NO20091627L - Procedure for Identifying Potential Biomarkers and Drug Templates in Brain Plasticity-Related Disorders - Google Patents
Procedure for Identifying Potential Biomarkers and Drug Templates in Brain Plasticity-Related DisordersInfo
- Publication number
- NO20091627L NO20091627L NO20091627A NO20091627A NO20091627L NO 20091627 L NO20091627 L NO 20091627L NO 20091627 A NO20091627 A NO 20091627A NO 20091627 A NO20091627 A NO 20091627A NO 20091627 L NO20091627 L NO 20091627L
- Authority
- NO
- Norway
- Prior art keywords
- related disorders
- potential biomarkers
- brain plasticity
- procedure
- identifying potential
- Prior art date
Links
- 239000000090 biomarker Substances 0.000 title abstract 3
- 210000004556 brain Anatomy 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 239000003596 drug target Substances 0.000 abstract 2
- 241000255581 Drosophila <fruit fly, genus> Species 0.000 abstract 1
- 241000255601 Drosophila melanogaster Species 0.000 abstract 1
- 240000005561 Musa balbisiana Species 0.000 abstract 1
- 235000018290 Musa x paradisiaca Nutrition 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 230000008579 epileptogenesis Effects 0.000 abstract 1
- 238000011223 gene expression profiling Methods 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Oppfinnelsen angår identifikasjon av potensielle biomarkører og legemiddelmål i hjerneplastisitet relaterte forstyrrelser. Særlig beskriver oppfinnelsen en systemnivåmodell for hjerneplastisitetsrelaterte forstyrrelser i bananfluen Drosophila melanogaster, som derved identifiserer potensielle biomarkører og legemiddelmål i epileptogenese og assosierte tilstander. Oppfinnelsen tilveiebringer også en måte for å screene terapeutiske midler mot epilepsi og relaterte forstyrrelser ved anvendelse av genekspresjonsprofilering i Drosophila.The invention relates to the identification of potential biomarkers and drug targets in brain plasticity related disorders. In particular, the invention discloses a system level model for brain plasticity-related disorders in the banana fly Drosophila melanogaster, thereby identifying potential biomarkers and drug targets in epileptogenesis and associated conditions. The invention also provides a means for screening therapeutic agents against epilepsy and related disorders using gene expression profiling in Drosophila.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN2193DE2006 | 2006-10-05 | ||
| PCT/IN2007/000452 WO2008041244A2 (en) | 2006-10-05 | 2007-10-01 | A method for the identification of potential biomarkers and drug targets in brain plasticity related disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20091627L true NO20091627L (en) | 2009-07-02 |
Family
ID=39198212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20091627A NO20091627L (en) | 2006-10-05 | 2009-04-23 | Procedure for Identifying Potential Biomarkers and Drug Templates in Brain Plasticity-Related Disorders |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP2076608A2 (en) |
| NO (1) | NO20091627L (en) |
| WO (1) | WO2008041244A2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108977549B (en) * | 2018-07-04 | 2021-01-15 | 中国农业大学 | Primer pair for detecting expression quantity of CG5210 gene of fruit fly |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6291739B1 (en) * | 2000-03-24 | 2001-09-18 | Council Of Scientific And Industrial Research | Method for screening of potential anti-epileptic drugs using a Drosophila melanogaster model |
-
2007
- 2007-10-01 WO PCT/IN2007/000452 patent/WO2008041244A2/en active Application Filing
- 2007-10-01 EP EP07827592A patent/EP2076608A2/en not_active Withdrawn
-
2009
- 2009-04-23 NO NO20091627A patent/NO20091627L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2008041244A2 (en) | 2008-04-10 |
| WO2008041244A3 (en) | 2008-07-31 |
| WO2008041244B1 (en) | 2008-10-09 |
| EP2076608A2 (en) | 2009-07-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |