NO20082425L - Formuleringer omfattende jorumycin-, reni-eramycin-, safracin- eller saframycin-relaterte forbindelser for behandling av proliferative sykdommer - Google Patents
Formuleringer omfattende jorumycin-, reni-eramycin-, safracin- eller saframycin-relaterte forbindelser for behandling av proliferative sykdommerInfo
- Publication number
- NO20082425L NO20082425L NO20082425A NO20082425A NO20082425L NO 20082425 L NO20082425 L NO 20082425L NO 20082425 A NO20082425 A NO 20082425A NO 20082425 A NO20082425 A NO 20082425A NO 20082425 L NO20082425 L NO 20082425L
- Authority
- NO
- Norway
- Prior art keywords
- formulations
- jorumycin
- safracin
- saframycin
- related compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4995—Pyrazines or piperazines forming part of bridged ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Jorumycin-, renieramycin-, safracin- og saframycinrelaterte forbindelsesformuleringer, fremgangsmåter for fremstilling av disse, fremstillingsartikler og sett med slike- formuleringer, og metoder for behandling av proliferative sykdommer med de samme formuleringer er tilveiebrakt.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0522082.7A GB0522082D0 (en) | 2005-10-31 | 2005-10-31 | Formulations |
PCT/GB2006/050362 WO2007052076A2 (en) | 2005-10-31 | 2006-10-30 | Formulations comprising jorumycin-, reni eramycin-, safracin- or saframycin-related compounds for treating proliferative diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20082425L true NO20082425L (no) | 2008-07-25 |
NO341057B1 NO341057B1 (no) | 2017-08-14 |
Family
ID=35515969
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20082425A NO341057B1 (no) | 2005-10-31 | 2008-05-30 | Farmasøytisk sammensetning, som omfatter et disakkarid og en jorumycin-, renieramycin-, safracin- eller saframycin-beslektet forbindelse, fremgangsmåte for fremstilling av en ampulle inneholdende en lyofilisert formulering derav, fremgangsmåte for redusering av dannelsen av urenheter i formuleringen, fremgangsmåte for fremstilling av en løsning derav for intravenøs infusjon, anvendelse derav ved fremstilling av et medikament for behandling av kreft. |
Country Status (24)
Country | Link |
---|---|
US (1) | US9192568B2 (no) |
EP (1) | EP1968592B1 (no) |
JP (1) | JP5197373B2 (no) |
KR (1) | KR101434230B1 (no) |
CN (1) | CN101300011B (no) |
AT (1) | ATE549023T1 (no) |
AU (1) | AU2006310260C1 (no) |
CA (1) | CA2625096C (no) |
DK (1) | DK1968592T3 (no) |
ES (1) | ES2383967T3 (no) |
GB (1) | GB0522082D0 (no) |
HK (1) | HK1122743A1 (no) |
HR (1) | HRP20120478T1 (no) |
IL (1) | IL190774A (no) |
NO (1) | NO341057B1 (no) |
NZ (1) | NZ567291A (no) |
PL (1) | PL1968592T3 (no) |
PT (1) | PT1968592E (no) |
RS (1) | RS52312B (no) |
RU (1) | RU2429845C2 (no) |
SI (1) | SI1968592T1 (no) |
UA (1) | UA97629C2 (no) |
WO (1) | WO2007052076A2 (no) |
ZA (1) | ZA200803420B (no) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0117402D0 (en) * | 2001-07-17 | 2001-09-05 | Pharma Mar Sa | New antitumoral derivatives of et-743 |
GB0708691D0 (en) * | 2007-05-04 | 2007-06-13 | Pharma Mar Sa | Anticancer treatments a |
US8435992B2 (en) * | 2008-05-16 | 2013-05-07 | Pharma Mar S.A. | Multiple myeloma treatments |
AU2009246130A1 (en) * | 2008-05-16 | 2009-11-19 | Pharma Mar, S.A. | Combination therapy with PM00 104 and another antitumor agent |
WO2011048210A1 (en) | 2009-10-22 | 2011-04-28 | Pharma Mar, S.A. | PDGFR-α AS RESPONSE MARKER FOR PM00104 TREATMENT |
HUE060783T2 (hu) | 2011-04-28 | 2023-04-28 | Oncopeptides Ab | Citotoxikus dipeptidek liofilizált készítménye |
CN108685860B (zh) | 2012-10-26 | 2022-04-05 | 肿瘤多肽股份公司 | 美法仑氟灭酰胺的冻干制剂 |
JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
US10526334B2 (en) | 2017-07-19 | 2020-01-07 | California Institute Of Technology | Methods for preparing bis-tetrahydroisoquinoline-containing compounds |
WO2022186221A1 (ja) * | 2021-03-03 | 2022-09-09 | 国立大学法人東京大学 | マクロ環含有新規テトラヒドロイソキノリンアルカロイド化合物 |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5089273A (en) * | 1986-06-09 | 1992-02-18 | Board Of Trustees Of The University Of Illinois | Ecteinascidins 729, 743, 745, 759A, 759B and 770 |
US5256663A (en) * | 1986-06-09 | 1993-10-26 | The Board Of Trustees Of The University Of Illinois | Compositions comprising ecteinascidins and a method of treating herpes simplex virus infections therewith |
US5149804A (en) * | 1990-11-30 | 1992-09-22 | The Board Of Trustees Of The University Of Illinois | Ecteinascidins 736 and 722 |
DE3635711A1 (de) * | 1986-10-21 | 1988-04-28 | Knoll Ag | 5-nitrobenzo(de)isochinolin-1,3-dione, ihre herstellung und verwendung |
US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
US5336669A (en) | 1991-12-10 | 1994-08-09 | Erbamont, Inc. | Cyclophosphamide monohydrate and lactose |
FR2697752B1 (fr) * | 1992-11-10 | 1995-04-14 | Rhone Poulenc Rorer Sa | Compositions antitumorales contenant des dérivés du taxane. |
US5478932A (en) * | 1993-12-02 | 1995-12-26 | The Board Of Trustees Of The University Of Illinois | Ecteinascidins |
US20040059112A1 (en) * | 1994-02-18 | 2004-03-25 | Rinehart Kenneth L. | Ecteinascidins |
GB9508195D0 (en) * | 1995-04-20 | 1995-06-07 | Univ British Columbia | Novel biologically active compounds and compositions,their use and derivation |
DE19605212A1 (de) * | 1996-02-13 | 1997-08-14 | Basf Ag | Phosphordotiertes Silberkatalysator-Festbett |
US5721362A (en) * | 1996-09-18 | 1998-02-24 | President And Fellows Of Harvard College | Process for producing ecteinascidin compounds |
US5985876A (en) | 1997-04-15 | 1999-11-16 | Univ Illinois | Nucleophile substituted ecteinascidins and N-oxide ecteinascidins |
AU7589898A (en) | 1997-05-21 | 1998-12-11 | Genentech Inc. | Novel administration of thrombopoietin |
DE69936845T2 (de) | 1998-04-06 | 2008-05-08 | The Board Of Trustees Of The University Of Illinois, Urbana | Halbsynthetische ectein-ascidine |
US6316214B1 (en) | 1998-05-11 | 2001-11-13 | The Board Of Trustees Of The University Of Illinois | ETM-775 metabolite of ecteinascidin 743 |
JP2000081438A (ja) | 1998-06-25 | 2000-03-21 | Sekisui Chem Co Ltd | 被験者の癌化学療法による免疫機能低下の測定方法 |
US6124292A (en) * | 1998-09-30 | 2000-09-26 | President And Fellows Of Harvard College | Synthetic analogs of ecteinascidin-743 |
MY164077A (en) * | 1999-05-13 | 2017-11-30 | Pharma Mar Sa | Compositions and uses of et743 for treating cancer |
AR035842A1 (es) | 1999-05-14 | 2004-07-21 | Pharma Mar Sa | Metodo de hemisintesis para la formacion de compuestos intermediarios y derivados y de estructuras relacionadas con la ecteinascidina y de tetrahidroisoquinolinfenoles y compuestos intermediarios de aplicacion en dicho metodo |
US7202361B2 (en) | 2000-04-12 | 2007-04-10 | Pharmamar | Antitumoral ecteinascidin derivatives |
MXPA02011319A (es) * | 2000-05-15 | 2003-06-06 | Pharma Mar Sa | Analogos antitumorales de ecteinascidina 743. |
US7420051B2 (en) * | 2000-05-15 | 2008-09-02 | Pharma Mar, S.A. | Synthetic process for the manufacture of an ecteinaschidin compound |
WO2002014554A2 (en) * | 2000-08-11 | 2002-02-21 | City Of Hope | The anti-neoplastic agent et-743 inhibits trans activation by sxr |
MXPA03003704A (es) * | 2000-10-31 | 2004-05-04 | Pharma Mar Sa | Formulacion de kahalalide f. |
WO2002040477A2 (en) * | 2000-11-03 | 2002-05-23 | President And Fellows Of Harvard College | Saframycins, analogues and uses thereof |
CA2428160C (en) | 2000-11-06 | 2009-10-13 | Pharma Mar, S.A. | Compositions for antitumor treatment containing ecteinascidin 743 |
JP2004521122A (ja) | 2001-01-25 | 2004-07-15 | ブリストル−マイヤーズ スクイブ カンパニー | エポチロン類似体の非経口製剤 |
WO2002064843A1 (en) * | 2001-02-09 | 2002-08-22 | The Regents Of The University Of California | Ecteinascidin family compounds: compositions and methods |
RU2284184C2 (ru) * | 2001-03-06 | 2006-09-27 | Бристол-Маерс Сквибб Компани | Способ лечения рака |
AU2002242561A1 (en) | 2001-03-30 | 2002-10-15 | Shire Biochem Inc. | Methods of treating cancer using cyplastin combined with a dioxolane nucleoside such as troxacitabine |
GB0121285D0 (en) | 2001-09-03 | 2001-10-24 | Cancer Res Ventures Ltd | Anti-cancer combinations |
RU2306933C2 (ru) | 2001-10-19 | 2007-09-27 | Фарма Мар, С.А. | Улучшенная схема применения противоопухолевого соединения в терапии рака |
US20040019027A1 (en) * | 2002-04-12 | 2004-01-29 | Barry Forman | Method of treating cerebrotendinous xanthomatosis |
GB0218813D0 (en) | 2002-08-13 | 2002-09-18 | Pharma Mar Sa | DNA sequences from an endosymbiont and their uses |
GB0229793D0 (en) | 2002-12-20 | 2003-01-29 | Pharma Mar Sa | The gene cluster involved in safracin biosynthesis and its uses for genetic engineering |
GB0312407D0 (en) * | 2003-05-29 | 2003-07-02 | Pharma Mar Sau | Treatment |
US7251892B2 (en) * | 2003-07-09 | 2007-08-07 | Temper Corporation | Bearing assembly spacer adjustable system and method for adjusting a spacer |
GB0324201D0 (en) * | 2003-10-15 | 2003-11-19 | Pharma Mar Sau | Improved antitumoral combinations |
US7622458B2 (en) | 2003-11-13 | 2009-11-24 | Pharma Mar, S.A.U. | Combination of ET-743 and a 5-fluorouracil pro-drug for cancer treatment |
US20080255132A1 (en) * | 2003-11-14 | 2008-10-16 | Eric Rowinsky | Combination Therapy Comprising the Use of Et-743 and Paclitaxel for Treating Cancer |
GB0326486D0 (en) * | 2003-11-14 | 2003-12-17 | Pharma Mar Sau | Combination treatment |
WO2005118584A2 (en) * | 2004-05-26 | 2005-12-15 | Axys Pharmaceuticals, Inc. | Saframycin analogs as therapeutic agents in the treatment of cancer |
NZ552607A (en) * | 2004-07-09 | 2009-07-31 | Pharma Mar Sa | Prognostic molecular markers |
US20080242670A2 (en) * | 2004-09-29 | 2008-10-02 | Pharma Mar S.A., Sociedad Unipersonal | Anti-Inflammatory Agents |
US20090117176A1 (en) * | 2004-10-26 | 2009-05-07 | Pharma Mar, S.A. Sociedad Unipersonal | Anticancer Treatments |
NZ554761A (en) * | 2004-10-29 | 2010-01-29 | Pharma Mar Sa | Formulations comprising ecteinascidin and a disaccharide |
WO2006066183A2 (en) * | 2004-12-16 | 2006-06-22 | Axys Pharmaceuticals, Inc. | Novel saframycin analogs as therapeutic agents |
AU2006318226A1 (en) * | 2005-11-25 | 2007-05-31 | Pharma Mar, S.A. Sociedad Unipersonal | Use of PARP-1 inhibitors |
AU2007249281A1 (en) * | 2006-05-12 | 2007-11-22 | Pharma Mar, S.A. | Anticancer treatments with a combination of docetaxel and ecteinascidin |
-
2005
- 2005-10-31 GB GBGB0522082.7A patent/GB0522082D0/en not_active Ceased
-
2006
- 2006-10-30 SI SI200631346T patent/SI1968592T1/sl unknown
- 2006-10-30 AT AT06795019T patent/ATE549023T1/de active
- 2006-10-30 RU RU2008121716/15A patent/RU2429845C2/ru not_active IP Right Cessation
- 2006-10-30 PL PL06795019T patent/PL1968592T3/pl unknown
- 2006-10-30 NZ NZ567291A patent/NZ567291A/en not_active IP Right Cessation
- 2006-10-30 UA UAA200807478A patent/UA97629C2/ru unknown
- 2006-10-30 CA CA2625096A patent/CA2625096C/en not_active Expired - Fee Related
- 2006-10-30 PT PT06795019T patent/PT1968592E/pt unknown
- 2006-10-30 ES ES06795019T patent/ES2383967T3/es active Active
- 2006-10-30 RS RS20120235A patent/RS52312B/en unknown
- 2006-10-30 WO PCT/GB2006/050362 patent/WO2007052076A2/en active Application Filing
- 2006-10-30 EP EP06795019A patent/EP1968592B1/en active Active
- 2006-10-30 DK DK06795019.6T patent/DK1968592T3/da active
- 2006-10-30 US US12/091,540 patent/US9192568B2/en not_active Expired - Fee Related
- 2006-10-30 CN CN2006800404704A patent/CN101300011B/zh not_active Expired - Fee Related
- 2006-10-30 KR KR1020087010283A patent/KR101434230B1/ko not_active Expired - Fee Related
- 2006-10-30 JP JP2008537207A patent/JP5197373B2/ja not_active Expired - Fee Related
- 2006-10-30 AU AU2006310260A patent/AU2006310260C1/en not_active Ceased
-
2008
- 2008-04-10 IL IL190774A patent/IL190774A/en not_active IP Right Cessation
- 2008-04-17 ZA ZA200803420A patent/ZA200803420B/xx unknown
- 2008-05-30 NO NO20082425A patent/NO341057B1/no not_active IP Right Cessation
-
2009
- 2009-02-06 HK HK09101104.2A patent/HK1122743A1/xx not_active IP Right Cessation
-
2012
- 2012-06-06 HR HRP20120478TT patent/HRP20120478T1/hr unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20082425L (no) | Formuleringer omfattende jorumycin-, reni-eramycin-, safracin- eller saframycin-relaterte forbindelser for behandling av proliferative sykdommer | |
TW200621256A (en) | Formulations | |
NO20083002L (no) | Fremgangsmate for anvendelse av CD40-bindende forbindelser | |
WO2009105513A3 (en) | Novel compounds and methods for therapy | |
NO20070782L (no) | Tetrapeptidanaloger. | |
DE602006018057D1 (de) | Substituierte chinolone und verwendungsverfahren | |
ATE547102T1 (de) | Carbolin-derivate zur behandlung von krebs | |
ATE432281T1 (de) | Pyrrolotriazin-kinasehemmer | |
MX2009009761A (es) | Composiciones y estuches para tratamiento de la influenza. | |
EA200802332A1 (ru) | Пирролопиримидины и их применение | |
ATE527241T1 (de) | Pyridiazinonderivate zur behandlung von tumoren | |
CL2009000200A1 (es) | Compuestos derivados de 2,7-naftiridinas-1-ona, mediadores de syk; composicion farmaceutica; y uso en el tratamiento de una enfermedad inflamatoria, respiratoria, proliferativa celular o autoinmune. | |
TNSN06321A1 (en) | Beta-carbolines useful for treating inflammatory disease | |
WO2007047608A3 (en) | Fibrin targeted therapeutics | |
WO2007097981A3 (en) | Alpha carbolines and uses thereof | |
WO2007120333A3 (en) | Tetracyclic kinase inhibitors | |
WO2006109301A3 (en) | Molecules and methods of using same for treating mcp-1/ccr2 associated diseases | |
ATE433459T1 (de) | Desoxo-nonadepsipeptide | |
ATE481392T1 (de) | Benzimidazolderivate zur behandlung entzündlicher erkrankungen | |
DE602005015329D1 (de) | Rutheniumkomplexe zur krebsbehandlung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |