NO316926B1 - Fremgangsmate for fremstilling av et dimerisk biologisk aktivt TGF-<beta>-protein - Google Patents
Fremgangsmate for fremstilling av et dimerisk biologisk aktivt TGF-<beta>-protein Download PDFInfo
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- NO316926B1 NO316926B1 NO19970325A NO970325A NO316926B1 NO 316926 B1 NO316926 B1 NO 316926B1 NO 19970325 A NO19970325 A NO 19970325A NO 970325 A NO970325 A NO 970325A NO 316926 B1 NO316926 B1 NO 316926B1
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- tgf
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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Applications Claiming Priority (2)
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EP94810438 | 1994-07-25 | ||
PCT/EP1995/002718 WO1996003432A1 (en) | 1994-07-25 | 1995-07-12 | Novel process for the production of biologically active dimeric protein |
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NO970325D0 NO970325D0 (no) | 1997-01-24 |
NO970325L NO970325L (no) | 1997-03-06 |
NO316926B1 true NO316926B1 (no) | 2004-06-28 |
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NO19970325A NO316926B1 (no) | 1994-07-25 | 1997-01-24 | Fremgangsmate for fremstilling av et dimerisk biologisk aktivt TGF-<beta>-protein |
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US (1) | US6057430A (fi) |
EP (1) | EP0775159B1 (fi) |
JP (2) | JP3923516B2 (fi) |
KR (1) | KR100432839B1 (fi) |
AT (1) | ATE207933T1 (fi) |
AU (1) | AU690311B2 (fi) |
CA (1) | CA2194582C (fi) |
DE (1) | DE69523605T2 (fi) |
DK (1) | DK0775159T3 (fi) |
ES (1) | ES2166401T3 (fi) |
FI (1) | FI118083B (fi) |
HU (1) | HU222830B1 (fi) |
IL (1) | IL114701A (fi) |
NO (1) | NO316926B1 (fi) |
NZ (1) | NZ290373A (fi) |
PT (1) | PT775159E (fi) |
TW (1) | TW440566B (fi) |
WO (1) | WO1996003432A1 (fi) |
ZA (1) | ZA956138B (fi) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
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TW517059B (en) * | 1994-07-25 | 2003-01-11 | Ciba Geigy Ag | New process for the production of biologically active protein |
WO1997023638A1 (fr) * | 1995-12-21 | 1997-07-03 | Ajinomoto Co., Inc. | Procede pour replier l'activine a humaine |
DE19906096A1 (de) | 1999-02-13 | 2000-08-17 | Walter Sebald | Protein mit einem Heparin-bindenden Epitop |
EP1273655A4 (en) * | 2000-03-30 | 2004-08-04 | Takeda Chemical Industries Ltd | METHOD FOR PRODUCING A RECOMBINANT PROTEIN |
AU2001246393A1 (en) * | 2000-03-31 | 2001-10-08 | Vaccine Chip Technology Aps | Immunostimulating properties of a fragment of tgf-beta |
US7572474B2 (en) * | 2005-06-01 | 2009-08-11 | Mead Johnson Nutrition Company | Method for simulating the functional attributes of human milk oligosaccharides in formula-fed infants |
US8075934B2 (en) * | 2008-10-24 | 2011-12-13 | Mead Johnson Nutrition Company | Nutritional composition with improved digestibility |
GB0514262D0 (en) * | 2005-07-12 | 2005-08-17 | Renovo Ltd | Promotion of epithelial regeneration |
GB0604966D0 (en) | 2006-03-11 | 2006-04-19 | Renovo Ltd | Medicaments and proteins |
GB0604964D0 (en) | 2006-03-11 | 2006-04-19 | Renovo Ltd | Protein folding |
GB0604938D0 (en) | 2006-03-11 | 2006-04-19 | Renovo Ltd | Proteins, nucleic acids and medicaments |
GB0617816D0 (en) * | 2006-09-11 | 2006-10-18 | Renovo Ltd | Nucleic acids and methods of protein expression |
US8986769B2 (en) | 2008-10-24 | 2015-03-24 | Mead Johnson Nutrition Company | Methods for preserving endogenous TGF-β |
WO2018122794A1 (en) | 2016-12-30 | 2018-07-05 | Biogend Therapeutics Co., Ltd. | Recombinant polypeptides and nucleic acid molecules, compositions, and methods of making and uses thereof |
EP3852820B1 (en) * | 2018-09-17 | 2024-11-20 | Board of Regents, The University of Texas System | Compositions and methods for treating bone injury |
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US4731440A (en) * | 1985-02-22 | 1988-03-15 | Monsanto Company | Method of somatotropin solubilization using dimethylsulfone and naturation |
JPH0759598B2 (ja) * | 1986-02-14 | 1995-06-28 | 藤沢薬品工業株式会社 | ヒトインスリン様成長因子▲i▼の製造法 |
EP0293785A3 (en) * | 1987-05-29 | 1990-05-02 | Oncogen Limited Partnership | Cloning and expression of simian transforming growth factor-ss1 |
US5061786A (en) * | 1989-05-25 | 1991-10-29 | Genentech, Inc. | Biologically active polypeptides based on transforming growth factor-β |
GB8927546D0 (en) * | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
US5144006A (en) * | 1991-06-13 | 1992-09-01 | The Rockefeller University | Oxidative folding of peptide and protein substrates using hydrocarbon sulfoxides |
AU2738392A (en) * | 1991-11-11 | 1993-05-13 | Ciba-Geigy Ag | Novel hybrid transforming growth factors |
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1995
- 1995-07-11 TW TW084107188A patent/TW440566B/zh not_active IP Right Cessation
- 1995-07-12 WO PCT/EP1995/002718 patent/WO1996003432A1/en active IP Right Grant
- 1995-07-12 ES ES95926857T patent/ES2166401T3/es not_active Expired - Lifetime
- 1995-07-12 CA CA002194582A patent/CA2194582C/en not_active Expired - Fee Related
- 1995-07-12 NZ NZ290373A patent/NZ290373A/en not_active IP Right Cessation
- 1995-07-12 DE DE69523605T patent/DE69523605T2/de not_active Expired - Lifetime
- 1995-07-12 JP JP50540096A patent/JP3923516B2/ja not_active Expired - Fee Related
- 1995-07-12 AU AU31095/95A patent/AU690311B2/en not_active Ceased
- 1995-07-12 KR KR1019970700476A patent/KR100432839B1/ko not_active IP Right Cessation
- 1995-07-12 HU HU9700210A patent/HU222830B1/hu not_active IP Right Cessation
- 1995-07-12 PT PT95926857T patent/PT775159E/pt unknown
- 1995-07-12 EP EP95926857A patent/EP0775159B1/en not_active Expired - Lifetime
- 1995-07-12 DK DK95926857T patent/DK0775159T3/da active
- 1995-07-12 AT AT95926857T patent/ATE207933T1/de not_active IP Right Cessation
- 1995-07-24 IL IL11470195A patent/IL114701A/xx not_active IP Right Cessation
- 1995-07-24 ZA ZA956138A patent/ZA956138B/xx unknown
-
1997
- 1997-01-20 FI FI970229A patent/FI118083B/fi active IP Right Grant
- 1997-01-24 NO NO19970325A patent/NO316926B1/no not_active IP Right Cessation
-
1998
- 1998-07-28 US US09/123,233 patent/US6057430A/en not_active Expired - Fee Related
-
2006
- 2006-11-09 JP JP2006304295A patent/JP2007031453A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
ZA956138B (en) | 1996-03-07 |
FI970229A0 (fi) | 1997-01-20 |
JP2007031453A (ja) | 2007-02-08 |
AU3109595A (en) | 1996-02-22 |
KR100432839B1 (ko) | 2004-08-30 |
DK0775159T3 (da) | 2002-02-11 |
IL114701A0 (en) | 1995-11-27 |
ES2166401T3 (es) | 2002-04-16 |
US6057430A (en) | 2000-05-02 |
EP0775159B1 (en) | 2001-10-31 |
FI118083B (fi) | 2007-06-29 |
EP0775159A1 (en) | 1997-05-28 |
NZ290373A (en) | 1998-04-27 |
IL114701A (en) | 2005-11-20 |
TW440566B (en) | 2001-06-16 |
HUT76668A (en) | 1997-10-28 |
HU222830B1 (hu) | 2003-11-28 |
JPH11505506A (ja) | 1999-05-21 |
ATE207933T1 (de) | 2001-11-15 |
FI970229A (fi) | 1997-01-20 |
JP3923516B2 (ja) | 2007-06-06 |
DE69523605D1 (de) | 2001-12-06 |
PT775159E (pt) | 2002-04-29 |
NO970325D0 (no) | 1997-01-24 |
CA2194582A1 (en) | 1996-02-08 |
NO970325L (no) | 1997-03-06 |
AU690311B2 (en) | 1998-04-23 |
CA2194582C (en) | 2008-09-02 |
DE69523605T2 (de) | 2002-07-11 |
WO1996003432A1 (en) | 1996-02-08 |
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MM1K | Lapsed by not paying the annual fees |