) US4138407A (fr)
JP (1) JPS5257168A (fr)
AT (1) AT359658B (fr)
AU (1) AU506934B2 (fr)
CA (1) CA1085856A (fr)
DE (1) DE2647969A1 (fr)
DK (1) DK479176A (fr)
ES (1) ES452649A1 (fr)
FI (1) FI763000A (fr)
FR (1) FR2328464A1 (fr)
HU (1) HU179416B (fr)
IE (1) IE44180B1 (fr)
IL (2) IL50644A (fr)
NL (1) NL7611761A (fr)
NO (2) NO763567L (fr)
NZ (1) NZ182264A (fr)
PH (2) PH14168A (fr)
SE (1) SE417090B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1524818A (en) * 1974-11-29 1978-09-13 Beecham Group Ltd 12-azaprostaglandins
US4187312A (en) * 1975-10-25 1980-02-05 Beecham Group Limited 3-Hydroxy-4,4-dimethyl-5-pyrrolidone derivatives
NZ182264A (en) * 1975-10-25 1979-01-11 Beecham Group Ltd 2-carboxyalkyl-1-hydroxyalkyl-pyrrolidin-3,5-dione or-piperidin-3,6-dione derivatives prarmaceutical compostions
IL58384A0 (en) * 1978-10-14 1980-01-31 Beecham Group Ltd 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them
DE3317653A1 (de) * 1983-05-14 1984-11-15 Gödecke AG, 1000 Berlin 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile, verfahren zu deren herstellung sowie deren verwendung bei der prophylaxe und therapie thrombotischer zustaende
ZA96338B (en) * 1995-01-25 1996-10-24 Lonza Ag Process for the preparation of (1-hydroxycyclohexane)- acetonitrile
US7696243B2 (en) * 2004-12-06 2010-04-13 Merck Serono, S.A. Pyrrolidin-2-one derivatives for use as DP1 receptor agonists

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones
US4003911A (en) * 1975-09-26 1977-01-18 E. I. Du Pont De Nemours And Company Selected 3-pyrrolidinones and 2,4-pyrrolidindiones
US4187312A (en) * 1975-10-25 1980-02-05 Beecham Group Limited 3-Hydroxy-4,4-dimethyl-5-pyrrolidone derivatives
NZ182264A (en) * 1975-10-25 1979-01-11 Beecham Group Ltd 2-carboxyalkyl-1-hydroxyalkyl-pyrrolidin-3,5-dione or-piperidin-3,6-dione derivatives prarmaceutical compostions
NZ182263A (en) * 1975-10-25 1979-01-11 Beecham Group Ltd 2-carboxyalkyl-4,4-dimethyl-1-hydroxy-alkyl-pyrrolidin-3,5-dione derivativesand pharmaceutical compositions
US4177283A (en) * 1975-10-25 1979-12-04 Beecham Group Limited Aromatic prostaglandin analogues
NZ184084A (en) * 1976-05-22 1979-12-11 Beecham Group Ltd 2-carboxyalkyl-pyrrolid-in or piperidin-one or-dione derivatives and pharmaceutical compositions
IL58384A0 (en) * 1978-10-14 1980-01-31 Beecham Group Ltd 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them

Also Published As

Publication number Publication date
DE2647969A1 (de) 1977-05-05
NL7611761A (nl) 1977-04-27
AT359658B (de) 1980-11-25
FR2328464B1 (fr) 1978-12-22
IL50644A (en) 1981-06-29
ATA788776A (de) 1980-04-15
US4138407A (en) 1979-02-06
SE7611773L (sv) 1977-04-26
CA1085856A (fr) 1980-09-16
DK479176A (da) 1977-04-26
AU506934B2 (en) 1980-01-31
IL59758A0 (en) 1980-06-30
US4341789A (en) 1982-07-27
PH16143A (en) 1983-07-12
NZ182264A (en) 1979-01-11
SE417090B (sv) 1981-02-23
PH14168A (en) 1981-03-19
HU179416B (en) 1982-10-28
JPS5257168A (en) 1977-05-11
NO783766L (no) 1977-04-26
IL50644A0 (en) 1976-12-31
AU1868676A (en) 1978-04-20
FI763000A (fr) 1977-04-26
ES452649A1 (es) 1978-03-16
IE44180L (en) 1977-04-25
FR2328464A1 (fr) 1977-05-20
IE44180B1 (en) 1981-09-09

Similar Documents

Publication Publication Date Title
DE69622652T2 (de) Substituierte indolymethylen-oxindol-analoge als tyrosin kinase inhibitoren
JPH05320162A (ja) ペプチド性キヌクリジン
JPH0684336B2 (ja) 殺生物性芳香族化合物、その合成および医薬としてのその使用
WO1997049700A1 (fr) Derives de 2-(2-oxo-ethylidene)-imidazolidin-4-one et leur utilisation comme inhibiteurs de la farnesyl-proteine-transferase
US9962383B2 (en) Compounds, compositions and methods of agelastatin alkaloids
CA2306026A1 (fr) Derives de benzofurane utilises comme inhibiteurs de la phosphodiesterase iv
JP5616628B2 (ja) ピログルタミン酸誘導体の合成および使用
NO763567L (fr)
NO753935L (fr)
JPH0253430B2 (fr)
US4528289A (en) Corynantheine derivates, processes for their preparation, and their use
EP0564650A1 (fr) Derive de quinoline
KR950001040B1 (ko) 티오우레아 유도체 및 이를 함유하는 항균제 및 항궤양제
JPH06503549A (ja) 殺生物性ヘテロ多環状化合物およびそれらの医療における使用
EP1101765B1 (fr) Nouveaux composés analogues de la camptothécine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
NO763566L (fr)
JP2024542212A (ja) 治療薬としてのペプチドチューブリン阻害剤のペプチドコンジュゲート
JPH02138252A (ja) ５‐置換１‐〔４‐（１‐ピロリジニル）‐２‐ブチニル〕‐２‐ピロリドン類および類似化合物
US7405309B2 (en) Pyranone derivatives useful for treating cancer
ES2232147T3 (es) Derivados de lk6-a.
US4868204A (en) Mycalamide compounds, compositions thereof and methods of preparation and use
US10844052B2 (en) LLS compounds for treatment of cancer
US4510159A (en) (+)-Cyanidan-3-ol derivatives, pharmaceutical preparations that contain such compounds, and the use of the latter to treat liver or venous diseases
US4177283A (en) Aromatic prostaglandin analogues
US20060173069A1 (en) Therapeutic agent for hyperpotassemia and bone disease